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Aliskiren

Aliskiren is a prescription blood pressure medicine (sold as Tekturna and generic aliskiren) used to treat high blood pressure in adults and certain children.

Brand name Tekturna
Drug class Renin Inhibitors
Rx Form 1
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026 Content updated Oct 2, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 3 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

✓No current FDA shortage listed · checked Oct 5, 2026
Aliskiren at a glance The quick version — the full detail is in the Patient Information Guide below.
Dr. Brian Staiger, PharmD, BCPS
The Pharmacist’s Take By · Clinical pharmacist · Written

Aliskiren (Tekturna) is a once-daily medicine that treats high blood pressure by blocking renin, the first step in the body's blood pressure-raising system. It has been on the market since about 2007, is available as a generic, and is usually not a first choice. Most people tolerate it well, and diarrhea, more likely at higher doses, is the side effect people notice most. Its boxed warning covers pregnancy, because it can seriously harm or kill an unborn baby, so stop it and call your prescriber as soon as you learn you are pregnant.

Clinical pearls

  • Keep meals consistent, always with food or always without, and avoid taking it right after a high-fat meal, which sharply cuts absorption.
  • Combining it with lisinopril, valsartan or similar drugs raises potassium and kidney risks, and the combination is off-limits with diabetes.
  • Ibuprofen or naproxen can blunt its effect and strain the kidneys, especially in older adults or people on a water pill.
  • Tell any prescriber you take it before starting the antifungal itraconazole or cyclosporine, which push aliskiren levels much higher.
How we write & review this content — our editorial policy →
⚠️ FDA Boxed Warning — the FDA’s strongest safety alert ▾

WARNING: Aliskiren can cause serious harm or death to an unborn baby. If you find out you are pregnant while taking aliskiren, stop taking it as soon as possible and call your doctor right away. Medicines that work on the renin-angiotensin system — the body's blood pressure control pathway — can damage or destroy a developing baby's kidneys and cause death, particularly during the second and third trimesters of pregnancy. Use effective birth control while on this medication and act immediately if pregnancy occurs.

Read the full warning on DailyMed →
How you get itPrescription only
Comes asTablet
Earliest FDA record2007
Companies listing it with the FDA3
FDA label last updatedDec 30, 2022
FDA’s strongest warning (boxed)Yes, read the warning

Patient information guide A plain-language walkthrough of Aliskiren, written from its FDA label.

What Aliskiren is used for

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Aliskiren is used to treat high blood pressure (hypertension). Both branded and generic tablet forms are approved for this use.

  • Tekturna (film-coated tablet, oral) is indicated for high blood pressure in adults and in children who are at least 6 years old and weigh 50 kg (about 110 lbs) or more.
  • Aliskiren tablets (generic, oral) carry the same indication — high blood pressure in adults and qualifying pediatric patients.
  • Lowering blood pressure reduces the risk of stroke and heart attack.
  • Blood pressure control works best as part of a full plan: healthy lifestyle, managing cholesterol, blood sugar, and other heart risk factors.
  • Many patients need more than one medicine to reach blood pressure goals.

How Aliskiren works

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Aliskiren is a direct renin inhibitor. Renin is an enzyme the kidneys release to kick off a chain reaction — the renin-angiotensin-aldosterone system (RAAS) — that ultimately tightens blood vessels and raises blood pressure. By blocking renin at the very start of that chain, aliskiren prevents the production of angiotensin I and angiotensin II, the substances that cause blood vessels to constrict. With less angiotensin II around, blood vessels relax and blood pressure falls.

Unlike ACE inhibitors and ARBs (which block the RAAS further down the chain), aliskiren blocks the compensatory rise in renin activity, so plasma renin activity, angiotensin I, and angiotensin II are all reduced during treatment.

Aliskiren dosage

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Aliskiren tablets are taken once daily by mouth. The medicine starts working within a couple of weeks, and most of its blood pressure effect at a given dose is reached by about 2 weeks. It's important to pick a consistent routine with regard to meals — either always with food or always without — and stick to it every day.

