Diltiazem drug information | HelloPharmacist

Why is this medication prescribed?
How should this medicine be used?
Other uses for this medicine
What special precautions should I follow?
What special dietary instructions should I follow?
What should I do if I forget a dose?
What side effects can this medication cause?
What should I know about STORAGE and DISPOSAL of this medication?
What should I do in case of OVERDOSE?
What OTHER INFORMATION should I know?
Brand names of combination products
Drug interactions

Why is this medication prescribed?

Diltiazem is used to treat high blood pressure and to control angina (chest pain). Diltiazem is in a class of medications called calcium-channel blockers. It works by relaxing the blood vessels so the heart does not have to pump as hard. It also increases the supply of blood and oxygen to the heart.

High blood pressure is a common condition, and when not treated it can cause damage to the brain, heart, blood vessels, kidneys, and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.

How should this medicine be used?

Diltiazem comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. The regular tablet is usually taken three or four times a day. The extended-release capsule and tablet are usually taken one or two times a day. Ask your pharmacist if you should take diltiazem with or without food, because instructions may vary with each product. Take diltiazem at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take diltiazem exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the extended-release capsules and tablets whole; do not chew or crush them.

Your doctor will probably start you on a low dose of diltiazem and gradually increase your dose, not more than once every 7 to 14 days if you are taking the extended-release tablet or capsule and not more than once every 1 to 2 days if you are taking the regular tablet.

If taken regularly, diltiazem may control chest pain, but it does not stop chest pain once it starts. Your doctor may give you a different medication to take when you have chest pain.

Diltiazem controls high blood pressure and chest pain (angina) but does not cure them. It may take up to 2 weeks before you feel the full benefit of diltiazem. Continue to take diltiazem even if you feel well. Do not stop taking diltiazem without talking to your doctor.

Other uses for this medicine

Diltiazem is also sometimes used to treat certain types of arrhythmias (abnormal heart rhythms). Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking diltiazem,

tell your doctor and pharmacist if you are allergic to diltiazem, any other medications, or any of the ingredients in diltiazem. Ask your pharmacist for a list of the ingredients.

tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: atazanavir (Reyataz); benzodiazepines such as midazolam (Versed) and triazolam (Halcion); beta blockers such as atenolol (Tenormin, in Tenoretic), labetalol, metoprolol (Lopressor, Toprol XL, in Dutoprol), nadolol (Corgard, in Corzide), and propranolol (Inderal, Innopran, in Inderide); buspirone; carbamazepine (Carbatrol, Epitol, Equetro, Tegretol); cimetidine (Tagamet); cyclosporine (Gengraf, Neoral, Sandimmune); digoxin (Lanoxin); lovastatin (Altoprev, Mevacor, in Advicor); quinidine (in Nuedexta); and rifampin (Rifadin, in Rifamate, in Rifater, Rimactane). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with diltiazem, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

tell your doctor if you have or have ever had a myocardial infarction (MI); a narrowing or blockage of your digestive system or any other condition that causes food to move through your digestive system more slowly; low blood pressure; or heart, liver, or kidney disease.

tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking diltiazem, call your doctor.

if you are having surgery, including dental surgery, tell your doctor or dentist that you are taking diltiazem.

What special dietary instructions should I follow?

If your doctor prescribes a low-salt or low-sodium diet, follow these directions carefully.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Diltiazem may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- dizziness or lightheadedness
- flushing
- headache
- weakness
- slow heartbeat
- vomiting
- diarrhea
- constipation
- nasal congestion
- cough

Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment:
- swelling of the face, eyes, lips, tongue, hands, arms, feet, ankles, or lower legs
- difficulty breathing or swallowing
- fainting
- rash
- yellowing of the skin or eyes
- nausea
- extreme tiredness
- unusual bleeding or bruising
- lack of energy
- loss of appetite
- pain in the upper right part of the stomach
- flu-like symptoms
- increase in frequency or severity of chest pain (angina)
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

What should I know about STORAGE and DISPOSAL of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

What should I do in case of OVERDOSE?

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include the following:

slow, fast, or irregular heartbeat
fainting
difficulty breathing
seizures
dizziness
confusion
nausea
vomiting
increased sweating

What OTHER INFORMATION should I know?

Keep all appointments with your doctor and the laboratory. Your blood pressure should be checked regularly to determine your response to diltiazem.

Your doctor may ask you to check your pulse (heart rate) daily and will tell you how fast it should be. If your pulse is slower than it should be, call your doctor for directions on taking diltiazem that day. Ask your doctor or pharmacist to teach you how to check your pulse.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand names of combination products

Teczem^® (containing Diltiazem, Enalapril)

