Methyclothiazide
Generic name: Pronounced as (meth i kloe thye' a zide)
Medical Content Reviewed By HelloPharmacist Staff
Last Revised - 08/15/2017
On this page
- Why is this medication prescribed?
- How should this medicine be used?
- Other uses for this medicine
- What special precautions should I follow?
- What special dietary instructions should I follow?
- What should I do if I forget a dose?
- What side effects can this medication cause?
- What should I know about STORAGE and DISPOSAL of this medication?
- What should I do in case of OVERDOSE?
- What OTHER INFORMATION should I know?
- Brand names of combination products
- Drug interactions
Why is this medication prescribed?
Methyclothiazide is used to treat high blood pressure. Methyclothiazide is also used to treat edema (fluid retention; excess fluid held in body tissues) caused by various medical problems, including heart, kidney, and liver disease and to treat edema caused by using certain medications including estrogen and corticosteroids. Methyclothiazide is in a class of medications called diuretics ('water pills'). It works by causing the kidneys to get rid of unneeded water and salt from the body into the urine.
High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.
How should this medicine be used?
Methyclothiazide comes as a tablet to take by mouth. It usually is taken once a day in the morning. Take methyclothiazide around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take methyclothiazide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Methyclothiazide controls high blood pressure and edema but does not cure these conditions. Continue to take methyclothiazide even if you feel well. Do not stop taking methyclothiazide without talking to your doctor.
Other uses for this medicine
Methyclothiazide may also be used to treat patients with diabetes insipidus and certain electrolyte disturbances and to prevent kidney stones in patients with high levels of calcium in their blood. Talk to your doctor about the possible risks of using this medicine for your condition.
This medicine is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking methyclothiazide,
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tell your doctor and pharmacist if you are allergic to methyclothiazide, sulfonamide medications, any other medications, or any of the ingredients in methyclothiazide tablets. Ask your pharmacist or check the patient information for a list of the ingredients.
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tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: barbiturates such as phenobarbital and secobarbital (Seconal); corticosteroids such as betamethasone (Celestone), budesonide (Entocort), cortisone (Cortone), dexamethasone (Decadron, Dexpak, Dexasone, others), fludrocortisone (Florinef), hydrocortisone (Cortef, Hydrocortone), methylprednisolone (Medrol, Meprolone, others), prednisolone (Prelone, others), prednisone (Rayos), and triamcinolone (Aristocort, Azmacort); corticotropin (ACTH, H.P., Acthar Gel); insulin and oral medications for diabetes; digoxin (Lanoxin), lithium (Lithobid), medications for high blood pressure, and nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin, others) and naproxen (Aleve, Naprosyn, others). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
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tell your doctor if you have kidney disease. Your doctor may tell you not to take methyclothiazide.
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tell your doctor if you have or have ever had asthma, diabetes, gout, high cholesterol, systemic lupus erythematosus (SLE, a chronic inflammatory condition), or liver disease.
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tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking methyclothiazide, call your doctor immediately.
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plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Methyclothiazide may make your skin sensitive to sunlight.
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you should know that methyclothiazide may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common when you first start taking methyclothiazide. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up. Alcohol can add to these side effects.
What special dietary instructions should I follow?
If your doctor prescribes a low-salt or low-sodium diet, or to eat or drink increased amounts of potassium-rich foods (e.g., bananas, prunes, raisins, and orange juice) in your diet, follow these instructions carefully.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
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Tell your doctor if any of these symptoms are severe or do not go away:
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frequent urination
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stomach pain
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upset stomach
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constipation
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diarrhea
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loss of appetite
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headache
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blurred vision
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Some side effects can be serious. If you have any of these symptoms, call your doctor immediately or seek emergency medical treatment:
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dry mouth; thirst; nausea; vomiting; weakness, tiredness; drowsiness; restlessness; confusion; muscle weakness, pain, or cramps; fast heartbeat and other signs of dehydration and electrolyte imbalance
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yellowing of the eyes and skin
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fever
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blisters or peeling skin
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difficulty breathing or swallowing
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rash
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itching
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hives
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If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I know about STORAGE and DISPOSAL of this medication?
Keep this medicine in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
What OTHER INFORMATION should I know?
Keep all appointments with your doctor and the laboratory. Your blood pressure should be checked regularly, and blood tests should be done occasionally.
Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking methyclothiazide.
Do not let anyone else take your medicine. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Drug interactions
Drug | Interaction |
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Repaglinide | Repaglinide The therapeutic efficacy of Repaglinide can be decreased when used in combination with Methyclothiazide. |
Insulin Glargine (rDNA origin) Injection | Insulin Glargine (rDNA origin) Injection The therapeutic efficacy of Insulin glargine can be decreased when used in combination with Methyclothiazide. |
Bisacodyl | Bisacodyl The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Bisacodyl. |
Calcium Carbonate | Calcium Carbonate Methyclothiazide may decrease the excretion rate of Calcium carbonate which could result in a higher serum level. |
Candesartan | Candesartan The therapeutic efficacy of Candesartan can be increased when used in combination with Methyclothiazide. |
Cilostazol | Cilostazol Methyclothiazide may increase the excretion rate of Cilostazol which could result in a lower serum level and potentially a reduction in efficacy. |
Diphenoxylate | Diphenoxylate The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Diphenoxylate. |
Estrogen and Progestin (Oral Contraceptives) | Estrogen and Progestin (Oral Contraceptives) Methyclothiazide may increase the excretion rate of Conjugated estrogens which could result in a lower serum level and potentially a reduction in efficacy. |
Fenofibrate | Fenofibrate Methyclothiazide may increase the excretion rate of Fenofibrate which could result in a lower serum level and potentially a reduction in efficacy. |
Guanfacine | Guanfacine The therapeutic efficacy of Guanfacine can be increased when used in combination with Methyclothiazide. |
Magnesium Hydroxide | Magnesium Hydroxide The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Magnesium hydroxide. |
Magnesium Oxide | Magnesium Oxide The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Magnesium oxide. |
Miglitol | Miglitol The therapeutic efficacy of Miglitol can be decreased when used in combination with Methyclothiazide. |
Mycophenolate | Mycophenolate Methyclothiazide may increase the excretion rate of Mycophenolic acid which could result in a lower serum level and potentially a reduction in efficacy. |
Olsalazine | Olsalazine The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Olsalazine. |
Paregoric | Paregoric The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Morphine. |
Penbutolol | Penbutolol The therapeutic efficacy of Acebutolol can be increased when used in combination with Methyclothiazide. |
Pentazocine | Pentazocine The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Pentazocine. |
Polyethylene glycol-electrolyte solution (PEG-ES) | Polyethylene glycol-electrolyte solution (PEG-ES) The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Polyethylene glycol. |
Potassium | Potassium Methyclothiazide may increase the excretion rate of Potassium cation which could result in a lower serum level and potentially a reduction in efficacy. |
Prednisone | Prednisone The risk or severity of electrolyte imbalance can be increased when Prednisone is combined with Methyclothiazide. |
Psyllium | Psyllium The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Plantago seed. |
Ranitidine | Ranitidine Methyclothiazide may increase the excretion rate of Ranitidine which could result in a lower serum level and potentially a reduction in efficacy. |
Reserpine | Reserpine The therapeutic efficacy of Reserpine can be increased when used in combination with Methyclothiazide. |
Rizatriptan | Rizatriptan Methyclothiazide may increase the excretion rate of Rizatriptan which could result in a lower serum level and potentially a reduction in efficacy. |
Sumatriptan | Sumatriptan Methyclothiazide may increase the excretion rate of Sumatriptan which could result in a lower serum level and potentially a reduction in efficacy. |
Tacrolimus | Tacrolimus The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Tacrolimus. |
Tizanidine | Tizanidine The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Tizanidine. |
