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Furosemide

Furosemide is a loop diuretic (“water pill”) used to treat edema (fluid buildup) from heart failure, liver cirrhosis and kidney disease, and, in oral forms, to treat high blood pressure.

Brand names LasixDisalFuroscixSalix - substanceLasix Onyu
Drug class Loop Diuretic
Rx Forms 3
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026 Content updated Oct 2, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 108 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

Other forms & routes:
Furosemide at a glance The quick version — the full detail is in the Patient Information Guide below.
Dr. Brian Staiger, PharmD, BCPS
The Pharmacist’s Take By · Clinical pharmacist · Written

Furosemide (Lasix) is a loop diuretic, a strong “water pill” that stops the kidneys from reabsorbing salt so salt and water leave in the urine, and it is the most widely used drug for fluid buildup from heart failure, cirrhosis and kidney disease (it also treats high blood pressure), on the market since about 1966 and available as a generic. Most people handle it well, mainly noticing frequent urination soon after each dose and lightheadedness when standing up. Its boxed warning is that too much can drain water and body salts (electrolytes) dangerously, so report severe dizziness, fainting, extreme weakness, very little urine or any ringing in the ears right away.

Clinical pearls

  • Take it in the morning, and any second dose by mid-afternoon, so the extra urination does not keep you up at night.
  • Expect regular blood tests for potassium, sodium and kidney function, because furosemide flushes out body salts along with the water.
  • If you take lithium, make sure every prescriber knows, since furosemide can push lithium to toxic levels.
  • Weigh yourself each morning, because a quick gain or drop shows whether the dose is pulling off too little fluid or too much.
How you get itPrescription only
Comes asTablet, Injection, Oral solution
Earliest FDA record1966
Companies listing it with the FDA59
FDA label last updatedNov 3, 2025
FDA’s strongest warning (boxed)None on the label

Patient information guide A plain-language walkthrough of Furosemide, written from its FDA label.

What Furosemide is used for

▾

Furosemide treats fluid buildup and, in oral forms, high blood pressure. Uses vary by product.

  • Edema from congestive heart failure, cirrhosis of the liver, and kidney disease including nephrotic syndrome: Lasix, furosemide tablets, oral solution and injection (adults and children).
  • High blood pressure in adults, alone or with other medicines: oral furosemide and Lasix tablets.
  • Add-on treatment for acute pulmonary edema: furosemide injection.
  • Edema in adults with chronic heart failure or chronic kidney disease, and in children 43 kg and above: Furoscix, subcutaneous.
  • Edema in adults with chronic heart failure: Lasix Onyu, subcutaneous.

How Furosemide works

▾

Furosemide acts on the kidney’s filtering tubes, mainly the loop of Henle. It blocks reabsorption of sodium and chloride, so more salt and water leave in the urine. Its action on the distal tubule does not depend on carbonic anhydrase or aldosterone.

Furosemide dosage

▾

Dosing is tailored to your response, aiming for the lowest dose that keeps swelling controlled.

  • Tablets and oral solution: swallowed, usually once or twice daily. Some people use them only on certain days each week.
  • Injection: given IV or IM only when you cannot take oral medicine or in emergencies, then switched to oral.
  • Furoscix and Lasix Onyu: given under the skin and not for long-term use.

Follow your prescriber and product label.

Dosing details from the FDA-approved label

From the Furosemide prescribing information (“Dosage and Administration”). Doses are set by your prescriber for your product, condition, kidney function and age — never change a dose on your own.

  • Adult Patients: FUROSCIX ReadyFlow (autoinjector)
    • Delivers 80 mg of furosemide subcutaneously in about 10 seconds
    • Not for chronic use; should be replaced with oral diuretics as soon as practical
  • Adult and Pediatric Patients 43 kg and Above: On-body Infusor for FUROSCIX
    • Pre-programmed to deliver 30 mg of furosemide subcutaneously over the first hour followed by 12.5 mg per hour for the subsequent 4 hours
    • In pediatric patients weighing at least 43 kg, must be administered by a healthcare provider or adult caregiver
  • Lasix ONYU (Infusor with single-dose prefilled cartridge), edema
    • 30 mg over the first hour followed by 12.5 mg per hour for the subsequent 4 hours
    • Administer once or twice daily as needed for edema
    • Not for chronic use; should be replaced with oral diuretics as soon as practical
Read the label’s full dosing text