Drug interactions

Drug	Interaction
Moxifloxacin	Moxifloxacin The risk or severity of QTc prolongation can be increased when Moxifloxacin is combined with Diltiazem.
Repaglinide	Repaglinide The metabolism of Repaglinide can be decreased when combined with Diltiazem.
Montelukast	Montelukast The metabolism of Diltiazem can be decreased when combined with Montelukast.
Insulin Glargine (rDNA origin) Injection	Insulin Glargine (rDNA origin) Injection The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Insulin glargine.
Leflunomide	Leflunomide The metabolism of Diltiazem can be decreased when combined with Leflunomide.
Delavirdine	Delavirdine The metabolism of Diltiazem can be decreased when combined with Delavirdine.
Nevirapine	Nevirapine The metabolism of Nevirapine can be decreased when combined with Diltiazem.
Atorvastatin	Atorvastatin The serum concentration of Diltiazem can be increased when it is combined with Atorvastatin.
Dolasetron	Dolasetron The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Dolasetron.
Aminophylline	Aminophylline The metabolism of Aminophylline can be decreased when combined with Diltiazem.
Anagrelide	Anagrelide The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Anagrelide.
Bisacodyl	Bisacodyl The therapeutic efficacy of Bisacodyl can be decreased when used in combination with Diltiazem.
Candesartan	Candesartan The metabolism of Diltiazem can be decreased when combined with Candesartan.
Cilostazol	Cilostazol The metabolism of Cilostazol can be decreased when combined with Diltiazem.
Clopidogrel	Clopidogrel The therapeutic efficacy of Clopidogrel can be decreased when used in combination with Diltiazem.
Erythromycin and Sulfisoxazole	Erythromycin and Sulfisoxazole The risk or severity of adverse effects can be increased when Erythromycin is combined with Diltiazem.
Fenofibrate	Fenofibrate The metabolism of Diltiazem can be decreased when combined with Fenofibrate.
Guanfacine	Guanfacine Guanfacine may decrease the antihypertensive activities of Diltiazem.
Magnesium Gluconate	Magnesium Gluconate The risk or severity of hypotension can be increased when Diltiazem is combined with Magnesium gluconate.
Magnesium Hydroxide	Magnesium Hydroxide The risk or severity of hypotension can be increased when Diltiazem is combined with Magnesium hydroxide.
Magnesium Oxide	Magnesium Oxide The risk or severity of hypotension can be increased when Diltiazem is combined with Magnesium oxide.
Methylergonovine	Methylergonovine Methylergometrine may decrease the antihypertensive activities of Diltiazem.
Miglitol	Miglitol The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Miglitol.
Naratriptan	Naratriptan Naratriptan may decrease the antihypertensive activities of Diltiazem.
Olsalazine	Olsalazine The risk or severity of bleeding can be increased when Diltiazem is combined with Olsalazine.
Paregoric	Paregoric The metabolism of Morphine can be decreased when combined with Diltiazem.
Penbutolol	Penbutolol The risk or severity of bradycardia can be increased when Diltiazem is combined with Acebutolol.
Polyethylene glycol-electrolyte solution (PEG-ES)	Polyethylene glycol-electrolyte solution (PEG-ES) The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Diltiazem.
Potassium	Potassium Potassium may increase the hyperkalemic activities of Diltiazem.
Psyllium	Psyllium The therapeutic efficacy of Plantago seed can be decreased when used in combination with Diltiazem.
Ranitidine	Ranitidine The metabolism of Diltiazem can be decreased when combined with Ranitidine.
Reserpine	Reserpine The metabolism of Diltiazem can be increased when combined with Reserpine.
Rizatriptan	Rizatriptan Rizatriptan may decrease the antihypertensive activities of Diltiazem.
Sumatriptan	Sumatriptan Sumatriptan may decrease the antihypertensive activities of Diltiazem.
Tacrolimus	Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Diltiazem.
Tizanidine	Tizanidine The risk or severity of QTc prolongation can be increased when Tizanidine is combined with Diltiazem.
Triamcinolone	Triamcinolone The metabolism of Diltiazem can be decreased when combined with Triamcinolone.
Zolmitriptan	Zolmitriptan Zolmitriptan may decrease the antihypertensive activities of Diltiazem.
Famotidine Injection	Famotidine Injection The risk or severity of QTc prolongation can be increased when Famotidine is combined with Diltiazem.
Fluconazole Injection	Fluconazole Injection The metabolism of Diltiazem can be decreased when combined with Fluconazole.
Foscarnet Injection	Foscarnet Injection The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Diltiazem.
Hydromorphone Injection	Hydromorphone Injection The metabolism of Diltiazem can be decreased when combined with Hydromorphone.
Levofloxacin Injection	Levofloxacin Injection The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Levofloxacin.
Meperidine Injection	Meperidine Injection The metabolism of Meperidine can be decreased when combined with Diltiazem.
Metoclopramide Injection	Metoclopramide Injection The metabolism of Diltiazem can be decreased when combined with Metoclopramide.
Metronidazole Injection	Metronidazole Injection The metabolism of Metronidazole can be decreased when combined with Diltiazem.
Morphine Injection	Morphine Injection The metabolism of Morphine can be decreased when combined with Diltiazem.
Zidovudine Injection	Zidovudine Injection The metabolism of Zidovudine can be decreased when combined with Diltiazem.
Altretamine	Altretamine Amphetamine may increase the hypotensive activities of Diltiazem.
Cyclosporine	Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Diltiazem.
Ondansetron	Ondansetron The metabolism of Ondansetron can be decreased when combined with Diltiazem.
Enoxaparin Injection	Enoxaparin Injection The risk or severity of hyperkalemia can be increased when Diltiazem is combined with Enoxaparin.
Granisetron	Granisetron The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Granisetron.
Torsemide	Torsemide The metabolism of Torasemide can be decreased when combined with Diltiazem.
Olanzapine	Olanzapine The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Diltiazem.
Alosetron	Alosetron The metabolism of Alosetron can be decreased when combined with Diltiazem.
Dofetilide	Dofetilide Diltiazem may increase the arrhythmogenic activities of Dofetilide.
Entacapone	Entacapone The metabolism of Diltiazem can be decreased when combined with Entacapone.
Eprosartan	Eprosartan The risk or severity of hyperkalemia can be increased when Diltiazem is combined with Eprosartan.
Hydroxychloroquine	Hydroxychloroquine The metabolism of Diltiazem can be decreased when combined with Hydroxychloroquine.
Meloxicam	Meloxicam The therapeutic efficacy of Meloxicam can be decreased when used in combination with Diltiazem.
Oxcarbazepine	Oxcarbazepine The metabolism of Diltiazem can be increased when combined with Oxcarbazepine.
Telmisartan	Telmisartan The risk or severity of hyperkalemia can be increased when Diltiazem is combined with Telmisartan.
Zaleplon	Zaleplon The metabolism of Zaleplon can be decreased when combined with Diltiazem.
Anakinra	Anakinra The metabolism of Diltiazem can be increased when combined with Anakinra.
Desloratadine	Desloratadine The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Desloratadine.
Linezolid	Linezolid Linezolid may increase the hypotensive activities of Diltiazem.
Rivastigmine	Rivastigmine Diltiazem may increase the bradycardic activities of Rivastigmine.
Trimipramine	Trimipramine The metabolism of Diltiazem can be decreased when combined with Trimipramine.
Etanercept Injection	Etanercept Injection The metabolism of Diltiazem can be increased when combined with Etanercept.
Modafinil	Modafinil The metabolism of Diltiazem can be increased when combined with Modafinil.
Perindopril	Perindopril The risk or severity of hyperkalemia can be increased when Diltiazem is combined with Perindopril.
Tenofovir	Tenofovir The metabolism of Tenofovir can be decreased when combined with Diltiazem.
Choline Magnesium Trisalicylate	Choline Magnesium Trisalicylate The therapeutic efficacy of Diltiazem can be decreased when used in combination with Choline magnesium trisalicylate.
Sirolimus	Sirolimus Diltiazem may increase the immunosuppressive activities of Sirolimus.
Dutasteride	Dutasteride The metabolism of Dutasteride can be decreased when combined with Diltiazem.
Epinephrine Injection	Epinephrine Injection The metabolism of Diltiazem can be decreased when combined with Epinephrine.
Eplerenone	Eplerenone The metabolism of Eplerenone can be decreased when combined with Diltiazem.
Escitalopram	Escitalopram The serum concentration of Escitalopram can be increased when it is combined with Diltiazem.
Olmesartan	Olmesartan The risk or severity of hyperkalemia can be increased when Olmesartan is combined with Diltiazem.
Zonisamide	Zonisamide Zonisamide may increase the arrhythmogenic activities of Diltiazem.
Adalimumab Injection	Adalimumab Injection The metabolism of Diltiazem can be increased when combined with Adalimumab.
Aripiprazole	Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Diltiazem.
Atomoxetine	Atomoxetine The risk or severity of QTc prolongation can be increased when Atomoxetine is combined with Diltiazem.
Dexmethylphenidate	Dexmethylphenidate Dexmethylphenidate may decrease the antihypertensive activities of Diltiazem.
Atazanavir	Atazanavir The metabolism of Diltiazem can be decreased when combined with Atazanavir.
Almotriptan	Almotriptan The metabolism of Almotriptan can be decreased when combined with Diltiazem.
Eletriptan	Eletriptan Eletriptan may decrease the antihypertensive activities of Diltiazem.
Mefloquine	Mefloquine The risk or severity of QTc prolongation can be increased when Mefloquine is combined with Diltiazem.
Polyethylene Glycol 3350	Polyethylene Glycol 3350 The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Diltiazem.
Rosuvastatin	Rosuvastatin The metabolism of Rosuvastatin can be decreased when combined with Diltiazem.
Vardenafil	Vardenafil The metabolism of Vardenafil can be decreased when combined with Diltiazem.
Alfuzosin	Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Diltiazem.
Aprepitant	Aprepitant The metabolism of Aprepitant can be decreased when combined with Diltiazem.