  • High-fat meals can sharply reduce absorption, so avoid eating a fatty meal right before your dose.
  • If your blood pressure isn't controlled enough, your prescriber may increase the dose — but do not change your dose on your own.
  • Always follow your prescriber's instructions and your prescription label.

Dosing details from the FDA-approved label

From the Aliskiren prescribing information (“Dosage and Administration”). Doses are set by your prescriber for your product, condition, kidney function and age — never change a dose on your own.

  • Adult patients and pediatric patients weighing 50 kg or greater who are at least 6 years of age (hypertension)
    • Recommended starting dose 150 mg once daily
    • If blood pressure is not adequately controlled, the daily dose may be increased to 300 mg once daily
    • Maximum: 300 mg once daily (doses above 300 mg did not give an increased blood pressure response but resulted in an increased rate of diarrhea)
    • Establish a routine pattern for taking with regard to meals; high-fat meals decrease absorption substantially; 85% to 90% of the antihypertensive effect is attained by 2 weeks
Read the label’s full dosing text

2 DOSAGE AND ADMINISTRATION Starting dose (adults and pediatric patients): 150 mg once daily with a routine pattern with regard to meals. If blood pressure remains uncontrolled titrate up to 300 mg daily. ( 2.1 ) Majority of effect of given dose attained in 2 weeks ( 2.1 ) 2.1 Recommended Dosage In adult patients and in pediatric patients weighing 50 kg or greater who are at least 6 years of age, the recommended starting dose of aliskiren tablets is 150 mg once daily. In patients whose blood pressure is not adequately controlled, the daily dose may be increased to 300 mg once daily. Doses above 300 mg did not give an increased blood pressure response but resulted in an increased rate of diarrhea. The antihypertensive effect of a given dosage is substantially attained (85% to 90%) by 2 weeks. 2.2 Relationship to Meals Patients should establish a routine pattern for taking aliskiren tablets with regard to meals. High-fat meals decrease absorption substantially [ see Clinical Pharmacology (12.3) ].

Read the full Dosage and Administration section on DailyMed →

Aliskiren side effects

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The most common side effect of aliskiren is diarrhea, which tends to be mild and is more likely at higher doses. Women and adults 65 and older may notice it even at lower doses.

Common side effects

  • Diarrhea (most common; more likely at higher doses)
  • Abdominal (stomach) pain
  • Upset stomach or indigestion
  • Cough (mild)
  • Rash
  • Swelling of the face, hands, or body
  • Nausea or vomiting
  • Elevated uric acid levels (which can trigger gout)

When to get medical help

  • Get emergency help if you have swelling of the face, lips, tongue, or throat (angioedema), or trouble breathing — this can be life-threatening
  • Call your doctor right away if you feel faint, dizzy, or have a sudden drop in blood pressure
  • Stop taking aliskiren and call your doctor immediately if you become pregnant
  • Tell your doctor if you notice decreased urination, muscle weakness, or an irregular heartbeat — signs of high potassium or kidney problems
  • Seek medical help for severe skin reactions such as blistering, peeling, or widespread rash
  • Tell your doctor if you notice yellowing of the skin or eyes, or other signs of liver problems

Seek emergency help immediately for severe allergic reactions — especially swelling of the face, tongue, or throat (angioedema) or trouble breathing. Also contact your doctor if you notice signs of high potassium (muscle weakness, irregular heartbeat), worsening kidney function (reduced urination), or severe skin reactions such as blistering or peeling.

Aliskiren warnings and precautions

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  • Fetal harm (boxed warning): Aliskiren can cause serious injury or death to an unborn baby. Stop it immediately if you become pregnant and contact your doctor.
  • Angioedema: Rare but potentially life-threatening swelling of the face, lips, tongue, or throat can occur. Get emergency care immediately if this happens.
  • Low blood pressure (hypotension): Risk is higher if you are dehydrated, on diuretics, or combining aliskiren with other blood pressure medicines. Dizziness or fainting are warning signs.
  • High potassium (hyperkalemia): Can occur, especially when combined with ACE inhibitors or ARBs. Report muscle weakness or irregular heartbeat.
  • Kidney function changes: Aliskiren combined with ACE inhibitors or ARBs — particularly in patients with kidney disease — can worsen kidney function or cause acute kidney failure.
  • Severe skin reactions: Rare cases of Stevens-Johnson syndrome and toxic epidermal necrolysis (serious blistering skin conditions) have been reported after marketing.