DOSAGE AND ADMINISTRATION Edema Therapy should be individualized according to patient response to gain maximal therapeutic response and to determine the minimal dose needed to maintain that response. Adults - The usual initial dose of furosemide tablets is 20 to 80 mg given as a single dose. Ordinarily a prompt diuresis ensues. If needed, the same dose can be administered 6 to 8 hours later or the dose may be increased. The dose may be raised by 20 or 40 mg and given not sooner than 6 to 8 hours after the previous dose until the desired diuretic effect has been obtained. The individually determined single dose should then be given once or twice daily (e.g., at 8 am and 2 pm). The dose of furosemide tablets may be carefully titrated up to 600 mg/day in patients with clinically severe edematous states. Edema may be most efficiently and safely mobilized by giving furosemide tablets on 2 to 4 consecutive days each week. When doses exceeding 80 mg/day are given for prolonged periods, careful clinical observation and laboratory monitoring are particularly advisable (see PRECAUTIONS: Laboratory Tests ). Geriatric Patients - In general, dose selection for the elderly patient should be cautious, usually starting at the low end of the dosing range (see PRECAUTIONS: Geriatric Use ). Pediatric Patients - The usual initial dose of oral furosemide in pediatric patients is 2 mg/kg body weight, given as a single dose. If the diuretic response is not satisfactory after the initial dose, dosage may be increased by 1 or 2 mg/kg no sooner than 6 to 8 hours after the previous dose. Doses greater than 6 mg/kg body weight are not recommended. For maintenance therapy in pediatric patients, the dose should be adjusted to the minimum effective level. Hypertension Therapy should be individualized according to the patient's response to gain maximal therapeutic response and to determine the minimal dose needed to maintain the therapeutic response. Adults - The usual initial dose of furosemide tablets for hypertension is 80 mg, usually divided into 40 mg twice a day. Dosage should then be adjusted according to response. If response is not satisfactory, add other antihypertensive agents. Changes in blood pressure must be carefully monitored when furosemide tablets are used with other antihypertensive drugs, especially during initial therapy.

Excerpted — the section continues on the label. Read the full Dosage and Administration section on DailyMed →

Furosemide side effects

▾

Most side effects are related to fluid loss or the stomach.

Common side effects

  • Nausea, vomiting or diarrhea
  • Constipation or stomach cramping
  • Dizziness, vertigo or headache
  • Low blood pressure when standing up
  • Muscle spasm or weakness
  • Rash or sensitivity to sunlight
  • Blurred vision
  • Skin redness, bruising, swelling or pain at the injection or infusion site
  • Rash or sun sensitivity

When to get medical help

  • Ringing in the ears, hearing loss or deafness: tell your doctor right away
  • Signs of dehydration or low fluid volume, such as severe dizziness, fainting or weakness
  • Severe allergic reaction, such as swelling, trouble breathing or shock
  • Severe skin reactions, such as blistering, peeling or widespread rash
  • Severe stomach pain, which can signal pancreatitis, or yellowing of skin or eyes
  • Unusual bruising, bleeding, fever or infections, which can signal blood problems
  • Trouble urinating, especially if you have an enlarged prostate or bladder emptying problems
  • Less urine than normal if you have severe kidney disease

Furosemide warnings and precautions

▾
  • Fluid and electrolyte loss: too much can cause dehydration, low blood pressure and blood clots, especially in older adults. Regular blood tests are needed.
  • Hearing damage: ringing, hearing loss and deafness have been reported, sometimes permanent.
  • Kidney function: furosemide may be stopped if kidney disease worsens.
  • Cirrhosis: sudden fluid shifts may trigger hepatic coma, so start in the hospital.
  • Urinary retention: possible if you have trouble emptying your bladder.

Furosemide interactions

▾

Furosemide can interact with many medicines.

  • Aminoglycoside antibiotics and ethacrynic acid: hearing damage risk
  • Lithium: can reach toxic levels
  • ACE inhibitors, ARBs and other blood pressure drugs: blood pressure may drop too far
  • Salicylates: toxicity at lower doses
  • Cisplatin and cephalosporins: kidney and hearing risks
  • Indomethacin and phenytoin: weaker furosemide effect
  • Methotrexate and similar drugs: levels may rise
  • Cyclosporine: higher gout risk
  • Chloral hydrate with IV furosemide: flushing, sweating, fast heartbeat

Interactions listed in the FDA-approved label

From the Furosemide prescribing information (“Drug Interactions”): what the manufacturer studied or reported to the FDA.