Triamcinolone | Triamcinolone The risk or severity of electrolyte imbalance can be increased when Triamcinolone is combined with Methyclothiazide. |
Ampicillin Injection | Ampicillin Injection Methyclothiazide may increase the excretion rate of Ampicillin which could result in a lower serum level and potentially a reduction in efficacy. |
Doxycycline Injection | Doxycycline Injection Methyclothiazide may increase the excretion rate of Doxycycline which could result in a lower serum level and potentially a reduction in efficacy. |
Fluconazole Injection | Fluconazole Injection Methyclothiazide may increase the excretion rate of Fluconazole which could result in a lower serum level and potentially a reduction in efficacy. |
Hydromorphone Injection | Hydromorphone Injection The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Hydromorphone. |
Interferon Beta-1b Injection | Interferon Beta-1b Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Interferon beta-1b. |
Interferon Gamma-1b Injection | Interferon Gamma-1b Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Interferon gamma-1b. |
Levofloxacin Injection | Levofloxacin Injection Methyclothiazide may increase the excretion rate of Levofloxacin which could result in a lower serum level and potentially a reduction in efficacy. |
Meperidine Injection | Meperidine Injection The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Meperidine. |
Methylprednisolone Injection | Methylprednisolone Injection The risk or severity of electrolyte imbalance can be increased when Methylprednisolone is combined with Methyclothiazide. |
Metoclopramide Injection | Metoclopramide Injection Methyclothiazide may increase the excretion rate of Metoclopramide which could result in a lower serum level and potentially a reduction in efficacy. |
Morphine Injection | Morphine Injection The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Morphine. |
Vancomycin Injection | Vancomycin Injection Methyclothiazide may increase the excretion rate of Vancomycin which could result in a lower serum level and potentially a reduction in efficacy. |
Zidovudine Injection | Zidovudine Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Zidovudine. |
Altretamine | Altretamine Amphetamine may increase the orthostatic hypotensive activities of Methyclothiazide. |
Cyclosporine | Cyclosporine The risk or severity of renal failure can be increased when Methyclothiazide is combined with Cyclosporine. |
Enoxaparin Injection | Enoxaparin Injection The therapeutic efficacy of Enoxaparin can be decreased when used in combination with Methyclothiazide. |
Torsemide | Torsemide The therapeutic efficacy of Torasemide can be increased when used in combination with Methyclothiazide. |
Olanzapine | Olanzapine The serum concentration of Methyclothiazide can be increased when it is combined with Olanzapine. |
Dofetilide | Dofetilide The risk or severity of QTc prolongation can be increased when Methyclothiazide is combined with Dofetilide. |
Eprosartan | Eprosartan The therapeutic efficacy of Eprosartan can be increased when used in combination with Methyclothiazide. |
Meloxicam | Meloxicam The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Meloxicam. |
Oxcarbazepine | Oxcarbazepine The risk or severity of hyponatremia can be increased when Methyclothiazide is combined with Oxcarbazepine. |
Pantoprazole | Pantoprazole Methyclothiazide may increase the excretion rate of Pantoprazole which could result in a lower serum level and potentially a reduction in efficacy. |
Sevelamer | Sevelamer Sevelamer can cause a decrease in the absorption of Methyclothiazide resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Telmisartan | Telmisartan The therapeutic efficacy of Telmisartan can be increased when used in combination with Methyclothiazide. |
Temozolomide | Temozolomide Methyclothiazide may increase the excretion rate of Temozolomide which could result in a lower serum level and potentially a reduction in efficacy. |
Zaleplon | Zaleplon Methyclothiazide may increase the excretion rate of Zaleplon which could result in a lower serum level and potentially a reduction in efficacy. |
Desloratadine | Desloratadine The serum concentration of Methyclothiazide can be increased when it is combined with Desloratadine. |
Linezolid | Linezolid Linezolid may increase the orthostatic hypotensive activities of Methyclothiazide. |
Pentosan Polysulfate | Pentosan Polysulfate The therapeutic efficacy of Pentosan polysulfate can be decreased when used in combination with Methyclothiazide. |
Glycopyrrolate | Glycopyrrolate The serum concentration of Methyclothiazide can be increased when it is combined with Glycopyrronium. |
Perindopril | Perindopril The therapeutic efficacy of Perindopril can be increased when used in combination with Methyclothiazide. |
Tenofovir | Tenofovir Methyclothiazide may increase the excretion rate of Tenofovir which could result in a lower serum level and potentially a reduction in efficacy. |
Choline Magnesium Trisalicylate | Choline Magnesium Trisalicylate The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Choline magnesium trisalicylate. |
Sirolimus | Sirolimus The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Sirolimus. |
Epinephrine Injection | Epinephrine Injection The risk or severity of Cardiac Arrhythmia can be increased when Epinephrine is combined with Methyclothiazide. |
Epirubicin | Epirubicin The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Epirubicin. |
Eplerenone | Eplerenone The therapeutic efficacy of Eplerenone can be increased when used in combination with Methyclothiazide. |
Escitalopram | Escitalopram The risk or severity of hyponatremia can be increased when Escitalopram is combined with Methyclothiazide. |
Olmesartan | Olmesartan The therapeutic efficacy of Olmesartan can be increased when used in combination with Methyclothiazide. |
Zonisamide | Zonisamide Methyclothiazide may increase the excretion rate of Zonisamide which could result in a lower serum level and potentially a reduction in efficacy. |
Aripiprazole | Aripiprazole Aripiprazole may increase the hypotensive activities of Methyclothiazide. |
Atomoxetine | Atomoxetine Methyclothiazide may increase the excretion rate of Atomoxetine which could result in a lower serum level and potentially a reduction in efficacy. |
Almotriptan | Almotriptan Methyclothiazide may increase the excretion rate of Almotriptan which could result in a lower serum level and potentially a reduction in efficacy. |
Polyethylene Glycol 3350 | Polyethylene Glycol 3350 The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Polyethylene glycol. |
Vardenafil | Vardenafil The risk or severity of hypotension can be increased when Vardenafil is combined with Methyclothiazide. |
Emtricitabine | Emtricitabine Methyclothiazide may increase the excretion rate of Emtricitabine which could result in a lower serum level and potentially a reduction in efficacy. |
Memantine | Memantine Methyclothiazide may increase the excretion rate of Memantine which could result in a lower serum level and potentially a reduction in efficacy. |
Tegaserod | Tegaserod The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Tegaserod. |
Tadalafil | Tadalafil The therapeutic efficacy of Tadalafil can be increased when used in combination with Methyclothiazide. |
Apomorphine Injection | Apomorphine Injection The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Apomorphine. |
Duloxetine | Duloxetine The risk or severity of orthostatic hypotension and syncope can be increased when Methyclothiazide is combined with Duloxetine. |
Tinidazole | Tinidazole Methyclothiazide may increase the excretion rate of Tinidazole which could result in a lower serum level and potentially a reduction in efficacy. |
Trospium | Trospium The serum concentration of Methyclothiazide can be increased when it is combined with Trospium. |
Bosentan | Bosentan The therapeutic efficacy of Bosentan can be increased when used in combination with Methyclothiazide. |
Cefditoren | Cefditoren Methyclothiazide may increase the excretion rate of Cefdinir which could result in a lower serum level and potentially a reduction in efficacy. |
Cyanocobalamin Injection | Cyanocobalamin Injection Methyclothiazide may increase the excretion rate of Hydroxocobalamin which could result in a lower serum level and potentially a reduction in efficacy. |
Eszopiclone | Eszopiclone Methyclothiazide may increase the excretion rate of Eszopiclone which could result in a lower serum level and potentially a reduction in efficacy. |
Ganciclovir | Ganciclovir Methyclothiazide may increase the excretion rate of Ganciclovir which could result in a lower serum level and potentially a reduction in efficacy. |
Insulin Aspart (rDNA Origin) Injection | Insulin Aspart (rDNA Origin) Injection The therapeutic efficacy of Insulin aspart can be decreased when used in combination with Methyclothiazide. |
Ribavirin | Ribavirin Methyclothiazide may increase the excretion rate of Ribavirin which could result in a lower serum level and potentially a reduction in efficacy. |
Solifenacin | Solifenacin The serum concentration of Methyclothiazide can be increased when it is combined with Solifenacin. |
Valganciclovir | Valganciclovir Methyclothiazide may increase the excretion rate of Valganciclovir which could result in a lower serum level and potentially a reduction in efficacy. |
Dextroamphetamine | Dextroamphetamine Amphetamine may increase the orthostatic hypotensive activities of Methyclothiazide. |
Peginterferon Alfa-2a Injection | Peginterferon Alfa-2a Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Peginterferon alfa-2a. |
Peginterferon Alfa-2b (PEG-Intron) | Peginterferon Alfa-2b (PEG-Intron) The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Peginterferon alfa-2b. |
Pramlintide Injection | Pramlintide Injection The therapeutic efficacy of Pramlintide can be decreased when used in combination with Methyclothiazide. |
Exenatide Injection | Exenatide Injection The therapeutic efficacy of Exenatide can be decreased when used in combination with Methyclothiazide. |
Isocarboxazid | Isocarboxazid Isocarboxazid may increase the orthostatic hypotensive activities of Methyclothiazide. |
Ramelteon | Ramelteon Methyclothiazide may increase the excretion rate of Ramelteon which could result in a lower serum level and potentially a reduction in efficacy. |
Darifenacin | Darifenacin The serum concentration of Methyclothiazide can be increased when it is combined with Darifenacin. |
Fentanyl | Fentanyl The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Fentanyl. |
Pregabalin | Pregabalin Methyclothiazide may increase the excretion rate of Pregabalin which could result in a lower serum level and potentially a reduction in efficacy. |
Insulin Detemir (rDNA Origin) Injection | Insulin Detemir (rDNA Origin) Injection The therapeutic efficacy of Insulin detemir can be decreased when used in combination with Methyclothiazide. |
