Mirtazapine

Mirtazapine is used to treat depression. Mirtazapine is in a class of medications called antidepressants. It works by increasing certain types of activity in the brain to maintain mental balance.

Mirtazapine comes as a tablet and as a disintegrating tablet to take by mouth. It usually is taken once a day at bedtime. It may be taken with or without food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take mirtazapine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

To take a mirtazapine disintegrating tablet, open the blister pack with dry hands and place the tablet on your tongue. The tablet will disintegrate on the tongue and can be swallowed with saliva. No water is needed to swallow disintegrating tablets. Once the tablet is removed from the blister pack, it cannot be stored. Do not split mirtazapine disintegrating tablets.

It may take several weeks or longer for you to feel the full benefit of mirtazapine. Continue to take mirtazapine even if you feel well. Do not stop taking mirtazapine without talking to your doctor. Your doctor probably will decrease your dose gradually.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking mirtazapine,

• tell your doctor and pharmacist if you are allergic to mirtazapine, any other medications, or any of the ingredients in mirtazapine tablets or disintegrating tablets. Ask your doctor or pharmacist for a list of the ingredients.

• tell your doctor if you are taking a monoamine oxidase (MAO) inhibitor such as isocarboxazid (Marplan), linezolid (Zyvox), methylene blue, phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate) or if you have stopped taking an MAO inhibitor within the past 14 days. Your doctor will probably tell you not to take mirtazapine. If you stop taking mirtazapine, you should wait at least 14 days before you start to take an MAO inhibitor.

• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); antidepressants such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin, imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); certain antifungals such as ketoconazole (Nizoral); buspirone; carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, other); cimetidine (Tagamet); diazepam (Valium); erythromycin (E.E.S., E-mycin, Erythrocin); fentanyl (Abstral, Actiq, Fentora, Onsolis, others); lithium (Eskalith, Lithobid); medications for migraine headaches such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), and zolmitriptan (Zomig); certain medications to treat HIV; medications for anxiety and seizures; nefazodone; phenytoin (Dilantin); rifampin (Rimactane, Rifadin, in Rifater, in Rifamate); sedatives; selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil, Pexeva), and sertraline (Zoloft); selective serotonin and norepinephrine reuptake inhibitors (SNRIs) such as desvenlafaxine (Pristiq), duloxetine (Cymbalta), and venlafaxine (Effexor); sleeping pills; tramadol (Ultram); and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

• tell your doctor what herbal products you are taking, especially St. John's wort and tryptophan.

• tell your doctor if you have or have ever had a heart attack, low blood pressure, heart, kidney, or liver disease, or high cholesterol.

• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking mirtazapine, call your doctor.

• if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking mirtazapine.

• you should know that this medication may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.

• remember that alcohol can add to the drowsiness caused by this medication.

• if you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent damage to your brain that can cause severe intellectual disability), you should know that the orally disintegrating tablets contain aspartame that forms phenylalanine.

• you should know that mirtazapine may cause angle-closure glaucoma (a condition where the fluid is suddenly blocked and unable to flow out of the eye causing a quick, severe increase in eye pressure which may lead to a loss of vision). Talk to your doctor about having an eye examination before you start taking this medication. If you have nausea, eye pain, changes in vision, such as seeing colored rings around lights, and swelling or redness in or around the eye, call your doctor or get emergency medical treatment right away.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

• Mirtazapine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • drowsiness

  • dizziness

  • anxiousness

  • confusion

  • increased weight and appetite

  • dry mouth

  • constipation

  • nausea

  • vomiting

• Some side effects can be serious. If you experience any of the following symptoms or those listed in the IMPORTANT WARNING or SPECIAL PRECAUTIONS section, call your doctor immediately or get emergency medical treatment:

  • flu-like symptoms, fever, chills, sore throat, mouth sores, or other signs of infection

  • chest pain

  • fast heartbeat

  • seizures

• Mirtazapine may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.

