Mommy's Bliss Gripe Water - Advil (Ibuprofen) Interaction

Interaction Details

Ibuprofen is classified as belonging to the following category: Anticoagulant/Antiplatelet Drugs

Mommy's Bliss Gripe Water contains fennel seed and ginger. Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs as animal research suggests that fennel oil has antithrombotic and antiplatelet effects. Ginger is also thought to have mild blood-thinning effects but this has not been demonstrated conclusively in humans, with mixed results from clinical trials. It is important to note that Mommy's Bliss Gripe Water contains only very small quantities of fennel seed and ginger, and clinically significant interactions with blood-thinning drugs are thought to be quite low.

Interaction Rating

Likelihood of Occurrence

Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Pharmacist Analysis

Depending on the dose of Mommy's Bliss Gripe Water given (which depends on age), the amount of ginger and fennel seed ingested by the infant will be between 1mg and 5mg of both.

This small amount is very unlikely to cause a clinically significant interaction with any other drug that thins the blood, but it is important to be aware of it regardless.

References

• Effect of onion and ginger consumption on platelet thromboxane production in humans. PubMed
• The use of ginger (Zingiber officinale Rosc.) as a potential anti-inflammatory and antithrombotic agent. PubMed
• [Oral anticoagulants and medicinal plants. An emerging interaction]. PubMed
• Protective effect of Foeniculum vulgare essential oil and anethole in an experimental model of thrombosis. PubMed
  

Safe With Ibuprofen?

This interaction shows simply due to the fact that Advil (ibuprofen) has very mild blood-thinning effects, but this is really only a concern in those who are already at a high risk of bleeding or are taking blood-thinning drugs (such as Coumadin and Plavix).

While fennel and ginger, two ingredients in Mommy's Bliss, have been linked to having mild blood-thinning effects, the risk of any clinically significant interaction with Advil is extremely unlikely. Add in the fact that the amounts of fennel and ginger in the product are low, there doesn't appear to be a serious risk here.

Unless your infant is already at risk of bleeding problems, Advil is likely safe to take with Mommy's Bliss Gripe Water. However, if you are concerned, Tylenol (acetaminophen) is an option for you and doesn't have a bleeding risk associated with it.

Ibuprofen Overview

• Prescription ibuprofen is used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints) and rheumatoid arthritis (arthritis caused by swelling of the lining of the joints). It is also used to relieve mild to moderate pain, including menstrual pain (pain that happens before or during a menstrual period). Nonprescription ibuprofen is used to reduce fever and to relieve minor aches and pain from headaches, muscle aches, arthritis, menstrual periods, the common cold, toothaches, and backaches. Ibuprofen is in a class of medications called NSAIDs. It works by stopping the body's production of a substance that causes pain, fever, and inflammation.

Mommy's Bliss Gripe Water - More Interactions

Mommy's Bliss Gripe Water interacts with 765 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.