  • Aminoglycoside antibiotics: Furosemide may increase the ototoxic potential of aminoglycoside antibiotics, especially in the presence of impaired renal function. Avoid combination except in life-threatening situations.
  • Ethacrynic acid: Possibility of ototoxicity. Avoid concomitant use with ethacrynic acid.
  • Salicylates: May experience salicylate toxicity at lower doses because of competitive renal excretory sites. Monitor for symptoms of salicylate toxicity.
  • Cisplatin and nephrotoxic drugs: There is a risk of ototoxic effects if cisplatin and furosemide are given concomitantly; nephrotoxicity. Administer furosemide at lower doses and with positive fluid balance when used to achieve forced diuresis during cisplatin treatment. Monitor renal function.
  • Paralytic agents: Furosemide has a tendency to antagonize the skeletal muscle relaxing effect of tubocurarine and may potentiate the action of succinylcholine. Monitor for skeletal muscle effect.
  • Lithium: Furosemide reduces lithium's renal clearance and adds a high-risk of lithium toxicity. Avoid concomitant use with lithium.
  • Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers: May lead to severe hypotension and deterioration in renal function, including renal failure. Monitor for changes in blood pressure and renal function and interrupt or reduce the dosage of furosemide, angiotensin converting enzyme inhibitors, or angiotensin receptor blockers if needed.
  • Antihypertensive drugs: Furosemide may add to or potentiate the therapeutic effect of other antihypertensive drugs. Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed.
  • Adrenergic blocking drugs or peripheral adrenergic blocking drugs: Potentiation occurs. Monitor for changes in blood pressure and adjust the dose of adrenergic blocking drugs if needed.
  • Norepinephrine: Furosemide may decrease arterial responsiveness (vasoconstricting effect) to norepinephrine. Monitor blood pressure (or mean arterial pressure).
Read the label’s full interactions text

Drug Interactions Furosemide may increase the ototoxic potential of aminoglycoside antibiotics, especially in the presence of impaired renal function. Except in life-threatening situations, avoid this combination. Furosemide should not be used concomitantly with ethacrynic acid because of the possibility of ototoxicity. Patients receiving high doses of salicylates concomitantly with furosemide, as in rheumatic disease, may experience salicylate toxicity at lower doses because of competitive renal excretory sites. There is a risk of ototoxic effects if cisplatin and furosemide are given concomitantly. In addition, nephrotoxicity of nephrotoxic drugs such as cisplatin may be enhanced if furosemide is not given in lower doses and with positive fluid balance when used to achieve forced diuresis during cisplatin treatment. Furosemide has a tendency to antagonize the skeletal muscle-relaxing effect of tubocurarine and may potentiate the action of succinylcholine. Lithium generally should not be given with diuretics because they reduce lithium's renal clearance and add a high risk of lithium toxicity. Furosemide combined with angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers may lead to severe hypotension and deterioration in renal function, including renal failure. An interruption or reduction in the dosage of furosemide, angiotensin-converting enzyme inhibitors, or angiotensin receptor blockers may be necessary. Potentiation occurs with ganglionic or peripheral adrenergic blocking drugs. Furosemide may decrease arterial responsiveness to norepinephrine. However, norepinephrine may still be used effectively. Simultaneous administration of sucralfate and furosemide tablets may reduce the natriuretic and antihypertensive effects of furosemide. Patients receiving both drugs should be observed closely to determine if the desired diuretic and/or antihypertensive effect of furosemide is achieved.

Excerpted — the section continues on the label. Read the full Drug Interactions section on DailyMed →

Not a complete list. The label covers the interactions the manufacturer studied or reported, and our own interaction database does not cover every medicine either. Bring your full medication list, including vitamins and herbal products, to your pharmacist.

Before taking Furosemide

▾
  • Do not use Furoscix if you cannot make urine or are allergic to furosemide or its ingredients.
  • Do not use the Furoscix On-body Infusor if you are allergic to medical adhesives.
  • Tell your doctor about liver cirrhosis, kidney disease or bladder emptying problems.
  • Pregnancy: tell your doctor; observational data have not shown a clear risk of birth defects, but animal studies showed harm in rabbits.
  • Breastfeeding: furosemide is in breast milk and may lower milk production at higher doses.
  • Children: Furoscix On-body Infusor is for those 43 kg and above; Furoscix ReadyFlow has not been established for children.
  • Older adults: more likely to have fluid and electrolyte problems.