• If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to mirtazapine.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug	Interaction
Moxifloxacin	Moxifloxacin The metabolism of Mirtazapine can be decreased when combined with Moxifloxacin.
Insulin Glargine (rDNA origin) Injection	Insulin Glargine (rDNA origin) Injection The metabolism of Mirtazapine can be increased when combined with Insulin glargine.
Leflunomide	Leflunomide The serum concentration of Mirtazapine can be decreased when it is combined with Leflunomide.
Delavirdine	Delavirdine The metabolism of Mirtazapine can be decreased when combined with Delavirdine.
Nevirapine	Nevirapine The metabolism of Mirtazapine can be decreased when combined with Nevirapine.
Atorvastatin	Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Mirtazapine.
Dolasetron	Dolasetron Dolasetron may increase the serotonergic activities of Mirtazapine.
Aminophylline	Aminophylline The metabolism of Aminophylline can be decreased when combined with Mirtazapine.
Anagrelide	Anagrelide The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Anagrelide.
Candesartan	Candesartan Mirtazapine may decrease the antihypertensive activities of Candesartan.
Cilostazol	Cilostazol The metabolism of Cilostazol can be decreased when combined with Mirtazapine.
Clopidogrel	Clopidogrel The metabolism of Clopidogrel can be decreased when combined with Mirtazapine.
Diphenoxylate	Diphenoxylate Diphenoxylate may increase the serotonergic activities of Mirtazapine.
Erythromycin and Sulfisoxazole	Erythromycin and Sulfisoxazole The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives)	Estrogen and Progestin (Oral Contraceptives) The metabolism of Mirtazapine can be decreased when combined with Conjugated estrogens.
Fenofibrate	Fenofibrate The metabolism of Fenofibrate can be decreased when combined with Mirtazapine.
Guanfacine	Guanfacine Guanfacine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Methylergonovine	Methylergonovine The risk or severity of hypertension can be increased when Methylergometrine is combined with Mirtazapine.
Naratriptan	Naratriptan Naratriptan may increase the serotonergic activities of Mirtazapine.
Olsalazine	Olsalazine The risk or severity of hypertension can be increased when Mirtazapine is combined with Olsalazine.
Paregoric	Paregoric Morphine may increase the serotonergic activities of Mirtazapine.
Penbutolol	Penbutolol The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Acebutolol.
Pentazocine	Pentazocine Pentazocine may increase the serotonergic activities of Mirtazapine.
Ranitidine	Ranitidine The metabolism of Ranitidine can be decreased when combined with Mirtazapine.
Reserpine	Reserpine Reserpine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Rizatriptan	Rizatriptan Rizatriptan may increase the serotonergic activities of Mirtazapine.
Sumatriptan	Sumatriptan Sumatriptan may increase the serotonergic activities of Mirtazapine.
Tacrolimus	Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Mirtazapine.
Tizanidine	Tizanidine Tizanidine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Zolmitriptan	Zolmitriptan Zolmitriptan may increase the serotonergic activities of Mirtazapine.
Famotidine Injection	Famotidine Injection The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Famotidine.
Fluconazole Injection	Fluconazole Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Mirtazapine.
Foscarnet Injection	Foscarnet Injection The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Foscarnet.
Hydromorphone Injection	Hydromorphone Injection Hydromorphone may increase the serotonergic activities of Mirtazapine.
Interferon Beta-1b Injection	Interferon Beta-1b Injection The metabolism of Mirtazapine can be decreased when combined with Interferon beta-1b.
Interferon Gamma-1b Injection	Interferon Gamma-1b Injection The metabolism of Mirtazapine can be decreased when combined with Interferon gamma-1b.
Levofloxacin Injection	Levofloxacin Injection The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Levofloxacin.
Meperidine Injection	Meperidine Injection Meperidine may increase the serotonergic activities of Mirtazapine.
Metoclopramide Injection	Metoclopramide Injection Metoclopramide may increase the serotonergic activities of Mirtazapine.
Metronidazole Injection	Metronidazole Injection The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Metronidazole.
Morphine Injection	Morphine Injection Morphine may increase the serotonergic activities of Mirtazapine.
Altretamine	Altretamine Amphetamine may increase the serotonergic activities of Mirtazapine.
Cyclosporine	Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Mirtazapine.
Ondansetron	Ondansetron Ondansetron may increase the serotonergic activities of Mirtazapine.
Granisetron	Granisetron Granisetron may increase the serotonergic activities of Mirtazapine.
Torsemide	Torsemide Mirtazapine may decrease the antihypertensive activities of Torasemide.
Olanzapine	Olanzapine Olanzapine may increase the serotonergic activities of Mirtazapine.
Alosetron	Alosetron Alosetron may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Dofetilide	Dofetilide The metabolism of Dofetilide can be decreased when combined with Mirtazapine.
Entacapone	Entacapone Entacapone may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Eprosartan	Eprosartan Mirtazapine may decrease the antihypertensive activities of Eprosartan.
Hydroxychloroquine	Hydroxychloroquine The metabolism of Mirtazapine can be decreased when combined with Hydroxychloroquine.
Meloxicam	Meloxicam The risk or severity of hypertension can be increased when Mirtazapine is combined with Meloxicam.
Oxcarbazepine	Oxcarbazepine Oxcarbazepine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Telmisartan	Telmisartan Mirtazapine may decrease the antihypertensive activities of Telmisartan.
Zaleplon	Zaleplon Zaleplon may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Anakinra	Anakinra The metabolism of Mirtazapine can be increased when combined with Anakinra.
Desloratadine	Desloratadine Desloratadine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Linezolid	Linezolid Linezolid may increase the serotonergic activities of Mirtazapine.
Trimipramine	Trimipramine Trimipramine may increase the serotonergic activities of Mirtazapine.
Etanercept Injection	Etanercept Injection The metabolism of Mirtazapine can be increased when combined with Etanercept.
Glycopyrrolate	Glycopyrrolate Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium.
Modafinil	Modafinil The metabolism of Mirtazapine can be increased when combined with Armodafinil.
Perindopril	Perindopril Mirtazapine may decrease the antihypertensive activities of Perindopril.
Tenofovir	Tenofovir The metabolism of Tenofovir can be decreased when combined with Mirtazapine.
Choline Magnesium Trisalicylate	Choline Magnesium Trisalicylate The risk or severity of hypertension can be increased when Mirtazapine is combined with Choline magnesium trisalicylate.
Sirolimus	Sirolimus The metabolism of Sirolimus can be decreased when combined with Mirtazapine.
Dutasteride	Dutasteride The risk or severity of hypertension can be increased when Mirtazapine is combined with Dutasteride.
Epinephrine Injection	Epinephrine Injection Mirtazapine may decrease the antihypertensive activities of Epinephrine.
Eplerenone	Eplerenone Mirtazapine may decrease the antihypertensive activities of Eplerenone.
Escitalopram	Escitalopram Escitalopram may increase the serotonergic activities of Mirtazapine.
Olmesartan	Olmesartan Mirtazapine may decrease the antihypertensive activities of Olmesartan.
Zonisamide	Zonisamide Zonisamide may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Adalimumab Injection	Adalimumab Injection The metabolism of Mirtazapine can be increased when combined with Adalimumab.
Aripiprazole	Aripiprazole Aripiprazole may increase the serotonergic activities of Mirtazapine.
Atomoxetine	Atomoxetine Atomoxetine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Dexmethylphenidate	Dexmethylphenidate Dexmethylphenidate may increase the serotonergic activities of Mirtazapine.
Atazanavir	Atazanavir The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Atazanavir.
Almotriptan	Almotriptan Almotriptan may increase the serotonergic activities of Mirtazapine.
Eletriptan	Eletriptan Eletriptan may increase the serotonergic activities of Mirtazapine.
Mefloquine	Mefloquine The risk or severity of QTc prolongation can be increased when Mefloquine is combined with Mirtazapine.
Rosuvastatin	Rosuvastatin The metabolism of Rosuvastatin can be decreased when combined with Mirtazapine.
Vardenafil	Vardenafil The metabolism of Vardenafil can be decreased when combined with Mirtazapine.
Alfuzosin	Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Mirtazapine.
Interferon Beta-1a Subcutaneous Injection	Interferon Beta-1a Subcutaneous Injection The metabolism of Mirtazapine can be decreased when combined with Interferon beta-1a.
