Olive Oil - Corzide (Bendroflumethiazide, Nadolol) Interaction

Interaction Details

Bendroflumethiazide, Nadolol is classified as belonging to the following category: Antihypertensive Drugs

Theoretically, taking olive oil with antihypertensive drugs might have additive effects on blood pressure.
Some clinical and observational research suggests that adding olive oil into the diet, especially in place of saturated fat, is associated with reduced blood pressure.

Interaction Rating

Likelihood of Occurrence

Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.

Pharmacist Analysis

There are some indications that consuming olive oil with antihypertensive medication may have an additive effect on lowering blood pressure.

Clinical and observational research has shown that adding olive oil to the diet, especially in place of saturated fats, is associated with reduced blood pressure.

In one study, the consumption of olive oil and vegetable oil was inversely associated with serum cholesterol and glucose levels and systolic blood pressure. These findings suggest that monounsaturated fats like olive oil may be associated with a lower risk of cardiovascular disease.

Another study found that death rates from all causes, including coronary heart disease, were low in populations that consumed olive oil as the main fat. Although causal relationships are not claimed, these findings suggest that the monounsaturated fatty acids found in olive oil, particularly oleic acid, may have protective effects on heart health.

While olive oil is generally not known to lower blood pressure too low (i.e., cause hypotension), it's important to monitor blood pressure levels regularly and consult with a healthcare provider if there are any concerns. It is also possible that dose adjustments may be necessary under a doctor's supervision.

References

• Trevisan M, Krogh V, Freudenheim J, et al. Consumption of olive oil, butter, and vegetable oils and coronary heart disease risk factors. The Research Group ATS-RF2 of the Italian National Research Council. JAMA 1990;263:688-92.
• Keys A, Menotti A, Karvonen MJ , et al. The diet and 15-year death rate in the seven countries study. Am J Epidemiol 1986;124:903-15.
• Ferrara LA, Raimondi AS, d'Episcopo L, et al. Olive oil and reduced need for antihypertensive medications. Arch Intern Med 2000;160:837-42.

Olive Oil - More Interactions

Olive Oil interacts with 168 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.