Furosemide overdose

▾

Too much furosemide causes dehydration, low blood volume, low blood pressure and electrolyte imbalances. Treatment is supportive: replacing lost fluid and electrolytes, with frequent monitoring. Hemodialysis does not speed up elimination.

What Furosemide does in the body

▾

After IV injection, diuresis (increased urine output) begins within 5 minutes, and later after IM injection. The effect peaks within the first half hour and lasts about 2 hours. For Furoscix, the effect lasts up to 6 hours with the ReadyFlow and up to 8 hours with the On-body Infusor.

How your body processes Furosemide

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Furosemide binds heavily to blood proteins, mainly albumin. Its half-life is about 2 hours. The body mainly clears it unchanged in urine, with glucuronide as the main metabolite. More is excreted in urine after IV injection than after tablets or oral solution. In older adults, albumin binding and kidney clearance are reduced, and the initial diuretic effect is weaker.

How to store Furosemide

▾

Store at 68° to 77°F (20° to 25°C); excursions permitted to 59° to 86°F (15° to 30°C) .

Written from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

227

Supplements & herbs that interact with Furosemide

227 supplements and herbal products have documented interactions with Furosemide in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.

Severity mix
  • Major · 9
  • Moderate · 193
  • Minor · 25
Every supplement checked against Furosemide — ranked by severity The full interaction hub: 9 major · 193 moderate · 25 minor · every one linked to its full report. Check Furosemide against your exact supplements

Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.

9

Nutrient depletion considerations

Furosemide has been associated with lower levels of 9 nutrients in the clinical literature. This does not mean a deficiency will occur — it means these may be worth discussing with your pharmacist or healthcare provider, especially with long-term use.

Evidence & significance mix
  • Higher significance · 3
  • Moderate · 3
  • Unrated · 3
See the full Furosemide nutrient depletion report

Educational information from a licensed clinical database (Natural Medicines) — not medical advice. Do not start or stop medications or supplements without professional guidance.

Furosemide: pharmacist answers to common questions

Quick, plain-English answers to the questions patients ask most about Furosemide — the kind of thing our pharmacy team would talk through with you at the counter.

What is furosemide for?

▾
It helps your body get rid of extra fluid. It is used for swelling from heart failure, liver cirrhosis and kidney disease. In adults, oral forms can also treat high blood pressure.

How should I take it?

▾
Tablets and oral solution are swallowed, usually once or twice a day, or on certain days of the week if your doctor says so. Injected forms are for short-term use and are switched to oral as soon as practical. Follow your prescriber’s directions exactly.

What side effects are normal, and what should I call about?

▾
Dizziness, stomach upset, headache and more frequent urination can happen. Call your doctor right away for ringing in the ears, hearing loss, fainting, severe weakness, little urine, severe stomach pain, a severe rash or allergic reaction.

Why do I need blood tests?

▾
Furosemide can lower potassium, sodium and other electrolytes and affect kidney function and blood sugar. Regular blood tests let your doctor catch problems early and adjust your dose.

Can I take it with my other medicines?

▾
Many medicines interact, so tell me everything you take. Be especially careful with aminoglycoside antibiotics, lithium, blood pressure medicines, aspirin-type drugs, and methotrexate. Do not start anything new without checking.

Is it safe in pregnancy?

▾
Studies in people have not shown a clear risk of birth defects or miscarriage, but animal studies showed harm in rabbits. Untreated heart failure and cirrhosis are also risky in pregnancy. Talk to your doctor about weighing the benefits and risks.

Is Furosemide available over the counter?

▾
No. Furosemide is a prescription medicine: every Furosemide product listed with the FDA is prescription only, so it is not sold over the counter. Your prescriber decides whether it is appropriate for you, and your pharmacist dispenses it.

When was Furosemide first available?

▾
The earliest FDA record we hold for Furosemide is from 1966: its first approval in Drugs@FDA or its earliest product listing in the NDC Directory, whichever is older. Many older medicines were in use before their first formal FDA approval, so this is the earliest date on record, not necessarily when Furosemide was first used.

Who makes Furosemide?

▾
59 companies currently list Furosemide products in the FDA's NDC Directory, including A-S Medication Solutions, Bryant Ranch Prepack, Hikma Pharmaceuticals USA Inc.. That count includes repackagers and distributors as well as manufacturers (companies that sell only the raw ingredient are not counted), so fewer companies actually make it; the label on your bottle names the one that supplied yours.

Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

More about Furosemide on HelloPharmacist

Detailed data & references for Furosemide Forms & strengths, pricing, billing codes, manufacturers, safety reports and sourcing — the data behind the page. Most people can stop here. Each section below opens on a tap.

Furosemide forms and strengths (how it comes)

Furosemide is available in 3 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Need a version that does not list lactose, a gluten source, a dye or gelatin? Inactive ingredients differ by manufacturer: see Furosemide inactive ingredients by manufacturer.

Tablet

By mouth
Brands Lasix
How this form is used
What it may be used for
  • Lasix and furosemide tablets treat edema from congestive heart failure, cirrhosis and kidney disease, in adults and children.
  • Lasix and furosemide tablets may be used in adults for high blood pressure, alone or with other medicines.
Important instructions
  • Lasix and furosemide tablets are dosed individually, usually once or twice daily.
  • With Lasix and furosemide tablets, some people with severe edema take doses on 2 to 4 consecutive days each week.
Available strengths 3 strengths
252 FDA-listed product records ⓘ

Injection

By injection · Into a muscle · Into a vein · Under the skin
Brands Furoscix Lasix Onyu
How this form is used
What it may be used for
  • Furosemide injection treats edema from congestive heart failure, cirrhosis and kidney disease, and is add-on treatment for acute pulmonary edema.
  • Furoscix treats edema in adults with chronic heart failure or chronic kidney disease, and in children weighing 43 kg and above.
  • Lasix Onyu treats edema in adults with chronic heart failure.
Important instructions
  • Furosemide injection is for people who cannot take oral medicine or in emergencies, and is replaced with oral therapy as soon as practical.
  • Furosemide injection is given IV or IM; IV doses are given slowly.
  • Furoscix is not for chronic use and is replaced with oral diuretics as soon as practical.
  • Lasix Onyu is delivered by an infusor over about 5 hours, and you should limit activity during the infusion.
Available strengths 7 strengths
Show 1 more strength Show fewer strengths
154 FDA-listed product records ⓘ

Oral solution

By mouth
How this form is used
What it may be used for
  • Furosemide oral solution treats edema from congestive heart failure, cirrhosis and kidney disease, in adults and children.
  • Furosemide oral solution may be used in adults for high blood pressure, alone or with other medicines.
Available strengths 3 strengths
11 FDA-listed product records ⓘ

Furosemide on the U.S. market: products, makers and brands

How Furosemide appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

59 companies list 213 Furosemide product records with the FDA, mostly as tablet, injection, oral solution; the earliest marketing or approval year on record is 1966. Brand names on the directory include Lasix, Disal, Furoscix and 2 more; the rest are generics.

3
Dose forms ⓘ
59
Labelers (makers, repackagers, distributors)
4
Brand names
213
FDA-listed product records ⓘ
1966
Earliest FDA record ⓘ

FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

Also listed with the FDA, not a patient dose form: Powder (20) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

A-S Medication Solutions7%
Bryant Ranch Prepack7%
Hikma Pharmaceuticals USA Inc.6%
Aphena Pharma Solutions - Tennessee, LLC4%
Medical Purchasing Solutions, LLC4%
NuCare Pharmaceuticals,Inc.4%
Other makers68%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

How widely Furosemide is used (Medicaid data)

A general measure of how commonly Furosemide is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Furosemide is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

2,765,096
Medicaid prescriptions filled (Q1–Q4 2025)
$28.6M gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Furosemide prescribed? Of the 1,601 medications we measure, Furosemide ranks #84 by Medicaid prescriptions — more than 95% of them.

Where Furosemide ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5

Utilization by Furosemide product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

The 20 mg oral tablet is the most-dispensed Furosemide product — about 53% of these Medicaid prescriptions.

furosemide 20 MG Oral Tablet Most dispensed

1,461,653 Medicaid prescriptions (Q1–Q4 2025) 53% of Furosemide prescriptions shown $11.6M gross reimbursement (before rebates) ≈ $7.95 per prescription (gross)

Summed across the 13 of 289 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 310429

furosemide 40 MG Oral Tablet

1,136,281 Medicaid prescriptions (Q1–Q4 2025) 41% of Furosemide prescriptions shown $9.7M gross reimbursement (before rebates) ≈ $8.58 per prescription (gross)

Summed across the 14 of 250 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 313988

furosemide 80 MG Oral Tablet

88,495 Medicaid prescriptions (Q1–Q4 2025) 3% of Furosemide prescriptions shown $890,720 gross reimbursement (before rebates) ≈ $10 per prescription (gross)