Aliskiren interactions

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Aliskiren interacts with several important medicines and substances. Tell your prescriber and pharmacist about everything you take.

  • ACE inhibitors and ARBs (e.g., lisinopril, ramipril, valsartan) — combining these with aliskiren raises the risk of low blood pressure, high potassium, and kidney damage; this combination is contraindicated (forbidden) in patients with diabetes.
  • Cyclosporine — can greatly increase aliskiren levels in the blood; avoid this combination.
  • Itraconazole (antifungal) — can greatly increase aliskiren levels; avoid combining.
  • NSAIDs (ibuprofen, naproxen, COX-2 inhibitors) — can weaken aliskiren's blood pressure effect and increase kidney damage risk, especially in older adults or people on diuretics.
  • Furosemide (water pill) — aliskiren can reduce furosemide's effectiveness; monitor for fluid retention or reduced diuretic response.
  • High-fat meals — sharply reduce aliskiren absorption; maintain a consistent meal routine daily.

Interactions listed in the FDA-approved label

From the Aliskiren prescribing information (“Drug Interactions”): what the manufacturer studied or reported to the FDA.

  • Cyclosporine: The label advises avoiding coadministration with aliskiren. Avoid coadministration
  • Itraconazole: The label advises avoiding coadministration with aliskiren. Avoid coadministration
  • Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) including selective COX-2 inhibitors: In elderly, volume-depleted (including those on diuretic therapy) or renally compromised patients, coadministration may result in deterioration of renal function, including possible acute renal failure, usually reversible; the antihypertensive effect of aliskiren may be attenuated by NSAIDs. Monitor renal function periodically in patients receiving aliskiren and NSAID therapy
  • Dual blockade of the RAAS (ACE inhibitors or ARBs): Concomitant use is associated with an increased risk of hypotension, hyperkalemia, and changes in renal function (including acute renal failure) compared to monotherapy; most patients do not obtain additional benefit compared to monotherapy. In general avoid combined use, particularly in patients with CrCl less than 60 mL/min; monitor blood pressure, renal function, and electrolytes; use with an ARB or ACEI in diabetic patients is contraindicated
  • Furosemide: Oral coadministration of aliskiren and furosemide reduced exposure to furosemide. Monitor diuretic effects when furosemide is coadministered with aliskiren
Read the label’s full interactions text

7 DRUG INTERACTIONS Cyclosporine: Avoid coadministration of cyclosporine with aliskiren [see Warnings and Precautions ( 5.7 ) and Clinical Pharmacology ( 12.3 )] . Itraconazole: Avoid coadministration of itraconazole with aliskiren [see Warnings and Precautions ( 5.7 ) and Clinical Pharmacology ( 12.3 )]. Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) including selective Cyclooxygenase-2 inhibitors (COX-2 inhibitors): In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors with agents that affect the RAAS, including aliskiren, may result in deterioration of renal function, including possible acute renal failure. These effects are usually reversible. Monitor renal function periodically in patients receiving aliskiren and NSAID therapy. The antihypertensive effect of aliskiren may be attenuated by NSAIDs. Dual Blockade of the Renin-Angiotensin-Aldosterone System (RAAS): The concomitant use of aliskiren with other agents acting on the RAAS such as ACEIs or ARBs is associated with an increased risk of hypotension, hyperkalemia, and changes in renal function (including acute renal failure) compared to monotherapy. Most patients receiving the combination of two drugs that inhibit the renin-angiotensin system do not obtain any additional benefit compared to monotherapy. In general, avoid combined use of aliskiren with ACE inhibitors or ARBs, particularly in patients with CrCl less than 60 mL/min. Monitor blood pressure, renal function, and electrolytes in patients taking aliskiren and other agents that affect the RAAS [see Warnings and Precautions ( 5.4 , 5.5 , 5.6 )]. The concomitant use of aliskiren with an ARB or an ACEI in diabetic patients is contraindicated [see Contraindications ( 4 )]. Furosemide: Oral coadministration of aliskiren and furosemide reduced exposure to furosemide.