Tegaserod	Tegaserod Tegaserod may increase the serotonergic activities of Mirtazapine.
Tadalafil	Tadalafil Mirtazapine may decrease the antihypertensive activities of Tadalafil.
Frovatriptan	Frovatriptan Frovatriptan may increase the serotonergic activities of Mirtazapine.
Gemifloxacin	Gemifloxacin The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Gemifloxacin.
Progesterone	Progesterone The metabolism of Progesterone can be decreased when combined with Mirtazapine.
Apomorphine Injection	Apomorphine Injection Apomorphine may increase the serotonergic activities of Mirtazapine.
Infliximab Injection	Infliximab Injection The metabolism of Mirtazapine can be increased when combined with Infliximab.
Protriptyline	Protriptyline Protriptyline may increase the serotonergic activities of Mirtazapine.
Duloxetine	Duloxetine Duloxetine may increase the serotonergic activities of Mirtazapine.
Norethindrone	Norethindrone The metabolism of Norethisterone can be decreased when combined with Mirtazapine.
Trospium	Trospium Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Trospium.
Bosentan	Bosentan Mirtazapine may decrease the antihypertensive activities of Bosentan.
Cinacalcet	Cinacalcet The metabolism of Mirtazapine can be decreased when combined with Cinacalcet.
Erlotinib	Erlotinib The metabolism of Erlotinib can be decreased when combined with Mirtazapine.
Eszopiclone	Eszopiclone The risk or severity of CNS depression can be increased when Mirtazapine is combined with Eszopiclone.
Solifenacin	Solifenacin Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Voriconazole	Voriconazole The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Voriconazole.
Dextroamphetamine	Dextroamphetamine Amphetamine may increase the serotonergic activities of Mirtazapine.
Entecavir	Entecavir The metabolism of Entecavir can be decreased when combined with Mirtazapine.
Peginterferon Alfa-2a Injection	Peginterferon Alfa-2a Injection The metabolism of Mirtazapine can be decreased when combined with Peginterferon alfa-2a.
Peginterferon Alfa-2b (PEG-Intron)	Peginterferon Alfa-2b (PEG-Intron) The serum concentration of Mirtazapine can be increased when it is combined with Peginterferon alfa-2b.
Sodium Oxybate	Sodium Oxybate Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Ibandronate	Ibandronate The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Ibandronate.
Isocarboxazid	Isocarboxazid Isocarboxazid may increase the serotonergic activities of Mirtazapine.
Ramelteon	Ramelteon Ramelteon may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Darifenacin	Darifenacin The metabolism of Darifenacin can be decreased when combined with Mirtazapine.
Fentanyl	Fentanyl The metabolism of Mirtazapine can be decreased when combined with Fentanyl.
Pregabalin	Pregabalin The therapeutic efficacy of Mirtazapine can be increased when used in combination with Pregabalin.
Deferasirox	Deferasirox The serum concentration of Mirtazapine can be increased when it is combined with Deferasirox.
Phenylephrine	Phenylephrine The metabolism of Mirtazapine can be increased when combined with Phenylephrine.
Tipranavir	Tipranavir The metabolism of Tipranavir can be decreased when combined with Mirtazapine.
Felbamate	Felbamate Felbamate may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Ranolazine	Ranolazine The serum concentration of Mirtazapine can be increased when it is combined with Ranolazine.
Abatacept Injection	Abatacept Injection The metabolism of Mirtazapine can be increased when combined with Abatacept.
Rasagiline	Rasagiline Rasagiline may increase the serotonergic activities of Mirtazapine.
Imatinib	Imatinib The metabolism of Mirtazapine can be decreased when combined with Imatinib.
Gefitinib	Gefitinib The metabolism of Mirtazapine can be decreased when combined with Gefitinib.
Albuterol	Albuterol The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Salbutamol.
Paliperidone	Paliperidone Paliperidone may increase the serotonergic activities of Mirtazapine.
Bortezomib	Bortezomib The metabolism of Mirtazapine can be decreased when combined with Bortezomib.
Insulin Glulisine (rDNA origin) Injection	Insulin Glulisine (rDNA origin) Injection The metabolism of Mirtazapine can be increased when combined with Insulin glulisine.
Oxaliplatin Injection	Oxaliplatin Injection The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Oxaliplatin.
Posaconazole	Posaconazole The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Posaconazole.
Primaquine	Primaquine The metabolism of Primaquine can be decreased when combined with Mirtazapine.
Aliskiren	Aliskiren Mirtazapine may decrease the antihypertensive activities of Aliskiren.
Pemetrexed Injection	Pemetrexed Injection The metabolism of Pemetrexed can be decreased when combined with Mirtazapine.
Dimenhydrinate	Dimenhydrinate Dimenhydrinate may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Lisdexamfetamine	Lisdexamfetamine Lisdexamfetamine may increase the serotonergic activities of Mirtazapine.
Nabilone	Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Retapamulin	Retapamulin The metabolism of Retapamulin can be decreased when combined with Mirtazapine.
Vorinostat	Vorinostat The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Vorinostat.
Sorafenib	Sorafenib The metabolism of Sorafenib can be decreased when combined with Mirtazapine.
Sunitinib	Sunitinib The risk or severity of QTc prolongation and torsade de pointes can be increased when Sunitinib is combined with Mirtazapine.
Dronabinol	Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Lapatinib	Lapatinib The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Lapatinib.
Levocetirizine	Levocetirizine Levocetirizine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Dasatinib	Dasatinib The metabolism of Dasatinib can be decreased when combined with Mirtazapine.
Mexiletine	Mexiletine The metabolism of Mirtazapine can be decreased when combined with Mexiletine.
Armodafinil	Armodafinil The metabolism of Mirtazapine can be increased when combined with Armodafinil.
Temsirolimus	Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Mirtazapine.
Nilotinib	Nilotinib The metabolism of Nilotinib can be decreased when combined with Mirtazapine.
Toremifene	Toremifene The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Toremifene.
Desmopressin	Desmopressin The risk or severity of hypertension can be increased when Desmopressin is combined with Mirtazapine.
OnabotulinumtoxinA Injection	OnabotulinumtoxinA Injection Botulinum toxin type A may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
RimabotulinumtoxinB Injection	RimabotulinumtoxinB Injection Botulinum Toxin Type B may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Arsenic Trioxide Injection	Arsenic Trioxide Injection The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Arsenic trioxide.
Desvenlafaxine	Desvenlafaxine Desvenlafaxine may increase the serotonergic activities of Mirtazapine.
Cevimeline	Cevimeline The metabolism of Mirtazapine can be decreased when combined with Cevimeline.
Nebivolol	Nebivolol Mirtazapine may decrease the antihypertensive activities of Nebivolol.
Bendamustine Injection	Bendamustine Injection The metabolism of Bendamustine can be decreased when combined with Mirtazapine.
Flecainide	Flecainide The metabolism of Flecainide can be decreased when combined with Mirtazapine.
Certolizumab Injection	Certolizumab Injection The metabolism of Mirtazapine can be increased when combined with Certolizumab pegol.
Ixabepilone Injection	Ixabepilone Injection The metabolism of Ixabepilone can be decreased when combined with Mirtazapine.
Irinotecan Injection	Irinotecan Injection The metabolism of Irinotecan can be decreased when combined with Mirtazapine.
Praziquantel	Praziquantel The metabolism of Praziquantel can be decreased when combined with Mirtazapine.
Rufinamide	Rufinamide Rufinamide may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Midazolam	Midazolam The serum concentration of Midazolam can be increased when it is combined with Mirtazapine.
Naltrexone Injection	Naltrexone Injection Naltrexone may increase the serotonergic activities of Mirtazapine.
Eltrombopag	Eltrombopag The metabolism of Eltrombopag can be decreased when combined with Mirtazapine.
Milnacipran	Milnacipran Milnacipran may increase the serotonergic activities of Mirtazapine.
Fesoterodine	Fesoterodine Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Fesoterodine.
Degarelix Injection	Degarelix Injection The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Degarelix.
Betaxolol	Betaxolol The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Betaxolol.
Iloperidone	Iloperidone Iloperidone may increase the serotonergic activities of Mirtazapine.
Lacosamide	Lacosamide Lacosamide may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Everolimus	Everolimus The metabolism of Mirtazapine can be decreased when combined with Everolimus.