Summed across the 11 of 77 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 197732

furosemide 10 MG/ML Oral Solution

43,061 Medicaid prescriptions (Q1–Q4 2025) 2% of Furosemide prescriptions shown $550,565 gross reimbursement (before rebates) ≈ $13 per prescription (gross)

Summed across the 2 of 22 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 197730

4 ML furosemide 10 MG/ML Injection

24,218 Medicaid prescriptions (Q1–Q4 2025) <1% of Furosemide prescriptions shown $958,901 gross reimbursement (before rebates) ≈ $40 per prescription (gross)

Summed across the 15 of 69 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1719291

2 ML furosemide 10 MG/ML Injection

8,631 Medicaid prescriptions (Q1–Q4 2025) <1% of Furosemide prescriptions shown $282,492 gross reimbursement (before rebates) ≈ $33 per prescription (gross)

Summed across the 12 of 62 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1719290

10 ML furosemide 10 MG/ML Injection

1,078 Medicaid prescriptions (Q1–Q4 2025) <1% of Furosemide prescriptions shown $52,848 gross reimbursement (before rebates) ≈ $49 per prescription (gross)

Summed across the 10 of 58 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1719286

furosemide 8 MG/ML Oral Solution

879 Medicaid prescriptions (Q1–Q4 2025) <1% of Furosemide prescriptions shown $10,845 gross reimbursement (before rebates) ≈ $12 per prescription (gross)

Summed across the 1 of 5 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 197731

10 ML furosemide 8 MG/ML Cartridge

800 Medicaid prescriptions (Q1–Q4 2025) <1% of Furosemide prescriptions shown $4.5M gross reimbursement (before rebates) ≈ $5,655 per prescription (gross)

Summed across the 1 of 1 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2621022

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Furosemide, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 79 of 833 listed Furosemide NDCs with Medicaid activity.

Compare Furosemide products

A representative set of FDA-listed product records for Furosemide — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Showing 200 of 213 products — FDA National Drug Code Directory. See every product, package size and price: browse all 213 Furosemide NDCs →

Furosemide side effects reported to the FDA (FAERS)

After a medicine reaches the market, patients, doctors and drugmakers can send the FDA reports of problems they think may be linked to it. Here’s what’s been reported for Furosemide — a signal of what to watch for, not proof the drug caused it.

The effects most often named in FDA reports that mention Furosemide are dyspnoea, fatigue, diarrhoea; about 81% of the reports were classed as serious. These are voluntary reports, so they show what people report, not how often it happens.

398,354
Reports mentioning it
81%
Reported as serious
12
Distinct effects shown
Most reported effects
Dyspnoea
29,961
Fatigue
21,054
Diarrhoea
20,618
Nausea
19,257
Acute Kidney Injury
19,011
Death
18,746
Fall
16,523
Pneumonia
16,480
Asthenia
15,485
Dizziness
15,210
Age groups
Elderly · 40,020Adult · 21,067Child · 576Neonate · 474Infant · 432Adolescent · 401

Source: openFDA, from the FDA Adverse Event Reporting System (FAERS). These are voluntary reports — they don’t prove the drug caused the effect, and counts reflect how often something was reported, not how often it actually happens. Reports also often name the very problem the medicine is taken for — a common reason to file one is that the drug didn’t help — so for a pain reliever you may see “pain” high on the list; that points to why the report was filed, not to the drug causing the symptom. This counts every report that lists Furosemide in any role, so the total runs higher than the FDA’s official dashboard, which counts only cases where the drug is the suspect. For the authoritative figures, see the FDA FAERS Public Dashboard. Always talk to your pharmacist or doctor.

Furosemide FDA approval history

How Furosemide went from FDA review to the pharmacy shelf — the key milestones in its regulatory journey.

Furosemide was first approved by the FDA in 1966 (Brand: LASIX · Validus Pharms); the first generic version was approved in 1985. It remains available in U.S. pharmacies today.

1966
Brand approved
Brand: LASIX · Validus Pharms
1985
First generic approved
Lower-cost ANDA competition begins
2026
Available today
Active in U.S. pharmacies

Source: Drugs@FDA.

Furosemide recall history

A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.

The FDA’s enforcement reports list 2 Furosemide recalls since July 2021. Both are still ongoing or began in the last six months. A recall names specific lots from one company, so check the lot number on your own bottle rather than assuming every product is affected; your pharmacist can check whether your supply came from an affected lot.