Tegaserod	Tegaserod The metabolism of Tegaserod can be decreased when combined with Diltiazem.
Tadalafil	Tadalafil The metabolism of Tadalafil can be decreased when combined with Diltiazem.
Frovatriptan	Frovatriptan Frovatriptan may decrease the antihypertensive activities of Diltiazem.
Gemifloxacin	Gemifloxacin The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Gemifloxacin.
Progesterone	Progesterone The metabolism of Progesterone can be decreased when combined with Diltiazem.
Apomorphine Injection	Apomorphine Injection The risk or severity of QTc prolongation can be increased when Apomorphine is combined with Diltiazem.
Infliximab Injection	Infliximab Injection The metabolism of Diltiazem can be increased when combined with Infliximab.
Oxandrolone	Oxandrolone The metabolism of Diltiazem can be decreased when combined with Oxandrolone.
Protriptyline	Protriptyline The risk or severity of QTc prolongation can be increased when Protriptyline is combined with Diltiazem.
Rifaximin	Rifaximin The metabolism of Diltiazem can be increased when combined with Rifaximin.
Duloxetine	Duloxetine The risk or severity of orthostatic hypotension and syncope can be increased when Diltiazem is combined with Duloxetine.
Norethindrone	Norethindrone The metabolism of Norethisterone can be decreased when combined with Diltiazem.
Trospium	Trospium The metabolism of Diltiazem can be decreased when combined with Trospium.
Bosentan	Bosentan The metabolism of Diltiazem can be increased when combined with Bosentan.
Cinacalcet	Cinacalcet The metabolism of Diltiazem can be decreased when combined with Cinacalcet.
Erlotinib	Erlotinib The metabolism of Diltiazem can be decreased when combined with Erlotinib.
Eszopiclone	Eszopiclone The metabolism of Eszopiclone can be decreased when combined with Diltiazem.
Insulin Aspart (rDNA Origin) Injection	Insulin Aspart (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Insulin aspart.
Solifenacin	Solifenacin The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Diltiazem.
Voriconazole	Voriconazole The metabolism of Diltiazem can be decreased when combined with Voriconazole.
Dextroamphetamine	Dextroamphetamine Amphetamine may increase the hypotensive activities of Diltiazem.
Peginterferon Alfa-2b (PEG-Intron)	Peginterferon Alfa-2b (PEG-Intron) The metabolism of Diltiazem can be increased when combined with Peginterferon alfa-2b.
Pramlintide Injection	Pramlintide Injection The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Pramlintide.
Exenatide Injection	Exenatide Injection The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Exenatide.
Ibandronate	Ibandronate The risk or severity of QTc prolongation can be increased when Ibandronate is combined with Diltiazem.
Isocarboxazid	Isocarboxazid Isocarboxazid may increase the hypotensive activities of Diltiazem.
Ramelteon	Ramelteon The metabolism of Ramelteon can be decreased when combined with Diltiazem.
Darifenacin	Darifenacin The metabolism of Darifenacin can be decreased when combined with Diltiazem.
Fentanyl	Fentanyl The metabolism of Fentanyl can be decreased when combined with Diltiazem.
Pregabalin	Pregabalin Pregabalin may increase the arrhythmogenic activities of Diltiazem.
Deferasirox	Deferasirox The metabolism of Diltiazem can be decreased when combined with Deferasirox.
Phenylephrine	Phenylephrine The risk or severity of hypertension can be decreased when Phenylephrine is combined with Diltiazem.
Tipranavir	Tipranavir The metabolism of Tipranavir can be decreased when combined with Diltiazem.
Felbamate	Felbamate The risk or severity of QTc prolongation can be increased when Felbamate is combined with Diltiazem.
Insulin Detemir (rDNA Origin) Injection	Insulin Detemir (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Insulin detemir.
Ranolazine	Ranolazine The metabolism of Diltiazem can be decreased when combined with Ranolazine.
Abatacept Injection	Abatacept Injection The metabolism of Diltiazem can be increased when combined with Abatacept.
Rasagiline	Rasagiline Rasagiline may increase the hypotensive activities of Diltiazem.
Imatinib	Imatinib The risk or severity of QTc prolongation can be increased when Imatinib is combined with Diltiazem.
Sitagliptin	Sitagliptin The metabolism of Sitagliptin can be decreased when combined with Diltiazem.
Gefitinib	Gefitinib The metabolism of Diltiazem can be decreased when combined with Gefitinib.
Albuterol	Albuterol The risk or severity of QTc prolongation can be increased when Salbutamol is combined with Diltiazem.
Paliperidone	Paliperidone The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Paliperidone.
Bortezomib	Bortezomib The metabolism of Diltiazem can be decreased when combined with Bortezomib.
Clofarabine Injection	Clofarabine Injection The risk or severity of adverse effects can be increased when Clofarabine is combined with Diltiazem.
Insulin Glulisine (rDNA origin) Injection	Insulin Glulisine (rDNA origin) Injection The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Insulin glulisine.
Lubiprostone	Lubiprostone The therapeutic efficacy of Lubiprostone can be decreased when used in combination with Diltiazem.
Oxaliplatin Injection	Oxaliplatin Injection The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Oxaliplatin.
Posaconazole	Posaconazole The risk or severity of QTc prolongation can be increased when Posaconazole is combined with Diltiazem.
Primaquine	Primaquine The metabolism of Diltiazem can be decreased when combined with Primaquine.
Rituximab Injection	Rituximab Injection Diltiazem may increase the hypotensive activities of Rituximab.
Aliskiren	Aliskiren The risk or severity of hyperkalemia can be increased when Diltiazem is combined with Aliskiren.
Bismuth Subsalicylate	Bismuth Subsalicylate The risk or severity of bleeding can be increased when Diltiazem is combined with Bismuth subsalicylate.
Darunavir	Darunavir The serum concentration of Darunavir can be increased when it is combined with Diltiazem.
Dimenhydrinate	Dimenhydrinate The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Dimenhydrinate.
Lisdexamfetamine	Lisdexamfetamine The metabolism of Diltiazem can be decreased when combined with Lisdexamfetamine.
Nabilone	Nabilone The metabolism of Diltiazem can be decreased when combined with Nabilone.
Retapamulin	Retapamulin The metabolism of Retapamulin can be decreased when combined with Diltiazem.
Vorinostat	Vorinostat The risk or severity of QTc prolongation can be increased when Vorinostat is combined with Diltiazem.
Sorafenib	Sorafenib The metabolism of Diltiazem can be decreased when combined with Sorafenib.
Sunitinib	Sunitinib The metabolism of Sunitinib can be decreased when combined with Diltiazem.
Dronabinol	Dronabinol The metabolism of Dronabinol can be decreased when combined with Diltiazem.
Lapatinib	Lapatinib The metabolism of Lapatinib can be decreased when combined with Diltiazem.
Levocetirizine	Levocetirizine The risk or severity of QTc prolongation can be increased when Levocetirizine is combined with Diltiazem.
Dasatinib	Dasatinib The metabolism of Dasatinib can be decreased when combined with Diltiazem.
Mexiletine	Mexiletine Diltiazem may increase the arrhythmogenic activities of Mexiletine.
Armodafinil	Armodafinil The metabolism of Diltiazem can be increased when combined with Armodafinil.
Paclitaxel (with polyoxyethylated castor oil) Injection	Paclitaxel (with polyoxyethylated castor oil) Injection The therapeutic efficacy of Castor oil can be decreased when used in combination with Diltiazem.
Temsirolimus	Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Diltiazem.
Nilotinib	Nilotinib The metabolism of Nilotinib can be decreased when combined with Diltiazem.
Toremifene	Toremifene The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Toremifene.
Bexarotene	Bexarotene The metabolism of Diltiazem can be decreased when combined with Bexarotene.
Budesonide	Budesonide The metabolism of Diltiazem can be increased when combined with Budesonide.
Chloramphenicol Injection	Chloramphenicol Injection The metabolism of Diltiazem can be decreased when combined with Chloramphenicol.
Desmopressin	Desmopressin Desmopressin may decrease the antihypertensive activities of Diltiazem.
Etravirine	Etravirine The metabolism of Diltiazem can be decreased when combined with Etravirine.
Arsenic Trioxide Injection	Arsenic Trioxide Injection The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Arsenic trioxide.
Desvenlafaxine	Desvenlafaxine The metabolism of Diltiazem can be decreased when combined with Desvenlafaxine.
Cevimeline	Cevimeline The metabolism of Diltiazem can be decreased when combined with Cevimeline.
Nebivolol	Nebivolol The risk or severity of bradycardia can be increased when Diltiazem is combined with Nebivolol.
Tretinoin	Tretinoin The metabolism of Tretinoin can be decreased when combined with Diltiazem.
Flecainide	Flecainide Diltiazem may increase the arrhythmogenic activities of Flecainide.
Certolizumab Injection	Certolizumab Injection The metabolism of Diltiazem can be increased when combined with Certolizumab pegol.
Ixabepilone Injection	Ixabepilone Injection The metabolism of Ixabepilone can be decreased when combined with Diltiazem.
Irinotecan Injection	Irinotecan Injection The metabolism of Irinotecan can be decreased when combined with Diltiazem.
Praziquantel	Praziquantel The metabolism of Praziquantel can be decreased when combined with Diltiazem.
Rufinamide	Rufinamide The metabolism of Rufinamide can be decreased when combined with Diltiazem.
Silodosin	Silodosin The risk or severity of hypotension can be increased when Silodosin is combined with Diltiazem.
Midazolam	Midazolam The serum concentration of Midazolam can be increased when it is combined with Diltiazem.
Eltrombopag	Eltrombopag The metabolism of Eltrombopag can be decreased when combined with Diltiazem.
Sodium Phosphate	Sodium Phosphate Diltiazem may increase the hyperkalemic activities of Sodium phosphate, monobasic.
Fesoterodine	Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Diltiazem.
Degarelix Injection	Degarelix Injection The risk or severity of QTc prolongation can be increased when Degarelix is combined with Diltiazem.
Betaxolol	Betaxolol The risk or severity of bradycardia can be increased when Betaxolol is combined with Diltiazem.