Excerpted — the section continues on the label. Read the full Drug Interactions section on DailyMed →

Not a complete list. The label covers the interactions the manufacturer studied or reported, and our own interaction database does not cover every medicine either. Bring your full medication list, including vitamins and herbal products, to your pharmacist.

🌿227 supplements and herbs with documented Aliskiren interactions, ranked by severity Check Aliskiren against a supplement or herb →

Before taking Aliskiren

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  • Pregnancy: Do not take aliskiren if you are pregnant. Stop immediately if you become pregnant and call your doctor.
  • Breastfeeding: Breastfeeding is not recommended while taking aliskiren due to the potential for serious side effects in nursing infants.
  • Diabetes + ACE inhibitor or ARB: Do not take aliskiren if you have diabetes and are already on an ACE inhibitor or ARB — this combination is contraindicated.
  • Kidney disease: Use with caution; combining aliskiren with ACE inhibitors or ARBs when kidney function is reduced (creatinine clearance below 60 mL/min) is especially risky.
  • Known allergy: Do not take aliskiren if you have had a serious allergic reaction (including angioedema) to any of its ingredients.
  • Children under 2 years old: Aliskiren tablets are contraindicated in this age group.
  • Children 2 to under 6 years, or under 20 kg: Safety and effectiveness have not been established; avoid use.
  • Children 6 and older weighing 20–49 kg: Although aliskiren has shown effectiveness in this group, the tablet form is not approved because no appropriate dosage form exists for this weight range.
  • Liver disease: Aliskiren pharmacokinetics are not significantly affected by mild to severe liver disease; no starting dose adjustment is required, but tell your doctor about any liver conditions.

Aliskiren overdose

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There is limited information about aliskiren overdose in people. The most likely result of taking too much would be a dangerous drop in blood pressure (hypotension) — signs include dizziness, fainting, or feeling very weak. If you or someone else may have taken too much, seek emergency medical help right away. Aliskiren is poorly removed by hemodialysis (kidney dialysis), so dialysis is not an effective way to treat an overdose.

What Aliskiren does in the body

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In clinical trials, aliskiren reduced plasma renin activity (PRA — a measure of how active the renin system is in the blood) by 50% to 80%. This reduction was not directly tied to the size of the dose and did not directly predict how much blood pressure would fall. The full clinical meaning of these PRA changes is not entirely understood, but the overall effect is a reduction in the hormones that drive blood pressure up.

How your body processes Aliskiren

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Aliskiren is poorly absorbed from the gut — only about 2.5% of each dose actually reaches the bloodstream. After taking a tablet, peak blood levels are reached within 1 to 3 hours, and steady, stable levels in the body are achieved after about 7 to 8 days of daily dosing. The body's half-life for accumulating aliskiren is approximately 24 hours, making once-daily dosing effective. A high-fat meal can reduce absorption dramatically (by up to 71–85%), so consistency with meals matters. A portion of the absorbed drug is cleared through urine unchanged, and the main enzyme involved in its metabolism is CYP3A4. Aliskiren does not significantly affect how the body handles most other drugs metabolized by the CYP450 system.

How to store Aliskiren

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Store at 20°C to 25ºC (68°F to 77ºF); excursions permitted to 15ºC to 30ºC (59 ºF to 86ºF) . Protect from moisture.

Written from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

227

Supplements & herbs that interact with Aliskiren

227 supplements and herbal products have documented interactions with Aliskiren in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.

Severity mix
  • Major · 6
  • Moderate · 180
  • Minor · 41
ACTIVATED CHARCOAL Major AMERICAN HELLEBORE Major AMERICAN MISTLETOE Major GRAPEFRUIT Major ST. JOHN'S WORT Major TYRAMINE Major ACACIA RIGIDULA Moderate ADRAFINIL Moderate +219 more
Every supplement checked against Aliskiren — ranked by severity The full interaction hub: 6 major · 180 moderate · 41 minor · every one linked to its full report. Check Aliskiren against your exact supplements

Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.

1

Nutrient depletion considerations

Aliskiren has been associated with lower levels of 1 nutrient in the clinical literature. This does not mean a deficiency will occur — it means these may be worth discussing with your pharmacist or healthcare provider, especially with long-term use.

COENZYME Q10 Insufficient Evidence
See the full Aliskiren nutrient depletion report

Educational information from a licensed clinical database (Natural Medicines) — not medical advice. Do not start or stop medications or supplements without professional guidance.

Aliskiren: pharmacist answers to common questions

Quick, plain-English answers to the questions patients ask most about Aliskiren — the kind of thing our pharmacy team would talk through with you at the counter.

What exactly is aliskiren (Tekturna) used for?

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Aliskiren is used to lower high blood pressure — that's its one approved use. By controlling your blood pressure, it helps reduce your risk of serious events like stroke and heart attack. It comes as a tablet you take once a day, and it's approved for adults as well as children 6 years and older who weigh at least 50 kg (about 110 lbs).

Does it matter whether I take it with food or on an empty stomach?

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What matters most is being consistent. Pick a routine — always with a light meal, always without food, whatever works for you — and stick to it every day. The one thing to avoid is taking it right after a high-fat meal, like a big greasy breakfast, because fatty food can dramatically reduce how much of the medicine your body absorbs. High-fat meals can cut absorption by more than 70%, so that's a real concern.

What side effects should I watch out for?

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The most common one is diarrhea, which tends to be mild and more likely at higher doses. Some people notice stomach discomfort, a mild cough, or a rash. Those are manageable. What I really want you to call us or go to the ER for is any swelling of your face, lips, tongue, or throat, or difficulty breathing — that can be a serious allergic reaction called angioedema and needs emergency care immediately. Also call your doctor if you feel faint, notice much less urination than usual, or feel muscle weakness.

I'm also taking ibuprofen for joint pain — is that okay?

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You should check with your doctor before taking ibuprofen or other NSAIDs (like naproxen) regularly with aliskiren. Using them together can weaken aliskiren's blood pressure effect and raise the risk of kidney problems — especially if you're older, on a diuretic (water pill), or already have some kidney issues. There may be safer pain options your doctor can suggest.

What if I find out I'm pregnant while taking this medicine?

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Stop taking aliskiren as soon as you find out and contact your doctor right away. This is very important — aliskiren can cause serious kidney damage or death to a developing baby, especially in the second and third trimesters. Your doctor will work with you to find a safe alternative to manage your blood pressure during pregnancy. If you are planning to become pregnant, talk to your doctor before you start trying.

I'm already on lisinopril for my blood pressure — can I add aliskiren?

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Not if you have diabetes. Combining aliskiren with an ACE inhibitor like lisinopril is actually contraindicated (not allowed) in people with diabetes because it significantly increases the risk of low blood pressure, high potassium levels, and kidney damage. Even without diabetes, adding aliskiren to an ACE inhibitor or ARB carries extra risks and should generally be avoided — especially if your kidney function is reduced. Your prescriber will weigh the risks carefully before considering any combination.

Is Aliskiren available over the counter?

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No. Aliskiren is a prescription medicine: every Aliskiren product listed with the FDA is prescription only, so it is not sold over the counter. Your prescriber decides whether it is appropriate for you, and your pharmacist dispenses it.

When was Aliskiren first available?

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The earliest FDA record we hold for Aliskiren is from 2007: its first approval in Drugs@FDA or its earliest product listing in the NDC Directory, whichever is older. Many older medicines were in use before their first formal FDA approval, so this is the earliest date on record, not necessarily when Aliskiren was first used.

