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Methazolamide

Methazolamide is an oral carbonic anhydrase inhibitor used to lower pressure inside the eye in certain types of glaucoma.

Brand name Neptazane
Rx Form 1
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026 Content updated Oct 2, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 12 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

✓No current FDA shortage listed · checked Oct 5, 2026
Methazolamide at a glance The quick version — the full detail is in the Patient Information Guide below.
Dr. Brian Staiger, PharmD, BCPS
The Pharmacist’s Take By · Clinical pharmacist · Written

Methazolamide (Neptazane) is a glaucoma tablet that lowers eye pressure by blocking an enzyme, carbonic anhydrase, so the eye makes less fluid; it is usually an add-on when eye drops are not enough, has been on the market since about 1989, and is available as a generic. Side effects are common enough that some people stop it, mainly tingling in the hands and feet, tiredness, loss of appetite and taste changes. It is a sulfa drug, so stop it and call your doctor right away for any rash, unusual bruising or bleeding, or yellowing skin or eyes, and report rapid breathing or confusion too.

Clinical pearls

  • Tell every prescriber if you take aspirin regularly, because high-dose aspirin with methazolamide has caused coma and death.
  • Steroids such as prednisone raise the risk of low potassium, so expect blood tests for potassium and other salts.
  • Mention any past sulfa allergy before starting, and never restart it after a serious skin, blood or liver reaction.
  • Brief blurring of near vision and drowsiness can show up early, so hold off driving until you know how you react.
How we write & review this content — our editorial policy →
How you get itPrescription only
Comes asTablet
Earliest FDA record1959
Companies listing it with the FDA9
FDA label last updatedDec 4, 2023
FDA’s strongest warning (boxed)None on the label

Patient information guide A plain-language walkthrough of Methazolamide, written from its FDA label.

What Methazolamide is used for

▾

Methazolamide tablets are prescribed to lower pressure inside the eye when that pressure reduction is expected to be beneficial. Supported uses include:

  • Chronic open-angle glaucoma — the most common form of glaucoma, where eye pressure builds up gradually over time
  • Secondary glaucoma — elevated eye pressure caused by another underlying condition
  • Acute angle-closure glaucoma — used before surgery to bring eye pressure down ahead of the procedure

How Methazolamide works

▾

Methazolamide blocks an enzyme called carbonic anhydrase, which is involved in producing the clear fluid (aqueous humor) inside the eye. Less fluid production means less pressure build-up. Pressure typically starts falling within 2 to 4 hours, peaks around 6 to 8 hours after a dose, and the effect lasts 10 to 18 hours.

Although methazolamide is a sulfonamide derivative, it does not have meaningful antibiotic properties, and it is not used as a diuretic or seizure medication despite having mild effects in those areas.

Methazolamide dosage

▾

Methazolamide tablets are taken by mouth, usually two or three times a day. It may be taken alongside other glaucoma eye drops or agents your doctor prescribes. It takes about 7 days of regular dosing for the drug to reach a steady, consistent level in your body.

  • Take each dose as directed by your prescriber — do not change your schedule without asking them first
  • If you miss a dose, follow your prescriber's or pharmacist's guidance on what to do next

Dosing details from the FDA-approved label

From the Methazolamide prescribing information (“Dosage and Administration”). Doses are set by your prescriber for your product, condition, kidney function and age — never change a dose on your own.

  • Effective therapeutic dose (no specific condition named in the dosing text)
    • 50 mg to 100 mg two or three times daily
    • The drug may be used concomitantly with miotic and osmotic agents
Read the label’s full dosing text

DOSAGE AND ADMINISTRATION: The effective therapeutic dose administered varies from 50 mg to 100 mg two or three times daily. The drug may be used concomitantly with miotic and osmotic agents.

Read the full Dosage and Administration section on DailyMed →

Methazolamide side effects

▾

Side effects tend to show up most often early in treatment. Common ones include:

Common side effects

  • Tingling or "pins and needles" feeling in the hands and feet
  • Fatigue or malaise
  • Loss of appetite or taste changes
  • Nausea, vomiting, or diarrhea
  • Increased urination
  • Drowsiness or confusion
  • Ringing in the ears (tinnitus) or hearing changes
  • Temporary blurred or worsened near vision (transient myopia)
  • Fatigue, malaise, or feeling unwell
  • Temporary worsening of near vision (transient myopia) — this usually clears once the dose is reduced or stopped

When to get medical help

  • Get medical help right away if you develop a severe skin rash, blistering, or peeling — these can be signs of Stevens-Johnson syndrome or toxic epidermal necrolysis
  • Call your doctor if you notice unusual bruising, bleeding, or signs of infection — these may point to a serious blood disorder such as aplastic anemia or agranulocytosis
  • Seek care immediately for signs of liver problems: yellowing of the skin or eyes, severe nausea, or abdominal pain
  • Tell your doctor if you develop rapid breathing, extreme tiredness, or confusion — these may signal a dangerous acid-base imbalance
  • If you take high-dose aspirin, talk to your doctor right away if you experience poor appetite, rapid breathing, lethargy, or confusion

Methazolamide warnings and precautions

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  • Serious skin and blood reactions: Rarely, methazolamide has caused life-threatening skin conditions (Stevens-Johnson syndrome, toxic epidermal necrolysis) and dangerous blood disorders (aplastic anemia, agranulocytosis). Stop the drug and seek care immediately if you develop a spreading rash, blistering, unusual bruising, or frequent infections.
  • Liver damage: Serious liver reactions have occurred. Watch for yellowing of the skin or eyes, dark urine, or severe abdominal pain.
  • High-dose aspirin interaction: Taking methazolamide with high-dose aspirin can cause loss of appetite, rapid breathing, extreme tiredness, coma, and death. Tell your doctor if aspirin is part of your regular regimen.
  • Electrolyte and acid imbalances: Methazolamide can shift your body's mineral and acid-base balance. Your doctor may monitor your blood levels, especially potassium.
  • Contraindicated conditions: Do not use this medication if you have low sodium or potassium levels, significant kidney or liver disease, adrenal failure, or a blood acid imbalance (hyperchloremic acidosis).
  • Angle-closure glaucoma long-term use: Prolonged use is not appropriate for angle-closure glaucoma — it will not prevent permanent closure of the drainage angle in the eye.

Methazolamide interactions

▾

Methazolamide has two important drug interactions to know about:

  • High-dose aspirin: This combination has been linked to very serious outcomes including coma and death. Tell every member of your care team if you take aspirin in any amount.
  • Corticosteroids (steroid medications): Using steroids alongside methazolamide raises the risk of low potassium levels (hypokalemia), which can affect heart and muscle function. Your doctor may need to monitor your potassium.

Interactions listed in the FDA-approved label

From the Methazolamide prescribing information (“Drug Interactions”): what the manufacturer studied or reported to the FDA.

  • Steroid therapy: There is a potential for developing hypokalemia. Methazolamide should be used with caution in patients on steroid therapy.
  • High-dose aspirin: Anorexia, tachypnea, lethargy, coma and death have been reported with concomitant use of high-dose aspirin and carbonic anhydrase inhibitors. Caution is advised for patients receiving high-dose aspirin and methazolamide concomitantly (see WARNINGS).
Read the label’s full interactions text

Drug Interactions: Methazolamide should be used with caution in patients on steroid therapy because of the potential for developing hypokalemia. Caution is advised for patients receiving high-dose aspirin and methazolamide concomitantly, as anorexia, tachypnea, lethargy, coma and death have been reported with concomitant use of high-dose aspirin and carbonic anhydrase inhibitors (see WARNINGS ).

Read the full Drug Interactions section on DailyMed →

Not a complete list. The label covers the interactions the manufacturer studied or reported, and our own interaction database does not cover every medicine either. Bring your full medication list, including vitamins and herbal products, to your pharmacist.

🌿218 supplements and herbs with documented Methazolamide interactions, ranked by severity Check Methazolamide against a supplement or herb →

Before taking Methazolamide

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  • Tell your doctor if you have low sodium or potassium levels in your blood — methazolamide is contraindicated in these situations
  • Do not take this medication if you have marked kidney or liver disease or dysfunction
  • Avoid it if you have adrenal gland failure or a blood acid condition called hyperchloremic acidosis
  • People with cirrhosis should not use it — it can trigger hepatic encephalopathy (a serious brain complication from liver disease)
  • Do not use it long-term for angle-closure glaucoma — it will not stop the angle from closing permanently
  • Tell your doctor about any prior allergic reaction to sulfonamide (sulfa) drugs — cross-reactions are possible
  • Tell your prescriber about all medications you take, especially aspirin and steroids

Methazolamide overdose

▾

There are no reported cases of methazolamide overdose in humans. However, based on what is known, too much could cause electrolyte imbalances, increased acidity in the blood, and effects on the central nervous system. Treatment would focus on supportive care and monitoring blood electrolytes (especially potassium) and blood pH. There is no specific antidote — if you suspect an overdose, contact Poison Control or go to an emergency room.

What Methazolamide does in the body

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Methazolamide lowers the production of aqueous humor (the fluid inside the eye) by blocking carbonic anhydrase, reducing intraocular pressure. The pressure drop begins within 2 to 4 hours, peaks at 6 to 8 hours, and lasts 10 to 18 hours after a dose. It also has a mild, temporary diuretic effect — increasing urine output and causing excretion of sodium, potassium, and chloride — but it is not recommended or effective as a diuretic medication.

How your body processes Methazolamide

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Methazolamide is well absorbed after oral dosing, with peak blood levels reached 1 to 2 hours after taking a tablet. About 55% of the drug binds to proteins in the blood. It has a half-life of roughly 14 hours, meaning it takes about that long for half the drug to leave your system. About 25% is excreted unchanged in the urine over each dosing interval, and it takes approximately 7 days of regular dosing to reach a stable, steady level in the body.

How to store Methazolamide

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Store at 20°C to 25°C (68°F to 77°F). Dispense in a tight container as defined in the USP, with a child-resistant closure (as required).

Written from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

218

Supplements & herbs that interact with Methazolamide

218 supplements and herbal products have documented interactions with Methazolamide in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.

Severity mix
  • Major · 7
  • Moderate · 187
  • Minor · 24
ACTIVATED CHARCOAL Major AMERICAN HELLEBORE Major AMERICAN MISTLETOE Major LITHIUM Major OLEANDER Major TYRAMINE Major YELLOW DOCK Major ABUTA Moderate +210 more
Every supplement checked against Methazolamide — ranked by severity The full interaction hub: 7 major · 187 moderate · 24 minor · every one linked to its full report. Check Methazolamide against your exact supplements

Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.

7

Nutrient depletion considerations

Methazolamide has been associated with lower levels of 7 nutrients in the clinical literature. This does not mean a deficiency will occur — it means these may be worth discussing with your pharmacist or healthcare provider, especially with long-term use.

Evidence & significance mix
  • Higher significance · 2
  • Moderate · 2
  • Unrated · 3
POTASSIUM Major Depletion VITAMIN C Insignificant Depletion MAGNESIUM Moderate Depletion THIAMINE Moderate Depletion COENZYME Q10 Insufficient Evidence FOLIC ACID Insufficient Evidence SODIUM Insufficient Evidence
See the full Methazolamide nutrient depletion report

Educational information from a licensed clinical database (Natural Medicines) — not medical advice. Do not start or stop medications or supplements without professional guidance.

Methazolamide: pharmacist answers to common questions

Quick, plain-English answers to the questions patients ask most about Methazolamide — the kind of thing our pharmacy team would talk through with you at the counter.

What is methazolamide actually doing for my eyes?

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It's reducing the pressure inside your eye. Your eye constantly makes a fluid called aqueous humor, and methazolamide slows down how much of that fluid is produced. Less fluid means less pressure — and keeping that pressure under control helps protect your vision over time. You'll usually start to feel its effect within a few hours of each dose.

What side effects should I actually expect when I start taking it?

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The most common one people notice is a tingling or 'pins and needles' feeling in their hands and feet — it can be a little odd but it's well known with this type of drug. You might also feel more tired than usual, have some nausea or stomach upset, notice a change in how things taste, or need to urinate more often. These tend to ease up as your body adjusts. Let your doctor know if anything feels really bothersome.

Are there any side effects I should treat as an emergency?

▾
Yes — a few. Because methazolamide belongs to the sulfonamide drug family, it can very rarely cause severe skin reactions like widespread blistering or peeling, serious liver problems, or dangerous drops in your blood cell counts. If you develop a severe rash, unusual bruising, persistent fatigue combined with frequent infections, or yellowing of your skin or eyes, stop the medication and get medical help right away. These are rare, but they're serious enough that you shouldn't wait.

I take aspirin every day. Is that a problem?

▾
This is really important to flag with your doctor before you start. Taking methazolamide with high-dose aspirin has caused very serious reactions — including loss of appetite, rapid breathing, extreme drowsiness, and in rare cases, coma or death. Make sure your prescriber knows exactly how much aspirin you take, and don't adjust either medication on your own.

Are there people who absolutely shouldn't take this medication?

▾
Yes. Methazolamide isn't safe for everyone. It should not be used if your sodium or potassium blood levels are too low, if you have significant kidney or liver disease, adrenal gland failure, or a specific acid imbalance in your blood called hyperchloremic acidosis. If you have cirrhosis, it can cause a serious brain complication. Your doctor will review your health history before prescribing it — make sure they have the full picture.

How long does it take for methazolamide to really kick in and stabilize?

▾
Each individual dose starts working within a couple of hours and lasts up to 18 hours. But if you're wondering when the drug fully settles into a consistent level in your body, that takes about 7 days of taking it regularly. So give it about a week before you and your doctor evaluate how well it's working for you.

Is Methazolamide available over the counter?

▾
No. Methazolamide is a prescription medicine: every Methazolamide product listed with the FDA is prescription only, so it is not sold over the counter. Your prescriber decides whether it is appropriate for you, and your pharmacist dispenses it.

When was Methazolamide first available?

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The earliest FDA record we hold for Methazolamide is from 1959: its first approval in Drugs@FDA or its earliest product listing in the NDC Directory, whichever is older. Many older medicines were in use before their first formal FDA approval, so this is the earliest date on record, not necessarily when Methazolamide was first used.

Who makes Methazolamide?

▾
9 companies currently list Methazolamide products in the FDA's NDC Directory, including Bryant Ranch Prepack, ANI Pharmaceuticals, Inc., Ajanta Pharma USA Inc.. That count includes repackagers and distributors as well as manufacturers (companies that sell only the raw ingredient are not counted), so fewer companies actually make it; the label on your bottle names the one that supplied yours.

Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

More about Methazolamide on HelloPharmacist

📊Methazolamide supplement interactions218 checked — ranked by severity 🌿Drug & Supplement CheckerMethazolamide vs. vitamins & herbs 💬Ask a PharmacistFree answer, usually < 24h 🔎NDC & pricing lookupFind Methazolamide NDCs & costs 🅰️Browse Drugs A–ZLook up any medication
Detailed data & references for Methazolamide Forms & strengths, pricing, billing codes, manufacturers, safety reports and sourcing — the data behind the page. Most people can stop here. Each section below opens on a tap.

Methazolamide forms and strengths (how it comes)

Methazolamide is available in 1 form. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Tablet

By mouth
How this form is used
What it may be used for
  • Methazolamide tablets are used to lower intraocular pressure in chronic open-angle glaucoma
  • Methazolamide tablets are used in secondary glaucoma to reduce eye pressure
  • Methazolamide tablets are used before surgery in acute angle-closure glaucoma to lower eye pressure
Important instructions
  • Methazolamide tablets are taken by mouth two or three times daily as directed by your prescriber
  • Methazolamide tablets may be used together with other glaucoma medications such as miotics or osmotic agents
  • Follow your prescriber's instructions carefully — do not adjust your dose on your own
Available strengths 2 strengths
25 mg 50 mg
38 FDA-listed product records ⓘ

Methazolamide on the U.S. market: products, makers and brands

How Methazolamide appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

9 companies list 20 Methazolamide product records with the FDA, mostly as tablet; the earliest marketing or approval year on record is 1959. Brand names on the directory include Neptazane; the rest are generics.

1
Dose forms ⓘ
9
Labelers (makers, repackagers, distributors)
1
Brand names
20
FDA-listed product records ⓘ
1959
Earliest FDA record ⓘ

Also listed with the FDA, not a patient dose form: Powder (9) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

Bryant Ranch Prepack20%
ANI Pharmaceuticals, Inc.10%
Ajanta Pharma USA Inc.10%
Bausch & Lomb Incorporated10%
Golden State Medical Supply, Inc.10%
Micro Labs Limited10%
Other makers30%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

How widely Methazolamide is used (Medicaid data)

A general measure of how commonly Methazolamide is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Methazolamide is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

4,047
Medicaid prescriptions filled (Q1–Q4 2025)
$534,412 gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Methazolamide prescribed? Of the 1,601 medications we measure, Methazolamide ranks #1,081 by Medicaid prescriptions — more than 32% of them.