Tolvaptan (low blood sodium)	Tolvaptan (low blood sodium) The metabolism of Tolvaptan can be decreased when combined with Mirtazapine.
Dronedarone	Dronedarone The metabolism of Dronedarone can be decreased when combined with Mirtazapine.
AbobotulinumtoxinA Injection	AbobotulinumtoxinA Injection Botulinum toxin type A may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Palonosetron Injection	Palonosetron Injection Palonosetron may increase the serotonergic activities of Mirtazapine.
Telavancin Injection	Telavancin Injection The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Telavancin.
Romidepsin Injection	Romidepsin Injection The metabolism of Romidepsin can be decreased when combined with Mirtazapine.
Tapentadol	Tapentadol Tapentadol may increase the serotonergic activities of Mirtazapine.
Golimumab Injection	Golimumab Injection The metabolism of Mirtazapine can be increased when combined with Golimumab.
Pazopanib	Pazopanib The metabolism of Pazopanib can be decreased when combined with Mirtazapine.
Asenapine	Asenapine Asenapine may increase the serotonergic activities of Mirtazapine.
Vigabatrin	Vigabatrin Vigabatrin may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Albendazole	Albendazole The metabolism of Albendazole can be decreased when combined with Mirtazapine.
Oxymorphone	Oxymorphone Oxymorphone may increase the serotonergic activities of Mirtazapine.
Tocilizumab Injection	Tocilizumab Injection The metabolism of Mirtazapine can be increased when combined with Tocilizumab.
Eribulin Injection	Eribulin Injection The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Eribulin.
IncobotulinumtoxinA Injection	IncobotulinumtoxinA Injection Botulinum toxin type A may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Cabazitaxel Injection	Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Mirtazapine.
Lurasidone	Lurasidone Lurasidone may increase the serotonergic activities of Mirtazapine.
Acetaminophen Injection	Acetaminophen Injection The metabolism of Mirtazapine can be decreased when combined with Acetaminophen.
Vilazodone	Vilazodone Vilazodone may increase the serotonergic activities of Mirtazapine.
Terbutaline Injection	Terbutaline Injection The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Terbutaline.
Busulfan Injection	Busulfan Injection The metabolism of Busulfan can be decreased when combined with Mirtazapine.
Roflumilast	Roflumilast The metabolism of Roflumilast can be decreased when combined with Mirtazapine.
Linagliptin	Linagliptin The metabolism of Linagliptin can be decreased when combined with Mirtazapine.
Rilpivirine	Rilpivirine The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Rilpivirine.
Cyclophosphamide Injection	Cyclophosphamide Injection The metabolism of Cyclophosphamide can be decreased when combined with Mirtazapine.
Abiraterone	Abiraterone The serum concentration of Mirtazapine can be increased when it is combined with Abiraterone.
Triptorelin Injection	Triptorelin Injection The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Triptorelin.
Brentuximab Vedotin Injection	Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be decreased when combined with Mirtazapine.
Ruxolitinib	Ruxolitinib The metabolism of Ruxolitinib can be decreased when combined with Mirtazapine.
Vandetanib	Vandetanib The metabolism of Vandetanib can be decreased when combined with Mirtazapine.
Clobazam	Clobazam Clobazam may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Vemurafenib	Vemurafenib The serum concentration of Mirtazapine can be increased when it is combined with Vemurafenib.
Axitinib	Axitinib The metabolism of Axitinib can be decreased when combined with Mirtazapine.
Crizotinib	Crizotinib The metabolism of Crizotinib can be decreased when combined with Mirtazapine.
Cabergoline	Cabergoline Cabergoline may increase the serotonergic activities of Mirtazapine.
Ambrisentan	Ambrisentan Mirtazapine may decrease the antihypertensive activities of Ambrisentan.
Ezogabine	Ezogabine Tiagabine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Mirabegron	Mirabegron The metabolism of Mirabegron can be decreased when combined with Mirtazapine.
Regorafenib	Regorafenib The metabolism of Regorafenib can be decreased when combined with Mirtazapine.
Bosutinib	Bosutinib The metabolism of Bosutinib can be decreased when combined with Mirtazapine.
Teriflunomide	Teriflunomide The serum concentration of Mirtazapine can be decreased when it is combined with Teriflunomide.
Bedaquiline	Bedaquiline The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Bedaquiline.
Tofacitinib	Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Mirtazapine.
Alogliptin	Alogliptin The metabolism of Alogliptin can be decreased when combined with Mirtazapine.
Ponatinib	Ponatinib The metabolism of Ponatinib can be decreased when combined with Mirtazapine.
Pomalidomide	Pomalidomide Pomalidomide may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Ado-trastuzumab Emtansine Injection	Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be decreased when combined with Mirtazapine.
Dabrafenib	Dabrafenib The metabolism of Dabrafenib can be decreased when combined with Mirtazapine.
Ospemifene	Ospemifene The metabolism of Mirtazapine can be decreased when combined with Ospemifene.
Levomilnacipran	Levomilnacipran Levomilnacipran may increase the serotonergic activities of Mirtazapine.
Vortioxetine	Vortioxetine Vortioxetine may increase the serotonergic activities of Mirtazapine.
Perampanel	Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Ibrutinib	Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Mirtazapine.
Lomitapide	Lomitapide The metabolism of Lomitapide can be decreased when combined with Mirtazapine.
Ketorolac Injection	Ketorolac Injection The risk or severity of hypertension can be increased when Mirtazapine is combined with Ketorolac.
Simeprevir	Simeprevir The metabolism of Mirtazapine can be decreased when combined with Simeprevir.
Dapagliflozin	Dapagliflozin The metabolism of Mirtazapine can be decreased when combined with Dapagliflozin.
Apremilast	Apremilast The metabolism of Mirtazapine can be increased when combined with Apremilast.
Droxidopa	Droxidopa Mirtazapine may decrease the antihypertensive activities of Droxidopa.
Ceritinib	Ceritinib The metabolism of Ceritinib can be decreased when combined with Mirtazapine.
Siltuximab Injection	Siltuximab Injection The metabolism of Mirtazapine can be increased when combined with Siltuximab.
Eslicarbazepine	Eslicarbazepine Eslicarbazepine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Belinostat Injection	Belinostat Injection The metabolism of Mirtazapine can be increased when combined with Belinostat.
Idelalisib	Idelalisib The metabolism of Idelalisib can be decreased when combined with Mirtazapine.
Oritavancin Injection	Oritavancin Injection The metabolism of Mirtazapine can be decreased when combined with Oritavancin.
Vorapaxar	Vorapaxar The metabolism of Vorapaxar can be decreased when combined with Mirtazapine.
Hydrocodone	Hydrocodone Hydrocodone may increase the serotonergic activities of Mirtazapine.
Suvorexant	Suvorexant Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Peginterferon Beta-1a Injection	Peginterferon Beta-1a Injection The metabolism of Mirtazapine can be decreased when combined with Peginterferon beta-1a.
Olaparib	Olaparib The metabolism of Olaparib can be decreased when combined with Mirtazapine.
Methamphetamine	Methamphetamine Metamfetamine may increase the serotonergic activities of Mirtazapine.
Tasimelteon	Tasimelteon Tasimelteon may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Riociguat	Riociguat Mirtazapine may decrease the antihypertensive activities of Riociguat.
Pirfenidone	Pirfenidone The metabolism of Pirfenidone can be decreased when combined with Mirtazapine.
Nintedanib	Nintedanib The metabolism of Nintedanib can be decreased when combined with Mirtazapine.
Secukinumab Injection	Secukinumab Injection The metabolism of Mirtazapine can be increased when combined with Secukinumab.
Risperidone Injection	Risperidone Injection Risperidone may increase the serotonergic activities of Mirtazapine.
Palbociclib	Palbociclib The metabolism of Palbociclib can be decreased when combined with Mirtazapine.
Insulin Human Inhalation	Insulin Human Inhalation The metabolism of Mirtazapine can be increased when combined with Insulin human.
Lenvatinib	Lenvatinib The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Lenvatinib.
Naloxegol	Naloxegol The metabolism of Mirtazapine can be decreased when combined with Naloxegol.
Panobinostat	Panobinostat The metabolism of Mirtazapine can be decreased when combined with Panobinostat.
Haloperidol Injection	Haloperidol Injection The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Haloperidol.
Ivabradine	Ivabradine The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Ivabradine.
Macitentan	Macitentan Mirtazapine may decrease the antihypertensive activities of Macitentan.
Sonidegib	Sonidegib The metabolism of Sonidegib can be decreased when combined with Mirtazapine.
Flibanserin	Flibanserin Flibanserin may increase the serotonergic activities of Mirtazapine.
Rolapitant	Rolapitant The metabolism of Mirtazapine can be decreased when combined with Rolapitant.
Brexpiprazole	Brexpiprazole Brexpiprazole may increase the serotonergic activities of Mirtazapine.
Ziprasidone Injection	Ziprasidone Injection Ziprasidone may increase the serotonergic activities of Mirtazapine.
Cariprazine	Cariprazine Cariprazine may increase the serotonergic activities of Mirtazapine.
Eluxadoline	Eluxadoline Eluxadoline may increase the serotonergic activities of Mirtazapine.
Insulin Degludec (rDNA Origin) Injection	Insulin Degludec (rDNA Origin) Injection The metabolism of Mirtazapine can be increased when combined with Insulin degludec.
Cobimetinib	Cobimetinib The metabolism of Cobimetinib can be decreased when combined with Mirtazapine.
Trabectedin Injection	Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Mirtazapine.
Osimertinib	Osimertinib The serum concentration of Mirtazapine can be decreased when it is combined with Osimertinib.
Alectinib	Alectinib The metabolism of Alectinib can be decreased when combined with Mirtazapine.
Ixazomib	Ixazomib The metabolism of Ixazomib can be decreased when combined with Mirtazapine.
Brivaracetam Injection	Brivaracetam Injection Brivaracetam may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Venetoclax	Venetoclax The metabolism of Venetoclax can be decreased when combined with Mirtazapine.
Cobicistat	Cobicistat The metabolism of Mirtazapine can be decreased when combined with Cobicistat.
Midodrine	Midodrine The risk or severity of hypertension can be increased when Midodrine is combined with Mirtazapine.
Selexipag	Selexipag Mirtazapine may decrease the antihypertensive activities of Selexipag.
Pimavanserin	Pimavanserin Pimavanserin may increase the serotonergic activities of Mirtazapine.
Obeticholic Acid	Obeticholic Acid The metabolism of Mirtazapine can be decreased when combined with Obeticholic acid.
Diphenhydramine Injection	Diphenhydramine Injection Diphenhydramine may increase the serotonergic activities of Mirtazapine.
Furosemide Injection	Furosemide Injection Mirtazapine may decrease the antihypertensive activities of Furosemide.
Rucaparib	Rucaparib The metabolism of Rucaparib can be decreased when combined with Mirtazapine.
Ribociclib	Ribociclib The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Ribociclib.
Brigatinib	Brigatinib The metabolism of Brigatinib can be decreased when combined with Mirtazapine.
Doxepin (Insomnia)	Doxepin (Insomnia) Doxepin may increase the serotonergic activities of Mirtazapine.
Deutetrabenazine	Deutetrabenazine The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Deutetrabenazine.
Valbenazine	Valbenazine The metabolism of Valbenazine can be decreased when combined with Mirtazapine.
Safinamide	Safinamide Safinamide may increase the serotonergic activities of Mirtazapine.
Midostaurin	Midostaurin The metabolism of Mirtazapine can be decreased when combined with Midostaurin.
Neratinib	Neratinib The metabolism of Neratinib can be decreased when combined with Mirtazapine.
Enasidenib	Enasidenib The metabolism of Mirtazapine can be decreased when combined with Enasidenib.
Aprepitant/Fosaprepitant Injection	Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be decreased when combined with Mirtazapine.
Copanlisib Injection	Copanlisib Injection The metabolism of Copanlisib can be decreased when combined with Mirtazapine.
Delafloxacin	Delafloxacin The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Delafloxacin.
Abemaciclib	Abemaciclib The metabolism of Abemaciclib can be decreased when combined with Mirtazapine.
Acalabrutinib	Acalabrutinib The metabolism of Acalabrutinib can be decreased when combined with Mirtazapine.
Letermovir	Letermovir The metabolism of Letermovir can be decreased when combined with Mirtazapine.
Tetrabenazine	Tetrabenazine The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Tetrabenazine.
Buprenorphine Injection	Buprenorphine Injection Buprenorphine may increase the serotonergic activities of Mirtazapine.
Baricitinib	Baricitinib The metabolism of Baricitinib can be decreased when combined with Mirtazapine.
Lofexidine	Lofexidine Lofexidine may increase the serotonergic activities of Mirtazapine.
Eliglustat	Eliglustat The metabolism of Eliglustat can be decreased when combined with Mirtazapine.
Encorafenib	Encorafenib The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Encorafenib.
Binimetinib	Binimetinib The metabolism of Binimetinib can be decreased when combined with Mirtazapine.
Ivosidenib	Ivosidenib The metabolism of Ivosidenib can be decreased when combined with Mirtazapine.
Elagolix	Elagolix The metabolism of Elagolix can be decreased when combined with Mirtazapine.
Tafenoquine	Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Mirtazapine.
Cannabidiol	Cannabidiol Cannabidiol may increase the serotonergic activities of Mirtazapine.
Dacomitinib	Dacomitinib The metabolism of Mirtazapine can be decreased when combined with Dacomitinib.
Duvelisib	Duvelisib The metabolism of Duvelisib can be decreased when combined with Mirtazapine.
Stiripentol	Stiripentol Stiripentol may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Gilteritinib	Gilteritinib The therapeutic efficacy of Mirtazapine can be decreased when used in combination with Gilteritinib.
Glasdegib	Glasdegib The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Glasdegib.
Paclitaxel (with albumin) Injection	Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Mirtazapine.
Rifamycin	Rifamycin The metabolism of Mirtazapine can be decreased when combined with Rifamycin.
Prucalopride	Prucalopride The metabolism of Prucalopride can be decreased when combined with Mirtazapine.
Emapalumab-lzsg Injection	Emapalumab-lzsg Injection The metabolism of Mirtazapine can be increased when combined with Emapalumab.
Siponimod	Siponimod The metabolism of Siponimod can be decreased when combined with Mirtazapine.
Acyclovir Ophthalmic	Acyclovir Ophthalmic The metabolism of Acyclovir can be decreased when combined with Mirtazapine.
Erdafitinib	Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Mirtazapine.
Alpelisib	Alpelisib The metabolism of Alpelisib can be decreased when combined with Mirtazapine.
Brexanolone Injection	Brexanolone Injection Brexanolone may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Solriamfetol	Solriamfetol The risk or severity of hypertension can be increased when Solriamfetol is combined with Mirtazapine.
Triclabendazole	Triclabendazole The metabolism of Mirtazapine can be decreased when combined with Triclabendazole.
Entrectinib	Entrectinib The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Entrectinib.
Pexidartinib	Pexidartinib The metabolism of Pexidartinib can be decreased when combined with Mirtazapine.
Istradefylline	Istradefylline The metabolism of Istradefylline can be decreased when combined with Mirtazapine.
Pitolisant	Pitolisant The therapeutic efficacy of Pitolisant can be decreased when used in combination with Mirtazapine.
Fedratinib	Fedratinib The metabolism of Mirtazapine can be decreased when combined with Fedratinib.
Lefamulin	Lefamulin Lefamulin may increase the QTc-prolonging activities of Mirtazapine.
Phenytoin Injection	Phenytoin Injection Phenytoin may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Fosphenytoin Injection	Fosphenytoin Injection Fosphenytoin may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Zanubrutinib	Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Mirtazapine.
Voxelotor	Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Mirtazapine.
Lumateperone	Lumateperone Lumateperone may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Lasmiditan	Lasmiditan Lasmiditan may increase the serotonergic activities of Mirtazapine.
Ubrogepant	Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Mirtazapine.
Tazemetostat	Tazemetostat The metabolism of Tazemetostat can be decreased when combined with Mirtazapine.
Cenobamate	Cenobamate The serum concentration of Mirtazapine can be decreased when it is combined with Cenobamate.
Selumetinib	Selumetinib The metabolism of Selumetinib can be decreased when combined with Mirtazapine.
Tucatinib	Tucatinib The metabolism of Tucatinib can be decreased when combined with Mirtazapine.
Selpercatinib	Selpercatinib The risk or severity of hypertension can be increased when Mirtazapine is combined with Selpercatinib.
Capmatinib	Capmatinib The metabolism of Mirtazapine can be decreased when combined with Capmatinib.
Lemborexant	Lemborexant Lemborexant may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Daratumumab and Hyaluronidase-fihj Injection	Daratumumab and Hyaluronidase-fihj Injection The therapeutic efficacy of Hyaluronidase can be decreased when used in combination with Mirtazapine.
Fenfluramine	Fenfluramine Fenfluramine may increase the serotonergic activities of Mirtazapine.
Fostemsavir	Fostemsavir The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Fostemsavir.
Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf Injection	Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf Injection The therapeutic efficacy of Hyaluronidase can be decreased when used in combination with Mirtazapine.
Octreotide	Octreotide The risk or severity of QTc prolongation can be increased when Octreotide is combined with Mirtazapine.
Satralizumab-mwge Injection	Satralizumab-mwge Injection The serum concentration of Mirtazapine can be decreased when it is combined with Satralizumab.
Naxitamab-gqgk Injection	Naxitamab-gqgk Injection The risk or severity of hypertension can be increased when Mirtazapine is combined with Naxitamab.
Relugolix	Relugolix The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Relugolix.
Progestin-Only (drospirenone) Oral Contraceptives	Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Drospirenone can be decreased when combined with Mirtazapine.
Viloxazine	Viloxazine Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Viloxazine.
Theophylline	Theophylline The metabolism of Theophylline can be decreased when combined with Mirtazapine.
Fenoprofen	Fenoprofen The risk or severity of hypertension can be increased when Mirtazapine is combined with Fenoprofen.
Indomethacin	Indomethacin The risk or severity of hypertension can be increased when Indomethacin is combined with Mirtazapine.
Mefenamic Acid	Mefenamic Acid The risk or severity of hypertension can be increased when Mirtazapine is combined with Mefenamic acid.
Naproxen	Naproxen The metabolism of Naproxen can be decreased when combined with Mirtazapine.
Tolmetin	Tolmetin The risk or severity of hypertension can be increased when Mirtazapine is combined with Tolmetin.
Sulindac	Sulindac The risk or severity of hypertension can be increased when Mirtazapine is combined with Sulindac.
Trazodone	Trazodone Trazodone may increase the serotonergic activities of Mirtazapine.
Hydroxyurea	Hydroxyurea The metabolism of Mirtazapine can be decreased when combined with Hydroxyurea.
Phenobarbital	Phenobarbital Phenobarbital may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Metaxalone	Metaxalone Metaxalone may increase the serotonergic activities of Mirtazapine.
Methotrexate Injection	Methotrexate Injection The metabolism of Methotrexate can be decreased when combined with Mirtazapine.
Levorphanol	Levorphanol Levorphanol may increase the serotonergic activities of Mirtazapine.
Primidone	Primidone Primidone may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Methsuximide	Methsuximide Methsuximide may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Diethylpropion	Diethylpropion Diethylpropion may increase the serotonergic activities of Mirtazapine.
Chlorpromazine	Chlorpromazine Chlorpromazine may increase the serotonergic activities of Mirtazapine.
Diazepam	Diazepam The risk or severity of adverse effects can be increased when Diazepam is combined with Mirtazapine.
Oxazepam	Oxazepam Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Oxazepam.
Flurazepam	Flurazepam Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Flurazepam.
Clorazepate	Clorazepate Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Clorazepic acid.
Lorazepam	Lorazepam Lorazepam may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Phenoxybenzamine	Phenoxybenzamine The risk or severity of hypertension can be increased when Mirtazapine is combined with Phenoxybenzamine.
Carmustine	Carmustine The metabolism of Mirtazapine can be decreased when combined with Carmustine.
Amantadine	Amantadine Amantadine may increase the serotonergic activities of Mirtazapine.
Codeine	Codeine Codeine may increase the serotonergic activities of Mirtazapine.
Meprobamate	Meprobamate Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Meprobamate.
Chlordiazepoxide	Chlordiazepoxide Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Chlordiazepoxide.
Bromocriptine	Bromocriptine Mirtazapine may decrease the antihypertensive activities of Bromocriptine.
Metaproterenol	Metaproterenol The risk or severity of hypertension can be increased when Mirtazapine is combined with Orciprenaline.
Tranylcypromine	Tranylcypromine Tranylcypromine may increase the serotonergic activities of Mirtazapine.
Phenelzine	Phenelzine Phenelzine may increase the serotonergic activities of Mirtazapine.
Procarbazine	Procarbazine Procarbazine may increase the serotonergic activities of Mirtazapine.
Ergoloid Mesylates	Ergoloid Mesylates Ergoloid mesylate may increase the serotonergic activities of Mirtazapine.
Minocycline	Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Prochlorperazine	Prochlorperazine Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Prochlorperazine.
Thioridazine	Thioridazine Thioridazine may increase the serotonergic activities of Mirtazapine.
Trifluoperazine	Trifluoperazine Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Trifluoperazine.
Oxycodone	Oxycodone Oxycodone may increase the serotonergic activities of Mirtazapine.
Methadone	Methadone Methadone may increase the serotonergic activities of Mirtazapine.
Oxybutynin	Oxybutynin The metabolism of Mirtazapine can be decreased when combined with Oxybutynin.
Benztropine	Benztropine Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Benzatropine.
Maprotiline	Maprotiline Maprotiline may increase the serotonergic activities of Mirtazapine.
Ibuprofen	Ibuprofen The risk or severity of hypertension can be increased when Mirtazapine is combined with Ibuprofen.
Trihexyphenidyl	Trihexyphenidyl Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Trihexyphenidyl.
Orphenadrine	Orphenadrine Orphenadrine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Perphenazine	Perphenazine Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Perphenazine.
Azathioprine	Azathioprine The metabolism of Azathioprine can be decreased when combined with Mirtazapine.
Fluphenazine	Fluphenazine Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Fluphenazine.
Phentermine	Phentermine Phentermine may increase the serotonergic activities of Mirtazapine.
Methylphenidate	Methylphenidate The risk or severity of hypertension can be increased when Mirtazapine is combined with Methylphenidate.
Amoxapine	Amoxapine Amoxapine may increase the serotonergic activities of Mirtazapine.
Sulfasalazine	Sulfasalazine The risk or severity of hypertension can be increased when Mirtazapine is combined with Sulfasalazine.
Doxorubicin	Doxorubicin The metabolism of Mirtazapine can be decreased when combined with Doxorubicin.
Carbamazepine	Carbamazepine Carbamazepine may increase the serotonergic activities of Mirtazapine.
Molindone	Molindone Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Molindone.
Methyldopa	Methyldopa Mirtazapine may decrease the antihypertensive activities of Methyldopa.
Clonidine	Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Mirtazapine.
Prazosin	Prazosin Mirtazapine may decrease the antihypertensive activities of Prazosin.
Hydralazine	Hydralazine Mirtazapine may decrease the antihypertensive activities of Hydralazine.
Cimetidine	Cimetidine The metabolism of Mirtazapine can be decreased when combined with Cimetidine.
Warfarin	Warfarin Mirtazapine may increase the anticoagulant activities of Warfarin.
Clonazepam	Clonazepam Clonazepam may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Loperamide	Loperamide The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Loperamide.
Promethazine	Promethazine Promethazine may increase the serotonergic activities of Mirtazapine.
Meclofenamate	Meclofenamate The risk or severity of hypertension can be increased when Mirtazapine is combined with Meclofenamic acid.
Griseofulvin	Griseofulvin The metabolism of Mirtazapine can be increased when combined with Griseofulvin.
Digoxin	Digoxin The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Digoxin.
Loxapine	Loxapine Loxapine may increase the serotonergic activities of Mirtazapine.
Chloroquine	Chloroquine The metabolism of Chloroquine can be decreased when combined with Mirtazapine.
Quinine	Quinine Quinine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Ethosuximide	Ethosuximide Ethosuximide may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Triamterene	Triamterene The metabolism of Triamterene can be decreased when combined with Mirtazapine.
Chlorothiazide	Chlorothiazide Mirtazapine may decrease the antihypertensive activities of Chlorothiazide.
Chlorthalidone	Chlorthalidone Mirtazapine may decrease the antihypertensive activities of Chlorthalidone.
