Herb & supplement monograph

Olive Oil Drug Interactions, Uses, Effectiveness, Safety & More

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS ·Updated July 2026

What is this page for?

First and foremost: how Olive Oil interacts with medications. The heart of this page is the interaction list — every drug Olive Oil is known to interact with, and how serious each one is.

But these pages have grown well beyond that into a full monograph — what Olive Oil is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy

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Reviewed by licensed pharmacists Sourced from Natural Medicines

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Olive Oil Drug Interactions: The Bottom Line

From the HelloPharmacist Editorial Team · Updated July 2026

Based on the available evidence, the overall risk of a clinically significant Olive Oil drug interaction appears low for most people, though anyone taking blood pressure medicine should be aware of one well-documented effect. None of the listed interactions are rated major, and every one of them involves the same single concern: medications that lower blood pressure.

Interactions deserving the most attention

The interaction that deserves real attention is with blood pressure medications. Human research shows that adding olive oil to the diet, especially in place of saturated fat, is linked with lower blood pressure, so combining it with these medicines could add to their effect. For someone whose blood pressure is carefully controlled, that extra lowering is worth knowing about, and it is the one interaction here backed by actual studies in people rather than theory.

What the rest of the list means

Although the number of interacting medications looks large, it does not mean many different risks. Every medication on the list belongs to one group, blood pressure drugs, so the long list reflects a single shared effect rather than many separate problems. The effect itself comes from olive oil's dietary influence on blood pressure, which is modest and often considered a benefit.

Check your medications against Olive Oil

Based on HelloPharmacist’s Olive Oil interaction data and reviewed under our editorial standards.

Interaction report

Drugs that interact with Olive Oil

172 medications have a known interaction with Olive Oil, graded by severity. Select any drug for the full evidence-based detail.

Don’t want to scroll the list? Just ask.

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AI summaries are generated from our Olive Oil interaction data for education only — always confirm with your pharmacist. How we use AI

2,830 drugs

AcebutololRhotral, Sectral