Allspice Interactions Overview

Additional Details

Is Allspice Safe? Are There Any Warnings?

• Allspice is considered likely safe when used orally in amounts commonly found in foods, and it has Generally Recognized As Safe (GRAS) status in the US.
• For medicinal use and when used in larger amounts, there is insufficient reliable information available about its safety, so caution is advised.
• During pregnancy and lactation, it is likely safe when consumed in amounts commonly found in foods, but larger medicinal amounts should be avoided due to limited safety data.

How Is Allspice Thought To Work? What Is the Mechanism of Action?

• Allspice is derived from the unripe fruit (berries) and leaves of the allspice tree native to Central America, southern Mexico, and the Caribbean.
• Its aromatic properties stem from compounds like eugenol, which also contribute to its traditional uses as an analgesic and antiseptic.
• Allspice contains various phenolic compounds, galloylglucosides, and tannins, which may contribute to its health effects.
• Preliminary research indicates that allspice may have potential anticancer effects due to antimutagenic and anti-proliferative properties.
• It also exhibits antimicrobial effects against various bacteria and fungi, and it may have hormonal and hypotensive effects in specific laboratory settings.
• However, further research is needed to fully understand its mechanisms of action and therapeutic potential.

Pharmacokinetics

• There is insufficient reliable information available about the pharmacokinetics of allspice.

Interaction Overview

• Allspice may interact with anticoagulant/antiplatelet drugs and supplements, potentially increasing the risk of bleeding.

Common Side Effects To Watch For

• Orally, allspice is generally well tolerated when consumed in the amounts typically found in foods.
• Adverse effects when used in larger amounts as medicine have limited data, and a thorough safety evaluation has not been conducted.

What Is Allspice Typically Used For?

• Allspice is used as a popular spice, combining the flavors of cloves, cinnamon, and nutmeg.
• Traditional medicine has utilized allspice for various purposes, including gastrointestinal ailments, fevers, colds, and as a purgative and antiseptic.
• Its essential oil contains eugenol, which might explain its use for toothache and muscle pain.
• It is valued for its potential anticancer effects, antimicrobial properties, and possible hormonal and hypotensive effects in specific contexts.
• However, more research is needed to determine its effectiveness for specific health conditions.

Commercial Products That Contain Allspice

Below is a list of known supplements that contain allspice:

Please note that this may not be a complete list of all commercially available dietary supplements that contain allspice.

All of the supplement products listed above contain allspice and therefore may interact with the drugs listed in the below section, such as:

• Plavix

See the full list in the section 'Drugs that interact with allspice'.

Drugs that interact with Allspice