Who makes Aliskiren?

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3 companies currently list Aliskiren products in the FDA's NDC Directory, including LXO US Inc., Par Health USA, LLC, Prasco Laboratories. That count includes repackagers and distributors as well as manufacturers (companies that sell only the raw ingredient are not counted), so fewer companies actually make it; the label on your bottle names the one that supplied yours.

Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

More about Aliskiren on HelloPharmacist

📊Aliskiren supplement interactions227 checked — ranked by severity 🌿Drug & Supplement CheckerAliskiren vs. vitamins & herbs 💬Ask a PharmacistFree answer, usually < 24h 🔎NDC & pricing lookupFind Aliskiren NDCs & costs 🅰️Browse Drugs A–ZLook up any medication
Detailed data & references for Aliskiren Forms & strengths, pricing, billing codes, manufacturers, safety reports and sourcing — the data behind the page. Most people can stop here. Each section below opens on a tap.

Aliskiren forms and strengths (how it comes)

Aliskiren is available in 1 form. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Tablet

By mouth
Brands Tekturna
How this form is used
What it may be used for
  • Tekturna (film-coated tablet) is indicated to treat high blood pressure in adults and in children at least 6 years old weighing 50 kg or more
  • Aliskiren tablets are indicated to treat high blood pressure in adults and in children at least 6 years old weighing 50 kg or more
Important instructions
  • Tekturna is taken once daily by mouth; establish a consistent routine with regard to meals and stick to it
  • Aliskiren tablets are taken once daily by mouth; keep a consistent meal routine each day
  • Avoid taking either product right after a high-fat meal — fatty food can drastically reduce how much medicine is absorbed
  • Most of the blood pressure effect of a given dose is reached within about 2 weeks of starting or changing the dose
Available strengths 2 strengths
150 mg 300 mg
16 FDA-listed product records ⓘ

Aliskiren on the U.S. market: products, makers and brands

How Aliskiren appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

3 companies list 6 Aliskiren product records with the FDA, mostly as tablet; the earliest marketing or approval year on record is 2007. Brand names on the directory include Tekturna; the rest are generics.

1
Dose forms ⓘ
3
Labelers (makers, repackagers, distributors)
2
Brand names
6
FDA-listed product records ⓘ
2007
Earliest FDA record ⓘ

Also listed with the FDA, not a patient dose form: Powder (3) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

LXO US Inc.33%
Par Health USA, LLC33%
Prasco Laboratories33%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

How widely Aliskiren is used (Medicaid data)

A general measure of how commonly Aliskiren is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Aliskiren is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

119
Medicaid prescriptions filled (Q1–Q4 2025)
$28,990 gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Aliskiren prescribed? Of the 1,601 medications we measure, Aliskiren ranks #1,489 by Medicaid prescriptions — more than 7% of them.

Where Aliskiren ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5
Total prescriptions — #1,489 of 1,601
#1,484 Ixazomib 125 Rx #1,485 Mitapivat 125 Rx #1,486 Mirikizumab-Mrkz 123 Rx #1,487 Pamidronate Injection 121 Rx #1,488 Romidepsin Injection 120 Rx #1,489 Aliskiren 119 Rx #1,490 Miglustat 118 Rx #1,491 Mechlorethamine Topica... 118 Rx #1,492 Mechlorethamine 118 Rx #1,493 Tezacaftor and Ivacaft... 114 Rx #1,494 Monomethyl Fumarate 114 Rx

Utilization by Aliskiren product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

The 300 mg oral tablet is the most-dispensed Aliskiren product — about 76% of these Medicaid prescriptions.

aliskiren 300 MG Oral Tablet Most dispensed

91 Medicaid prescriptions (Q1–Q4 2025) 76% of Aliskiren prescriptions shown $22,138 gross reimbursement (before rebates) ≈ $243 per prescription (gross)

Summed across the 2 of 3 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1011739

aliskiren 150 MG Oral Tablet

28 Medicaid prescriptions (Q1–Q4 2025) 24% of Aliskiren prescriptions shown $6,852 gross reimbursement (before rebates) ≈ $245 per prescription (gross)

Summed across the 1 of 3 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1011736

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Aliskiren, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 3 of 6 listed Aliskiren NDCs with Medicaid activity.