Metolazone	Metolazone Mirtazapine may decrease the antihypertensive activities of Metolazone.
Secobarbital	Secobarbital Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Desipramine	Desipramine Desipramine may increase the serotonergic activities of Mirtazapine.
Amitriptyline	Amitriptyline Amitriptyline may increase the serotonergic activities of Mirtazapine.
Imipramine	Imipramine Imipramine may increase the serotonergic activities of Mirtazapine.
Quinidine	Quinidine The metabolism of Quinidine can be decreased when combined with Mirtazapine.
Procainamide	Procainamide The metabolism of Procainamide can be decreased when combined with Mirtazapine.
Isoniazid	Isoniazid Isoniazid may increase the serotonergic activities of Mirtazapine.
Rifampin	Rifampin The metabolism of Mirtazapine can be increased when combined with Rifampicin.
Disopyramide	Disopyramide The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Disopyramide.
Valproic Acid	Valproic Acid Valproic acid may increase the serotonergic activities of Mirtazapine.
Tamoxifen	Tamoxifen The metabolism of Mirtazapine can be decreased when combined with Tamoxifen.
Butabarbital	Butabarbital Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Levothyroxine	Levothyroxine The risk or severity of adverse effects can be increased when Mirtazapine is combined with Levothyroxine.
Methimazole	Methimazole The metabolism of Mirtazapine can be decreased when combined with Methimazole.
Dextromethorphan	Dextromethorphan Dextromethorphan may increase the serotonergic activities of Mirtazapine.
Cyclobenzaprine	Cyclobenzaprine Cyclobenzaprine may increase the serotonergic activities of Mirtazapine.
Niacin	Niacin The metabolism of Mirtazapine can be decreased when combined with Niacin.
Baclofen	Baclofen Baclofen may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Doxylamine	Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Cyproheptadine	Cyproheptadine Cyproheptadine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Clemastine	Clemastine Clemastine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Chlorpheniramine	Chlorpheniramine Chlorpheniramine may increase the serotonergic activities of Mirtazapine.
Brompheniramine	Brompheniramine Dexbrompheniramine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Meclizine	Meclizine Meclizine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Hydrochlorothiazide	Hydrochlorothiazide The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Hydrochlorothiazide.
Dantrolene	Dantrolene Dantrolene may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Chlorzoxazone	Chlorzoxazone Chlorzoxazone may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Carisoprodol	Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Mirtazapine.
Methocarbamol	Methocarbamol Methocarbamol may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Disulfiram	Disulfiram The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Disulfiram.
Propranolol (Cardiovascular)	Propranolol (Cardiovascular) The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Propranolol.
Minoxidil	Minoxidil Mirtazapine may decrease the antihypertensive activities of Minoxidil.
Pseudoephedrine	Pseudoephedrine Pseudoephedrine may increase the serotonergic activities of Mirtazapine.
Nortriptyline	Nortriptyline Nortriptyline may increase the serotonergic activities of Mirtazapine.
Nadolol	Nadolol The metabolism of Nadolol can be decreased when combined with Mirtazapine.
Butorphanol Injection	Butorphanol Injection Butorphanol may increase the serotonergic activities of Mirtazapine.
Nalbuphine Injection	Nalbuphine Injection Nalbuphine may increase the serotonergic activities of Mirtazapine.
Oxytocin Injection	Oxytocin Injection The risk or severity of QTc prolongation can be increased when Oxytocin is combined with Mirtazapine.
Trimethobenzamide	Trimethobenzamide Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Flavoxate	Flavoxate Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Flavoxate.
Papaverine	Papaverine The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Papaverine.
Fluorouracil Injection	Fluorouracil Injection The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Fluorouracil.
Colchicine	Colchicine The metabolism of Colchicine can be decreased when combined with Mirtazapine.
Cephalexin	Cephalexin The metabolism of Cephalexin can be decreased when combined with Mirtazapine.
Dacarbazine	Dacarbazine The metabolism of Dacarbazine can be decreased when combined with Mirtazapine.
Acetazolamide	Acetazolamide Acetazolamide may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Ketoconazole	Ketoconazole The metabolism of Mirtazapine can be decreased when combined with Ketoconazole.
Pyrantel	Pyrantel Pyrantel may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Thiotepa Injection	Thiotepa Injection The metabolism of Thiotepa can be decreased when combined with Mirtazapine.
Vincristine Injection	Vincristine Injection The metabolism of Vincristine can be decreased when combined with Mirtazapine.
Captopril	Captopril Mirtazapine may decrease the antihypertensive activities of Captopril.
Isoxsuprine	Isoxsuprine The risk or severity of hypertension can be increased when Mirtazapine is combined with Isoxsuprine.
Vinblastine	Vinblastine The metabolism of Mirtazapine can be decreased when combined with Vinblastine.
Metoprolol	Metoprolol The metabolism of Mirtazapine can be decreased when combined with Metoprolol.
Hydroxyzine	Hydroxyzine The risk or severity of QTc prolongation can be increased when Hydroxyzine is combined with Mirtazapine.
Thiothixene	Thiothixene Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Thiothixene.
Aspirin	Aspirin The risk or severity of hypertension can be increased when Mirtazapine is combined with Acetylsalicylic acid.
Salsalate	Salsalate The risk or severity of hypertension can be increased when Mirtazapine is combined with Salsalate.
Alprazolam	Alprazolam The metabolism of Alprazolam can be decreased when combined with Mirtazapine.
Temazepam	Temazepam Temazepam may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Triazolam	Triazolam Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Triazolam.
Dicyclomine	Dicyclomine Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine.
Hyoscyamine	Hyoscyamine Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine.
Propantheline	Propantheline Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Propantheline.
Diltiazem	Diltiazem The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Diltiazem.
Nifedipine	Nifedipine The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Nifedipine.
Timolol	Timolol The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Timolol.
Verapamil	Verapamil The metabolism of Verapamil can be decreased when combined with Mirtazapine.
Atenolol	Atenolol The metabolism of Mirtazapine can be decreased when combined with Atenolol.
Pindolol	Pindolol Pindolol may increase the serotonergic activities of Mirtazapine.
Diflunisal	Diflunisal The risk or severity of hypertension can be increased when Mirtazapine is combined with Diflunisal.
Piroxicam	Piroxicam The risk or severity of hypertension can be increased when Mirtazapine is combined with Piroxicam.
Streptozocin	Streptozocin The metabolism of Mirtazapine can be increased when combined with Streptozocin.
Etoposide	Etoposide The metabolism of Etoposide can be decreased when combined with Mirtazapine.
Indapamide	Indapamide The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Indapamide.
Nafcillin Injection	Nafcillin Injection The metabolism of Mirtazapine can be increased when combined with Nafcillin.
Pentoxifylline	Pentoxifylline The metabolism of Pentoxifylline can be decreased when combined with Mirtazapine.
Pentamidine Injection	Pentamidine Injection The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Pentamidine.
Labetalol	Labetalol The metabolism of Mirtazapine can be decreased when combined with Labetalol.
Leuprolide Injection	Leuprolide Injection The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Leuprolide.
Gemfibrozil	Gemfibrozil The metabolism of Mirtazapine can be decreased when combined with Gemfibrozil.
Guanabenz	Guanabenz Mirtazapine may decrease the antihypertensive activities of Guanabenz.
Ketoprofen	Ketoprofen The risk or severity of hypertension can be increased when Mirtazapine is combined with Ketoprofen.
Pimozide	Pimozide Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Pimozide.
Enalapril	Enalapril Mirtazapine may decrease the antihypertensive activities of Enalapril.
Flurbiprofen	Flurbiprofen The risk or severity of hypertension can be increased when Mirtazapine is combined with Flurbiprofen.
Amiodarone	Amiodarone The metabolism of Amiodarone can be decreased when combined with Mirtazapine.
Buspirone	Buspirone Buspirone may increase the serotonergic activities of Mirtazapine.
Lovastatin	Lovastatin The metabolism of Lovastatin can be decreased when combined with Mirtazapine.
Ciprofloxacin	Ciprofloxacin The metabolism of Mirtazapine can be decreased when combined with Ciprofloxacin.
Mesalamine	Mesalamine The risk or severity of hypertension can be increased when Mesalazine is combined with Mirtazapine.
Diclofenac	Diclofenac The metabolism of Diclofenac can be decreased when combined with Mirtazapine.
Fluoxetine	Fluoxetine Fluoxetine may increase the serotonergic activities of Mirtazapine.
Nimodipine	Nimodipine The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Nimodipine.
Interferon Alfa-2b Injection	Interferon Alfa-2b Injection The metabolism of Mirtazapine can be decreased when combined with Interferon alfa-2b.
Clozapine	Clozapine Clozapine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Estazolam	Estazolam Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Estazolam.
Idarubicin	Idarubicin The metabolism of Idarubicin can be decreased when combined with Mirtazapine.
Ofloxacin	Ofloxacin The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Ofloxacin.
Clarithromycin	Clarithromycin The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Clarithromycin.
Benazepril	Benazepril Mirtazapine may decrease the antihypertensive activities of Benazepril.
Etodolac	Etodolac The risk or severity of hypertension can be increased when Mirtazapine is combined with Etodolac.
Felodipine	Felodipine The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Felodipine.
Fosinopril	Fosinopril Mirtazapine may decrease the antihypertensive activities of Fosinopril.
Nabumetone	Nabumetone The metabolism of Nabumetone can be decreased when combined with Mirtazapine.
Quinapril	Quinapril Mirtazapine may decrease the antihypertensive activities of Quinapril.
Ramipril	Ramipril Mirtazapine may decrease the antihypertensive activities of Ramipril.
Simvastatin	Simvastatin The metabolism of Simvastatin can be decreased when combined with Mirtazapine.
Amlodipine	Amlodipine Mirtazapine may decrease the antihypertensive activities of Amlodipine.
Teniposide Injection	Teniposide Injection The metabolism of Teniposide can be decreased when combined with Mirtazapine.
Itraconazole	Itraconazole The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Itraconazole.
Lisinopril	Lisinopril Mirtazapine may decrease the antihypertensive activities of Lisinopril.
Oxaprozin	Oxaprozin The risk or severity of hypertension can be increased when Mirtazapine is combined with Oxaprozin.
Sotalol	Sotalol The metabolism of Sotalol can be decreased when combined with Mirtazapine.
Bisoprolol	Bisoprolol Mirtazapine may decrease the antihypertensive activities of Bisoprolol.
Zolpidem	Zolpidem Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Doxazosin	Doxazosin The metabolism of Doxazosin can be decreased when combined with Mirtazapine.
Terazosin	Terazosin Mirtazapine may decrease the antihypertensive activities of Terazosin.
Isradipine	Isradipine The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Isradipine.
Omeprazole	Omeprazole The metabolism of Mirtazapine can be increased when combined with Omeprazole.
Cisapride	Cisapride Cisapride may increase the serotonergic activities of Mirtazapine.
Gabapentin	Gabapentin Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
Fluvastatin	Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Mirtazapine.
Venlafaxine	Venlafaxine Venlafaxine may increase the serotonergic activities of Mirtazapine.
Famciclovir	Famciclovir The metabolism of Famciclovir can be decreased when combined with Mirtazapine.
Fluvoxamine	Fluvoxamine Fluvoxamine may increase the serotonergic activities of Mirtazapine.
Nefazodone	Nefazodone Nefazodone may increase the serotonergic activities of Mirtazapine.
Lamotrigine	Lamotrigine Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Lamotrigine.
Losartan	Losartan The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Losartan.
Tramadol	Tramadol Tramadol may increase the serotonergic activities of Mirtazapine.
Vinorelbine Injection	Vinorelbine Injection The metabolism of Mirtazapine can be decreased when combined with Vinorelbine.
Moexipril	Moexipril The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Moexipril.
Lansoprazole	Lansoprazole The metabolism of Mirtazapine can be decreased when combined with Lansoprazole.
Ifosfamide Injection	Ifosfamide Injection The metabolism of Ifosfamide can be decreased when combined with Mirtazapine.
Nicardipine	Nicardipine The metabolism of Mirtazapine can be decreased when combined with Nicardipine.
Bupropion	Bupropion Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Bupropion.
Ticlopidine	Ticlopidine The metabolism of Mirtazapine can be decreased when combined with Ticlopidine.
Saquinavir	Saquinavir The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Saquinavir.
Nisoldipine	Nisoldipine Mirtazapine may decrease the antihypertensive activities of Nisoldipine.
Riluzole	Riluzole Riluzole may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Ritonavir	Ritonavir The serum concentration of Mirtazapine can be increased when it is combined with Ritonavir.
Docetaxel Injection	Docetaxel Injection The metabolism of Docetaxel can be decreased when combined with Mirtazapine.
Clomipramine	Clomipramine Clomipramine may increase the serotonergic activities of Mirtazapine.
Zafirlukast	Zafirlukast The metabolism of Mirtazapine can be decreased when combined with Zafirlukast.
Trandolapril	Trandolapril Mirtazapine may decrease the antihypertensive activities of Trandolapril.
Topiramate	Topiramate Topiramate may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Zileuton	Zileuton The metabolism of Zileuton can be decreased when combined with Mirtazapine.
Valsartan	Valsartan Mirtazapine may decrease the antihypertensive activities of Valsartan.
Insulin Lispro Injection	Insulin Lispro Injection The metabolism of Mirtazapine can be increased when combined with Insulin lispro.
Pramipexole	Pramipexole Mirtazapine may increase the sedative activities of Pramipexole.
Donepezil	Donepezil Donepezil may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nelfinavir	Nelfinavir The metabolism of Nelfinavir can be decreased when combined with Mirtazapine.
Azithromycin	Azithromycin The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Azithromycin.
Carvedilol	Carvedilol The metabolism of Carvedilol can be decreased when combined with Mirtazapine.
Flutamide	Flutamide The metabolism of Flutamide can be decreased when combined with Mirtazapine.
Selegiline	Selegiline Selegiline may increase the serotonergic activities of Mirtazapine.
Bicalutamide	Bicalutamide The metabolism of Mirtazapine can be decreased when combined with Bicalutamide.
Sertraline	Sertraline Sertraline may increase the serotonergic activities of Mirtazapine.
Propafenone	Propafenone The metabolism of Mirtazapine can be decreased when combined with Propafenone.
Irbesartan	Irbesartan Mirtazapine may decrease the antihypertensive activities of Irbesartan.
Tamsulosin	Tamsulosin The metabolism of Tamsulosin can be decreased when combined with Mirtazapine.
Ropinirole	Ropinirole Ropinirole may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Finasteride	Finasteride The risk or severity of hypertension can be increased when Mirtazapine is combined with Finasteride.
Quetiapine	Quetiapine Quetiapine may increase the serotonergic activities of Mirtazapine.
Cetirizine	Cetirizine Cetirizine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Paroxetine	Paroxetine Paroxetine may increase the serotonergic activities of Mirtazapine.
Tolcapone	Tolcapone Tolcapone may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Citalopram	Citalopram Citalopram may increase the serotonergic activities of Mirtazapine.
Efavirenz	Efavirenz Efavirenz may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Sildenafil	Sildenafil The metabolism of Mirtazapine can be decreased when combined with Sildenafil.
Celecoxib	Celecoxib The metabolism of Mirtazapine can be decreased when combined with Celecoxib.
Rosiglitazone	Rosiglitazone The metabolism of Mirtazapine can be decreased when combined with Rosiglitazone.
Tolterodine	Tolterodine Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine.
Thalidomide	Thalidomide Mirtazapine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Balsalazide	Balsalazide The risk or severity of hypertension can be increased when Mirtazapine is combined with Balsalazide.
Nateglinide	Nateglinide The metabolism of Nateglinide can be decreased when combined with Mirtazapine.
Galantamine	Galantamine The risk or severity of QTc prolongation can be increased when Mirtazapine is combined with Galantamine.
Levetiracetam	Levetiracetam Levetiracetam may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Rabeprazole	Rabeprazole The metabolism of Mirtazapine can be increased when combined with Rabeprazole.
Terbinafine	Terbinafine The metabolism of Mirtazapine can be decreased when combined with Terbinafine.