Iloperidone	Iloperidone The metabolism of Iloperidone can be decreased when combined with Diltiazem.
Prasugrel	Prasugrel The metabolism of Prasugrel can be decreased when combined with Diltiazem.
Lacosamide	Lacosamide The metabolism of Lacosamide can be decreased when combined with Diltiazem.
Everolimus	Everolimus The metabolism of Everolimus can be decreased when combined with Diltiazem.
Tolvaptan (low blood sodium)	Tolvaptan (low blood sodium) The metabolism of Tolvaptan can be decreased when combined with Diltiazem.
Dronedarone	Dronedarone The serum concentration of Dronedarone can be increased when it is combined with Diltiazem.
Palonosetron Injection	Palonosetron Injection The metabolism of Palonosetron can be decreased when combined with Diltiazem.
Saxagliptin	Saxagliptin The metabolism of Saxagliptin can be decreased when combined with Diltiazem.
Telavancin Injection	Telavancin Injection The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Telavancin.
Romidepsin Injection	Romidepsin Injection The metabolism of Romidepsin can be decreased when combined with Diltiazem.
Tapentadol	Tapentadol The metabolism of Diltiazem can be decreased when combined with Tapentadol.
Golimumab Injection	Golimumab Injection The metabolism of Diltiazem can be increased when combined with Golimumab.
Pazopanib	Pazopanib The metabolism of Pazopanib can be decreased when combined with Diltiazem.
Asenapine	Asenapine The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Asenapine.
Pitavastatin	Pitavastatin The metabolism of Pitavastatin can be decreased when combined with Diltiazem.
Albendazole	Albendazole The metabolism of Albendazole can be decreased when combined with Diltiazem.
Levonorgestrel	Levonorgestrel The metabolism of Levonorgestrel can be decreased when combined with Diltiazem.
Oxymorphone	Oxymorphone The metabolism of Oxymorphone can be decreased when combined with Diltiazem.
Liraglutide Injection	Liraglutide Injection The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Liraglutide.
Tocilizumab Injection	Tocilizumab Injection The metabolism of Diltiazem can be increased when combined with Tocilizumab.
Fingolimod	Fingolimod The risk or severity of bradycardia can be increased when Diltiazem is combined with Fingolimod.
Eribulin Injection	Eribulin Injection The risk or severity of QTc prolongation can be increased when Eribulin is combined with Diltiazem.
Cabazitaxel Injection	Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Diltiazem.
Lurasidone	Lurasidone The metabolism of Lurasidone can be decreased when combined with Diltiazem.
Acetaminophen Injection	Acetaminophen Injection The metabolism of Diltiazem can be decreased when combined with Acetaminophen.
Vilazodone	Vilazodone The metabolism of Vilazodone can be decreased when combined with Diltiazem.
Denileukin Diftitox Injection	Denileukin Diftitox Injection The risk or severity of adverse effects can be increased when Aldesleukin is combined with Diltiazem.
Terbutaline Injection	Terbutaline Injection The risk or severity of QTc prolongation can be increased when Terbutaline is combined with Diltiazem.
Azilsartan	Azilsartan The risk or severity of hyperkalemia can be increased when Diltiazem is combined with Azilsartan medoxomil.
Busulfan Injection	Busulfan Injection The metabolism of Busulfan can be decreased when combined with Diltiazem.
Roflumilast	Roflumilast The metabolism of Roflumilast can be decreased when combined with Diltiazem.
Linagliptin	Linagliptin The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Linagliptin.
Rilpivirine	Rilpivirine The risk or severity of QTc prolongation can be increased when Rilpivirine is combined with Diltiazem.
Potassium Iodide	Potassium Iodide Potassium Iodide may increase the hyperkalemic activities of Diltiazem.
Cyclophosphamide Injection	Cyclophosphamide Injection The metabolism of Cyclophosphamide can be decreased when combined with Diltiazem.
Abiraterone	Abiraterone The metabolism of Diltiazem can be decreased when combined with Abiraterone.
Triptorelin Injection	Triptorelin Injection The risk or severity of QTc prolongation can be increased when Triptorelin is combined with Diltiazem.
Rivaroxaban	Rivaroxaban The metabolism of Rivaroxaban can be decreased when combined with Diltiazem.
Ticagrelor	Ticagrelor The metabolism of Diltiazem can be decreased when combined with Ticagrelor.
Brentuximab Vedotin Injection	Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be decreased when combined with Diltiazem.
Ruxolitinib	Ruxolitinib Ruxolitinib may increase the bradycardic activities of Diltiazem.
Vandetanib	Vandetanib The metabolism of Vandetanib can be decreased when combined with Diltiazem.
Clobazam	Clobazam The metabolism of Clobazam can be decreased when combined with Diltiazem.
Vemurafenib	Vemurafenib The metabolism of Diltiazem can be decreased when combined with Vemurafenib.
Vismodegib	Vismodegib The metabolism of Diltiazem can be decreased when combined with Vismodegib.
Ivacaftor	Ivacaftor The metabolism of Ivacaftor can be decreased when combined with Diltiazem.
Axitinib	Axitinib The metabolism of Axitinib can be decreased when combined with Diltiazem.
Crizotinib	Crizotinib The metabolism of Crizotinib can be decreased when combined with Diltiazem.
Cabergoline	Cabergoline The metabolism of Diltiazem can be decreased when combined with Cabergoline.
Ambrisentan	Ambrisentan The metabolism of Ambrisentan can be decreased when combined with Diltiazem.
Iloprost	Iloprost Iloprost may increase the hypotensive activities of Diltiazem.
Enzalutamide	Enzalutamide The metabolism of Diltiazem can be increased when combined with Enzalutamide.
Mirabegron	Mirabegron The metabolism of Mirabegron can be decreased when combined with Diltiazem.
Regorafenib	Regorafenib The metabolism of Diltiazem can be decreased when combined with Regorafenib.
Bosutinib	Bosutinib The metabolism of Diltiazem can be decreased when combined with Bosutinib.
Linaclotide	Linaclotide The therapeutic efficacy of Linaclotide can be decreased when used in combination with Diltiazem.
Teriflunomide	Teriflunomide The metabolism of Diltiazem can be decreased when combined with Teriflunomide.
Lorcaserin	Lorcaserin The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Mecasermin.
Cabozantinib (thyroid cancer)	Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Diltiazem.
Bedaquiline	Bedaquiline The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Bedaquiline.
Tofacitinib	Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Diltiazem.
Alogliptin	Alogliptin The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Alogliptin.
Ponatinib	Ponatinib The metabolism of Ponatinib can be decreased when combined with Diltiazem.
Pomalidomide	Pomalidomide The metabolism of Pomalidomide can be decreased when combined with Diltiazem.
Ado-trastuzumab Emtansine Injection	Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be decreased when combined with Diltiazem.
Apixaban	Apixaban The metabolism of Apixaban can be decreased when combined with Diltiazem.
Canagliflozin	Canagliflozin The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Canagliflozin.
Methazolamide	Methazolamide The risk or severity of adverse effects can be increased when Methazolamide is combined with Diltiazem.
Dabrafenib	Dabrafenib The metabolism of Diltiazem can be decreased when combined with Dabrafenib.
Ospemifene	Ospemifene The metabolism of Ospemifene can be decreased when combined with Diltiazem.
Trametinib	Trametinib The metabolism of Diltiazem can be decreased when combined with Trametinib.
Levomilnacipran	Levomilnacipran The metabolism of Levomilnacipran can be decreased when combined with Diltiazem.
Vortioxetine	Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Diltiazem.
Perampanel	Perampanel The metabolism of Perampanel can be decreased when combined with Diltiazem.
Ibrutinib	Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Diltiazem.
Lomitapide	Lomitapide The metabolism of Lomitapide can be decreased when combined with Diltiazem.
Avanafil	Avanafil The metabolism of Avanafil can be decreased when combined with Diltiazem.
Ketorolac Injection	Ketorolac Injection The therapeutic efficacy of Diltiazem can be decreased when used in combination with Ketorolac.
Obinutuzumab Injection	Obinutuzumab Injection Diltiazem may increase the hypotensive activities of Obinutuzumab.
Dapagliflozin	Dapagliflozin The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Dapagliflozin.
Apremilast	Apremilast The metabolism of Diltiazem can be increased when combined with Apremilast.
Droxidopa	Droxidopa Droxidopa may decrease the antihypertensive activities of Diltiazem.
Ceritinib	Ceritinib Diltiazem may increase the bradycardic activities of Ceritinib.
Siltuximab Injection	Siltuximab Injection The metabolism of Diltiazem can be increased when combined with Siltuximab.
Albiglutide Injection	Albiglutide Injection The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Albiglutide.
Idelalisib	Idelalisib The metabolism of Idelalisib can be decreased when combined with Diltiazem.
Testosterone Injection	Testosterone Injection The metabolism of Testosterone can be decreased when combined with Diltiazem.
Oritavancin Injection	Oritavancin Injection The metabolism of Diltiazem can be decreased when combined with Oritavancin.
Empagliflozin	Empagliflozin The risk or severity of hypoglycemia can be increased when Empagliflozin is combined with Diltiazem.
Vorapaxar	Vorapaxar The metabolism of Vorapaxar can be decreased when combined with Diltiazem.
Suvorexant	Suvorexant The metabolism of Suvorexant can be decreased when combined with Diltiazem.
Dulaglutide Injection	Dulaglutide Injection The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Dulaglutide.
Olaparib	Olaparib The metabolism of Olaparib can be decreased when combined with Diltiazem.
Methamphetamine	Methamphetamine The metabolism of Metamfetamine can be decreased when combined with Diltiazem.
Tasimelteon	Tasimelteon The metabolism of Tasimelteon can be decreased when combined with Diltiazem.
Riociguat	Riociguat The metabolism of Riociguat can be decreased when combined with Diltiazem.
Lanreotide Injection	Lanreotide Injection Diltiazem may increase the bradycardic activities of Lanreotide.
Nintedanib	Nintedanib The metabolism of Nintedanib can be decreased when combined with Diltiazem.
Secukinumab Injection	Secukinumab Injection The metabolism of Diltiazem can be increased when combined with Secukinumab.
Risperidone Injection	Risperidone Injection Diltiazem may increase the hypotensive activities of Risperidone.
Palbociclib	Palbociclib The metabolism of Palbociclib can be decreased when combined with Diltiazem.
Insulin Human Inhalation	Insulin Human Inhalation The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Insulin human.
Lenvatinib	Lenvatinib The metabolism of Diltiazem can be decreased when combined with Lenvatinib.
Naloxegol	Naloxegol The metabolism of Naloxegol can be decreased when combined with Diltiazem.
Panobinostat	Panobinostat The metabolism of Panobinostat can be decreased when combined with Diltiazem.
Dinutuximab Injection	Dinutuximab Injection The risk or severity of adverse effects can be increased when Dinutuximab is combined with Diltiazem.
Haloperidol Injection	Haloperidol Injection The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Haloperidol.
Ivabradine	Ivabradine The metabolism of Ivabradine can be decreased when combined with Diltiazem.
Amiloride	Amiloride The risk or severity of hyperkalemia can be increased when Diltiazem is combined with Amiloride.
Isavuconazonium Injection	Isavuconazonium Injection The therapeutic efficacy of Isavuconazonium can be increased when used in combination with Diltiazem.
Macitentan	Macitentan Diltiazem may increase the hypotensive activities of Macitentan.
Sonidegib	Sonidegib The metabolism of Sonidegib can be decreased when combined with Diltiazem.
Flibanserin	Flibanserin The metabolism of Diltiazem can be decreased when combined with Flibanserin.
Rolapitant	Rolapitant The metabolism of Rolapitant can be decreased when combined with Diltiazem.
Daclatasvir	Daclatasvir The metabolism of Daclatasvir can be decreased when combined with Diltiazem.
Brexpiprazole	Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Diltiazem.
Ziprasidone Injection	Ziprasidone Injection The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Ziprasidone.
Cariprazine	Cariprazine Cariprazine may decrease the antihypertensive activities of Diltiazem.
Insulin Degludec (rDNA Origin) Injection	Insulin Degludec (rDNA Origin) Injection The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Insulin degludec.
Cobimetinib	Cobimetinib The metabolism of Cobimetinib can be decreased when combined with Diltiazem.
Trabectedin Injection	Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Diltiazem.
Osimertinib	Osimertinib The metabolism of Osimertinib can be decreased when combined with Diltiazem.
Alectinib	Alectinib The metabolism of Alectinib can be decreased when combined with Diltiazem.
Ixazomib	Ixazomib The metabolism of Ixazomib can be decreased when combined with Diltiazem.
Rifapentine	Rifapentine The metabolism of Diltiazem can be increased when combined with Rifapentine.
Lesinurad	Lesinurad The metabolism of Lesinurad can be decreased when combined with Diltiazem.
Amphotericin B Liposomal Injection	Amphotericin B Liposomal Injection Diltiazem may decrease the nephrotoxic activities of Amphotericin B.
Dexamethasone Injection	Dexamethasone Injection The metabolism of Dexamethasone can be decreased when combined with Diltiazem.
Brivaracetam Injection	Brivaracetam Injection The metabolism of Brivaracetam can be decreased when combined with Diltiazem.
Venetoclax	Venetoclax The metabolism of Venetoclax can be decreased when combined with Diltiazem.
Cobicistat	Cobicistat The metabolism of Diltiazem can be decreased when combined with Cobicistat.
Midodrine	Midodrine Midodrine may decrease the antihypertensive activities of Diltiazem.
Selexipag	Selexipag The metabolism of Selexipag can be decreased when combined with Diltiazem.
Diphenhydramine Injection	Diphenhydramine Injection The metabolism of Diltiazem can be decreased when combined with Diphenhydramine.
Furosemide Injection	Furosemide Injection Furosemide may increase the hypotensive activities of Diltiazem.
Rucaparib	Rucaparib The metabolism of Diltiazem can be decreased when combined with Rucaparib.
Lixisenatide Injection	Lixisenatide Injection The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Lixisenatide.
Ribociclib	Ribociclib The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Ribociclib.
Brigatinib	Brigatinib The metabolism of Brigatinib can be decreased when combined with Diltiazem.
Doxepin (Insomnia)	Doxepin (Insomnia) The metabolism of Doxepin can be decreased when combined with Diltiazem.
Plecanatide	Plecanatide The therapeutic efficacy of Plecanatide can be decreased when used in combination with Diltiazem.
Deutetrabenazine	Deutetrabenazine The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Deutetrabenazine.
Valbenazine	Valbenazine The metabolism of Valbenazine can be decreased when combined with Diltiazem.
Deflazacort	Deflazacort The serum concentration of Diltiazem can be increased when it is combined with Deflazacort.
Safinamide	Safinamide Safinamide may increase the hypotensive activities of Diltiazem.
Midostaurin	Midostaurin The metabolism of Diltiazem can be decreased when combined with Midostaurin.
Neratinib	Neratinib The metabolism of Neratinib can be decreased when combined with Diltiazem.
Enasidenib	Enasidenib The metabolism of Enasidenib can be decreased when combined with Diltiazem.
Aprepitant/Fosaprepitant Injection	Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be decreased when combined with Diltiazem.
Copanlisib Injection	Copanlisib Injection The metabolism of Copanlisib can be decreased when combined with Diltiazem.
Delafloxacin	Delafloxacin The risk or severity of QTc prolongation can be increased when Delafloxacin is combined with Diltiazem.
Abemaciclib	Abemaciclib The metabolism of Abemaciclib can be decreased when combined with Diltiazem.
Acalabrutinib	Acalabrutinib The metabolism of Diltiazem can be decreased when combined with Acalabrutinib.
Letermovir	Letermovir The metabolism of Diltiazem can be decreased when combined with Letermovir.
Semaglutide Injection	Semaglutide Injection The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Semaglutide.
Tetrabenazine	Tetrabenazine The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Tetrabenazine.
Ertugliflozin	Ertugliflozin The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Ertugliflozin.
Buprenorphine Injection	Buprenorphine Injection The metabolism of Buprenorphine can be decreased when combined with Diltiazem.
Apalutamide	Apalutamide The metabolism of Diltiazem can be decreased when combined with Apalutamide.
Fostamatinib	Fostamatinib Fostamatinib may increase the antihypertensive activities of Diltiazem.
Avatrombopag	Avatrombopag The metabolism of Diltiazem can be increased when combined with Avatrombopag.
Baricitinib	Baricitinib The metabolism of Baricitinib can be decreased when combined with Diltiazem.
Lofexidine	Lofexidine The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Lofexidine.
Eliglustat	Eliglustat The metabolism of Eliglustat can be decreased when combined with Diltiazem.
Encorafenib	Encorafenib The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Encorafenib.
Ivosidenib	Ivosidenib The metabolism of Ivosidenib can be decreased when combined with Diltiazem.
Elagolix	Elagolix The metabolism of Elagolix can be decreased when combined with Diltiazem.
Doravirine	Doravirine The metabolism of Doravirine can be decreased when combined with Diltiazem.
Tafenoquine	Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Diltiazem.
Cannabidiol	Cannabidiol The metabolism of Cannabidiol can be decreased when combined with Diltiazem.
Dacomitinib	Dacomitinib The metabolism of Diltiazem can be decreased when combined with Dacomitinib.
Duvelisib	Duvelisib The metabolism of Duvelisib can be decreased when combined with Diltiazem.
Stiripentol	Stiripentol The metabolism of Diltiazem can be decreased when combined with Stiripentol.
Gilteritinib	Gilteritinib The metabolism of Gilteritinib can be decreased when combined with Diltiazem.
Glasdegib	Glasdegib The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Glasdegib.
Lorlatinib	Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Diltiazem.
Paclitaxel (with albumin) Injection	Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Diltiazem.
Rifamycin	Rifamycin The metabolism of Diltiazem can be decreased when combined with Rifamycin.
Prucalopride	Prucalopride The metabolism of Prucalopride can be decreased when combined with Diltiazem.
Magnesium Citrate	Magnesium Citrate The risk or severity of hypotension can be increased when Diltiazem is combined with Magnesium citrate.
Emapalumab-lzsg Injection	Emapalumab-lzsg Injection The metabolism of Diltiazem can be increased when combined with Emapalumab.
Siponimod	Siponimod The risk or severity of adverse effects can be increased when Diltiazem is combined with Siponimod.
Erdafitinib	Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Diltiazem.
Alpelisib	Alpelisib The serum concentration of Diltiazem can be decreased when it is combined with Alpelisib.
Solriamfetol	Solriamfetol Solriamfetol may decrease the antihypertensive activities of Diltiazem.
Triclabendazole	Triclabendazole The risk or severity of QTc prolongation can be increased when Triclabendazole is combined with Diltiazem.
Entrectinib	Entrectinib The metabolism of Entrectinib can be decreased when combined with Diltiazem.
Pexidartinib	Pexidartinib The metabolism of Pexidartinib can be decreased when combined with Diltiazem.
Istradefylline	Istradefylline The metabolism of Istradefylline can be decreased when combined with Diltiazem.
Pitolisant	Pitolisant The serum concentration of Diltiazem can be decreased when it is combined with Pitolisant.
Pretomanid	Pretomanid The serum concentration of Pretomanid can be increased when it is combined with Diltiazem.
Fedratinib	Fedratinib The metabolism of Diltiazem can be decreased when combined with Fedratinib.
Lefamulin	Lefamulin Diltiazem may increase the QTc-prolonging activities of Lefamulin.
Phenytoin Injection	Phenytoin Injection The metabolism of Phenytoin can be decreased when combined with Diltiazem.
Fosphenytoin Injection	Fosphenytoin Injection The metabolism of Fosphenytoin can be decreased when combined with Diltiazem.
Zanubrutinib	Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Diltiazem.