Ranolazine | Ranolazine Methyclothiazide may increase the excretion rate of Ranolazine which could result in a lower serum level and potentially a reduction in efficacy. |
Rasagiline | Rasagiline Rasagiline may increase the orthostatic hypotensive activities of Methyclothiazide. |
Imatinib | Imatinib The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Imatinib. |
Sitagliptin | Sitagliptin The therapeutic efficacy of Sitagliptin can be decreased when used in combination with Methyclothiazide. |
Varenicline | Varenicline Methyclothiazide may increase the excretion rate of Varenicline which could result in a lower serum level and potentially a reduction in efficacy. |
Albuterol | Albuterol Salbutamol may increase the excretion rate of Methyclothiazide which could result in a lower serum level and potentially a reduction in efficacy. |
Paliperidone | Paliperidone Methyclothiazide may increase the excretion rate of Paliperidone which could result in a lower serum level and potentially a reduction in efficacy. |
Bortezomib | Bortezomib The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Bortezomib. |
Clofarabine Injection | Clofarabine Injection Methyclothiazide may increase the excretion rate of Clofarabine which could result in a lower serum level and potentially a reduction in efficacy. |
Insulin Glulisine (rDNA origin) Injection | Insulin Glulisine (rDNA origin) Injection The therapeutic efficacy of Insulin glulisine can be decreased when used in combination with Methyclothiazide. |
Lubiprostone | Lubiprostone The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Lubiprostone. |
Oxaliplatin Injection | Oxaliplatin Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Oxaliplatin. |
Rituximab Injection | Rituximab Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Rituximab. |
Aliskiren | Aliskiren The therapeutic efficacy of Aliskiren can be increased when used in combination with Methyclothiazide. |
Pemetrexed Injection | Pemetrexed Injection Methyclothiazide may increase the excretion rate of Pemetrexed which could result in a lower serum level and potentially a reduction in efficacy. |
Nabilone | Nabilone The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Nabilone. |
Vorinostat | Vorinostat The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Vorinostat. |
Sorafenib | Sorafenib Methyclothiazide may increase the excretion rate of Sorafenib which could result in a lower serum level and potentially a reduction in efficacy. |
Sunitinib | Sunitinib The therapeutic efficacy of Sunitinib can be decreased when used in combination with Methyclothiazide. |
Levocetirizine | Levocetirizine Methyclothiazide may increase the excretion rate of Levocetirizine which could result in a lower serum level and potentially a reduction in efficacy. |
Pegaptanib Injection | Pegaptanib Injection Methyclothiazide may increase the excretion rate of Pegaptanib which could result in a lower serum level and potentially a reduction in efficacy. |
Dasatinib | Dasatinib The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Dasatinib. |
Azacitidine Injection | Azacitidine Injection Methyclothiazide may increase the excretion rate of Azacitidine which could result in a lower serum level and potentially a reduction in efficacy. |
Paclitaxel (with polyoxyethylated castor oil) Injection | Paclitaxel (with polyoxyethylated castor oil) Injection The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Castor oil. |
Temsirolimus | Temsirolimus The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Temsirolimus. |
Nelarabine Injection | Nelarabine Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Nelarabine. |
Lenalidomide | Lenalidomide Methyclothiazide may increase the excretion rate of Lenalidomide which could result in a lower serum level and potentially a reduction in efficacy. |
Nilotinib | Nilotinib The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Nilotinib. |
Toremifene | Toremifene The risk or severity of hypercalcemia can be increased when Methyclothiazide is combined with Toremifene. |
Bexarotene | Bexarotene The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Bexarotene. |
Budesonide | Budesonide The risk or severity of electrolyte imbalance can be increased when Budesonide is combined with Methyclothiazide. |
Chloramphenicol Injection | Chloramphenicol Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Chloramphenicol. |
Decitabine Injection | Decitabine Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Decitabine. |
Desmopressin | Desmopressin Methyclothiazide may increase the excretion rate of Desmopressin which could result in a lower serum level and potentially a reduction in efficacy. |
Doripenem Injection | Doripenem Injection Methyclothiazide may increase the excretion rate of Doripenem which could result in a lower serum level and potentially a reduction in efficacy. |
Arsenic Trioxide Injection | Arsenic Trioxide Injection Methyclothiazide may increase the excretion rate of Arsenic trioxide which could result in a lower serum level and potentially a reduction in efficacy. |
Mitoxantrone Injection | Mitoxantrone Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Mitoxantrone. |
Desvenlafaxine | Desvenlafaxine The risk or severity of hyponatremia can be increased when Desvenlafaxine is combined with Methyclothiazide. |
Cevimeline | Cevimeline Methyclothiazide may increase the excretion rate of Cevimeline which could result in a lower serum level and potentially a reduction in efficacy. |
Nebivolol | Nebivolol The therapeutic efficacy of Nebivolol can be increased when used in combination with Methyclothiazide. |
Tretinoin | Tretinoin The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Tretinoin. |
Bendamustine Injection | Bendamustine Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Bendamustine. |
Certolizumab Injection | Certolizumab Injection Methyclothiazide may increase the excretion rate of Certolizumab pegol which could result in a lower serum level and potentially a reduction in efficacy. |
Ixabepilone Injection | Ixabepilone Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Ixabepilone. |
Irinotecan Injection | Irinotecan Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Irinotecan. |
Daptomycin Injection | Daptomycin Injection Methyclothiazide may increase the excretion rate of Daptomycin which could result in a lower serum level and potentially a reduction in efficacy. |
Methylnaltrexone Injection | Methylnaltrexone Injection Methyclothiazide may increase the excretion rate of Methylnaltrexone which could result in a lower serum level and potentially a reduction in efficacy. |
Alemtuzumab Injection (Chronic Lymphocytic Leukemia) | Alemtuzumab Injection (Chronic Lymphocytic Leukemia) The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Alemtuzumab. |
Midazolam | Midazolam Methyclothiazide may increase the excretion rate of Midazolam which could result in a lower serum level and potentially a reduction in efficacy. |
Naltrexone Injection | Naltrexone Injection The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Naltrexone. |
Dexrazoxane Injection | Dexrazoxane Injection Methyclothiazide may increase the excretion rate of Dexrazoxane which could result in a lower serum level and potentially a reduction in efficacy. |
Ibritumomab Injection | Ibritumomab Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Ibritumomab tiuxetan. |
Milnacipran | Milnacipran The risk or severity of hyponatremia can be increased when Milnacipran is combined with Methyclothiazide. |
Plerixafor Injection | Plerixafor Injection Methyclothiazide may increase the excretion rate of Plerixafor which could result in a lower serum level and potentially a reduction in efficacy. |
Sodium Phosphate | Sodium Phosphate Methyclothiazide may increase the nephrotoxic activities of Sodium phosphate, monobasic. |
Febuxostat | Febuxostat The therapeutic efficacy of Febuxostat can be decreased when used in combination with Methyclothiazide. |
Fesoterodine | Fesoterodine Fesoterodine may increase the excretion rate of Methyclothiazide which could result in a lower serum level and potentially a reduction in efficacy. |
Betaxolol | Betaxolol The therapeutic efficacy of Betaxolol can be increased when used in combination with Methyclothiazide. |
Prasugrel | Prasugrel Methyclothiazide may increase the excretion rate of Prasugrel which could result in a lower serum level and potentially a reduction in efficacy. |
Everolimus | Everolimus The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Everolimus. |
Pralatrexate Injection | Pralatrexate Injection Methyclothiazide may increase the excretion rate of Pralatrexate which could result in a lower serum level and potentially a reduction in efficacy. |
Palonosetron Injection | Palonosetron Injection Methyclothiazide may increase the excretion rate of Palonosetron which could result in a lower serum level and potentially a reduction in efficacy. |
Saxagliptin | Saxagliptin The therapeutic efficacy of Saxagliptin can be decreased when used in combination with Methyclothiazide. |
Telavancin Injection | Telavancin Injection Methyclothiazide may increase the excretion rate of Telavancin which could result in a lower serum level and potentially a reduction in efficacy. |
Tapentadol | Tapentadol The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Tapentadol. |
Topotecan | Topotecan Methyclothiazide may increase the excretion rate of Topotecan which could result in a lower serum level and potentially a reduction in efficacy. |
Rasburicase Injection | Rasburicase Injection The therapeutic efficacy of Rasburicase can be decreased when used in combination with Methyclothiazide. |
Oxymorphone | Oxymorphone The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Oxymorphone. |
Dabigatran | Dabigatran The therapeutic efficacy of Dabigatran can be decreased when used in combination with Methyclothiazide. |
Liraglutide Injection | Liraglutide Injection The therapeutic efficacy of Liraglutide can be decreased when used in combination with Methyclothiazide. |
Dalfampridine | Dalfampridine Methyclothiazide may increase the excretion rate of Dalfampridine which could result in a lower serum level and potentially a reduction in efficacy. |
Eribulin Injection | Eribulin Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Eribulin. |
Cabazitaxel Injection | Cabazitaxel Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Cabazitaxel. |
Pegloticase Injection | Pegloticase Injection The therapeutic efficacy of Pegloticase can be decreased when used in combination with Methyclothiazide. |
Acetaminophen Injection | Acetaminophen Injection Methyclothiazide may increase the excretion rate of Acetaminophen which could result in a lower serum level and potentially a reduction in efficacy. |
Ipilimumab Injection | Ipilimumab Injection Methyclothiazide may increase the excretion rate of Ipilimumab which could result in a lower serum level and potentially a reduction in efficacy. |
Denileukin Diftitox Injection | Denileukin Diftitox Injection Aldesleukin may increase the excretion rate of Methyclothiazide which could result in a lower serum level and potentially a reduction in efficacy. |
Terbutaline Injection | Terbutaline Injection Terbutaline may increase the excretion rate of Methyclothiazide which could result in a lower serum level and potentially a reduction in efficacy. |
Azilsartan | Azilsartan Methyclothiazide may increase the hypotensive and Electrolyte Disturbance activities of Azilsartan medoxomil. |
Busulfan Injection | Busulfan Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Busulfan. |
Roflumilast | Roflumilast Methyclothiazide may increase the excretion rate of Roflumilast which could result in a lower serum level and potentially a reduction in efficacy. |
Linagliptin | Linagliptin The therapeutic efficacy of Linagliptin can be decreased when used in combination with Methyclothiazide. |
Cyclophosphamide Injection | Cyclophosphamide Injection The risk or severity of granulocytopenia can be increased when Methyclothiazide is combined with Cyclophosphamide. |
Rivaroxaban | Rivaroxaban Methyclothiazide may increase the excretion rate of Rivaroxaban which could result in a lower serum level and potentially a reduction in efficacy. |
Ticagrelor | Ticagrelor The therapeutic efficacy of Ticagrelor can be decreased when used in combination with Methyclothiazide. |
Ruxolitinib | Ruxolitinib Methyclothiazide may increase the excretion rate of Ruxolitinib which could result in a lower serum level and potentially a reduction in efficacy. |
Clobazam | Clobazam Methyclothiazide may increase the excretion rate of Clobazam which could result in a lower serum level and potentially a reduction in efficacy. |
Deferiprone | Deferiprone Methyclothiazide may increase the excretion rate of Deferiprone which could result in a lower serum level and potentially a reduction in efficacy. |
Melphalan Injection | Melphalan Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Melphalan. |
Naloxone Injection | Naloxone Injection Naloxone may increase the excretion rate of Methyclothiazide which could result in a lower serum level and potentially a reduction in efficacy. |
Ambrisentan | Ambrisentan The therapeutic efficacy of Ambrisentan can be increased when used in combination with Methyclothiazide. |
Fondaparinux Injection | Fondaparinux Injection Methyclothiazide may increase the excretion rate of Fondaparinux which could result in a lower serum level and potentially a reduction in efficacy. |
Carfilzomib Injection | Carfilzomib Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Carfilzomib. |
Iloprost | Iloprost The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Iloprost. |
Enzalutamide | Enzalutamide Methyclothiazide may increase the excretion rate of Enzalutamide which could result in a lower serum level and potentially a reduction in efficacy. |
Mirabegron | Mirabegron Methyclothiazide may increase the excretion rate of Mirabegron which could result in a lower serum level and potentially a reduction in efficacy. |
Bosutinib | Bosutinib The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Bosutinib. |
Corticotropin, Repository Injection | Corticotropin, Repository Injection The risk or severity of electrolyte imbalance can be increased when Corticotropin is combined with Methyclothiazide. |
Linaclotide | Linaclotide The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Linaclotide. |
Lorcaserin | Lorcaserin The therapeutic efficacy of Mecasermin can be decreased when used in combination with Methyclothiazide. |
Teduglutide Injection | Teduglutide Injection Methyclothiazide may increase the excretion rate of Teduglutide which could result in a lower serum level and potentially a reduction in efficacy. |
Tofacitinib | Tofacitinib The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Tofacitinib. |
Alogliptin | Alogliptin The therapeutic efficacy of Alogliptin can be decreased when used in combination with Methyclothiazide. |
Ponatinib | Ponatinib The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Ponatinib. |
Pomalidomide | Pomalidomide Methyclothiazide may increase the excretion rate of Pomalidomide which could result in a lower serum level and potentially a reduction in efficacy. |
Ado-trastuzumab Emtansine Injection | Ado-trastuzumab Emtansine Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Trastuzumab emtansine. |
Apixaban | Apixaban The therapeutic efficacy of Apixaban can be decreased when used in combination with Methyclothiazide. |
Canagliflozin | Canagliflozin The therapeutic efficacy of Canagliflozin can be decreased when used in combination with Methyclothiazide. |
Methazolamide | Methazolamide The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Methazolamide. |
Trametinib | Trametinib Methyclothiazide may increase the excretion rate of Trametinib which could result in a lower serum level and potentially a reduction in efficacy. |
Levomilnacipran | Levomilnacipran The risk or severity of hyponatremia can be increased when Levomilnacipran is combined with Methyclothiazide. |
Ertapenem Injection | Ertapenem Injection Methyclothiazide may increase the excretion rate of Ertapenem which could result in a lower serum level and potentially a reduction in efficacy. |
Vortioxetine | Vortioxetine Methyclothiazide may increase the excretion rate of Vortioxetine which could result in a lower serum level and potentially a reduction in efficacy. |
Ibrutinib | Ibrutinib The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Ibrutinib. |
Avanafil | Avanafil The risk or severity of hypotension can be increased when Avanafil is combined with Methyclothiazide. |
Ketorolac Injection | Ketorolac Injection The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Ketorolac. |
Obinutuzumab Injection | Obinutuzumab Injection The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Obinutuzumab. |
Sofosbuvir | Sofosbuvir Methyclothiazide may increase the excretion rate of Sofosbuvir which could result in a lower serum level and potentially a reduction in efficacy. |
Dapagliflozin | Dapagliflozin The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Methyclothiazide. |
Apremilast | Apremilast Methyclothiazide may increase the excretion rate of Apremilast which could result in a lower serum level and potentially a reduction in efficacy. |
Droxidopa | Droxidopa The risk or severity of Cardiac Arrhythmia can be increased when Droxidopa is combined with Methyclothiazide. |
Albiglutide Injection | Albiglutide Injection The therapeutic efficacy of Albiglutide can be decreased when used in combination with Methyclothiazide. |
Belinostat Injection | Belinostat Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Belinostat. |
Testosterone Injection | Testosterone Injection Methyclothiazide may increase the excretion rate of Testosterone which could result in a lower serum level and potentially a reduction in efficacy. |
Empagliflozin | Empagliflozin Methyclothiazide may increase the diuretic activities of Empagliflozin. |
Vorapaxar | Vorapaxar The therapeutic efficacy of Vorapaxar can be decreased when used in combination with Methyclothiazide. |
Hydrocodone | Hydrocodone The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Hydrocodone. |
Dulaglutide Injection | Dulaglutide Injection The therapeutic efficacy of Dulaglutide can be decreased when used in combination with Methyclothiazide. |
Edoxaban | Edoxaban Methyclothiazide may increase the excretion rate of Edoxaban which could result in a lower serum level and potentially a reduction in efficacy. |
Peginterferon Beta-1a Injection | Peginterferon Beta-1a Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Peginterferon beta-1a. |
Olaparib | Olaparib The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Olaparib. |
Blinatumomab Injection | Blinatumomab Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Blinatumomab. |
Methamphetamine | Methamphetamine Methyclothiazide may increase the excretion rate of Metamfetamine which could result in a lower serum level and potentially a reduction in efficacy. |
Tasimelteon | Tasimelteon Methyclothiazide may increase the excretion rate of Tasimelteon which could result in a lower serum level and potentially a reduction in efficacy. |
Riociguat | Riociguat The therapeutic efficacy of Riociguat can be increased when used in combination with Methyclothiazide. |
Risperidone Injection | Risperidone Injection Methyclothiazide may increase the hypotensive activities of Risperidone. |
Palbociclib | Palbociclib The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Palbociclib. |
Insulin Human Inhalation | Insulin Human Inhalation The therapeutic efficacy of Insulin human can be decreased when used in combination with Methyclothiazide. |
Dinutuximab Injection | Dinutuximab Injection The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Dinutuximab. |
Haloperidol Injection | Haloperidol Injection Methyclothiazide may increase the excretion rate of Haloperidol which could result in a lower serum level and potentially a reduction in efficacy. |
Ivabradine | Ivabradine The risk or severity of Cardiac Arrhythmia can be increased when Methyclothiazide is combined with Ivabradine. |
Amiloride | Amiloride The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Amiloride. |
Macitentan | Macitentan The therapeutic efficacy of Macitentan can be increased when used in combination with Methyclothiazide. |
Prednisolone | Prednisolone The risk or severity of electrolyte imbalance can be increased when Prednisolone is combined with Methyclothiazide. |
Ziprasidone Injection | Ziprasidone Injection The serum concentration of Methyclothiazide can be increased when it is combined with Ziprasidone. |
Penicillin G Procaine Injection | Penicillin G Procaine Injection Methyclothiazide may increase the excretion rate of Procaine benzylpenicillin which could result in a lower serum level and potentially a reduction in efficacy. |
Eluxadoline | Eluxadoline The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Eluxadoline. |
Insulin Degludec (rDNA Origin) Injection | Insulin Degludec (rDNA Origin) Injection The therapeutic efficacy of Insulin degludec can be decreased when used in combination with Methyclothiazide. |
Trabectedin Injection | Trabectedin Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Trabectedin. |
Ixazomib | Ixazomib Methyclothiazide may increase the excretion rate of Ixazomib which could result in a lower serum level and potentially a reduction in efficacy. |
Lesinurad | Lesinurad The therapeutic efficacy of Lesinurad can be decreased when used in combination with Methyclothiazide. |
Amphotericin B Liposomal Injection | Amphotericin B Liposomal Injection The risk or severity of electrolyte imbalance can be increased when Methyclothiazide is combined with Amphotericin B. |
Dexamethasone Injection | Dexamethasone Injection The risk or severity of electrolyte imbalance can be increased when Dexamethasone is combined with Methyclothiazide. |
Defibrotide Injection | Defibrotide Injection The therapeutic efficacy of Defibrotide can be decreased when used in combination with Methyclothiazide. |
Brivaracetam Injection | Brivaracetam Injection Methyclothiazide may increase the excretion rate of Brivaracetam which could result in a lower serum level and potentially a reduction in efficacy. |
Selexipag | Selexipag The therapeutic efficacy of Selexipag can be increased when used in combination with Methyclothiazide. |
Diphenhydramine Injection | Diphenhydramine Injection The serum concentration of Methyclothiazide can be increased when it is combined with Diphenhydramine. |
Calcifediol | Calcifediol The risk or severity of hypercalcemia can be increased when Methyclothiazide is combined with Calcifediol. |
Ergocalciferol | Ergocalciferol The risk or severity of hypercalcemia can be increased when Methyclothiazide is combined with Ergocalciferol. |
Doxercalciferol | Doxercalciferol The risk or severity of hypercalcemia can be increased when Methyclothiazide is combined with Doxercalciferol. |
Furosemide Injection | Furosemide Injection The therapeutic efficacy of Furosemide can be increased when used in combination with Methyclothiazide. |
Lixisenatide Injection | Lixisenatide Injection The therapeutic efficacy of Lixisenatide can be decreased when used in combination with Methyclothiazide. |
Doxepin (Insomnia) | Doxepin (Insomnia) Doxepin may increase the excretion rate of Methyclothiazide which could result in a lower serum level and potentially a reduction in efficacy. |
Plecanatide | Plecanatide The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Plecanatide. |
Deutetrabenazine | Deutetrabenazine Methyclothiazide may increase the excretion rate of Deutetrabenazine which could result in a lower serum level and potentially a reduction in efficacy. |
Valbenazine | Valbenazine Methyclothiazide may increase the excretion rate of Valbenazine which could result in a lower serum level and potentially a reduction in efficacy. |
Deflazacort | Deflazacort The risk or severity of electrolyte imbalance can be increased when Deflazacort is combined with Methyclothiazide. |
Safinamide | Safinamide Safinamide may increase the orthostatic hypotensive activities of Methyclothiazide. |
Naldemedine | Naldemedine Methyclothiazide may increase the excretion rate of Naldemedine which could result in a lower serum level and potentially a reduction in efficacy. |
Benznidazole | Benznidazole Methyclothiazide may increase the excretion rate of Benznidazole which could result in a lower serum level and potentially a reduction in efficacy. |
Delafloxacin | Delafloxacin Methyclothiazide may increase the excretion rate of Delafloxacin which could result in a lower serum level and potentially a reduction in efficacy. |
Betrixaban | Betrixaban The therapeutic efficacy of Betrixaban can be decreased when used in combination with Methyclothiazide. |
Gemtuzumab Ozogamicin Injection | Gemtuzumab Ozogamicin Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Gemtuzumab ozogamicin. |
Semaglutide Injection | Semaglutide Injection The therapeutic efficacy of Semaglutide can be decreased when used in combination with Methyclothiazide. |
Ertugliflozin | Ertugliflozin The therapeutic efficacy of Ertugliflozin can be decreased when used in combination with Methyclothiazide. |
Buprenorphine Injection | Buprenorphine Injection The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Buprenorphine. |
Apalutamide | Apalutamide Methyclothiazide may increase the excretion rate of Apalutamide which could result in a lower serum level and potentially a reduction in efficacy. |
Penicillamine | Penicillamine The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Penicillamine. |
Fostamatinib | Fostamatinib The risk or severity of hypotension can be increased when Fostamatinib is combined with Methyclothiazide. |
Baricitinib | Baricitinib Methyclothiazide may increase the excretion rate of Baricitinib which could result in a lower serum level and potentially a reduction in efficacy. |
Lofexidine | Lofexidine The therapeutic efficacy of Lofexidine can be increased when used in combination with Methyclothiazide. |
Plazomicin Injection | Plazomicin Injection Methyclothiazide may increase the excretion rate of Plazomicin which could result in a lower serum level and potentially a reduction in efficacy. |
Stiripentol | Stiripentol Methyclothiazide may increase the excretion rate of Stiripentol which could result in a lower serum level and potentially a reduction in efficacy. |
Paclitaxel (with albumin) Injection | Paclitaxel (with albumin) Injection The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Paclitaxel. |
Prucalopride | Prucalopride The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Prucalopride. |
Magnesium Citrate | Magnesium Citrate The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Magnesium citrate. |
Acyclovir Ophthalmic | Acyclovir Ophthalmic Methyclothiazide may increase the excretion rate of Acyclovir which could result in a lower serum level and potentially a reduction in efficacy. |
Cladribine | Cladribine The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Cladribine. |
Solriamfetol | Solriamfetol Methyclothiazide may increase the excretion rate of Solriamfetol which could result in a lower serum level and potentially a reduction in efficacy. |
Pitolisant | Pitolisant Methyclothiazide may increase the excretion rate of Pitolisant which could result in a lower serum level and potentially a reduction in efficacy. |
Calcium Acetate | Calcium Acetate Methyclothiazide may decrease the excretion rate of Calcium acetate which could result in a higher serum level. |
Viloxazine | Viloxazine Methyclothiazide may increase the excretion rate of Viloxazine which could result in a lower serum level and potentially a reduction in efficacy. |
Fenoprofen | Fenoprofen The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Fenoprofen. |
Indomethacin | Indomethacin The therapeutic efficacy of Indomethacin can be decreased when used in combination with Methyclothiazide. |
Mefenamic Acid | Mefenamic Acid The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Mefenamic acid. |
Naproxen | Naproxen The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Naproxen. |
Tolmetin | Tolmetin The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Tolmetin. |
Trazodone | Trazodone The risk or severity of hyponatremia can be increased when Trazodone is combined with Methyclothiazide. |
Isotretinoin | Isotretinoin Methyclothiazide may increase the excretion rate of Isotretinoin which could result in a lower serum level and potentially a reduction in efficacy. |
Sucralfate | Sucralfate Methyclothiazide may increase the excretion rate of Sucralfate which could result in a lower serum level and potentially a reduction in efficacy. |
Hydroxyurea | Hydroxyurea The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Hydroxyurea. |
Floxuridine | Floxuridine Methyclothiazide may increase the excretion rate of Floxuridine which could result in a lower serum level and potentially a reduction in efficacy. |
Phenobarbital | Phenobarbital The risk or severity of hypotension and orthostatic hypotension can be increased when Phenobarbital is combined with Methyclothiazide. |
Metaxalone | Metaxalone Methyclothiazide may increase the excretion rate of Metaxalone which could result in a lower serum level and potentially a reduction in efficacy. |
Methotrexate Injection | Methotrexate Injection The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Methotrexate. |
Levorphanol | Levorphanol The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Levorphanol. |
Primidone | Primidone The risk or severity of hypotension and orthostatic hypotension can be increased when Primidone is combined with Methyclothiazide. |
Chlorpromazine | Chlorpromazine Methyclothiazide may increase the excretion rate of Chlorpromazine which could result in a lower serum level and potentially a reduction in efficacy. |
Diazepam | Diazepam Methyclothiazide may increase the excretion rate of Diazepam which could result in a lower serum level and potentially a reduction in efficacy. |
Oxazepam | Oxazepam Methyclothiazide may increase the excretion rate of Oxazepam which could result in a lower serum level and potentially a reduction in efficacy. |
Flurazepam | Flurazepam Methyclothiazide may increase the excretion rate of Flurazepam which could result in a lower serum level and potentially a reduction in efficacy. |
Clorazepate | Clorazepate Methyclothiazide may increase the excretion rate of Clorazepic acid which could result in a lower serum level and potentially a reduction in efficacy. |
Lorazepam | Lorazepam Methyclothiazide may increase the excretion rate of Lorazepam which could result in a lower serum level and potentially a reduction in efficacy. |
Phenoxybenzamine | Phenoxybenzamine The therapeutic efficacy of Phenoxybenzamine can be increased when used in combination with Methyclothiazide. |
Carmustine | Carmustine Methyclothiazide may increase the excretion rate of Carmustine which could result in a lower serum level and potentially a reduction in efficacy. |
Amantadine | Amantadine Methyclothiazide may increase the excretion rate of Amantadine which could result in a lower serum level and potentially a reduction in efficacy. |
Codeine | Codeine The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Codeine. |
Bromocriptine | Bromocriptine The therapeutic efficacy of Bromocriptine can be decreased when used in combination with Methyclothiazide. |
Metaproterenol | Metaproterenol Orciprenaline may increase the hypokalemic activities of Methyclothiazide. |
Tranylcypromine | Tranylcypromine Tranylcypromine may increase the orthostatic hypotensive activities of Methyclothiazide. |
Phenelzine | Phenelzine Phenelzine may increase the orthostatic hypotensive activities of Methyclothiazide. |
Procarbazine | Procarbazine Procarbazine may increase the orthostatic hypotensive activities of Methyclothiazide. |
Tetracycline | Tetracycline Methyclothiazide may increase the excretion rate of Tetracycline which could result in a lower serum level and potentially a reduction in efficacy. |
Thioguanine | Thioguanine The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Tioguanine. |
Thioridazine | Thioridazine The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Thioridazine. |
Bleomycin | Bleomycin Methyclothiazide may increase the excretion rate of Bleomycin which could result in a lower serum level and potentially a reduction in efficacy. |
Sulfadiazine | Sulfadiazine The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Methyclothiazide. |
Oxycodone | Oxycodone The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Oxycodone. |
Methadone | Methadone The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Methadone. |
Oxybutynin | Oxybutynin The serum concentration of Methyclothiazide can be increased when it is combined with Oxybutynin. |
Benztropine | Benztropine Benzatropine may increase the excretion rate of Methyclothiazide which could result in a lower serum level and potentially a reduction in efficacy. |
Colestipol | Colestipol Colestipol can cause a decrease in the absorption of Methyclothiazide resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Maprotiline | Maprotiline Maprotiline may increase the excretion rate of Methyclothiazide which could result in a lower serum level and potentially a reduction in efficacy. |
Ibuprofen | Ibuprofen The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Ibuprofen. |
Trihexyphenidyl | Trihexyphenidyl The serum concentration of Methyclothiazide can be increased when it is combined with Trihexyphenidyl. |
Orphenadrine | Orphenadrine The serum concentration of Methyclothiazide can be increased when it is combined with Orphenadrine. |
Azathioprine | Azathioprine Methyclothiazide may increase the excretion rate of Azathioprine which could result in a lower serum level and potentially a reduction in efficacy. |
Methylphenidate | Methylphenidate Methyclothiazide may increase the excretion rate of Methylphenidate which could result in a lower serum level and potentially a reduction in efficacy. |
Amoxapine | Amoxapine The serum concentration of Methyclothiazide can be increased when it is combined with Amoxapine. |
Sulfasalazine | Sulfasalazine The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Sulfasalazine. |
Hydrocortisone | Hydrocortisone The risk or severity of electrolyte imbalance can be increased when Hydrocortisone is combined with Methyclothiazide. |
Lomustine | Lomustine The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Lomustine. |
Doxorubicin | Doxorubicin The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Doxorubicin. |
Cytarabine | Cytarabine The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Cytarabine. |
Mechlorethamine | Mechlorethamine The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Mechlorethamine. |
Dactinomycin | Dactinomycin The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Dactinomycin. |
Phenazopyridine | Phenazopyridine Methyclothiazide may increase the excretion rate of Phenazopyridine which could result in a lower serum level and potentially a reduction in efficacy. |
Carbamazepine | Carbamazepine The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Carbamazepine. |
Methyldopa | Methyldopa The therapeutic efficacy of Methyldopa can be increased when used in combination with Methyclothiazide. |
Clonidine | Clonidine The therapeutic efficacy of Clonidine can be increased when used in combination with Methyclothiazide. |
Prazosin | Prazosin The therapeutic efficacy of Prazosin can be increased when used in combination with Methyclothiazide. |
Hydralazine | Hydralazine The therapeutic efficacy of Hydralazine can be increased when used in combination with Methyclothiazide. |
Cimetidine | Cimetidine Methyclothiazide may increase the excretion rate of Cimetidine which could result in a lower serum level and potentially a reduction in efficacy. |
Warfarin | Warfarin Methyclothiazide may increase the excretion rate of Warfarin which could result in a lower serum level and potentially a reduction in efficacy. |
Clonazepam | Clonazepam Methyclothiazide may increase the excretion rate of Clonazepam which could result in a lower serum level and potentially a reduction in efficacy. |
Promethazine | Promethazine Promethazine may increase the excretion rate of Methyclothiazide which could result in a lower serum level and potentially a reduction in efficacy. |
Meclofenamate | Meclofenamate The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Meclofenamic acid. |
Daunorubicin | Daunorubicin The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Daunorubicin. |
Nitrofurantoin | Nitrofurantoin Methyclothiazide may increase the excretion rate of Nitrofurantoin which could result in a lower serum level and potentially a reduction in efficacy. |
Methenamine | Methenamine The therapeutic efficacy of Methenamine can be decreased when used in combination with Methyclothiazide. |
Digoxin | Digoxin Methyclothiazide may increase the hypokalemic activities of Digoxin. |
Chloroquine | Chloroquine Methyclothiazide may increase the excretion rate of Chloroquine which could result in a lower serum level and potentially a reduction in efficacy. |
Quinine | Quinine The therapeutic efficacy of Quinine can be decreased when used in combination with Methyclothiazide. |
Calcitriol | Calcitriol The risk or severity of hypercalcemia can be increased when Methyclothiazide is combined with Calcitriol. |
Triamterene | Triamterene The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Triamterene. |
Lactulose | Lactulose The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Lactulose. |
Sulfinpyrazone | Sulfinpyrazone The therapeutic efficacy of Sulfinpyrazone can be decreased when used in combination with Methyclothiazide. |
Chlorothiazide | Chlorothiazide The therapeutic efficacy of Chlorothiazide can be increased when used in combination with Methyclothiazide. |
Chlorthalidone | Chlorthalidone The therapeutic efficacy of Chlorthalidone can be increased when used in combination with Methyclothiazide. |
Metolazone | Metolazone The therapeutic efficacy of Metolazone can be increased when used in combination with Methyclothiazide. |
Secobarbital | Secobarbital The risk or severity of hypotension and orthostatic hypotension can be increased when Secobarbital is combined with Methyclothiazide. |
Desipramine | Desipramine Desipramine may increase the excretion rate of Methyclothiazide which could result in a lower serum level and potentially a reduction in efficacy. |
Amitriptyline | Amitriptyline Amitriptyline may increase the excretion rate of Methyclothiazide which could result in a lower serum level and potentially a reduction in efficacy. |
Imipramine | Imipramine Methyclothiazide may increase the excretion rate of Imipramine which could result in a lower serum level and potentially a reduction in efficacy. |
Probenecid | Probenecid The therapeutic efficacy of Probenecid can be decreased when used in combination with Methyclothiazide. |
Quinidine | Quinidine Quinidine may increase the excretion rate of Methyclothiazide which could result in a lower serum level and potentially a reduction in efficacy. |
Procainamide | Procainamide Methyclothiazide may increase the excretion rate of Procainamide which could result in a lower serum level and potentially a reduction in efficacy. |
Isoniazid | Isoniazid Methyclothiazide may increase the excretion rate of Isoniazid which could result in a lower serum level and potentially a reduction in efficacy. |
Pyrazinamide | Pyrazinamide Methyclothiazide may increase the excretion rate of Pyrazinamide which could result in a lower serum level and potentially a reduction in efficacy. |
Disopyramide | Disopyramide The therapeutic efficacy of Disopyramide can be decreased when used in combination with Methyclothiazide. |
Mitomycin | Mitomycin The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Mitomycin. |
Butabarbital | Butabarbital Methyclothiazide may increase the excretion rate of Butabarbital which could result in a lower serum level and potentially a reduction in efficacy. |
Liothyronine | Liothyronine Methyclothiazide may increase the excretion rate of Liothyronine which could result in a lower serum level and potentially a reduction in efficacy. |
Methimazole | Methimazole Methyclothiazide may increase the excretion rate of Methimazole which could result in a lower serum level and potentially a reduction in efficacy. |
Propylthiouracil | Propylthiouracil The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Propylthiouracil. |
Chlorpropamide | Chlorpropamide The therapeutic efficacy of Chlorpropamide can be decreased when used in combination with Methyclothiazide. |
Tolbutamide | Tolbutamide The therapeutic efficacy of Tolbutamide can be decreased when used in combination with Methyclothiazide. |
Tolazamide | Tolazamide The therapeutic efficacy of Tolazamide can be decreased when used in combination with Methyclothiazide. |
Dextromethorphan | Dextromethorphan The serum concentration of Methyclothiazide can be increased when it is combined with Dextromethorphan. |
Baclofen | Baclofen Methyclothiazide may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy. |
Doxylamine | Doxylamine The serum concentration of Methyclothiazide can be increased when it is combined with Doxylamine. |
Cyproheptadine | Cyproheptadine The serum concentration of Methyclothiazide can be increased when it is combined with Cyproheptadine. |
Brompheniramine | Brompheniramine The serum concentration of Methyclothiazide can be increased when it is combined with Brompheniramine. |
Ethambutol | Ethambutol Methyclothiazide may increase the excretion rate of Ethambutol which could result in a lower serum level and potentially a reduction in efficacy. |
Hydrochlorothiazide | Hydrochlorothiazide The therapeutic efficacy of Hydrochlorothiazide can be increased when used in combination with Methyclothiazide. |
Chlorzoxazone | Chlorzoxazone Methyclothiazide may increase the excretion rate of Chlorzoxazone which could result in a lower serum level and potentially a reduction in efficacy. |
Pyridoxine | Pyridoxine Methyclothiazide may increase the excretion rate of Pyridoxine which could result in a lower serum level and potentially a reduction in efficacy. |
Folic Acid | Folic Acid Methyclothiazide may increase the excretion rate of Folic acid which could result in a lower serum level and potentially a reduction in efficacy. |
Propranolol (Cardiovascular) | Propranolol (Cardiovascular) The therapeutic efficacy of Propranolol can be increased when used in combination with Methyclothiazide. |
Minoxidil | Minoxidil The therapeutic efficacy of Minoxidil can be increased when used in combination with Methyclothiazide. |
Nortriptyline | Nortriptyline The serum concentration of Methyclothiazide can be increased when it is combined with Nortriptyline. |
Spironolactone | Spironolactone The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Spironolactone. |
Amphotericin B Injection | Amphotericin B Injection The risk or severity of electrolyte imbalance can be increased when Methyclothiazide is combined with Amphotericin B. |