Ongoing Class II Mar 20, 2026 · Leading Pharma, LLC
CGMP Deviations; presence of N-nitroso-Furosemide (NNF) above the recommended intake limit.
  • Furosemide Tablets, USP, 80 mg, 100 Tablets bottles, Rx only, Manufactured by: Leading Pharma, LLC, Fairfield, NJ 07004, NDC 69315-118-01 Lots: Lots# H03125, H03225, H03325, Exp Date: 2027/08 FDA record D-0486-2026 →
Ongoing Class II Jan 10, 2026 · Graviti Pharmaceuticals Private Limited
Presence of Foreign Substance
  • Furosemide Tablets, USP 40 mg, 1,000 Tablets, Rx Only, Manufactured for: Rising Pharmaceuticals Inc., East Brunswick, NJ 08816, Manufactured by: Graviti Pharmaceuticals Pvt. Ltd. Telangana - 502307,… Lots: Lot# FUB125042G; Exp. 05/13/2027 FDA record D-0293-2026 →

Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Sep 24, 2026.

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Furosemide RxCUI 4603 7 dose forms · 20 strengths
  1. Dose form (SCDF) Auto-Injector RxCUI 2747764 In current FDA listings
    Clinical drug / strength (SCD) 1 ML furosemide 80 MG/ML RxCUI 2747765
  2. Dose form (SCDF) Injectable Solution RxCUI 95600 In current FDA listings
    Clinical drug / strength (SCD) 50 MG/ML RxCUI 204154
  3. Dose form (SCDF) Oral Solution RxCUI 372280 In current FDA listings
    Clinical drug / strength (SCD) 1 MG/ML RxCUI 251308 4 MG/ML RxCUI 104220 8 MG/ML RxCUI 197731 10 MG/ML RxCUI 197730
  4. Dose form (SCDF) Oral Tablet RxCUI 372281 In current FDA listings
    Clinical drug / strength (SCD) 12.5 MG RxCUI 630032 20 MG RxCUI 310429 40 MG RxCUI 313988 50 MG RxCUI 248657 80 MG RxCUI 197732 500 MG RxCUI 199610
  5. Dose form (SCDF) Prefilled Syringe RxCUI 727573 No current FDA listing
    Clinical drug / strength (SCD) 4 ML furosemide 10 MG/ML RxCUI 727575

Look up RxCUI 4603 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

Furosemide supply and shortage status

Whether Furosemide is in short supply in the U.S. right now, plus any shortage history the FDA has on record. A shortage usually reflects a manufacturing or demand issue — not a safety problem with the drug.

Furosemide is currently listed in shortage by the FDA (10 presentations on record).

⚠️Currently in shortage (FDA) — Furosemide

See the Furosemide shortage pages — affected NDCs, other makers, and what to do →

Current Furosemide, Injection, 10 mg/1 mL (NDC 63323-280-02)
Fresenius Kabi USA, LLC · Since 04/07/2020 · Updated 10/06/2026
Current Furosemide, Injection, 10 mg/1 mL (NDC 63323-280-10)
Fresenius Kabi USA, LLC · Since 04/07/2020 · Updated 10/06/2026
Current Furosemide, Injection, 10 mg/1 mL (NDC 63323-280-04)
Fresenius Kabi USA, LLC · Since 04/07/2020 · Updated 10/06/2026
Current Furosemide, Injection, 10 mg/1 mL (NDC 23155-473-44)
Avet Pharmaceuticals, Inc. · Since 04/07/2020 · Updated 10/05/2026
Reason: Other
Current Furosemide, Injection, 10 mg/1 mL (NDC 23155-473-42)
Avet Pharmaceuticals, Inc. · Since 04/07/2020 · Updated 10/05/2026
Current Furosemide, Injection, 10 mg/1 mL (NDC 23155-473-41)
Avet Pharmaceuticals, Inc. · Since 04/07/2020 · Updated 10/05/2026
Current Furosemide, Injection, 10 mg/1 mL (NDC 16729-500-08)
Accord Healthcare Inc. · Since 04/07/2020 · Updated 10/03/2026
Reason: Requirements related to complying with good manufacturing practices
Current Furosemide, Injection, 10 mg/1 mL (NDC 16729-502-43)
Accord Healthcare Inc. · Since 04/07/2020 · Updated 10/03/2026
Reason: Requirements related to complying with good manufacturing practices
Current Furosemide, Injection, 10 mg/1 mL (NDC 16729-501-43)
Accord Healthcare Inc. · Since 04/07/2020 · Updated 10/03/2026
Reason: Requirements related to complying with good manufacturing practices
Current Furosemide, Injection, 40 mg/4 mL (NDC 55150-323-25)
Eugia US LLC · Since 04/07/2020 · Updated 10/02/2026

Source: openFDA, from the FDA Drug Shortages database.

💵 What Furosemide costs pharmacies (NADAC benchmark)

The national average invoice price pharmacies pay for the drug itself, from CMS's NADAC survey (data as of Sep 30, 2026). This is a supply-cost benchmark — not a retail price and not what you'd pay at the counter.

FormStrengthPharmacy acquisition benchmark
Tablet · Oral 20 mg $0.026 per tablet NDC details & price history
Tablet · Oral 40 mg $0.029 per tablet NDC details & price history
Tablet · Oral 80 mg $0.050 per tablet NDC details & price history
Injection, Solution · Intramuscular, Intravenous 10 mg/mL $0.253–$0.490 per mL NDC details & price history
Injection, Solution · Intramuscular, Intravenous 40 mg/4 mL $0.253 per mL NDC details & price history
Injection, Solution · Intramuscular; Intravenous 10 mg/mL $0.253–$0.490 per mL NDC details & price history
Injection, Solution · Intramuscular; Intravenous 40 mg/4 mL $0.253 per mL NDC details & price history
Injection · Intramuscular, Intravenous 10 mg/mL $0.490 per mL NDC details & price history
Why show this? Your out-of-pocket cost depends on insurance, pharmacy markup, and discounts — but the acquisition benchmark tells you whether the medication itself is inexpensive or costly, which strengths cost more per dose, and whether a cash-price quote is in a reasonable range. Each row links to the NDC-level record with its full price history.

Source: CMS National Average Drug Acquisition Cost (NADAC), a survey of retail pharmacy invoice prices. Benchmarks shown are the range across package sizes of a representative product for each form and strength — other manufacturers' products may differ.

Furosemide brand names

Furosemide is sold under 5 brand names in the FDA directory — Lasix, Disal, Furoscix, Salix - substance and others. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.

Lasix Disal Furoscix Salix - substance Lasix Onyu

Who makes Furosemide: manufacturers and labelers

59 companies list Furosemide products with the FDA. By number of product records, the largest are A-S Medication Solutions, Bryant Ranch Prepack, Hikma Pharmaceuticals USA Inc.. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.

A-S Medication Solutions 15 Bryant Ranch Prepack 14 Hikma Pharmaceuticals USA Inc. 13 Aphena Pharma Solutions - Tennessee, LLC 9 Medical Purchasing Solutions, LLC 9 NuCare Pharmaceuticals,Inc. 9 Remedyrepack Inc. 8 Cardinal Health 107, LLC 7 PD-Rx Pharmaceuticals, Inc. 7 Baxter Healthcare Corporation 6 HF Acquisition Co LLC, DBA HealthFirst 6 Northwind Health Company, LLC 5 Coupler LLC 4 Proficient Rx LP 4 Accord Healthcare, Inc. 3 Aurobindo Pharma Limited 3 AvKARE 3 Camber Pharmaceuticals, Inc. 3 Devatis Inc. 3 Eugia US LLC 3 Gland Pharma Limited 3 Granulation Technology, Inc. 3 Henry Schein, Inc. 3 Ipca Laboratories Limited 3

…and 35 more on the FDA NDC directory.

Furosemide drug class (RxNorm)

Furosemide belongs to the Loop Diuretic class.

Pharmacologic class Loop Diuretic
Drug family (ATC) Sulfonamides, plain

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

Sources for this Furosemide page

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Nov 3, 2025
🏭
Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Furosemide.
📈
Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
🚨
Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Furosemide after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
108
Finished products in the current FDA directory
213
Companies listing them (makers, repackagers, distributors)
59
FDA labeler codes behind them ⓘ
63
Linked representative label ⓘ
West-Ward Pharmaceuticals Corp.
Linked label effective
Nov 3, 2025
Composite sections available
18
Linked SPL Set ID
9e493331-dddd-496e-abf8-61747fb67aba
Linked SPL Document ID
bc62ddda-7639-4090-99f0-7dd4d13518f3
Open the linked representative label on DailyMed ↗

How this page is built

HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. West-Ward Pharmaceuticals Corp. is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →