Olanzapine

Olanzapine is used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions) in adults and teenagers 13 years of age and older. It is also used to treat bipolar disorder (manic depressive disorder; a disease that causes episodes of depression, episodes of mania, and other abnormal moods) in adults and teenagers 13 years of age and older. Olanzapine is in a class of medications called atypical antipsychotics. It works by changing the activity of certain natural substances in the brain.

Olanzapine comes as a tablet and an orally disintegrating tablet (tablet that dissolves quickly in the mouth) to take by mouth. It is usually taken once a day with or without food. Take olanzapine at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take olanzapine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Do not try to push the orally disintegrating tablet through the foil. Instead, use dry hands to peel back the foil packaging. Immediately take out the tablet and place it in your mouth. The tablet will quickly dissolve and can be swallowed with or without liquid.

Your doctor may start you on a low dose of olanzapine and gradually increase your dose.

Olanzapine may help control your symptoms, but it will not cure your condition. It may take several weeks or longer before you feel the full benefit of olanzapine. Continue to take olanzapine even if you feel well. Do not stop taking olanzapine without talking to your doctor. Your doctor will probably want to decrease your dose gradually.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking olanzapine,

• tell your doctor and pharmacist if you are allergic to olanzapine or any other medications.

• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antidepressants; antihistamines; carbamazepine (Tegretol); dopamine agonists such as bromocriptine (Parlodel), cabergoline (Dostinex), levodopa (Dopar, Larodopa), pergolide (Permax), and ropinirole (Requip); fluoroquinolone antibiotics including ciprofloxacin (Cipro), gatifloxacin (Tequin) (not available in the United States), levofloxacin (Levaquin), norfloxacin (Noroxin), ofloxacin (Floxin), others; fluvoxamine (Luvox); ipratropium (Atrovent); medications for anxiety, high blood pressure, irritable bowel disease, mental illness, motion sickness, Parkinson's disease, seizures, ulcers, or urinary problems; omeprazole (Prilosec); rifampin (Rifadin); sedatives; sleeping pills; ticlopidine (Ticlid); and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

• tell your doctor if you use or have ever used street drugs or have overused prescription medications and if you have or have ever had a stroke, a mini-stroke, heart disease or a heart attack, an irregular heartbeat, heart failure, urinary problems, seizures, breast cancer, any condition that makes it difficult for you to swallow, trouble keeping your balance, high or low blood pressure, a high level of fats (cholesterol and triglycerides) in your blood, a low number of white blood cells, liver or prostate disease, paralytic ileus (condition in which food cannot move through the intestine); glaucoma (an eye condition), or high blood sugar, or if you or anyone in your family has or has ever had diabetes. Tell your doctor if you have constipation, severe vomiting or diarrhea or signs of dehydration now, or if you develop these symptoms at any time during your treatment. Also tell your doctor if you have ever had to stop taking a medication for mental illness because of severe side effects.

• tell your doctor if you are pregnant, especially if you are in the last few months of your pregnancy, or if you plan to become pregnant or are breastfeeding. If you become pregnant while taking olanzapine, call your doctor. Olanzapine may cause problems in newborns following delivery if it is taken during the last months of pregnancy.

• if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking olanzapine.

• you should know that olanzapine may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.

• you should know that alcohol can add to the drowsiness caused by this medication. Do not drink alcohol while taking olanzapine.

• tell your doctor if you use tobacco products. Cigarette smoking may decrease the effectiveness of this medication.

• you should know that you may experience hyperglycemia (increases in your blood sugar) while you are taking this medication, even if you do not already have diabetes. If you have schizophrenia, you are more likely to develop diabetes than people who do not have schizophrenia, and taking olanzapine or similar medications may increase this risk. Tell your doctor immediately if you have any of the following symptoms while you are taking olanzapine: extreme thirst, frequent urination, extreme hunger, blurred vision, or weakness. It is very important to call your doctor as soon as you have any of these symptoms, because high blood sugar can cause a serious condition called ketoacidosis. Ketoacidosis may become life-threatening if it is not treated at an early stage. Symptoms of ketoacidosis include: dry mouth, nausea and vomiting, shortness of breath, breath that smells fruity, and decreased consciousness.

• you should know that olanzapine may cause fast or slow heartbeat, dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common when you first start taking olanzapine. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.

• you should know that olanzapine may make it harder for your body to cool down when it gets very hot. Tell your doctor if you plan to do vigorous exercise or be exposed to extreme heat.

• if you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent damage to your brain that can cause severe intellectual disability), you should know that the orally disintegrating tablets contain aspartame that forms phenylalanine.

• you should know that when olanzapine is used to treat teenagers, it must be used as part of a total treatment program that may include counseling and educational support. Make sure that your child follows all of the doctor's and/or therapist's instructions.

Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medicine.

Be sure to drink plenty of water every day while you are taking this medication.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

• Olanzapine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • dizziness, feeling unsteady, or having trouble keeping your balance

  • restlessness

  • unusual behavior

  • depression

  • difficulty falling asleep or staying asleep

  • weakness

  • difficulty walking

  • constipation

  • weight gain

  • dry mouth

  • pain in arms, legs, back, or joints

  • breast enlargement or discharge

  • late or missed menstrual periods

  • decreased sexual ability

• Some side effects can be serious. If you experience any of the following symptoms or those listed in the IMPORTANT WARNING section or the SPECIAL PRECAUTIONS section, call your doctor immediately:

  • seizures

  • changes in vision

  • swelling of the arms, hands, feet, ankles, or lower legs

  • unusual movements of your face or body that you cannot control

  • falling

  • sore throat, fever, chills, and other signs of infection

  • very stiff muscles

  • excess sweating

  • fast or irregular heartbeat

  • rash that may occur with fever, swollen glands, or swelling of the face

  • skin redness or peeling

  • hives

  • difficulty breathing or swallowing

• Olanzapine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

• Taking olanzapine may cause the level of fats in your blood to increase. Talk to your doctor about the risks of taking olanzapine.

• Teenagers who take olanzapine are more likely than adults who take olanzapine to gain weight, have increased levels of fat in their blood, develop liver problems, and experience side effects such as sleepiness, breast enlargement, and discharge from the breasts. Talk to your child's doctor about the risks of treating your child with olanzapine. Your child's doctor may choose to first prescribe a different medication that does not have these risks.

• If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Always store the orally disintegrating tablets in their sealed package, and use them immediately after opening the package.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include:

• drowsiness

• slurred speech

• agitation

• fast heartbeat

• sudden movements that you cannot control

• coma (loss of consciousness for a period of time)

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to olanzapine.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

• Symbyax^® (containing Fluoxetine, Olanzapine )

Drug	Interaction
Moxifloxacin	Moxifloxacin The metabolism of Olanzapine can be decreased when combined with Moxifloxacin.
Repaglinide	Repaglinide The therapeutic efficacy of Repaglinide can be decreased when used in combination with Olanzapine.
Montelukast	Montelukast The metabolism of Montelukast can be decreased when combined with Olanzapine.
Insulin Glargine (rDNA origin) Injection	Insulin Glargine (rDNA origin) Injection The therapeutic efficacy of Insulin glargine can be decreased when used in combination with Olanzapine.
Leflunomide	Leflunomide The serum concentration of Olanzapine can be decreased when it is combined with Leflunomide.
Delavirdine	Delavirdine Olanzapine can cause a decrease in the absorption of Delavirdine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Nevirapine	Nevirapine The metabolism of Nevirapine can be decreased when combined with Olanzapine.
Dolasetron	Dolasetron The risk or severity of adverse effects can be increased when Olanzapine is combined with Dolasetron.
Aminophylline	Aminophylline The metabolism of Aminophylline can be decreased when combined with Olanzapine.
Anagrelide	Anagrelide The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Anagrelide.
Bisacodyl	Bisacodyl The therapeutic efficacy of Bisacodyl can be decreased when used in combination with Olanzapine.
Candesartan	Candesartan The metabolism of Candesartan can be decreased when combined with Olanzapine.
Cilostazol	Cilostazol The serum concentration of Cilostazol can be increased when it is combined with Olanzapine.
Clopidogrel	Clopidogrel The metabolism of Clopidogrel can be decreased when combined with Olanzapine.
Diphenoxylate	Diphenoxylate The risk or severity of adverse effects can be increased when Diphenoxylate is combined with Olanzapine.
Erythromycin and Sulfisoxazole	Erythromycin and Sulfisoxazole The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives)	Estrogen and Progestin (Oral Contraceptives) The metabolism of Olanzapine can be decreased when combined with Conjugated estrogens.
Guanfacine	Guanfacine The risk or severity of adverse effects can be increased when Olanzapine is combined with Guanfacine.
Magnesium Hydroxide	Magnesium Hydroxide The therapeutic efficacy of Magnesium hydroxide can be decreased when used in combination with Olanzapine.
Magnesium Oxide	Magnesium Oxide The therapeutic efficacy of Magnesium oxide can be decreased when used in combination with Olanzapine.
Miglitol	Miglitol The therapeutic efficacy of Miglitol can be decreased when used in combination with Olanzapine.
Naratriptan	Naratriptan The risk or severity of adverse effects can be increased when Olanzapine is combined with Naratriptan.
Paregoric	Paregoric The risk or severity of adverse effects can be increased when Morphine is combined with Olanzapine.
Penbutolol	Penbutolol The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Acebutolol.
Pentazocine	Pentazocine The risk or severity of adverse effects can be increased when Pentazocine is combined with Olanzapine.
Polyethylene glycol-electrolyte solution (PEG-ES)	Polyethylene glycol-electrolyte solution (PEG-ES) The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Olanzapine.
Psyllium	Psyllium The therapeutic efficacy of Plantago seed can be decreased when used in combination with Olanzapine.
Ranitidine	Ranitidine The metabolism of Ranitidine can be decreased when combined with Olanzapine.
Reserpine	Reserpine The risk or severity of adverse effects can be increased when Reserpine is combined with Olanzapine.
Rizatriptan	Rizatriptan The risk or severity of adverse effects can be increased when Olanzapine is combined with Rizatriptan.
Sumatriptan	Sumatriptan Sumatriptan may increase the central nervous system depressant (CNS depressant) activities of Olanzapine.
Tacrolimus	Tacrolimus The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Tacrolimus.
Tizanidine	Tizanidine The risk or severity of adverse effects can be increased when Olanzapine is combined with Tizanidine.
Zolmitriptan	Zolmitriptan The metabolism of Olanzapine can be decreased when combined with Zolmitriptan.
Famotidine Injection	Famotidine Injection The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Famotidine.
Fluconazole Injection	Fluconazole Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Olanzapine.
Foscarnet Injection	Foscarnet Injection The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Foscarnet.
Hydromorphone Injection	Hydromorphone Injection The risk or severity of adverse effects can be increased when Hydromorphone is combined with Olanzapine.
Interferon Beta-1b Injection	Interferon Beta-1b Injection The metabolism of Olanzapine can be decreased when combined with Interferon beta-1b.
Interferon Gamma-1b Injection	Interferon Gamma-1b Injection The metabolism of Olanzapine can be decreased when combined with Interferon gamma-1b.
Levofloxacin Injection	Levofloxacin Injection The metabolism of Olanzapine can be decreased when combined with Levofloxacin.
Meperidine Injection	Meperidine Injection The risk or severity of adverse effects can be increased when Meperidine is combined with Olanzapine.
Metoclopramide Injection	Metoclopramide Injection The risk or severity of adverse effects can be increased when Metoclopramide is combined with Olanzapine.
Metronidazole Injection	Metronidazole Injection The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Metronidazole.
Morphine Injection	Morphine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Olanzapine.
Zidovudine Injection	Zidovudine Injection The metabolism of Zidovudine can be decreased when combined with Olanzapine.
Altretamine	Altretamine Amphetamine may decrease the sedative and stimulatory activities of Olanzapine.
Cefuroxime	Cefuroxime Olanzapine can cause a decrease in the absorption of Cefuroxime resulting in a reduced serum concentration and potentially a decrease in efficacy.
Cyclosporine	Cyclosporine The metabolism of Olanzapine can be decreased when combined with Cyclosporine.
Ondansetron	Ondansetron The risk or severity of adverse effects can be increased when Olanzapine is combined with Ondansetron.
Granisetron	Granisetron The risk or severity of adverse effects can be increased when Olanzapine is combined with Granisetron.
Torsemide	Torsemide The risk or severity of adverse effects can be increased when Olanzapine is combined with Torasemide.
Alosetron	Alosetron The metabolism of Olanzapine can be decreased when combined with Alosetron.
Dofetilide	Dofetilide The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Dofetilide.
Entacapone	Entacapone The therapeutic efficacy of Entacapone can be decreased when used in combination with Olanzapine.
Eprosartan	Eprosartan The risk or severity of adverse effects can be increased when Olanzapine is combined with Eprosartan.
Hydroxychloroquine	Hydroxychloroquine The metabolism of Olanzapine can be decreased when combined with Hydroxychloroquine.
Meloxicam	Meloxicam The metabolism of Meloxicam can be decreased when combined with Olanzapine.
Oxcarbazepine	Oxcarbazepine The risk or severity of adverse effects can be increased when Olanzapine is combined with Oxcarbazepine.
Pantoprazole	Pantoprazole The metabolism of Pantoprazole can be decreased when combined with Olanzapine.
Risedronate	Risedronate Olanzapine can cause an increase in the absorption of Risedronic acid resulting in an increased serum concentration and potentially a worsening of adverse effects.
Telmisartan	Telmisartan The risk or severity of adverse effects can be increased when Olanzapine is combined with Telmisartan.
Zaleplon	Zaleplon The risk or severity of adverse effects can be increased when Olanzapine is combined with Zaleplon.
Anakinra	Anakinra The metabolism of Olanzapine can be increased when combined with Anakinra.
Desloratadine	Desloratadine Desloratadine may increase the central nervous system depressant (CNS depressant) activities of Olanzapine.
Linezolid	Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Olanzapine.
Rivastigmine	Rivastigmine The therapeutic efficacy of Olanzapine can be decreased when used in combination with Rivastigmine.
Trimipramine	Trimipramine Trimipramine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Olanzapine.
Etanercept Injection	Etanercept Injection The metabolism of Olanzapine can be increased when combined with Etanercept.
Glycopyrrolate	Glycopyrrolate The risk or severity of adverse effects can be increased when Olanzapine is combined with Glycopyrronium.
Modafinil	Modafinil The metabolism of Olanzapine can be increased when combined with Modafinil.
Perindopril	Perindopril The risk or severity of adverse effects can be increased when Olanzapine is combined with Perindopril.
Epinephrine Injection	Epinephrine Injection The therapeutic efficacy of Epinephrine can be decreased when used in combination with Olanzapine.
Eplerenone	Eplerenone The risk or severity of adverse effects can be increased when Olanzapine is combined with Eplerenone.
Escitalopram	Escitalopram The risk or severity of serotonin syndrome can be increased when Olanzapine is combined with Escitalopram.
Olmesartan	Olmesartan The risk or severity of adverse effects can be increased when Olanzapine is combined with Olmesartan.
Zonisamide	Zonisamide The risk or severity of adverse effects can be increased when Olanzapine is combined with Zonisamide.
Adalimumab Injection	Adalimumab Injection The metabolism of Olanzapine can be increased when combined with Adalimumab.
Aripiprazole	Aripiprazole Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole.
Atomoxetine	Atomoxetine Atomoxetine may increase the central nervous system depressant (CNS depressant) activities of Olanzapine.
Dexmethylphenidate	Dexmethylphenidate The therapeutic efficacy of Dexmethylphenidate can be decreased when used in combination with Olanzapine.
Atazanavir	Atazanavir Olanzapine can cause a decrease in the absorption of Atazanavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Almotriptan	Almotriptan The risk or severity of adverse effects can be increased when Olanzapine is combined with Almotriptan.
Eletriptan	Eletriptan Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Eletriptan.
Mefloquine	Mefloquine The risk or severity of QTc prolongation can be increased when Mefloquine is combined with Olanzapine.
Polyethylene Glycol 3350	Polyethylene Glycol 3350 The therapeutic efficacy of Polyethylene glycol can be decreased when used in combination with Olanzapine.
Rosuvastatin	Rosuvastatin The metabolism of Rosuvastatin can be decreased when combined with Olanzapine.
Vardenafil	Vardenafil The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Vardenafil.
Alfuzosin	Alfuzosin Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Alfuzosin.
Interferon Beta-1a Subcutaneous Injection	Interferon Beta-1a Subcutaneous Injection The metabolism of Olanzapine can be decreased when combined with Interferon beta-1a.
Memantine	Memantine The therapeutic efficacy of Olanzapine can be decreased when used in combination with Memantine.
Tegaserod	Tegaserod The metabolism of Olanzapine can be decreased when combined with Tegaserod.
Tadalafil	Tadalafil The risk or severity of hypotension, dyspepsia, and headache can be increased when Olanzapine is combined with Tadalafil.
Fosamprenavir	Fosamprenavir Olanzapine can cause a decrease in the absorption of Fosamprenavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Frovatriptan	Frovatriptan The metabolism of Frovatriptan can be decreased when combined with Olanzapine.
Gemifloxacin	Gemifloxacin The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Gemifloxacin.
Progesterone	Progesterone The metabolism of Progesterone can be decreased when combined with Olanzapine.
Apomorphine Injection	Apomorphine Injection The therapeutic efficacy of Apomorphine can be decreased when used in combination with Olanzapine.
Infliximab Injection	Infliximab Injection The metabolism of Olanzapine can be increased when combined with Infliximab.
Protriptyline	Protriptyline Protriptyline may increase the central nervous system depressant (CNS depressant) activities of Olanzapine.
Duloxetine	Duloxetine The risk or severity of orthostatic hypotension and syncope can be increased when Olanzapine is combined with Duloxetine.
Trospium	Trospium Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Trospium.
Bosentan	Bosentan The metabolism of Bosentan can be decreased when combined with Olanzapine.
Cinacalcet	Cinacalcet The metabolism of Olanzapine can be decreased when combined with Cinacalcet.
Erlotinib	Erlotinib Olanzapine can cause a decrease in the absorption of Erlotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Eszopiclone	Eszopiclone The risk or severity of CNS depression can be increased when Olanzapine is combined with Eszopiclone.
Insulin Aspart (rDNA Origin) Injection	Insulin Aspart (rDNA Origin) Injection The therapeutic efficacy of Insulin aspart can be decreased when used in combination with Olanzapine.
Solifenacin	Solifenacin Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Voriconazole	Voriconazole The metabolism of Voriconazole can be decreased when combined with Olanzapine.
Dextroamphetamine	Dextroamphetamine Amphetamine may decrease the sedative and stimulatory activities of Olanzapine.
Entecavir	Entecavir The metabolism of Entecavir can be decreased when combined with Olanzapine.
Peginterferon Alfa-2a Injection	Peginterferon Alfa-2a Injection The metabolism of Olanzapine can be decreased when combined with Peginterferon alfa-2a.
Peginterferon Alfa-2b (PEG-Intron)	Peginterferon Alfa-2b (PEG-Intron) The serum concentration of Olanzapine can be increased when it is combined with Peginterferon alfa-2b.
Pramlintide Injection	Pramlintide Injection The risk or severity of reduced gastrointestinal motility can be increased when Pramlintide is combined with Olanzapine.
Sodium Oxybate	Sodium Oxybate Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Exenatide Injection	Exenatide Injection The therapeutic efficacy of Exenatide can be decreased when used in combination with Olanzapine.
Ibandronate	Ibandronate The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Ibandronate.
Isocarboxazid	Isocarboxazid The risk or severity of adverse effects can be increased when Olanzapine is combined with Isocarboxazid.
Ramelteon	Ramelteon The risk or severity of adverse effects can be increased when Olanzapine is combined with Ramelteon.
Darifenacin	Darifenacin The metabolism of Olanzapine can be decreased when combined with Darifenacin.
Fentanyl	Fentanyl The risk or severity of adverse effects can be increased when Fentanyl is combined with Olanzapine.
Pregabalin	Pregabalin The therapeutic efficacy of Olanzapine can be increased when used in combination with Pregabalin.
Deferasirox	Deferasirox The serum concentration of Olanzapine can be increased when it is combined with Deferasirox.
Phenylephrine	Phenylephrine The therapeutic efficacy of Phenylephrine can be decreased when used in combination with Olanzapine.
Tipranavir	Tipranavir The metabolism of Olanzapine can be decreased when combined with Tipranavir.
Felbamate	Felbamate The risk or severity of adverse effects can be increased when Olanzapine is combined with Felbamate.
Insulin Detemir (rDNA Origin) Injection	Insulin Detemir (rDNA Origin) Injection The therapeutic efficacy of Insulin detemir can be decreased when used in combination with Olanzapine.
Ranolazine	Ranolazine The serum concentration of Olanzapine can be increased when it is combined with Ranolazine.
Abatacept Injection	Abatacept Injection The metabolism of Olanzapine can be increased when combined with Abatacept.
Rasagiline	Rasagiline The metabolism of Rasagiline can be decreased when combined with Olanzapine.
Imatinib	Imatinib The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Imatinib.
Sitagliptin	Sitagliptin The therapeutic efficacy of Sitagliptin can be decreased when used in combination with Olanzapine.
Gefitinib	Gefitinib Olanzapine can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Albuterol	Albuterol The therapeutic efficacy of Salbutamol can be decreased when used in combination with Olanzapine.
Paliperidone	Paliperidone Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Paliperidone.
Bortezomib	Bortezomib The metabolism of Olanzapine can be decreased when combined with Bortezomib.
Clofarabine Injection	Clofarabine Injection The risk or severity of adverse effects can be increased when Olanzapine is combined with Clofarabine.
Insulin Glulisine (rDNA origin) Injection	Insulin Glulisine (rDNA origin) Injection The therapeutic efficacy of Insulin glulisine can be decreased when used in combination with Olanzapine.
Lubiprostone	Lubiprostone The therapeutic efficacy of Lubiprostone can be decreased when used in combination with Olanzapine.
Oxaliplatin Injection	Oxaliplatin Injection The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Oxaliplatin.
Posaconazole	Posaconazole The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Posaconazole.
Primaquine	Primaquine The metabolism of Olanzapine can be decreased when combined with Primaquine.
Aliskiren	Aliskiren The risk or severity of adverse effects can be increased when Olanzapine is combined with Aliskiren.
Pemetrexed Injection	Pemetrexed Injection The metabolism of Pemetrexed can be decreased when combined with Olanzapine.
Dimenhydrinate	Dimenhydrinate The risk or severity of adverse effects can be increased when Olanzapine is combined with Dimenhydrinate.
Lisdexamfetamine	Lisdexamfetamine Lisdexamfetamine may decrease the sedative and stimulatory activities of Olanzapine.
Nabilone	Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Olanzapine.
Vorinostat	Vorinostat The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Vorinostat.
Sorafenib	Sorafenib The metabolism of Sorafenib can be decreased when combined with Olanzapine.
Sunitinib	Sunitinib The therapeutic efficacy of Sunitinib can be decreased when used in combination with Olanzapine.
Dronabinol	Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Olanzapine.
Lapatinib	Lapatinib The metabolism of Lapatinib can be decreased when combined with Olanzapine.
Levocetirizine	Levocetirizine The risk or severity of adverse effects can be increased when Olanzapine is combined with Levocetirizine.
Dasatinib	Dasatinib Olanzapine can cause a decrease in the absorption of Dasatinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Mexiletine	Mexiletine The metabolism of Olanzapine can be decreased when combined with Mexiletine.
Armodafinil	Armodafinil The metabolism of Olanzapine can be increased when combined with Armodafinil.
Paclitaxel (with polyoxyethylated castor oil) Injection	Paclitaxel (with polyoxyethylated castor oil) Injection The therapeutic efficacy of Castor oil can be decreased when used in combination with Olanzapine.
Temsirolimus	Temsirolimus The metabolism of Olanzapine can be decreased when combined with Temsirolimus.
Nilotinib	Nilotinib Olanzapine can cause a decrease in the absorption of Nilotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Toremifene	Toremifene The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Toremifene.
Bexarotene	Bexarotene The metabolism of Bexarotene can be decreased when combined with Olanzapine.
Budesonide	Budesonide Olanzapine can cause a decrease in the absorption of Budesonide resulting in a reduced serum concentration and potentially a decrease in efficacy.
Betaine	Betaine The therapeutic efficacy of Olanzapine can be decreased when used in combination with Glycine betaine.
OnabotulinumtoxinA Injection	OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Olanzapine is combined with Botulinum toxin type A.
RimabotulinumtoxinB Injection	RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Olanzapine is combined with Botulinum Toxin Type B.
Etravirine	Etravirine The metabolism of Etravirine can be decreased when combined with Olanzapine.
Arsenic Trioxide Injection	Arsenic Trioxide Injection The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Arsenic trioxide.
Desvenlafaxine	Desvenlafaxine The risk or severity of adverse effects can be increased when Olanzapine is combined with Desvenlafaxine.
Cevimeline	Cevimeline The metabolism of Olanzapine can be decreased when combined with Cevimeline.
Nebivolol	Nebivolol Nebivolol may increase the orthostatic hypotensive activities of Olanzapine.
Tretinoin	Tretinoin The risk or severity of adverse effects can be increased when Olanzapine is combined with Tretinoin.
Bendamustine Injection	Bendamustine Injection The metabolism of Bendamustine can be decreased when combined with Olanzapine.
Flecainide	Flecainide The metabolism of Flecainide can be decreased when combined with Olanzapine.
Certolizumab Injection	Certolizumab Injection The metabolism of Olanzapine can be increased when combined with Certolizumab pegol.
Praziquantel	Praziquantel The metabolism of Praziquantel can be decreased when combined with Olanzapine.
Rufinamide	Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Olanzapine.
Silodosin	Silodosin Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Silodosin.
Midazolam	Midazolam The risk or severity of adverse effects can be increased when Midazolam is combined with Olanzapine.
Naltrexone Injection	Naltrexone Injection The risk or severity of adverse effects can be increased when Naltrexone is combined with Olanzapine.
Eltrombopag	Eltrombopag The metabolism of Eltrombopag can be decreased when combined with Olanzapine.
Milnacipran	Milnacipran The risk or severity of adverse effects can be increased when Olanzapine is combined with Milnacipran.
Dexlansoprazole	Dexlansoprazole The metabolism of Dexlansoprazole can be decreased when combined with Olanzapine.
Sodium Phosphate	Sodium Phosphate The therapeutic efficacy of Sodium phosphate, monobasic can be decreased when used in combination with Olanzapine.
Fesoterodine	Fesoterodine Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Fesoterodine.
Degarelix Injection	Degarelix Injection The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Degarelix.
Betaxolol	Betaxolol The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Betaxolol.
Iloperidone	Iloperidone Iloperidone may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Olanzapine.
Prasugrel	Prasugrel The metabolism of Prasugrel can be decreased when combined with Olanzapine.
Lacosamide	Lacosamide The risk or severity of adverse effects can be increased when Olanzapine is combined with Lacosamide.
Everolimus	Everolimus The metabolism of Olanzapine can be decreased when combined with Everolimus.
Dronedarone	Dronedarone The metabolism of Olanzapine can be decreased when combined with Dronedarone.
AbobotulinumtoxinA Injection	AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Olanzapine is combined with Botulinum toxin type A.
Palonosetron Injection	Palonosetron Injection The risk or severity of adverse effects can be increased when Olanzapine is combined with Palonosetron.
Saxagliptin	Saxagliptin The therapeutic efficacy of Saxagliptin can be decreased when used in combination with Olanzapine.
Telavancin Injection	Telavancin Injection The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Telavancin.
Romidepsin Injection	Romidepsin Injection The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Romidepsin.
Tapentadol	Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Olanzapine.
Golimumab Injection	Golimumab Injection The metabolism of Olanzapine can be increased when combined with Golimumab.
Pazopanib	Pazopanib The therapeutic efficacy of Pazopanib can be decreased when used in combination with Olanzapine.
Asenapine	Asenapine Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Asenapine.
Vigabatrin	Vigabatrin The risk or severity of adverse effects can be increased when Olanzapine is combined with Vigabatrin.
Pitavastatin	Pitavastatin The metabolism of Pitavastatin can be decreased when combined with Olanzapine.
Albendazole	Albendazole The metabolism of Albendazole can be decreased when combined with Olanzapine.
Oxymorphone	Oxymorphone The risk or severity of adverse effects can be increased when Oxymorphone is combined with Olanzapine.
Liraglutide Injection	Liraglutide Injection The therapeutic efficacy of Liraglutide can be decreased when used in combination with Olanzapine.
Tocilizumab Injection	Tocilizumab Injection The metabolism of Olanzapine can be increased when combined with Tocilizumab.
Eribulin Injection	Eribulin Injection The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Eribulin.
IncobotulinumtoxinA Injection	IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Olanzapine is combined with Botulinum toxin type A.
Lurasidone	Lurasidone Olanzapine may increase the hypotensive activities of Lurasidone.
Acetaminophen Injection	Acetaminophen Injection The metabolism of Olanzapine can be decreased when combined with Acetaminophen.
Vilazodone	Vilazodone The metabolism of Vilazodone can be decreased when combined with Olanzapine.
Denileukin Diftitox Injection	Denileukin Diftitox Injection The risk or severity of adverse effects can be increased when Aldesleukin is combined with Olanzapine.
Terbutaline Injection	Terbutaline Injection The therapeutic efficacy of Olanzapine can be decreased when used in combination with Terbutaline.
Azilsartan	Azilsartan The risk or severity of adverse effects can be increased when Olanzapine is combined with Azilsartan medoxomil.
Linagliptin	Linagliptin The therapeutic efficacy of Linagliptin can be decreased when used in combination with Olanzapine.
Rilpivirine	Rilpivirine Olanzapine can cause a decrease in the absorption of Rilpivirine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Cyclophosphamide Injection	Cyclophosphamide Injection The metabolism of Cyclophosphamide can be decreased when combined with Olanzapine.
Abiraterone	Abiraterone The serum concentration of Olanzapine can be increased when it is combined with Abiraterone.
Triptorelin Injection	Triptorelin Injection The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Triptorelin.
Vandetanib	Vandetanib The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Vandetanib.
Clobazam	Clobazam The metabolism of Clobazam can be decreased when combined with Olanzapine.
Vemurafenib	Vemurafenib The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Olanzapine.
Vismodegib	Vismodegib The metabolism of Vismodegib can be decreased when combined with Olanzapine.
Axitinib	Axitinib The metabolism of Axitinib can be decreased when combined with Olanzapine.
Crizotinib	Crizotinib The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Crizotinib.
Cabergoline	Cabergoline Cabergoline may increase the central nervous system depressant (CNS depressant) activities of Olanzapine.
Ambrisentan	Ambrisentan Olanzapine may increase the hypotensive activities of Ambrisentan.
Ezogabine	Ezogabine The risk or severity of adverse effects can be increased when Olanzapine is combined with Tiagabine.
Iloprost	Iloprost The risk or severity of adverse effects can be increased when Olanzapine is combined with Iloprost.
Enzalutamide	Enzalutamide The metabolism of Enzalutamide can be decreased when combined with Olanzapine.
Mirabegron	Mirabegron The risk or severity of urinary retention can be increased when Olanzapine is combined with Mirabegron.
Bosutinib	Bosutinib Olanzapine can cause a decrease in the absorption of Bosutinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Linaclotide	Linaclotide The therapeutic efficacy of Linaclotide can be decreased when used in combination with Olanzapine.
Teriflunomide	Teriflunomide The serum concentration of Olanzapine can be decreased when it is combined with Teriflunomide.
Lorcaserin	Lorcaserin The therapeutic efficacy of Mecasermin can be decreased when used in combination with Olanzapine.
Cabozantinib (thyroid cancer)	Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Olanzapine.
Bedaquiline	Bedaquiline The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Bedaquiline.
Alogliptin	Alogliptin The therapeutic efficacy of Alogliptin can be decreased when used in combination with Olanzapine.
Ponatinib	Ponatinib The metabolism of Ponatinib can be decreased when combined with Olanzapine.
Pomalidomide	Pomalidomide The risk or severity of adverse effects can be increased when Olanzapine is combined with Pomalidomide.
Apixaban	Apixaban The metabolism of Apixaban can be decreased when combined with Olanzapine.
Canagliflozin	Canagliflozin The therapeutic efficacy of Canagliflozin can be decreased when used in combination with Olanzapine.
Methazolamide	Methazolamide The risk or severity of adverse effects can be increased when Olanzapine is combined with Methazolamide.
Dabrafenib	Dabrafenib Olanzapine can cause a decrease in the absorption of Dabrafenib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ospemifene	Ospemifene The metabolism of Ospemifene can be decreased when combined with Olanzapine.
Levomilnacipran	Levomilnacipran The risk or severity of adverse effects can be increased when Olanzapine is combined with Levomilnacipran.
Vortioxetine	Vortioxetine The risk or severity of adverse effects can be increased when Olanzapine is combined with Vortioxetine.
Perampanel	Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Olanzapine.
Ibrutinib	Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Olanzapine.
Avanafil	Avanafil The risk or severity of hypotension, dyspepsia, and headache can be increased when Avanafil is combined with Olanzapine.
Ketorolac Injection	Ketorolac Injection The metabolism of Ketorolac can be decreased when combined with Olanzapine.
Obinutuzumab Injection	Obinutuzumab Injection The risk or severity of adverse effects can be increased when Olanzapine is combined with Obinutuzumab.
Simeprevir	Simeprevir The metabolism of Olanzapine can be decreased when combined with Simeprevir.
Dapagliflozin	Dapagliflozin The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Olanzapine.
Iron Sucrose Injection	Iron Sucrose Injection Olanzapine can cause a decrease in the absorption of Iron sucrose resulting in a reduced serum concentration and potentially a decrease in efficacy.
Apremilast	Apremilast The metabolism of Olanzapine can be increased when combined with Apremilast.
Droxidopa	Droxidopa The therapeutic efficacy of Droxidopa can be decreased when used in combination with Olanzapine.
Ceritinib	Ceritinib The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Ceritinib.
Siltuximab Injection	Siltuximab Injection The metabolism of Olanzapine can be increased when combined with Siltuximab.
Albiglutide Injection	Albiglutide Injection The therapeutic efficacy of Albiglutide can be decreased when used in combination with Olanzapine.
Eslicarbazepine	Eslicarbazepine The risk or severity of adverse effects can be increased when Olanzapine is combined with Eslicarbazepine.
Belinostat Injection	Belinostat Injection The metabolism of Olanzapine can be increased when combined with Belinostat.
Idelalisib	Idelalisib The metabolism of Olanzapine can be decreased when combined with Idelalisib.
Testosterone Injection	Testosterone Injection The metabolism of Testosterone can be decreased when combined with Olanzapine.
Oritavancin Injection	Oritavancin Injection The metabolism of Olanzapine can be decreased when combined with Oritavancin.
Empagliflozin	Empagliflozin The therapeutic efficacy of Empagliflozin can be decreased when used in combination with Olanzapine.
Hydrocodone	Hydrocodone Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Suvorexant	Suvorexant Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Dulaglutide Injection	Dulaglutide Injection The therapeutic efficacy of Dulaglutide can be decreased when used in combination with Olanzapine.
Peginterferon Beta-1a Injection	Peginterferon Beta-1a Injection The metabolism of Olanzapine can be decreased when combined with Peginterferon beta-1a.
Methamphetamine	Methamphetamine Metamfetamine may decrease the sedative and stimulatory activities of Olanzapine.
Tasimelteon	Tasimelteon The risk or severity of adverse effects can be increased when Olanzapine is combined with Tasimelteon.
Riociguat	Riociguat The risk or severity of adverse effects can be increased when Olanzapine is combined with Riociguat.
Pirfenidone	Pirfenidone The metabolism of Pirfenidone can be decreased when combined with Olanzapine.
Secukinumab Injection	Secukinumab Injection The metabolism of Olanzapine can be increased when combined with Secukinumab.
Risperidone Injection	Risperidone Injection Olanzapine may increase the hypotensive activities of Risperidone.
Insulin Human Inhalation	Insulin Human Inhalation The therapeutic efficacy of Insulin human can be decreased when used in combination with Olanzapine.
Lenvatinib	Lenvatinib The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Lenvatinib.
Naloxegol	Naloxegol The metabolism of Olanzapine can be decreased when combined with Naloxegol.
Panobinostat	Panobinostat The metabolism of Olanzapine can be decreased when combined with Panobinostat.
Dinutuximab Injection	Dinutuximab Injection The risk or severity of adverse effects can be increased when Olanzapine is combined with Dinutuximab.
Haloperidol Injection	Haloperidol Injection The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Haloperidol.
Ivabradine	Ivabradine The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Ivabradine.
Amiloride	Amiloride The risk or severity of adverse effects can be increased when Olanzapine is combined with Amiloride.
Isavuconazonium Injection	Isavuconazonium Injection Olanzapine can cause a decrease in the absorption of Isavuconazonium resulting in a reduced serum concentration and potentially a decrease in efficacy.
Macitentan	Macitentan Olanzapine may increase the hypotensive activities of Macitentan.
Flibanserin	Flibanserin Flibanserin may increase the central nervous system depressant (CNS depressant) activities of Olanzapine.
Rolapitant	Rolapitant The metabolism of Olanzapine can be decreased when combined with Rolapitant.
Brexpiprazole	Brexpiprazole Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Brexpiprazole.
Ziprasidone Injection	Ziprasidone Injection The risk or severity of QTc prolongation can be increased when Ziprasidone is combined with Olanzapine.
Cariprazine	Cariprazine The risk or severity of adverse effects can be increased when Olanzapine is combined with Cariprazine.
Eluxadoline	Eluxadoline The risk or severity of constipation can be increased when Olanzapine is combined with Eluxadoline.
Insulin Degludec (rDNA Origin) Injection	Insulin Degludec (rDNA Origin) Injection The therapeutic efficacy of Insulin degludec can be decreased when used in combination with Olanzapine.
Trabectedin Injection	Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Olanzapine.
Osimertinib	Osimertinib The serum concentration of Olanzapine can be decreased when it is combined with Osimertinib.
Lesinurad	Lesinurad The metabolism of Lesinurad can be decreased when combined with Olanzapine.
Amphotericin B Liposomal Injection	Amphotericin B Liposomal Injection The risk or severity of adverse effects can be increased when Olanzapine is combined with Amphotericin B.
Brivaracetam Injection	Brivaracetam Injection The risk or severity of adverse effects can be increased when Olanzapine is combined with Brivaracetam.
Cobicistat	Cobicistat The metabolism of Olanzapine can be decreased when combined with Cobicistat.
Midodrine	Midodrine The therapeutic efficacy of Midodrine can be decreased when used in combination with Olanzapine.
Selexipag	Selexipag Olanzapine may increase the hypotensive activities of Selexipag.
Pimavanserin	Pimavanserin The risk or severity of adverse effects can be increased when Olanzapine is combined with Pimavanserin.
Obeticholic Acid	Obeticholic Acid The metabolism of Olanzapine can be decreased when combined with Obeticholic acid.
Diphenhydramine Injection	Diphenhydramine Injection The risk or severity of adverse effects can be increased when Olanzapine is combined with Diphenhydramine.
Furosemide Injection	Furosemide Injection The risk or severity of adverse effects can be increased when Olanzapine is combined with Furosemide.
Rucaparib	Rucaparib The metabolism of Rucaparib can be decreased when combined with Olanzapine.
Lixisenatide Injection	Lixisenatide Injection The therapeutic efficacy of Lixisenatide can be decreased when used in combination with Olanzapine.
Ribociclib	Ribociclib The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Ribociclib.
Doxepin (Insomnia)	Doxepin (Insomnia) Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Doxepin.
Plecanatide	Plecanatide The therapeutic efficacy of Plecanatide can be decreased when used in combination with Olanzapine.
Deutetrabenazine	Deutetrabenazine The risk or severity of adverse effects can be increased when Olanzapine is combined with Deutetrabenazine.
Valbenazine	Valbenazine The metabolism of Valbenazine can be decreased when combined with Olanzapine.
Safinamide	Safinamide The metabolism of Olanzapine can be decreased when combined with Safinamide.
Midostaurin	Midostaurin The metabolism of Olanzapine can be decreased when combined with Midostaurin.
Enasidenib	Enasidenib The metabolism of Olanzapine can be decreased when combined with Enasidenib.
Delafloxacin	Delafloxacin The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Delafloxacin.
Letermovir	Letermovir The metabolism of Letermovir can be decreased when combined with Olanzapine.
Semaglutide Injection	Semaglutide Injection The therapeutic efficacy of Semaglutide can be decreased when used in combination with Olanzapine.
Tetrabenazine	Tetrabenazine The risk or severity of adverse effects can be increased when Olanzapine is combined with Tetrabenazine.
Ertugliflozin	Ertugliflozin The therapeutic efficacy of Ertugliflozin can be decreased when used in combination with Olanzapine.
Buprenorphine Injection	Buprenorphine Injection Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Fostamatinib	Fostamatinib The risk or severity of hypotension, dyspepsia, and headache can be increased when Fostamatinib is combined with Olanzapine.
Lofexidine	Lofexidine The therapeutic efficacy of Olanzapine can be increased when used in combination with Lofexidine.
Eliglustat	Eliglustat The risk or severity of QTc prolongation can be increased when Eliglustat is combined with Olanzapine.
Encorafenib	Encorafenib The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Encorafenib.
Binimetinib	Binimetinib The metabolism of Binimetinib can be decreased when combined with Olanzapine.
Ivosidenib	Ivosidenib The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Ivosidenib.
Elagolix	Elagolix The metabolism of Elagolix can be decreased when combined with Olanzapine.
Tafenoquine	Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Olanzapine.
Cannabidiol	Cannabidiol The risk or severity of adverse effects can be increased when Cannabidiol is combined with Olanzapine.
Dacomitinib	Dacomitinib The metabolism of Olanzapine can be decreased when combined with Dacomitinib.
Stiripentol	Stiripentol The risk or severity of adverse effects can be increased when Olanzapine is combined with Stiripentol.
Gilteritinib	Gilteritinib The therapeutic efficacy of Olanzapine can be decreased when used in combination with Gilteritinib.
Glasdegib	Glasdegib The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Glasdegib.
Lorlatinib	Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Olanzapine.
Paclitaxel (with albumin) Injection	Paclitaxel (with albumin) Injection The risk or severity of adverse effects can be increased when Olanzapine is combined with Paclitaxel.
Rifamycin	Rifamycin The metabolism of Olanzapine can be decreased when combined with Rifamycin.
Prucalopride	Prucalopride The therapeutic efficacy of Prucalopride can be decreased when used in combination with Olanzapine.
Magnesium Citrate	Magnesium Citrate The therapeutic efficacy of Magnesium citrate can be decreased when used in combination with Olanzapine.
Emapalumab-lzsg Injection	Emapalumab-lzsg Injection The metabolism of Olanzapine can be increased when combined with Emapalumab.
Siponimod	Siponimod The metabolism of Siponimod can be decreased when combined with Olanzapine.
Acyclovir Ophthalmic	Acyclovir Ophthalmic The metabolism of Acyclovir can be decreased when combined with Olanzapine.
Erdafitinib	Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Olanzapine.
