Echinacea - Doxycycline Interaction
Herbal: Echinacea
Also Known As: American Cone Flower, Black Sampson, Black Susans, Comb Flower, Coneflower, Echinaceawurzel, Hedgehog, Igelkopfwurzel, Indian Head, Kansas Snakeroot
Drug: Doxycycline
Brand names:
Vibra-Tabs, Vibramycin, Doryx, Monodox, Doxycin, Doxy, Doxylin, Doxy-D, Periostat, Doxycycline Injection, Oracea, Xyrosa
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Apr 13, 2024
Interaction Details
There were no interactions found between Doxycycline and Echinacea. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Pharmacist Analysis
Echinacea can interact with a number of different drugs due to its effects on CYP metabolizing enzymes in the liver.
Doxycycline and tetracycline undergo minimal hepatic metabolism, and most of the drug is excreted in its unchanged form in the urine and feces. Metabolism of these drugs is generally not affected by hepatic dysfunction, and dose adjustments are not usually necessary in patients with mild to moderate liver disease or in those who take drugs that can affect CYP metabolizing enzymes.
Based on this information, there is no known interaction between echinacea and tetracycline or doxycycline.
- Dr. Brian Staiger, PharmDEchinacea Overview
Echinacea is a type of flowering plant that belongs to the daisy family and is native to cental and eastern North America. It is known for its purple, cone-shaped flowers. In traditional medicine, echinacea has been used to treat a variety of conditions, including colds, flu, and other respiratory infections. It is believed to work by stimulating the immune system and helping the body to fight off infection. Some studies have suggested that echinacea may be effective at reducing the severity and duration of colds and other respiratory infections, but more research is needed to confirm its effectiveness.
Doxycycline Overview
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Doxycycline is used to treat a variety of infections caused by certain types of bacteria. Doxycycline is also used to treat or prevent anthrax (a serious infection that may be spread on purpose as part of a bioterror attack) in people who may have been exposed to anthrax in the air and to treat plague and tuleramia (serious infections that may be spread on purpose as part of a bioterror attack). It is also used to prevent malaria. Doxycycline is also used along with other medications to treat acne and rosacea (a skin disease that causes redness, flushing, and pimples on the face). Doxycycline (Oracea) is used only to treat pimples and bumps caused by rosacea. Doxycycline is in a class of medications called tetracycline antibiotics. It works to treat infections by preventing the growth and spread of bacteria. It works to treat acne by killing the bacteria that infects pores and decreasing a certain natural oily substance that causes acne. It works to treat rosacea by decreasing the inflammation that causes this condition.
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Antibiotics such as doxycycline will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.
Echinacea - More Interactions
Echinacea interacts with 768 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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