Compare Aliskiren products

A representative set of FDA-listed product records for Aliskiren — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Strength Route Manufacturer / Labeler Category ⓘ Details
💊Tablet
150 mg Oral LXO US Inc. NDA View NDC →
300 mg Oral LXO US Inc. NDA View NDC →
150 mg Oral Par Health USA, LLC ANDA View NDC →
300 mg Oral Par Health USA, LLC ANDA View NDC →
150 mg Oral Prasco Laboratories NDA AUTHORIZED GENERIC View NDC →
300 mg Oral Prasco Laboratories NDA AUTHORIZED GENERIC View NDC →

Showing 6 of 6 products — FDA National Drug Code Directory. See every product, package size and price: browse all 6 Aliskiren NDCs →

Aliskiren recall history

A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.

The FDA’s enforcement reports list no Aliskiren recalls since July 2021.

✅No Aliskiren recalls on record since July 2021

Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Sep 24, 2026.

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Aliskiren RxCUI 325646 1 dose form · 2 strengths
  1. Dose form (SCDF) Oral Tablet RxCUI 692500 In current FDA listings
    Clinical drug / strength (SCD) 150 MG RxCUI 1011736 300 MG RxCUI 1011739

Look up RxCUI 325646 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

💵 What Aliskiren costs pharmacies (NADAC benchmark)

The national average invoice price pharmacies pay for the drug itself, from CMS's NADAC survey (data as of Sep 30, 2026). This is a supply-cost benchmark — not a retail price and not what you'd pay at the counter.

FormStrengthPharmacy acquisition benchmark
Tablet, Film Coated · Oral 150 mg $3.94 per tablet NDC details & price history
Tablet, Film Coated · Oral 300 mg $5.86 per tablet NDC details & price history
Why show this? Your out-of-pocket cost depends on insurance, pharmacy markup, and discounts — but the acquisition benchmark tells you whether the medication itself is inexpensive or costly, which strengths cost more per dose, and whether a cash-price quote is in a reasonable range. Each row links to the NDC-level record with its full price history.

Source: CMS National Average Drug Acquisition Cost (NADAC), a survey of retail pharmacy invoice prices. Benchmarks shown are the range across package sizes of a representative product for each form and strength — other manufacturers' products may differ.

Aliskiren brand names

Aliskiren is sold under one brand name in the FDA directory — Tekturna. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.

Tekturna

Who makes Aliskiren: manufacturers and labelers

3 companies list Aliskiren products with the FDA. By number of product records, the largest are LXO US Inc., Par Health USA, LLC, Prasco Laboratories. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.

LXO US Inc. 2 Par Health USA, LLC 2 Prasco Laboratories 2

Aliskiren drug class (RxNorm)

Aliskiren belongs to the Renin Inhibitor class.

Pharmacologic class Renin Inhibitor
Drug family (ATC) Renin-inhibitors
How it works Renin Inhibitors

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

Sources for this Aliskiren page

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

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FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Dec 30, 2022
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Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Aliskiren.
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Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
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Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Aliskiren after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
3
Finished products in the current FDA directory
6
Companies listing them (makers, repackagers, distributors)
3
FDA labeler codes behind them ⓘ
3
Linked representative label ⓘ
Par Pharmaceutical, Inc.
Linked label effective
Dec 30, 2022
Composite sections available
22
Linked SPL Set ID
f3fd2503-25ef-4660-a29a-f62c491e28fb
Linked SPL Document ID
640e0067-1ca8-4509-9b69-0f525caca6de
Open the linked representative label on DailyMed ↗

How this page is built

HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. Par Pharmaceutical, Inc. is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →