Hawthorn - Lanoxin (Digoxin) Interaction
Herbal: Hawthorn
Also Known As: Aubepine, Aubépine, Aubépine Blanche, Aubépine Épineuse, Bianco Spino, Bois de Mai, Cenellier, Chinese Hawthorn, Crataegi Flos, Crataegi Folium, Crataegi Folium Cum Flore, Crataegi Fructus, Crataegus, English Hawthorn, Epine Blanche, Epine de Mai, Espino Blanco, Fructus C
Drug: Digoxin
Brand names:
Lanoxicaps, Lanoxin, Digitek
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jul 22, 2023
Interaction Details
Digoxin is classified as belonging to the following category: Digoxin (Lanoxin)
Theoretically, hawthorn might potentiate the effects and adverse effects of digoxin.
Hawthorn appears to improve cardiac output; however, hawthorn does not appear to affect digoxin pharmacokinetics.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Chang Q, Zuo Z, Harrison F, Chow MS. Hawthorn. J Clin Pharmacol 2002;42:605-12.
- Tankanow R, Tamer HR, Streetman DS, et al. Interaction study between digoxin and a preparation of hawthorn (Crataegus oxyacantha). J.Clin.Pharmacol. 2003;43:637-42.
Hawthorn Overview
Hawthorn is a shrub native to Europe, Asia, and North America. It is a member of the rose family and is known for its thorny branches and small, white or pink flowers, which bloom in the spring. The fruit, called a haw, is a small red berry that is edible and often used in traditional medicine. Hawthorn has been used to treat a variety of conditions, including gastrointestinal discomfort, heart disease, high blood pressure, and chest pain. For its purported blood pressure-lowering abilities, it is thought to work by dilating blood vessels and improving blood flow to the heart. Hawthorn dietary supplements are typically standardized extracts of the berry, leaf and flower of the plant.
Digoxin Overview
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Digoxin is used to treat heart failure and abnormal heart rhythms (arrhythmias). It helps the heart work better and it helps control your heart rate.
Hawthorn - More Interactions
Hawthorn interacts with 186 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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