Voxelotor	Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Diltiazem.
Avapritinib	Avapritinib The metabolism of Avapritinib can be decreased when combined with Diltiazem.
Lumateperone	Lumateperone The serum concentration of Lumateperone can be increased when it is combined with Diltiazem.
Lasmiditan	Lasmiditan Lasmiditan may increase the bradycardic activities of Diltiazem.
Ubrogepant	Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Diltiazem.
Calcium Acetate	Calcium Acetate The therapeutic efficacy of Diltiazem can be decreased when used in combination with Calcium acetate.
Tazemetostat	Tazemetostat The metabolism of Tazemetostat can be decreased when combined with Diltiazem.
Cenobamate	Cenobamate The serum concentration of Cenobamate can be decreased when it is combined with Diltiazem.
Pemigatinib	Pemigatinib The metabolism of Pemigatinib can be decreased when combined with Diltiazem.
Ozanimod	Ozanimod The metabolism of Ozanimod can be decreased when combined with Diltiazem.
Selumetinib	Selumetinib The serum concentration of Selumetinib can be increased when it is combined with Diltiazem.
Rimegepant	Rimegepant The metabolism of Rimegepant can be decreased when combined with Diltiazem.
Tucatinib	Tucatinib The metabolism of Tucatinib can be decreased when combined with Diltiazem.
Selpercatinib	Selpercatinib The serum concentration of Diltiazem can be increased when it is combined with Selpercatinib.
Capmatinib	Capmatinib The serum concentration of Capmatinib can be increased when it is combined with Diltiazem.
Lemborexant	Lemborexant The serum concentration of Lemborexant can be increased when it is combined with Diltiazem.
Fenfluramine	Fenfluramine The metabolism of Diltiazem can be decreased when combined with Fenfluramine.
Fostemsavir	Fostemsavir The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Diltiazem.
Lurbinectedin Injection	Lurbinectedin Injection The serum concentration of Lurbinectedin can be increased when it is combined with Diltiazem.
Octreotide	Octreotide The serum concentration of the active metabolites of Diltiazem can be increased when Diltiazem is used in combination with Octreotide.
Pralsetinib	Pralsetinib The metabolism of Diltiazem can be decreased when combined with Pralsetinib.
Opicapone	Opicapone The metabolism of Diltiazem can be decreased when combined with Opicapone.
Satralizumab-mwge Injection	Satralizumab-mwge Injection The serum concentration of Diltiazem can be decreased when it is combined with Satralizumab.
Naxitamab-gqgk Injection	Naxitamab-gqgk Injection Naxitamab may decrease the antihypertensive activities of Diltiazem.
Relugolix	Relugolix The risk or severity of QTc prolongation can be increased when Relugolix is combined with Diltiazem.
Progestin-Only (drospirenone) Oral Contraceptives	Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Drospirenone can be decreased when combined with Diltiazem.
Theophylline	Theophylline The metabolism of Diltiazem can be decreased when combined with Theophylline.
Fenoprofen	Fenoprofen The therapeutic efficacy of Diltiazem can be decreased when used in combination with Fenoprofen.
Indomethacin	Indomethacin The therapeutic efficacy of Diltiazem can be decreased when used in combination with Indomethacin.
Mefenamic Acid	Mefenamic Acid The therapeutic efficacy of Diltiazem can be decreased when used in combination with Mefenamic acid.
Naproxen	Naproxen The therapeutic efficacy of Diltiazem can be decreased when used in combination with Naproxen.
Tolmetin	Tolmetin The therapeutic efficacy of Diltiazem can be decreased when used in combination with Tolmetin.
Sulindac	Sulindac The therapeutic efficacy of Diltiazem can be decreased when used in combination with Sulindac.
Trazodone	Trazodone The risk or severity of QTc prolongation can be increased when Trazodone is combined with Diltiazem.
Hydroxyurea	Hydroxyurea The metabolism of Diltiazem can be decreased when combined with Hydroxyurea.
Floxuridine	Floxuridine The metabolism of Diltiazem can be decreased when combined with Floxuridine.
Phenobarbital	Phenobarbital The metabolism of Phenobarbital can be decreased when combined with Diltiazem.
Methotrexate Injection	Methotrexate Injection The metabolism of Methotrexate can be decreased when combined with Diltiazem.
Primidone	Primidone The metabolism of Primidone can be increased when combined with Diltiazem.
Methsuximide	Methsuximide Methsuximide may increase the arrhythmogenic activities of Diltiazem.
Diethylpropion	Diethylpropion Diethylpropion may decrease the antihypertensive activities of Diltiazem.
Chlorpromazine	Chlorpromazine The metabolism of Chlorpromazine can be decreased when combined with Diltiazem.
Diazepam	Diazepam The metabolism of Diazepam can be decreased when combined with Diltiazem.
Lorazepam	Lorazepam The metabolism of Lorazepam can be decreased when combined with Diltiazem.
Phenoxybenzamine	Phenoxybenzamine The risk or severity of hypotension can be increased when Phenoxybenzamine is combined with Diltiazem.
Amantadine	Amantadine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Diltiazem.
Codeine	Codeine The metabolism of Diltiazem can be decreased when combined with Codeine.
Bromocriptine	Bromocriptine The risk or severity of hypotension can be increased when Bromocriptine is combined with Diltiazem.
Metaproterenol	Metaproterenol Orciprenaline may decrease the antihypertensive activities of Diltiazem.
Tranylcypromine	Tranylcypromine The metabolism of Diltiazem can be decreased when combined with Tranylcypromine.
Phenelzine	Phenelzine Phenelzine may increase the hypotensive activities of Diltiazem.
Procarbazine	Procarbazine Procarbazine may increase the hypotensive activities of Diltiazem.
Ergoloid Mesylates	Ergoloid Mesylates Ergoloid mesylate may decrease the antihypertensive activities of Diltiazem.
Prochlorperazine	Prochlorperazine The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Prochlorperazine.
Thioridazine	Thioridazine The metabolism of Diltiazem can be decreased when combined with Thioridazine.
Trifluoperazine	Trifluoperazine The risk or severity of hypotension can be increased when Trifluoperazine is combined with Diltiazem.
Dapsone	Dapsone The metabolism of Dapsone can be decreased when combined with Diltiazem.
Sulfadiazine	Sulfadiazine The metabolism of Sulfadiazine can be decreased when combined with Diltiazem.
Oxycodone	Oxycodone The metabolism of Oxycodone can be decreased when combined with Diltiazem.
Methadone	Methadone The metabolism of Methadone can be decreased when combined with Diltiazem.
Oxybutynin	Oxybutynin The metabolism of Diltiazem can be decreased when combined with Oxybutynin.
Benztropine	Benztropine The risk or severity of QTc prolongation can be increased when Benzatropine is combined with Diltiazem.
Colestipol	Colestipol Colestipol can cause a decrease in the absorption of Diltiazem resulting in a reduced serum concentration and potentially a decrease in efficacy.
Maprotiline	Maprotiline The risk or severity of QTc prolongation can be increased when Maprotiline is combined with Diltiazem.
Ibuprofen	Ibuprofen The therapeutic efficacy of Diltiazem can be decreased when used in combination with Ibuprofen.
Orphenadrine	Orphenadrine The metabolism of Diltiazem can be decreased when combined with Orphenadrine.
Perphenazine	Perphenazine The metabolism of Perphenazine can be decreased when combined with Diltiazem.
Fluphenazine	Fluphenazine The metabolism of Diltiazem can be decreased when combined with Fluphenazine.
Phentermine	Phentermine The metabolism of Phentermine can be decreased when combined with Diltiazem.
Methylphenidate	Methylphenidate Methylphenidate may decrease the antihypertensive activities of Diltiazem.
Amoxapine	Amoxapine The metabolism of Diltiazem can be decreased when combined with Amoxapine.
Sulfasalazine	Sulfasalazine The risk or severity of bleeding can be increased when Diltiazem is combined with Sulfasalazine.
Hydrocortisone	Hydrocortisone The metabolism of Hydrocortisone can be decreased when combined with Diltiazem.
Doxorubicin	Doxorubicin The metabolism of Diltiazem can be decreased when combined with Doxorubicin.
Carbamazepine	Carbamazepine The metabolism of Carbamazepine can be decreased when combined with Diltiazem.
Methyldopa	Methyldopa Diltiazem may increase the hypotensive activities of Methyldopa.
Clonidine	Clonidine Diltiazem may increase the atrioventricular blocking (AV block) activities of Clonidine.
Prazosin	Prazosin The risk or severity of hypotension can be increased when Prazosin is combined with Diltiazem.
Hydralazine	Hydralazine Diltiazem may increase the hypotensive activities of Hydralazine.
Cimetidine	Cimetidine The serum concentration of Diltiazem can be increased when it is combined with Cimetidine.
Warfarin	Warfarin The serum concentration of Warfarin can be increased when it is combined with Diltiazem.
Loperamide	Loperamide Diltiazem may increase the arrhythmogenic activities of Loperamide.
Promethazine	Promethazine The metabolism of Diltiazem can be decreased when combined with Promethazine.
Meclofenamate	Meclofenamate The therapeutic efficacy of Diltiazem can be decreased when used in combination with Meclofenamic acid.
Daunorubicin	Daunorubicin The metabolism of Diltiazem can be increased when combined with Daunorubicin.
Nitrofurantoin	Nitrofurantoin The risk or severity of hyperkalemia can be increased when Diltiazem is combined with Nitrofurantoin.
Griseofulvin	Griseofulvin The metabolism of Diltiazem can be increased when combined with Griseofulvin.
Digoxin	Digoxin The serum concentration of Digoxin can be increased when it is combined with Diltiazem.
Chloroquine	Chloroquine The metabolism of Chloroquine can be decreased when combined with Diltiazem.
Quinine	Quinine The metabolism of Quinine can be decreased when combined with Diltiazem.
Ethosuximide	Ethosuximide Ethosuximide may increase the arrhythmogenic activities of Diltiazem.
Triamterene	Triamterene The risk or severity of hyperkalemia can be increased when Diltiazem is combined with Triamterene.
Lactulose	Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Diltiazem.
Sulfinpyrazone	Sulfinpyrazone The metabolism of Diltiazem can be decreased when combined with Sulfinpyrazone.
Chlorothiazide	Chlorothiazide The therapeutic efficacy of Chlorothiazide can be increased when used in combination with Diltiazem.
