Garden Cress - Vascepa (Icosapent Ethyl (prescription drug)) Interaction
Herbal: Garden Cress
Also Known As: Lepidium sativum, Berro Hortelano, Cresson Alénois, Cresson de Jardin, Lepidio, Mastuerzo
Drug: Icosapent Ethyl (prescription drug)
Brand names:
Vascepa
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jun 02, 2024
Interaction Details
Icosapent Ethyl (prescription drug) is classified as belonging to the following category: Anticoagulant/Antiplatelet Drugs
Theoretically, garden cress seed may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Animal research suggests that garden cress seed extract can increase bleeding time when used in combination with the antiplatelet agent clopidogrel. This has not been shown in humans and it is unclear if garden cress seed itself has anticoagulant or antiplatelet effects.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Alkharfy K, Jan B, Alotaibi K, et al. Clopidogrel-herb Interactions: A Pharmacokinetic and Pharmacodynamic Assessment in a Rat Model. Curr Drug Metab 2021;22(12):969-977.
Garden Cress Overview
Garden cress (Lepidium sativum) is a fast-growing herb that belongs to the Brassicaceae family. It is native to Europe and Asia and is cultivated for its flavorful, spicy leaves and seeds. Garden cress is often used in salads, sandwiches, and other dishes as a garnish or condiment.
Garden cress is rich in vitamins and minerals, including vitamin C, folic acid, and iron. It is also purported to have various health benefits, including improving digestion, reducing inflammation, and boosting the immune system.
Icosapent Ethyl (prescription drug) Overview
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Icosapent ethyl is used together with lifestyle changes (diet, weight loss, exercise) to reduce the amount of triglycerides (a fat-like substance) in the blood. It is also used along with cholesterol-lowering medications (statins) to decrease the risk of a heart attack, a stroke, or other heart problems that require hospitalization in certain adults with high triglyceride levels and heart disease or diabetes with 2 or more other heart disease risk factors. Icosapent ethyl is in a class of medications called antilipemic or lipid-regulating agents. Icosapent ethyl may work by decreasing the amount of triglycerides and other fats made in the liver.
Garden Cress - More Interactions
Garden Cress interacts with 392 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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