Interaction Details

There were no interactions found between Estramustine Phosphate Sodium and Nattokinase. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.


Still looking for more information about combining Estramustine Phosphate Sodium and Nattokinase? Ask Dr. Brian Staiger about it by contacting him directly.

Nattokinase Overview

Nattokinase Nattokinase is an enzyme extracted from a traditional Japanese food called nattō, which is made by fermenting soybeans with the bacteria Bacillus subtilis. Nattokinase is purported to have a number of health benefits, including the ability to reduce the risk of blood clots and improve cardiovascular health. It is thought to work by breaking down proteins called fibrins, which can help to dissolve blood clot and restore normal blood flow. Some studies have suggested that nattokinase may be effective at reducing the risk of blood clots and improving cardiovascular health, although more research is needed.
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Estramustine Phosphate Sodium Overview

  • Estramustine is used to treat prostate cancer that has worsened or has spread to other parts of the body. Estramustine is in a class of medications called antimicrotubule agents. It works by stopping the growth and spread of cancer cells.

See More Information Regarding Estramustine

Nattokinase - More Interactions

Nattokinase interacts with 283 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

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Dr. Brian Staiger, PharmD

In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

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