Mercaptopurine | Mercaptopurine The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Mercaptopurine. |
Phytonadione | Phytonadione Methyclothiazide may increase the excretion rate of Phylloquinone which could result in a lower serum level and potentially a reduction in efficacy. |
Nadolol | Nadolol The therapeutic efficacy of Nadolol can be increased when used in combination with Methyclothiazide. |
Butorphanol Injection | Butorphanol Injection The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Butorphanol. |
Nalbuphine Injection | Nalbuphine Injection The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Nalbuphine. |
Cholestyramine Resin | Cholestyramine Resin Cholestyramine can cause a decrease in the absorption of Methyclothiazide resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Allopurinol | Allopurinol The risk of a hypersensitivity reaction to Allopurinol is increased when it is combined with Methyclothiazide. |
Flavoxate | Flavoxate Flavoxate may increase the excretion rate of Methyclothiazide which could result in a lower serum level and potentially a reduction in efficacy. |
Papaverine | Papaverine The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Papaverine. |
Fluorouracil Injection | Fluorouracil Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Fluorouracil. |
Colchicine | Colchicine The therapeutic efficacy of Colchicine can be decreased when used in combination with Methyclothiazide. |
Cefaclor | Cefaclor Methyclothiazide may increase the excretion rate of Cefaclor which could result in a lower serum level and potentially a reduction in efficacy. |
Cefadroxil | Cefadroxil Methyclothiazide may increase the excretion rate of Cefadroxil which could result in a lower serum level and potentially a reduction in efficacy. |
Cephalexin | Cephalexin Methyclothiazide may increase the excretion rate of Cephalexin which could result in a lower serum level and potentially a reduction in efficacy. |
Dacarbazine | Dacarbazine Methyclothiazide may increase the excretion rate of Dacarbazine which could result in a lower serum level and potentially a reduction in efficacy. |
Calcitonin Salmon Injection | Calcitonin Salmon Injection Methyclothiazide may increase the excretion rate of Salmon calcitonin which could result in a lower serum level and potentially a reduction in efficacy. |
Pyrantel | Pyrantel Methyclothiazide may increase the excretion rate of Pyrantel which could result in a lower serum level and potentially a reduction in efficacy. |
Thiotepa Injection | Thiotepa Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Thiotepa. |
Captopril | Captopril The therapeutic efficacy of Captopril can be increased when used in combination with Methyclothiazide. |
Dipyridamole | Dipyridamole The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Dipyridamole. |
Isoxsuprine | Isoxsuprine The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Isoxsuprine. |
Vinblastine | Vinblastine The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Vinblastine. |
Ethacrynic Acid | Ethacrynic Acid The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Etacrynic acid. |
Metoprolol | Metoprolol The therapeutic efficacy of Metoprolol can be increased when used in combination with Methyclothiazide. |
Aspirin | Aspirin Acetylsalicylic acid may decrease the excretion rate of Methyclothiazide which could result in a higher serum level. |
Salsalate | Salsalate The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Salsalate. |
Chlorambucil | Chlorambucil The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Chlorambucil. |
Alprazolam | Alprazolam Methyclothiazide may increase the excretion rate of Alprazolam which could result in a lower serum level and potentially a reduction in efficacy. |
Temazepam | Temazepam Methyclothiazide may increase the excretion rate of Temazepam which could result in a lower serum level and potentially a reduction in efficacy. |
Triazolam | Triazolam Methyclothiazide may increase the excretion rate of Triazolam which could result in a lower serum level and potentially a reduction in efficacy. |
Dicyclomine | Dicyclomine Dicyclomine may increase the excretion rate of Methyclothiazide which could result in a lower serum level and potentially a reduction in efficacy. |
Hyoscyamine | Hyoscyamine The serum concentration of Methyclothiazide can be increased when it is combined with Hyoscyamine. |
Propantheline | Propantheline Propantheline may increase the excretion rate of Methyclothiazide which could result in a lower serum level and potentially a reduction in efficacy. |
Trimethoprim | Trimethoprim Methyclothiazide may increase the excretion rate of Trimethoprim which could result in a lower serum level and potentially a reduction in efficacy. |
Diltiazem | Diltiazem The therapeutic efficacy of Diltiazem can be increased when used in combination with Methyclothiazide. |
Nifedipine | Nifedipine Methyclothiazide may increase the excretion rate of Nifedipine which could result in a lower serum level and potentially a reduction in efficacy. |
Timolol | Timolol The therapeutic efficacy of Timolol can be increased when used in combination with Methyclothiazide. |
Verapamil | Verapamil Methyclothiazide may increase the excretion rate of Verapamil which could result in a lower serum level and potentially a reduction in efficacy. |
Atenolol | Atenolol The therapeutic efficacy of Atenolol can be increased when used in combination with Methyclothiazide. |
Pindolol | Pindolol The therapeutic efficacy of Pindolol can be increased when used in combination with Methyclothiazide. |
Cisplatin Injection | Cisplatin Injection Methyclothiazide may increase the excretion rate of Cisplatin which could result in a lower serum level and potentially a reduction in efficacy. |
Diflunisal | Diflunisal The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Diflunisal. |
Piroxicam | Piroxicam The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Piroxicam. |
Bumetanide | Bumetanide Methyclothiazide may increase the excretion rate of Bumetanide which could result in a lower serum level and potentially a reduction in efficacy. |
Streptozocin | Streptozocin The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Streptozocin. |
Etoposide | Etoposide The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Etoposide. |
Glyburide | Glyburide The therapeutic efficacy of Glyburide can be decreased when used in combination with Methyclothiazide. |
Glipizide | Glipizide The therapeutic efficacy of Glipizide can be decreased when used in combination with Methyclothiazide. |
Indapamide | Indapamide The therapeutic efficacy of Indapamide can be increased when used in combination with Methyclothiazide. |
Amoxicillin | Amoxicillin Methyclothiazide may increase the excretion rate of Amoxicillin which could result in a lower serum level and potentially a reduction in efficacy. |
Oxacillin Injection | Oxacillin Injection Methyclothiazide may increase the excretion rate of Oxacillin which could result in a lower serum level and potentially a reduction in efficacy. |
Pentoxifylline | Pentoxifylline Methyclothiazide may increase the excretion rate of Pentoxifylline which could result in a lower serum level and potentially a reduction in efficacy. |
Pentamidine Injection | Pentamidine Injection The therapeutic efficacy of Pentamidine can be decreased when used in combination with Methyclothiazide. |
Ceftriaxone Injection | Ceftriaxone Injection Methyclothiazide may increase the excretion rate of Ceftriaxone which could result in a lower serum level and potentially a reduction in efficacy. |
Labetalol | Labetalol The therapeutic efficacy of Labetalol can be increased when used in combination with Methyclothiazide. |
Auranofin | Auranofin Methyclothiazide may increase the excretion rate of Auranofin which could result in a lower serum level and potentially a reduction in efficacy. |
Leuprolide Injection | Leuprolide Injection Methyclothiazide may increase the excretion rate of Leuprolide which could result in a lower serum level and potentially a reduction in efficacy. |
Gemfibrozil | Gemfibrozil Methyclothiazide may increase the excretion rate of Gemfibrozil which could result in a lower serum level and potentially a reduction in efficacy. |
Guanabenz | Guanabenz The therapeutic efficacy of Guanabenz can be increased when used in combination with Methyclothiazide. |
Ceftazidime Injection | Ceftazidime Injection Methyclothiazide may increase the excretion rate of Ceftazidime which could result in a lower serum level and potentially a reduction in efficacy. |
Ketoprofen | Ketoprofen The risk or severity of adverse effects can be increased when Ketoprofen is combined with Methyclothiazide. |
Cefotetan Injection | Cefotetan Injection Methyclothiazide may increase the excretion rate of Cefotetan which could result in a lower serum level and potentially a reduction in efficacy. |
Enalapril | Enalapril The therapeutic efficacy of Enalapril can be increased when used in combination with Methyclothiazide. |
Flurbiprofen | Flurbiprofen The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Flurbiprofen. |
Amiodarone | Amiodarone The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Amiodarone. |
Aztreonam Injection | Aztreonam Injection Methyclothiazide may increase the excretion rate of Aztreonam which could result in a lower serum level and potentially a reduction in efficacy. |
Buspirone | Buspirone Methyclothiazide may increase the excretion rate of Buspirone which could result in a lower serum level and potentially a reduction in efficacy. |
Ciprofloxacin | Ciprofloxacin Methyclothiazide may increase the excretion rate of Ciprofloxacin which could result in a lower serum level and potentially a reduction in efficacy. |
Mesalamine | Mesalamine The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Mesalazine. |
Diclofenac | Diclofenac The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Diclofenac. |
Fluoxetine | Fluoxetine The risk or severity of hyponatremia can be increased when Fluoxetine is combined with Methyclothiazide. |
Nimodipine | Nimodipine The therapeutic efficacy of Nimodipine can be increased when used in combination with Methyclothiazide. |
Interferon Alfa-2b Injection | Interferon Alfa-2b Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Interferon alfa-2b. |
Clozapine | Clozapine Methyclothiazide may increase the excretion rate of Clozapine which could result in a lower serum level and potentially a reduction in efficacy. |
Estazolam | Estazolam Methyclothiazide may increase the excretion rate of Estazolam which could result in a lower serum level and potentially a reduction in efficacy. |
Idarubicin | Idarubicin The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Idarubicin. |
Didanosine | Didanosine Methyclothiazide may increase the excretion rate of Didanosine which could result in a lower serum level and potentially a reduction in efficacy. |
Fludarabine Injection | Fludarabine Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Fludarabine. |
Pentostatin Injection | Pentostatin Injection Methyclothiazide may increase the excretion rate of Pentostatin which could result in a lower serum level and potentially a reduction in efficacy. |
Benazepril | Benazepril The therapeutic efficacy of Benazepril can be increased when used in combination with Methyclothiazide. |
Etodolac | Etodolac The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Etodolac. |
Felodipine | Felodipine The therapeutic efficacy of Felodipine can be increased when used in combination with Methyclothiazide. |
Fosinopril | Fosinopril The therapeutic efficacy of Fosinopril can be increased when used in combination with Methyclothiazide. |
Nabumetone | Nabumetone The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Nabumetone. |
Quinapril | Quinapril The therapeutic efficacy of Quinapril can be increased when used in combination with Methyclothiazide. |
Ramipril | Ramipril The therapeutic efficacy of Ramipril can be increased when used in combination with Methyclothiazide. |
Amlodipine | Amlodipine The therapeutic efficacy of Amlodipine can be increased when used in combination with Methyclothiazide. |
Teniposide Injection | Teniposide Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Teniposide. |
Lisinopril | Lisinopril The therapeutic efficacy of Lisinopril can be increased when used in combination with Methyclothiazide. |
Oxaprozin | Oxaprozin The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Oxaprozin. |
Sotalol | Sotalol The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Sotalol. |
Bisoprolol | Bisoprolol The therapeutic efficacy of Bisoprolol can be increased when used in combination with Methyclothiazide. |
Doxazosin | Doxazosin The therapeutic efficacy of Doxazosin can be increased when used in combination with Methyclothiazide. |
Terazosin | Terazosin The therapeutic efficacy of Terazosin can be increased when used in combination with Methyclothiazide. |
Isradipine | Isradipine The therapeutic efficacy of Isradipine can be increased when used in combination with Methyclothiazide. |
Venlafaxine | Venlafaxine Methyclothiazide may increase the excretion rate of Venlafaxine which could result in a lower serum level and potentially a reduction in efficacy. |
Fluvoxamine | Fluvoxamine The risk or severity of hyponatremia can be increased when Fluvoxamine is combined with Methyclothiazide. |
Nefazodone | Nefazodone The risk or severity of hyponatremia can be increased when Nefazodone is combined with Methyclothiazide. |
Lamotrigine | Lamotrigine Lamotrigine may increase the excretion rate of Methyclothiazide which could result in a lower serum level and potentially a reduction in efficacy. |
Losartan | Losartan The therapeutic efficacy of Losartan can be increased when used in combination with Methyclothiazide. |
Valacyclovir | Valacyclovir Methyclothiazide may increase the excretion rate of Valaciclovir which could result in a lower serum level and potentially a reduction in efficacy. |
Tramadol | Tramadol The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Tramadol. |
Vinorelbine Injection | Vinorelbine Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Vinorelbine. |
Carboplatin Injection | Carboplatin Injection Methyclothiazide may increase the excretion rate of Carboplatin which could result in a lower serum level and potentially a reduction in efficacy. |
Moexipril | Moexipril The therapeutic efficacy of Moexipril can be increased when used in combination with Methyclothiazide. |
Ifosfamide Injection | Ifosfamide Injection Methyclothiazide may increase the excretion rate of Ifosfamide which could result in a lower serum level and potentially a reduction in efficacy. |
Nicardipine | Nicardipine The therapeutic efficacy of Nicardipine can be increased when used in combination with Methyclothiazide. |
Bupropion | Bupropion Methyclothiazide may increase the excretion rate of Bupropion which could result in a lower serum level and potentially a reduction in efficacy. |
Ticlopidine | Ticlopidine Methyclothiazide may increase the excretion rate of Ticlopidine which could result in a lower serum level and potentially a reduction in efficacy. |
Metformin | Metformin The therapeutic efficacy of Metformin can be decreased when used in combination with Methyclothiazide. |
Dalteparin Injection | Dalteparin Injection The therapeutic efficacy of Dalteparin can be decreased when used in combination with Methyclothiazide. |
Nisoldipine | Nisoldipine The therapeutic efficacy of Nisoldipine can be increased when used in combination with Methyclothiazide. |
Lamivudine | Lamivudine Methyclothiazide may increase the excretion rate of Lamivudine which could result in a lower serum level and potentially a reduction in efficacy. |
Amifostine Injection | Amifostine Injection The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Amifostine. |
Acarbose | Acarbose The therapeutic efficacy of Acarbose can be decreased when used in combination with Methyclothiazide. |
Glimepiride | Glimepiride The therapeutic efficacy of Glimepiride can be decreased when used in combination with Methyclothiazide. |
Gemcitabine Injection | Gemcitabine Injection Methyclothiazide may increase the excretion rate of Gemcitabine which could result in a lower serum level and potentially a reduction in efficacy. |
Docetaxel Injection | Docetaxel Injection The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Docetaxel. |
Cidofovir Injection | Cidofovir Injection Methyclothiazide may increase the excretion rate of Cidofovir which could result in a lower serum level and potentially a reduction in efficacy. |
Meropenem Injection | Meropenem Injection Methyclothiazide may increase the excretion rate of Meropenem which could result in a lower serum level and potentially a reduction in efficacy. |
Clomipramine | Clomipramine Methyclothiazide may increase the excretion rate of Clomipramine which could result in a lower serum level and potentially a reduction in efficacy. |
Fosfomycin | Fosfomycin Methyclothiazide may increase the excretion rate of Fosfomycin which could result in a lower serum level and potentially a reduction in efficacy. |
Trandolapril | Trandolapril The therapeutic efficacy of Trandolapril can be increased when used in combination with Methyclothiazide. |
Topiramate | Topiramate The risk or severity of hypokalemia can be increased when Methyclothiazide is combined with Topiramate. |
Valsartan | Valsartan The therapeutic efficacy of Valsartan can be increased when used in combination with Methyclothiazide. |
Insulin Lispro Injection | Insulin Lispro Injection The therapeutic efficacy of Insulin lispro can be decreased when used in combination with Methyclothiazide. |
Pramipexole | Pramipexole Methyclothiazide may increase the excretion rate of Pramipexole which could result in a lower serum level and potentially a reduction in efficacy. |
Carvedilol | Carvedilol The therapeutic efficacy of Carvedilol can be increased when used in combination with Methyclothiazide. |
Nilutamide | Nilutamide Methyclothiazide may increase the excretion rate of Nilutamide which could result in a lower serum level and potentially a reduction in efficacy. |
Flutamide | Flutamide Methyclothiazide may increase the excretion rate of Flutamide which could result in a lower serum level and potentially a reduction in efficacy. |
Selegiline | Selegiline Selegiline may increase the orthostatic hypotensive activities of Methyclothiazide. |
Sertraline | Sertraline The risk or severity of hyponatremia can be increased when Sertraline is combined with Methyclothiazide. |
Irbesartan | Irbesartan The therapeutic efficacy of Irbesartan can be increased when used in combination with Methyclothiazide. |
Tamsulosin | Tamsulosin Methyclothiazide may increase the excretion rate of Tamsulosin which could result in a lower serum level and potentially a reduction in efficacy. |
Ropinirole | Ropinirole The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Ropinirole. |
Quetiapine | Quetiapine Methyclothiazide may increase the excretion rate of Quetiapine which could result in a lower serum level and potentially a reduction in efficacy. |
Cetirizine | Cetirizine Methyclothiazide may increase the excretion rate of Cetirizine which could result in a lower serum level and potentially a reduction in efficacy. |
Paroxetine | Paroxetine The risk or severity of hyponatremia can be increased when Paroxetine is combined with Methyclothiazide. |
Tolcapone | Tolcapone Methyclothiazide may increase the excretion rate of Tolcapone which could result in a lower serum level and potentially a reduction in efficacy. |
Citalopram | Citalopram The risk or severity of hyponatremia can be increased when Citalopram is combined with Methyclothiazide. |
Capecitabine | Capecitabine Methyclothiazide may increase the excretion rate of Capecitabine which could result in a lower serum level and potentially a reduction in efficacy. |
Abacavir | Abacavir Methyclothiazide may increase the excretion rate of Abacavir which could result in a lower serum level and potentially a reduction in efficacy. |
Sildenafil | Sildenafil The risk or severity of hypotension can be increased when Sildenafil is combined with Methyclothiazide. |
Pioglitazone | Pioglitazone The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Methyclothiazide. |
Celecoxib | Celecoxib The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Celecoxib. |
Rosiglitazone | Rosiglitazone The therapeutic efficacy of Rosiglitazone can be decreased when used in combination with Methyclothiazide. |
Tolterodine | Tolterodine Tolterodine may increase the excretion rate of Methyclothiazide which could result in a lower serum level and potentially a reduction in efficacy. |
Thalidomide | Thalidomide The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Thalidomide. |
Oseltamivir | Oseltamivir Methyclothiazide may increase the excretion rate of Oseltamivir which could result in a lower serum level and potentially a reduction in efficacy. |
Colesevelam | Colesevelam Colesevelam can cause a decrease in the absorption of Methyclothiazide resulting in a reduced serum concentration and potentially a decrease in efficacy. |
Balsalazide | Balsalazide The therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Balsalazide. |
Nateglinide | Nateglinide The therapeutic efficacy of Nateglinide can be decreased when used in combination with Methyclothiazide. |
Rabeprazole | Rabeprazole Methyclothiazide may increase the excretion rate of Rabeprazole which could result in a lower serum level and potentially a reduction in efficacy. |
* This branded product is no longer on the market. Generic alternatives may be available.
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