Where Methazolamide ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5
Total prescriptions — #1,081 of 1,601
#1,076 Efavirenz, Emtricitabi... 4,121 Rx #1,077 Naldemedine 4,103 Rx #1,078 Lofexidine 4,102 Rx #1,079 Epinastine Ophthalmic 4,100 Rx #1,080 Cromolyn Sodium Nasal... 4,088 Rx #1,081 Methazolamide 4,047 Rx #1,082 Teprotumumab-trbw Inje... 4,027 Rx #1,083 Deucravacitinib 4,009 Rx #1,084 Selumetinib 3,980 Rx #1,085 Zanubrutinib 3,956 Rx #1,086 Probenecid 3,947 Rx

Utilization by Methazolamide product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

The 50 mg oral tablet is the most-dispensed Methazolamide product — about 76% of these Medicaid prescriptions.

methazolamide 50 MG Oral Tablet Most dispensed

3,061 Medicaid prescriptions (Q1–Q4 2025) 76% of Methazolamide prescriptions shown $438,959 gross reimbursement (before rebates) ≈ $143 per prescription (gross)

Summed across the 5 of 25 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 197940

methazolamide 25 MG Oral Tablet

986 Medicaid prescriptions (Q1–Q4 2025) 24% of Methazolamide prescriptions shown $95,453 gross reimbursement (before rebates) ≈ $97 per prescription (gross)

Summed across the 4 of 23 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 197939

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Methazolamide, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 9 of 48 listed Methazolamide NDCs with Medicaid activity.

Compare Methazolamide products

A representative set of FDA-listed product records for Methazolamide — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Showing 20 of 20 products — FDA National Drug Code Directory. See every product, package size and price: browse all 20 Methazolamide NDCs →

Methazolamide recall history

A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.

The FDA’s enforcement reports list no Methazolamide recalls since July 2021.

✅No Methazolamide recalls on record since July 2021

Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Sep 24, 2026.

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Methazolamide RxCUI 6826 1 dose form · 2 strengths
  1. Dose form (SCDF) Oral Tablet RxCUI 372815 In current FDA listings
    Clinical drug / strength (SCD) 25 MG RxCUI 197939 50 MG RxCUI 197940

Look up RxCUI 6826 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

💵 What Methazolamide costs pharmacies (NADAC benchmark)

The national average invoice price pharmacies pay for the drug itself, from CMS's NADAC survey (data as of Sep 30, 2026). This is a supply-cost benchmark — not a retail price and not what you'd pay at the counter.

FormStrengthPharmacy acquisition benchmark
Tablet · Oral 25 mg $0.627 per tablet NDC details & price history
Tablet · Oral 50 mg $1.51 per tablet NDC details & price history
Why show this? Your out-of-pocket cost depends on insurance, pharmacy markup, and discounts — but the acquisition benchmark tells you whether the medication itself is inexpensive or costly, which strengths cost more per dose, and whether a cash-price quote is in a reasonable range. Each row links to the NDC-level record with its full price history.

Source: CMS National Average Drug Acquisition Cost (NADAC), a survey of retail pharmacy invoice prices. Benchmarks shown are the range across package sizes of a representative product for each form and strength — other manufacturers' products may differ.

Methazolamide brand names

Methazolamide is sold under one brand name in the FDA directory — Neptazane. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.

Neptazane

Who makes Methazolamide: manufacturers and labelers

9 companies list Methazolamide products with the FDA. By number of product records, the largest are Bryant Ranch Prepack, ANI Pharmaceuticals, Inc., Ajanta Pharma USA Inc.. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.

Bryant Ranch Prepack 4 ANI Pharmaceuticals, Inc. 2 Ajanta Pharma USA Inc. 2 Bausch & Lomb Incorporated 2 Golden State Medical Supply, Inc. 2 Micro Labs Limited 2 NorthStar Rx LLC 2 Padagis US LLC 2 Precision Dose, Inc. 2

Methazolamide drug class (RxNorm)

Methazolamide belongs to the Carbonic anhydrase inhibitors class.

Drug family (ATC) Carbonic anhydrase inhibitors

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

Sources for this Methazolamide page

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Dec 4, 2023
🏭
Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Methazolamide.
📈
Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
🚨
Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Methazolamide after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
12
Finished products in the current FDA directory
20
Companies listing them (makers, repackagers, distributors)
9
FDA labeler codes behind them ⓘ
10
Linked representative label ⓘ
Precision Dose, Inc.
Linked label effective
Dec 4, 2023
Composite sections available
15
Linked SPL Set ID
1e0e81c7-a328-4034-a6b3-4c83e9ac3a3e
Linked SPL Document ID
5dc8c6ca-5710-4369-b0ae-37666210f03b
Open the linked representative label on DailyMed ↗

How this page is built

HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. Precision Dose, Inc. is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →