Mommy's Bliss Gripe Water - Pradaxa (dabigatran) Interaction

Interaction Details

dabigatran is classified as belonging to the following category: Anticoagulant/Antiplatelet Drugs

Mommy's Bliss Gripe Water contains fennel seed and ginger. Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs as animal research suggests that fennel oil has antithrombotic and antiplatelet effects. Ginger is also thought to have mild blood-thinning effects but this has not been demonstrated conclusively in humans, with mixed results from clinical trials. It is important to note that Mommy's Bliss Gripe Water contains only very small quantities of fennel seed and ginger, and clinically significant interactions with blood-thinning drugs are thought to be quite low.

Interaction Rating

Likelihood of Occurrence

Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Pharmacist Analysis

Depending on the dose of Mommy's Bliss Gripe Water given (which depends on age), the amount of ginger and fennel seed ingested by the infant will be between 1mg and 5mg of both.

This small amount is very unlikely to cause a clinically significant interaction with any other drug that thins the blood, but it is important to be aware of it regardless.

References

• Effect of onion and ginger consumption on platelet thromboxane production in humans. PubMed
• The use of ginger (Zingiber officinale Rosc.) as a potential anti-inflammatory and antithrombotic agent. PubMed
• [Oral anticoagulants and medicinal plants. An emerging interaction]. PubMed
• Protective effect of Foeniculum vulgare essential oil and anethole in an experimental model of thrombosis. PubMed
  

dabigatran Overview

• Dabigatran is used to treat deep vein thrombosis (DVT; a blood clot, usually in the leg) and pulmonary embolism (PE; a blood clot in the lung) in adults and children 3 months of age and older who have been treated with an injectable anticoagulant ('blood thinner'). It is also used to reduce the risk of a DVT and PE from happening again after initial treatment is completed in adults and children 3 months of age and older. Dabigatran is used to help prevent DVT and PE in adults who have had hip replacement surgery. Dabigatran is also used to help prevent strokes or serious blood clots in adults who have atrial fibrillation (a condition in which the heart beats irregularly, increasing the chance of clots forming in the body, and possibly causing strokes) without heart valve disease. Dabigatran is in a class of anticoagulant medications called direct thrombin inhibitors. It works by preventing blood clots from forming in the body.

Mommy's Bliss Gripe Water - More Interactions

Mommy's Bliss Gripe Water interacts with 765 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.