Chlorthalidone	Chlorthalidone Chlorthalidone may increase the hypotensive activities of Diltiazem.
Metolazone	Metolazone Diltiazem may increase the hypotensive activities of Metolazone.
Isosorbide	Isosorbide Diltiazem may increase the vasodilatory activities of Isosorbide.
Clindamycin Injection	Clindamycin Injection The metabolism of Clindamycin can be decreased when combined with Diltiazem.
Secobarbital	Secobarbital The metabolism of Diltiazem can be increased when combined with Secobarbital.
Desipramine	Desipramine The metabolism of Desipramine can be decreased when combined with Diltiazem.
Amitriptyline	Amitriptyline The metabolism of Diltiazem can be decreased when combined with Amitriptyline.
Imipramine	Imipramine The metabolism of Imipramine can be decreased when combined with Diltiazem.
Probenecid	Probenecid The metabolism of Diltiazem can be increased when combined with Probenecid.
Quinidine	Quinidine Diltiazem may increase the arrhythmogenic activities of Quinidine.
Procainamide	Procainamide Diltiazem may increase the arrhythmogenic activities of Procainamide.
Isoniazid	Isoniazid The metabolism of Diltiazem can be decreased when combined with Isoniazid.
Rifampin	Rifampin The metabolism of Diltiazem can be increased when combined with Rifampicin.
Disopyramide	Disopyramide Diltiazem may increase the arrhythmogenic activities of Disopyramide.
Valproic Acid	Valproic Acid The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Valproic acid.
Tamoxifen	Tamoxifen The metabolism of Tamoxifen can be decreased when combined with Diltiazem.
Butabarbital	Butabarbital Butabarbital may increase the hypotensive activities of Diltiazem.
Levothyroxine	Levothyroxine The metabolism of Diltiazem can be decreased when combined with Levothyroxine.
Methimazole	Methimazole The metabolism of Diltiazem can be decreased when combined with Methimazole.
Chlorpropamide	Chlorpropamide The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Chlorpropamide.
Tolbutamide	Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Diltiazem.
Tolazamide	Tolazamide The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Tolazamide.
Dextromethorphan	Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Diltiazem.
Niacin	Niacin The metabolism of Diltiazem can be decreased when combined with Niacin.
Baclofen	Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Diltiazem.
Doxylamine	Doxylamine The risk or severity of QTc prolongation can be increased when Doxylamine is combined with Diltiazem.
Cyproheptadine	Cyproheptadine The risk or severity of QTc prolongation can be increased when Cyproheptadine is combined with Diltiazem.
Clemastine	Clemastine The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Clemastine.
Chlorpheniramine	Chlorpheniramine The metabolism of Chlorpheniramine can be decreased when combined with Diltiazem.
Brompheniramine	Brompheniramine The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Diltiazem.
Meclizine	Meclizine The metabolism of Meclizine can be decreased when combined with Diltiazem.
Methyclothiazide	Methyclothiazide The therapeutic efficacy of Diltiazem can be increased when used in combination with Methyclothiazide.
Hydrochlorothiazide	Hydrochlorothiazide The therapeutic efficacy of Diltiazem can be increased when used in combination with Hydrochlorothiazide.
Dantrolene	Dantrolene The risk or severity of hyperkalemia can be increased when Dantrolene is combined with Diltiazem.
Chlorzoxazone	Chlorzoxazone The metabolism of Chlorzoxazone can be decreased when combined with Diltiazem.
Disulfiram	Disulfiram The risk or severity of QTc prolongation can be increased when Disulfiram is combined with Diltiazem.
Propranolol (Cardiovascular)	Propranolol (Cardiovascular) The risk or severity of bradycardia can be increased when Diltiazem is combined with Propranolol.
Minoxidil	Minoxidil Diltiazem may increase the hypotensive activities of Minoxidil.
Pseudoephedrine	Pseudoephedrine Pseudoephedrine may decrease the antihypertensive activities of Diltiazem.
Nortriptyline	Nortriptyline The metabolism of Diltiazem can be decreased when combined with Nortriptyline.
Spironolactone	Spironolactone The metabolism of Diltiazem can be decreased when combined with Spironolactone.
Amphotericin B Injection	Amphotericin B Injection Diltiazem may decrease the nephrotoxic activities of Amphotericin B.
Nadolol	Nadolol The risk or severity of bradycardia can be increased when Diltiazem is combined with Nadolol.
Oxytocin Injection	Oxytocin Injection The risk or severity of QTc prolongation can be increased when Oxytocin is combined with Diltiazem.
Papaverine	Papaverine The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Papaverine.
Fluorouracil Injection	Fluorouracil Injection The metabolism of Fluorouracil can be decreased when combined with Diltiazem.
Colchicine	Colchicine The metabolism of Colchicine can be decreased when combined with Diltiazem.
Cephalexin	Cephalexin The metabolism of Cephalexin can be decreased when combined with Diltiazem.
Ketoconazole	Ketoconazole The metabolism of Diltiazem can be decreased when combined with Ketoconazole.
Thiotepa Injection	Thiotepa Injection The metabolism of Thiotepa can be decreased when combined with Diltiazem.
Vincristine Injection	Vincristine Injection The metabolism of Vincristine can be decreased when combined with Diltiazem.
Captopril	Captopril The risk or severity of hyperkalemia can be increased when Diltiazem is combined with Captopril.
Dipyridamole	Dipyridamole Dipyridamole may increase the antihypertensive activities of Diltiazem.
Isoxsuprine	Isoxsuprine Isoxsuprine may decrease the antihypertensive activities of Diltiazem.
Vinblastine	Vinblastine The metabolism of Diltiazem can be decreased when combined with Vinblastine.
Ethacrynic Acid	Ethacrynic Acid The risk or severity of adverse effects can be increased when Etacrynic acid is combined with Diltiazem.
Metoprolol	Metoprolol The metabolism of Metoprolol can be decreased when combined with Diltiazem.
Hydroxyzine	Hydroxyzine The risk or severity of QTc prolongation can be increased when Hydroxyzine is combined with Diltiazem.
Thiothixene	Thiothixene The risk or severity of QTc prolongation can be increased when Thiothixene is combined with Diltiazem.
Aspirin	Aspirin The risk or severity of bleeding can be increased when Diltiazem is combined with Acetylsalicylic acid.
Salsalate	Salsalate The therapeutic efficacy of Diltiazem can be decreased when used in combination with Salsalate.
Alprazolam	Alprazolam The metabolism of Alprazolam can be decreased when combined with Diltiazem.
Triazolam	Triazolam The metabolism of Triazolam can be decreased when combined with Diltiazem.
Hyoscyamine	Hyoscyamine Hyoscyamine may increase the arrhythmogenic activities of Diltiazem.
Trimethoprim	Trimethoprim The metabolism of Trimethoprim can be decreased when combined with Diltiazem.
Nifedipine	Nifedipine The serum concentration of Nifedipine can be increased when it is combined with Diltiazem.
Timolol	Timolol The risk or severity of adverse effects can be increased when Diltiazem is combined with Timolol.
Verapamil	Verapamil Diltiazem may increase the arrhythmogenic activities of Verapamil.
Atenolol	Atenolol The risk or severity of bradycardia can be increased when Diltiazem is combined with Atenolol.
Pindolol	Pindolol The risk or severity of bradycardia can be increased when Diltiazem is combined with Pindolol.
Cisplatin Injection	Cisplatin Injection The metabolism of Diltiazem can be decreased when combined with Cisplatin.
Diflunisal	Diflunisal The risk or severity of bleeding can be increased when Diltiazem is combined with Diflunisal.
Piroxicam	Piroxicam The therapeutic efficacy of Diltiazem can be decreased when used in combination with Piroxicam.
Bumetanide	Bumetanide The risk or severity of adverse effects can be increased when Bumetanide is combined with Diltiazem.
Etoposide	Etoposide The metabolism of Etoposide can be decreased when combined with Diltiazem.
Glyburide	Glyburide The metabolism of Diltiazem can be decreased when combined with Glyburide.
Glipizide	Glipizide The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Glipizide.
Indapamide	Indapamide The therapeutic efficacy of Diltiazem can be increased when used in combination with Indapamide.
Nafcillin Injection	Nafcillin Injection The therapeutic efficacy of Diltiazem can be decreased when used in combination with Nafcillin.
Pentoxifylline	Pentoxifylline Pentoxifylline may increase the hypotensive activities of Diltiazem.
Pentamidine Injection	Pentamidine Injection The metabolism of Pentamidine can be decreased when combined with Diltiazem.
Labetalol	Labetalol The risk or severity of bradycardia can be increased when Labetalol is combined with Diltiazem.
Leuprolide Injection	Leuprolide Injection The risk or severity of QTc prolongation can be increased when Leuprolide is combined with Diltiazem.
Gemfibrozil	Gemfibrozil The metabolism of Diltiazem can be decreased when combined with Gemfibrozil.
Guanabenz	Guanabenz Diltiazem may decrease the antihypertensive activities of Guanabenz.
Ketoprofen	Ketoprofen The therapeutic efficacy of Diltiazem can be decreased when used in combination with Ketoprofen.
Pimozide	Pimozide The metabolism of Pimozide can be decreased when combined with Diltiazem.
Enalapril	Enalapril The risk or severity of hyperkalemia can be increased when Diltiazem is combined with Enalapril.
Flurbiprofen	Flurbiprofen The therapeutic efficacy of Diltiazem can be decreased when used in combination with Flurbiprofen.
Amiodarone	Amiodarone The risk or severity of adverse effects can be increased when Diltiazem is combined with Amiodarone.
Buspirone	Buspirone The serum concentration of Buspirone can be increased when it is combined with Diltiazem.
Lovastatin	Lovastatin The serum concentration of Lovastatin can be increased when it is combined with Diltiazem.
Ciprofloxacin	Ciprofloxacin The metabolism of Diltiazem can be decreased when combined with Ciprofloxacin.
Mesalamine	Mesalamine The risk or severity of bleeding can be increased when Diltiazem is combined with Mesalazine.
Diclofenac	Diclofenac The metabolism of Diclofenac can be decreased when combined with Diltiazem.
Fluoxetine	Fluoxetine The serum concentration of Diltiazem can be increased when it is combined with Fluoxetine.
Nimodipine	Nimodipine Nimodipine may increase the arrhythmogenic activities of Diltiazem.
Clozapine	Clozapine The metabolism of Clozapine can be decreased when combined with Diltiazem.
Idarubicin	Idarubicin The metabolism of Idarubicin can be decreased when combined with Diltiazem.
Ofloxacin	Ofloxacin The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Ofloxacin.
Clarithromycin	Clarithromycin The risk or severity of adverse effects can be increased when Clarithromycin is combined with Diltiazem.
Benazepril	Benazepril The risk or severity of hyperkalemia can be increased when Diltiazem is combined with Benazepril.
Etodolac	Etodolac The therapeutic efficacy of Diltiazem can be decreased when used in combination with Etodolac.
Felodipine	Felodipine Diltiazem may increase the arrhythmogenic activities of Felodipine.
Fosinopril	Fosinopril The risk or severity of hyperkalemia can be increased when Diltiazem is combined with Fosinopril.
Nabumetone	Nabumetone The therapeutic efficacy of Diltiazem can be decreased when used in combination with Nabumetone.
Quinapril	Quinapril The risk or severity of hyperkalemia can be increased when Diltiazem is combined with Quinapril.
Ramipril	Ramipril The risk or severity of hyperkalemia can be increased when Ramipril is combined with Diltiazem.
Simvastatin	Simvastatin The serum concentration of Simvastatin can be increased when it is combined with Diltiazem.
Amlodipine	Amlodipine Amlodipine may increase the arrhythmogenic activities of Diltiazem.
Teniposide Injection	Teniposide Injection The metabolism of Diltiazem can be decreased when combined with Teniposide.
Itraconazole	Itraconazole The metabolism of Diltiazem can be decreased when combined with Itraconazole.
Lisinopril	Lisinopril The risk or severity of hyperkalemia can be increased when Diltiazem is combined with Lisinopril.
Oxaprozin	Oxaprozin The therapeutic efficacy of Diltiazem can be decreased when used in combination with Oxaprozin.
Atovaquone	Atovaquone The metabolism of Diltiazem can be decreased when combined with Atovaquone.
Rifabutin	Rifabutin The metabolism of Diltiazem can be increased when combined with Rifabutin.
Sotalol	Sotalol The risk or severity of bradycardia can be increased when Diltiazem is combined with Sotalol.
Bisoprolol	Bisoprolol The therapeutic efficacy of Diltiazem can be increased when used in combination with Bisoprolol.
Zolpidem	Zolpidem The metabolism of Zolpidem can be decreased when combined with Diltiazem.
Doxazosin	Doxazosin The risk or severity of hypotension can be increased when Doxazosin is combined with Diltiazem.
Terazosin	Terazosin The risk or severity of hypotension can be increased when Diltiazem is combined with Terazosin.
Isradipine	Isradipine Isradipine may increase the arrhythmogenic activities of Diltiazem.
Omeprazole	Omeprazole The metabolism of Omeprazole can be decreased when combined with Diltiazem.
Cisapride	Cisapride The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Cisapride.
Fluvastatin	Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Diltiazem.
Venlafaxine	Venlafaxine The metabolism of Diltiazem can be decreased when combined with Venlafaxine.
Famciclovir	Famciclovir The metabolism of Famciclovir can be decreased when combined with Diltiazem.
Fluvoxamine	Fluvoxamine The metabolism of Diltiazem can be decreased when combined with Fluvoxamine.
Nefazodone	Nefazodone The risk or severity of hypotension can be increased when Nefazodone is combined with Diltiazem.
Lamotrigine	Lamotrigine Diltiazem may increase the arrhythmogenic activities of Lamotrigine.
Losartan	Losartan Diltiazem may increase the arrhythmogenic activities of Losartan.
Tramadol	Tramadol The metabolism of Tramadol can be decreased when combined with Diltiazem.
Vinorelbine Injection	Vinorelbine Injection The metabolism of Diltiazem can be decreased when combined with Vinorelbine.
Moexipril	Moexipril The risk or severity of QTc prolongation can be increased when Moexipril is combined with Diltiazem.
Lansoprazole	Lansoprazole The metabolism of Lansoprazole can be decreased when combined with Diltiazem.
Ifosfamide Injection	Ifosfamide Injection The metabolism of Ifosfamide can be decreased when combined with Diltiazem.
Nicardipine	Nicardipine The metabolism of Diltiazem can be decreased when combined with Nicardipine.
Bupropion	Bupropion The metabolism of Diltiazem can be decreased when combined with Bupropion.
Ticlopidine	Ticlopidine The metabolism of Ticlopidine can be decreased when combined with Diltiazem.
Saquinavir	Saquinavir The metabolism of Diltiazem can be decreased when combined with Saquinavir.
Metformin	Metformin The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Metformin.
Dalteparin Injection	Dalteparin Injection The risk or severity of hyperkalemia can be increased when Diltiazem is combined with Dalteparin.
Nisoldipine	Nisoldipine Diltiazem may increase the arrhythmogenic activities of Nisoldipine.
Amifostine Injection	Amifostine Injection Diltiazem may increase the hypotensive activities of Amifostine.
Acarbose	Acarbose The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Acarbose.
Glimepiride	Glimepiride Glimepiride may increase the arrhythmogenic activities of Diltiazem.
Anastrozole	Anastrozole The metabolism of Anastrozole can be decreased when combined with Diltiazem.
Indinavir	Indinavir The metabolism of Indinavir can be decreased when combined with Diltiazem.
Ritonavir	Ritonavir The serum concentration of Ritonavir can be increased when it is combined with Diltiazem.
Docetaxel Injection	Docetaxel Injection The metabolism of Docetaxel can be decreased when combined with Diltiazem.
Clomipramine	Clomipramine The metabolism of Diltiazem can be decreased when combined with Clomipramine.
Zafirlukast	Zafirlukast The metabolism of Diltiazem can be decreased when combined with Zafirlukast.
Mirtazapine	Mirtazapine The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Diltiazem.
Trandolapril	Trandolapril The risk or severity of hyperkalemia can be increased when Diltiazem is combined with Trandolapril.
Zileuton	Zileuton The metabolism of Zileuton can be decreased when combined with Diltiazem.
Valsartan	Valsartan The metabolism of Diltiazem can be decreased when combined with Valsartan.
Insulin Lispro Injection	Insulin Lispro Injection The risk or severity of hypoglycemia can be increased when Diltiazem is combined with Insulin lispro.
Pramipexole	Pramipexole The risk or severity of adverse effects can be increased when Pramipexole is combined with Diltiazem.
Donepezil	Donepezil The metabolism of Donepezil can be decreased when combined with Diltiazem.
Nelfinavir	Nelfinavir The metabolism of Diltiazem can be decreased when combined with Nelfinavir.
Azithromycin	Azithromycin The metabolism of Azithromycin can be decreased when combined with Diltiazem.
Loratadine	Loratadine The metabolism of Diltiazem can be decreased when combined with Loratadine.
Carvedilol	Carvedilol The risk or severity of bradycardia can be increased when Carvedilol is combined with Diltiazem.
Nilutamide	Nilutamide The metabolism of Diltiazem can be decreased when combined with Nilutamide.
Flutamide	Flutamide The metabolism of Flutamide can be decreased when combined with Diltiazem.
Selegiline	Selegiline Selegiline may increase the hypotensive activities of Diltiazem.
Bicalutamide	Bicalutamide The metabolism of Diltiazem can be decreased when combined with Bicalutamide.
Sertraline	Sertraline The metabolism of Diltiazem can be decreased when combined with Sertraline.
Propafenone	Propafenone The risk or severity of bradycardia can be increased when Propafenone is combined with Diltiazem.
Raloxifene	Raloxifene The metabolism of Diltiazem can be decreased when combined with Raloxifene.
Irbesartan	Irbesartan The metabolism of Irbesartan can be decreased when combined with Diltiazem.
Tamsulosin	Tamsulosin The risk or severity of hypotension can be increased when Tamsulosin is combined with Diltiazem.
Ropinirole	Ropinirole The risk or severity of adverse effects can be increased when Ropinirole is combined with Diltiazem.
Finasteride	Finasteride The metabolism of Finasteride can be decreased when combined with Diltiazem.
Quetiapine	Quetiapine Diltiazem may increase the hypotensive activities of Quetiapine.
Cetirizine	Cetirizine The risk or severity of QTc prolongation can be increased when Cetirizine is combined with Diltiazem.
Paroxetine	Paroxetine The metabolism of Diltiazem can be decreased when combined with Paroxetine.
Tolcapone	Tolcapone The metabolism of Diltiazem can be decreased when combined with Tolcapone.
Citalopram	Citalopram The risk or severity of QTc prolongation can be increased when Diltiazem is combined with Citalopram.
Capecitabine	Capecitabine The metabolism of Diltiazem can be decreased when combined with Capecitabine.
Efavirenz	Efavirenz The serum concentration of Diltiazem can be decreased when it is combined with Efavirenz.
Sildenafil	Sildenafil The metabolism of Sildenafil can be decreased when combined with Diltiazem.
Pioglitazone	Pioglitazone The metabolism of Pioglitazone can be decreased when combined with Diltiazem.
Celecoxib	Celecoxib The metabolism of Celecoxib can be decreased when combined with Diltiazem.
Rosiglitazone	Rosiglitazone The metabolism of Rosiglitazone can be decreased when combined with Diltiazem.
Tolterodine	Tolterodine The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Diltiazem.
Thalidomide	Thalidomide The metabolism of Diltiazem can be increased when combined with Thalidomide.
Balsalazide	Balsalazide The risk or severity of bleeding can be increased when Diltiazem is combined with Balsalazide.
Nateglinide	Nateglinide The metabolism of Nateglinide can be decreased when combined with Diltiazem.
Galantamine	Galantamine The risk or severity of QTc prolongation can be increased when Galantamine is combined with Diltiazem.
Rabeprazole	Rabeprazole The metabolism of Diltiazem can be decreased when combined with Rabeprazole.
Terbinafine	Terbinafine The metabolism of Terbinafine can be decreased when combined with Diltiazem.

* This branded product is no longer on the market. Generic alternatives may be available.

Diltiazem

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