Esomeprazole Injection	Esomeprazole Injection The metabolism of Esomeprazole can be decreased when combined with Olanzapine.
Brexanolone Injection	Brexanolone Injection The risk or severity of adverse effects can be increased when Olanzapine is combined with Brexanolone.
Solriamfetol	Solriamfetol The risk or severity of Tachycardia can be increased when Solriamfetol is combined with Olanzapine.
Triclabendazole	Triclabendazole The metabolism of Triclabendazole can be decreased when combined with Olanzapine.
Entrectinib	Entrectinib The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Entrectinib.
Istradefylline	Istradefylline The metabolism of Istradefylline can be decreased when combined with Olanzapine.
Pitolisant	Pitolisant The therapeutic efficacy of Pitolisant can be decreased when used in combination with Olanzapine.
Fedratinib	Fedratinib The metabolism of Fedratinib can be decreased when combined with Olanzapine.
Lefamulin	Lefamulin Lefamulin may increase the QTc-prolonging activities of Olanzapine.
Phenytoin Injection	Phenytoin Injection The metabolism of Phenytoin can be decreased when combined with Olanzapine.
Fosphenytoin Injection	Fosphenytoin Injection The metabolism of Fosphenytoin can be decreased when combined with Olanzapine.
Voxelotor	Voxelotor The metabolism of Voxelotor can be decreased when combined with Olanzapine.
Avapritinib	Avapritinib The metabolism of Avapritinib can be decreased when combined with Olanzapine.
Lumateperone	Lumateperone The risk or severity of adverse effects can be increased when Olanzapine is combined with Lumateperone.
Lasmiditan	Lasmiditan The risk or severity of serotonin syndrome can be increased when Olanzapine is combined with Lasmiditan.
Cenobamate	Cenobamate The metabolism of Cenobamate can be decreased when combined with Olanzapine.
Selumetinib	Selumetinib The metabolism of Selumetinib can be decreased when combined with Olanzapine.
Selpercatinib	Selpercatinib The serum concentration of Selpercatinib can be decreased when it is combined with Olanzapine.
Capmatinib	Capmatinib The metabolism of Olanzapine can be decreased when combined with Capmatinib.
Lemborexant	Lemborexant Lemborexant may increase the central nervous system depressant (CNS depressant) activities of Olanzapine.
Daratumumab and Hyaluronidase-fihj Injection	Daratumumab and Hyaluronidase-fihj Injection The therapeutic efficacy of Hyaluronidase can be decreased when used in combination with Olanzapine.
Fenfluramine	Fenfluramine The risk or severity of serotonin syndrome can be increased when Olanzapine is combined with Fenfluramine.
Fostemsavir	Fostemsavir The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Fostemsavir.
Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf Injection	Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf Injection The therapeutic efficacy of Hyaluronidase can be decreased when used in combination with Olanzapine.
Octreotide	Octreotide The risk or severity of QTc prolongation can be increased when Octreotide is combined with Olanzapine.
Opicapone	Opicapone The therapeutic efficacy of Opicapone can be decreased when used in combination with Olanzapine.
Satralizumab-mwge Injection	Satralizumab-mwge Injection The serum concentration of Olanzapine can be decreased when it is combined with Satralizumab.
Relugolix	Relugolix The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Relugolix.
Viloxazine	Viloxazine The risk or severity of adverse effects can be increased when Olanzapine is combined with Viloxazine.
Indomethacin	Indomethacin The metabolism of Indomethacin can be decreased when combined with Olanzapine.
Mefenamic Acid	Mefenamic Acid The metabolism of Mefenamic acid can be decreased when combined with Olanzapine.
Naproxen	Naproxen The metabolism of Naproxen can be decreased when combined with Olanzapine.
Trazodone	Trazodone The risk or severity of QTc prolongation can be increased when Trazodone is combined with Olanzapine.
Hydroxyurea	Hydroxyurea The metabolism of Olanzapine can be decreased when combined with Hydroxyurea.
Phenobarbital	Phenobarbital The metabolism of Phenobarbital can be decreased when combined with Olanzapine.
Metaxalone	Metaxalone The risk or severity of adverse effects can be increased when Olanzapine is combined with Metaxalone.
Levorphanol	Levorphanol The risk or severity of adverse effects can be increased when Levorphanol is combined with Olanzapine.
Primidone	Primidone The metabolism of Olanzapine can be increased when combined with Primidone.
Methsuximide	Methsuximide The risk or severity of adverse effects can be increased when Olanzapine is combined with Methsuximide.
Diethylpropion	Diethylpropion Diethylpropion may decrease the sedative and stimulatory activities of Olanzapine.
Chlorpromazine	Chlorpromazine Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Chlorpromazine.
Diazepam	Diazepam The risk or severity of adverse effects can be increased when Diazepam is combined with Olanzapine.
Oxazepam	Oxazepam The risk or severity of adverse effects can be increased when Olanzapine is combined with Oxazepam.
Flurazepam	Flurazepam The risk or severity of adverse effects can be increased when Olanzapine is combined with Flurazepam.
Clorazepate	Clorazepate The risk or severity of adverse effects can be increased when Olanzapine is combined with Clorazepic acid.
Lorazepam	Lorazepam The risk or severity of adverse effects can be increased when Lorazepam is combined with Olanzapine.
Phenoxybenzamine	Phenoxybenzamine Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Phenoxybenzamine.
Carmustine	Carmustine The metabolism of Olanzapine can be decreased when combined with Carmustine.
Amantadine	Amantadine The therapeutic efficacy of Amantadine can be decreased when used in combination with Olanzapine.
Codeine	Codeine The risk or severity of adverse effects can be increased when Codeine is combined with Olanzapine.
Meprobamate	Meprobamate The risk or severity of adverse effects can be increased when Olanzapine is combined with Meprobamate.
Chlordiazepoxide	Chlordiazepoxide The risk or severity of adverse effects can be increased when Olanzapine is combined with Chlordiazepoxide.
Bromocriptine	Bromocriptine Bromocriptine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Olanzapine.
Metaproterenol	Metaproterenol The therapeutic efficacy of Orciprenaline can be decreased when used in combination with Olanzapine.
Tranylcypromine	Tranylcypromine The metabolism of Tranylcypromine can be decreased when combined with Olanzapine.
Phenelzine	Phenelzine The risk or severity of adverse effects can be increased when Olanzapine is combined with Phenelzine.
Procarbazine	Procarbazine The risk or severity of adverse effects can be increased when Olanzapine is combined with Procarbazine.
Ergoloid Mesylates	Ergoloid Mesylates The risk or severity of adverse effects can be increased when Olanzapine is combined with Ergoloid mesylate.
Minocycline	Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Olanzapine.
Prochlorperazine	Prochlorperazine The risk or severity of adverse effects can be increased when Olanzapine is combined with Prochlorperazine.
Thioridazine	Thioridazine Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Thioridazine.
Trifluoperazine	Trifluoperazine Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Trifluoperazine.
Dapsone	Dapsone The metabolism of Dapsone can be decreased when combined with Olanzapine.
Sulfadiazine	Sulfadiazine The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Olanzapine.
Oxycodone	Oxycodone The risk or severity of adverse effects can be increased when Oxycodone is combined with Olanzapine.
Methadone	Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Olanzapine.
Oxybutynin	Oxybutynin Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Oxybutynin.
Benztropine	Benztropine The risk or severity of adverse effects can be increased when Olanzapine is combined with Benzatropine.
Maprotiline	Maprotiline The risk or severity of adverse effects can be increased when Olanzapine is combined with Maprotiline.
Ibuprofen	Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Olanzapine.
Trihexyphenidyl	Trihexyphenidyl The therapeutic efficacy of Trihexyphenidyl can be decreased when used in combination with Olanzapine.
Orphenadrine	Orphenadrine Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Perphenazine	Perphenazine The risk or severity of adverse effects can be increased when Olanzapine is combined with Perphenazine.
Azathioprine	Azathioprine The metabolism of Azathioprine can be decreased when combined with Olanzapine.
Fluphenazine	Fluphenazine The risk or severity of adverse effects can be increased when Olanzapine is combined with Fluphenazine.
Phentermine	Phentermine Phentermine may decrease the sedative and stimulatory activities of Olanzapine.
Methylphenidate	Methylphenidate The therapeutic efficacy of Methylphenidate can be decreased when used in combination with Olanzapine.
Amoxapine	Amoxapine Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Amoxapine.
Doxorubicin	Doxorubicin The metabolism of Olanzapine can be decreased when combined with Doxorubicin.
Mechlorethamine	Mechlorethamine The therapeutic efficacy of Olanzapine can be decreased when used in combination with Mechlorethamine.
Pyridostigmine	Pyridostigmine The therapeutic efficacy of Olanzapine can be decreased when used in combination with Pyridostigmine.
Carbamazepine	Carbamazepine The metabolism of Carbamazepine can be increased when combined with Olanzapine.
Molindone	Molindone The risk or severity of adverse effects can be increased when Olanzapine is combined with Molindone.
Methyldopa	Methyldopa The therapeutic efficacy of Methyldopa can be decreased when used in combination with Olanzapine.
Clonidine	Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Olanzapine.
Prazosin	Prazosin Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Prazosin.
Hydralazine	Hydralazine The risk or severity of adverse effects can be increased when Olanzapine is combined with Hydralazine.
Cimetidine	Cimetidine The metabolism of Olanzapine can be decreased when combined with Cimetidine.
Clonazepam	Clonazepam The risk or severity of adverse effects can be increased when Olanzapine is combined with Clonazepam.
Loperamide	Loperamide The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Loperamide.
Promethazine	Promethazine Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Promethazine.
Griseofulvin	Griseofulvin The metabolism of Olanzapine can be increased when combined with Griseofulvin.
Digoxin	Digoxin The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Digoxin.
Loxapine	Loxapine The risk or severity of adverse effects can be increased when Olanzapine is combined with Loxapine.
Chloroquine	Chloroquine The metabolism of Olanzapine can be decreased when combined with Chloroquine.
Quinine	Quinine The metabolism of Quinine can be decreased when combined with Olanzapine.
Ethosuximide	Ethosuximide The risk or severity of adverse effects can be increased when Olanzapine is combined with Ethosuximide.
Triamterene	Triamterene The metabolism of Triamterene can be decreased when combined with Olanzapine.
Lactulose	Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Olanzapine.
Chlorothiazide	Chlorothiazide The serum concentration of Chlorothiazide can be increased when it is combined with Olanzapine.
Chlorthalidone	Chlorthalidone The serum concentration of Chlorthalidone can be increased when it is combined with Olanzapine.
Metolazone	Metolazone The serum concentration of Metolazone can be increased when it is combined with Olanzapine.
Secobarbital	Secobarbital The risk or severity of adverse effects can be increased when Olanzapine is combined with Secobarbital.
Amitriptyline	Amitriptyline Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Amitriptyline.
Quinidine	Quinidine Quinidine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Olanzapine.
Procainamide	Procainamide The metabolism of Procainamide can be decreased when combined with Olanzapine.
Isoniazid	Isoniazid The metabolism of Olanzapine can be decreased when combined with Isoniazid.
Rifampin	Rifampin The metabolism of Olanzapine can be increased when combined with Rifampicin.
Disopyramide	Disopyramide The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Disopyramide.
Valproic Acid	Valproic Acid The serum concentration of Olanzapine can be decreased when it is combined with Valproic acid.
Tamoxifen	Tamoxifen The metabolism of Tamoxifen can be decreased when combined with Olanzapine.
Butabarbital	Butabarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Olanzapine.
Methimazole	Methimazole The metabolism of Olanzapine can be decreased when combined with Methimazole.
Chlorpropamide	Chlorpropamide The therapeutic efficacy of Chlorpropamide can be decreased when used in combination with Olanzapine.
Glucagon Injection	Glucagon Injection Olanzapine may increase the gastrointestinal motility reducing activities of Glucagon.
Tolbutamide	Tolbutamide The therapeutic efficacy of Tolbutamide can be decreased when used in combination with Olanzapine.
Tolazamide	Tolazamide The therapeutic efficacy of Tolazamide can be decreased when used in combination with Olanzapine.
Dextromethorphan	Dextromethorphan The risk or severity of adverse effects can be increased when Olanzapine is combined with Dextromethorphan.
Cyclobenzaprine	Cyclobenzaprine The risk or severity of CNS depression can be increased when Olanzapine is combined with Cyclobenzaprine.
Niacin	Niacin The metabolism of Olanzapine can be decreased when combined with Niacin.
Baclofen	Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Olanzapine.
Doxylamine	Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Olanzapine.
Cyproheptadine	Cyproheptadine Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Cyproheptadine.
Clemastine	Clemastine The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Clemastine.
Chlorpheniramine	Chlorpheniramine The risk or severity of adverse effects can be increased when Olanzapine is combined with Chlorpheniramine.
Brompheniramine	Brompheniramine The risk or severity of adverse effects can be increased when Olanzapine is combined with Dexbrompheniramine.
Meclizine	Meclizine The risk or severity of adverse effects can be increased when Olanzapine is combined with Meclizine.
Methyclothiazide	Methyclothiazide The serum concentration of Methyclothiazide can be increased when it is combined with Olanzapine.
Hydrochlorothiazide	Hydrochlorothiazide The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Hydrochlorothiazide.
Dantrolene	Dantrolene The risk or severity of adverse effects can be increased when Olanzapine is combined with Dantrolene.
Chlorzoxazone	Chlorzoxazone The risk or severity of adverse effects can be increased when Olanzapine is combined with Chlorzoxazone.
Carisoprodol	Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Olanzapine.
Methocarbamol	Methocarbamol The risk or severity of adverse effects can be increased when Olanzapine is combined with Methocarbamol.
Disulfiram	Disulfiram The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Disulfiram.
Propranolol (Cardiovascular)	Propranolol (Cardiovascular) The serum concentration of Propranolol can be increased when it is combined with Olanzapine.
Minoxidil	Minoxidil The risk or severity of adverse effects can be increased when Olanzapine is combined with Minoxidil.
Pseudoephedrine	Pseudoephedrine Pseudoephedrine may decrease the sedative and stimulatory activities of Olanzapine.
Nortriptyline	Nortriptyline The serum concentration of Nortriptyline can be increased when it is combined with Olanzapine.
Spironolactone	Spironolactone The risk or severity of adverse effects can be increased when Olanzapine is combined with Spironolactone.
Amphotericin B Injection	Amphotericin B Injection The risk or severity of adverse effects can be increased when Olanzapine is combined with Amphotericin B.
Nadolol	Nadolol Nadolol may increase the orthostatic hypotensive activities of Olanzapine.
Butorphanol Injection	Butorphanol Injection The risk or severity of adverse effects can be increased when Butorphanol is combined with Olanzapine.
Nalbuphine Injection	Nalbuphine Injection The risk or severity of adverse effects can be increased when Nalbuphine is combined with Olanzapine.
Oxytocin Injection	Oxytocin Injection The risk or severity of QTc prolongation can be increased when Oxytocin is combined with Olanzapine.
Trimethobenzamide	Trimethobenzamide Trimethobenzamide may increase the central nervous system depressant (CNS depressant) activities of Olanzapine.
Flavoxate	Flavoxate Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Flavoxate.
Papaverine	Papaverine The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Papaverine.
Fluorouracil Injection	Fluorouracil Injection The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Fluorouracil.
Dacarbazine	Dacarbazine The metabolism of Dacarbazine can be decreased when combined with Olanzapine.
Acetazolamide	Acetazolamide The risk or severity of adverse effects can be increased when Olanzapine is combined with Acetazolamide.
Ketoconazole	Ketoconazole Olanzapine can cause a decrease in the absorption of Ketoconazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Pyrantel	Pyrantel The risk or severity of adverse effects can be increased when Olanzapine is combined with Pyrantel.
Thiotepa Injection	Thiotepa Injection The therapeutic efficacy of Olanzapine can be decreased when used in combination with Thiotepa.
Captopril	Captopril The risk or severity of adverse effects can be increased when Olanzapine is combined with Captopril.
Dipyridamole	Dipyridamole The risk or severity of hypotension, dyspepsia, and headache can be increased when Dipyridamole is combined with Olanzapine.
Isoxsuprine	Isoxsuprine The therapeutic efficacy of Isoxsuprine can be decreased when used in combination with Olanzapine.
Vinblastine	Vinblastine The metabolism of Olanzapine can be decreased when combined with Vinblastine.
Ethacrynic Acid	Ethacrynic Acid The risk or severity of adverse effects can be increased when Olanzapine is combined with Etacrynic acid.
Metoprolol	Metoprolol The metabolism of Olanzapine can be decreased when combined with Metoprolol.
Hydroxyzine	Hydroxyzine The risk or severity of QTc prolongation can be increased when Hydroxyzine is combined with Olanzapine.
Thiothixene	Thiothixene The risk or severity of adverse effects can be increased when Olanzapine is combined with Thiothixene.
Aspirin	Aspirin The metabolism of Acetylsalicylic acid can be decreased when combined with Olanzapine.
Alprazolam	Alprazolam Alprazolam may increase the central nervous system depressant (CNS depressant) activities of Olanzapine.
Temazepam	Temazepam The risk or severity of adverse effects can be increased when Temazepam is combined with Olanzapine.
Triazolam	Triazolam The risk or severity of adverse effects can be increased when Olanzapine is combined with Triazolam.
Dicyclomine	Dicyclomine Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine.
Hyoscyamine	Hyoscyamine Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine.
Propantheline	Propantheline Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Propantheline.
Trimethoprim	Trimethoprim The metabolism of Trimethoprim can be decreased when combined with Olanzapine.
Diltiazem	Diltiazem The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Diltiazem.
Nifedipine	Nifedipine The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Nifedipine.
Timolol	Timolol The metabolism of Timolol can be decreased when combined with Olanzapine.
Verapamil	Verapamil Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Verapamil.
Atenolol	Atenolol Atenolol may increase the orthostatic hypotensive activities of Olanzapine.
Pindolol	Pindolol Pindolol may increase the orthostatic hypotensive activities of Olanzapine.
Cisplatin Injection	Cisplatin Injection The therapeutic efficacy of Olanzapine can be decreased when used in combination with Cisplatin.
Piroxicam	Piroxicam The metabolism of Piroxicam can be decreased when combined with Olanzapine.
Bumetanide	Bumetanide The risk or severity of adverse effects can be increased when Olanzapine is combined with Bumetanide.
Streptozocin	Streptozocin The metabolism of Olanzapine can be increased when combined with Streptozocin.
Etoposide	Etoposide The metabolism of Etoposide can be decreased when combined with Olanzapine.
Glyburide	Glyburide The metabolism of Glyburide can be decreased when combined with Olanzapine.
Glipizide	Glipizide The therapeutic efficacy of Glipizide can be decreased when used in combination with Olanzapine.
Indapamide	Indapamide The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Indapamide.
Nafcillin Injection	Nafcillin Injection The metabolism of Olanzapine can be increased when combined with Nafcillin.
Pentoxifylline	Pentoxifylline The metabolism of Pentoxifylline can be decreased when combined with Olanzapine.
Pentamidine Injection	Pentamidine Injection The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Pentamidine.
Labetalol	Labetalol Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Labetalol.
Leuprolide Injection	Leuprolide Injection The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Leuprolide.
Gemfibrozil	Gemfibrozil The metabolism of Olanzapine can be decreased when combined with Gemfibrozil.
Guanabenz	Guanabenz The therapeutic efficacy of Guanabenz can be decreased when used in combination with Olanzapine.
Pimozide	Pimozide The metabolism of Pimozide can be decreased when combined with Olanzapine.
Enalapril	Enalapril The risk or severity of adverse effects can be increased when Olanzapine is combined with Enalapril.
Flurbiprofen	Flurbiprofen The metabolism of Flurbiprofen can be decreased when combined with Olanzapine.
Amiodarone	Amiodarone The metabolism of Olanzapine can be decreased when combined with Amiodarone.
Buspirone	Buspirone The risk or severity of serotonin syndrome can be increased when Olanzapine is combined with Buspirone.
Lovastatin	Lovastatin The metabolism of Olanzapine can be decreased when combined with Lovastatin.
Ciprofloxacin	Ciprofloxacin The metabolism of Olanzapine can be decreased when combined with Ciprofloxacin.
Mesalamine	Mesalamine The therapeutic efficacy of Mesalazine can be decreased when used in combination with Olanzapine.
Diclofenac	Diclofenac The metabolism of Diclofenac can be decreased when combined with Olanzapine.
Nimodipine	Nimodipine The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Nimodipine.
Interferon Alfa-2b Injection	Interferon Alfa-2b Injection The metabolism of Olanzapine can be decreased when combined with Interferon alfa-2b.
Clozapine	Clozapine Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Clozapine.
Estazolam	Estazolam The risk or severity of adverse effects can be increased when Olanzapine is combined with Estazolam.
Idarubicin	Idarubicin The metabolism of Idarubicin can be decreased when combined with Olanzapine.
Ofloxacin	Ofloxacin The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Ofloxacin.
Clarithromycin	Clarithromycin The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Clarithromycin.
Benazepril	Benazepril The risk or severity of adverse effects can be increased when Olanzapine is combined with Benazepril.
Etodolac	Etodolac The metabolism of Etodolac can be decreased when combined with Olanzapine.
Felodipine	Felodipine The metabolism of Olanzapine can be decreased when combined with Felodipine.
Fosinopril	Fosinopril The risk or severity of adverse effects can be increased when Olanzapine is combined with Fosinopril.
Nabumetone	Nabumetone The metabolism of Nabumetone can be decreased when combined with Olanzapine.
Quinapril	Quinapril The risk or severity of adverse effects can be increased when Olanzapine is combined with Quinapril.
Ramipril	Ramipril The risk or severity of adverse effects can be increased when Ramipril is combined with Olanzapine.
Simvastatin	Simvastatin The metabolism of Simvastatin can be decreased when combined with Olanzapine.
Amlodipine	Amlodipine The risk or severity of hypotension can be increased when Amlodipine is combined with Olanzapine.
Teniposide Injection	Teniposide Injection The metabolism of Teniposide can be decreased when combined with Olanzapine.
Itraconazole	Itraconazole Olanzapine can cause a decrease in the absorption of Itraconazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Lisinopril	Lisinopril The risk or severity of adverse effects can be increased when Olanzapine is combined with Lisinopril.
Sotalol	Sotalol The metabolism of Sotalol can be decreased when combined with Olanzapine.
Bisoprolol	Bisoprolol Olanzapine may increase the orthostatic hypotensive activities of Bisoprolol.
Zolpidem	Zolpidem Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Doxazosin	Doxazosin Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Doxazosin.
Terazosin	Terazosin Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Terazosin.
Isradipine	Isradipine The risk or severity of QTc prolongation can be increased when Isradipine is combined with Olanzapine.
Omeprazole	Omeprazole The metabolism of Omeprazole can be increased when combined with Olanzapine.
Cisapride	Cisapride The metabolism of Olanzapine can be decreased when combined with Cisapride.
Gabapentin	Gabapentin The risk or severity of adverse effects can be increased when Olanzapine is combined with Gabapentin.
Fluvastatin	Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Olanzapine.
Venlafaxine	Venlafaxine The metabolism of Olanzapine can be decreased when combined with Venlafaxine.
Nizatidine	Nizatidine The therapeutic efficacy of Olanzapine can be decreased when used in combination with Nizatidine.
Fluvoxamine	Fluvoxamine The metabolism of Olanzapine can be decreased when combined with Fluvoxamine.
Nefazodone	Nefazodone Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Nefazodone.
Lamotrigine	Lamotrigine The risk or severity of adverse effects can be increased when Olanzapine is combined with Lamotrigine.
Losartan	Losartan The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Losartan.
Tramadol	Tramadol The risk or severity of serotonin syndrome can be increased when Tramadol is combined with Olanzapine.
Vinorelbine Injection	Vinorelbine Injection The metabolism of Olanzapine can be decreased when combined with Vinorelbine.
Moexipril	Moexipril The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Moexipril.
Lansoprazole	Lansoprazole The metabolism of Lansoprazole can be decreased when combined with Olanzapine.
Ifosfamide Injection	Ifosfamide Injection The metabolism of Ifosfamide can be decreased when combined with Olanzapine.
Nicardipine	Nicardipine Nicardipine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Olanzapine.
Bupropion	Bupropion The metabolism of Bupropion can be decreased when combined with Olanzapine.
Ticlopidine	Ticlopidine The metabolism of Olanzapine can be decreased when combined with Ticlopidine.
Saquinavir	Saquinavir Saquinavir can cause an increase in the absorption of Olanzapine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Metformin	Metformin The therapeutic efficacy of Metformin can be decreased when used in combination with Olanzapine.
Nisoldipine	Nisoldipine The risk or severity of hypotension can be increased when Olanzapine is combined with Nisoldipine.
Riluzole	Riluzole The risk or severity of adverse effects can be increased when Olanzapine is combined with Riluzole.
Amifostine Injection	Amifostine Injection The risk or severity of adverse effects can be increased when Olanzapine is combined with Amifostine.
Acarbose	Acarbose The therapeutic efficacy of Acarbose can be decreased when used in combination with Olanzapine.
Glimepiride	Glimepiride The therapeutic efficacy of Glimepiride can be decreased when used in combination with Olanzapine.
Indinavir	Indinavir Olanzapine can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ritonavir	Ritonavir The metabolism of Olanzapine can be decreased when combined with Ritonavir.
Clomipramine	Clomipramine The metabolism of Olanzapine can be decreased when combined with Clomipramine.
Zafirlukast	Zafirlukast The metabolism of Olanzapine can be decreased when combined with Zafirlukast.
Mirtazapine	Mirtazapine Olanzapine may increase the serotonergic activities of Mirtazapine.
Trandolapril	Trandolapril The risk or severity of adverse effects can be increased when Olanzapine is combined with Trandolapril.
Topiramate	Topiramate The risk or severity of hyperthermia and oligohydrosis can be increased when Olanzapine is combined with Topiramate.
Zileuton	Zileuton The metabolism of Zileuton can be decreased when combined with Olanzapine.
Valsartan	Valsartan The risk or severity of adverse effects can be increased when Olanzapine is combined with Valsartan.
Insulin Lispro Injection	Insulin Lispro Injection The therapeutic efficacy of Insulin lispro can be decreased when used in combination with Olanzapine.
Pramipexole	Pramipexole The therapeutic efficacy of Pramipexole can be decreased when used in combination with Olanzapine.
Donepezil	Donepezil The therapeutic efficacy of Olanzapine can be decreased when used in combination with Donepezil.
Nelfinavir	Nelfinavir Olanzapine can cause a decrease in the absorption of Nelfinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Azithromycin	Azithromycin The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Azithromycin.
Loratadine	Loratadine Olanzapine may increase the anticholinergic activities of Loratadine.
Carvedilol	Carvedilol Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Carvedilol.
Flutamide	Flutamide The metabolism of Flutamide can be decreased when combined with Olanzapine.
Selegiline	Selegiline The risk or severity of adverse effects can be increased when Olanzapine is combined with Selegiline.
Bicalutamide	Bicalutamide The metabolism of Olanzapine can be decreased when combined with Bicalutamide.
Sertraline	Sertraline The risk or severity of adverse effects can be increased when Olanzapine is combined with Sertraline.
Propafenone	Propafenone The metabolism of Olanzapine can be decreased when combined with Propafenone.
Irbesartan	Irbesartan The risk or severity of adverse effects can be increased when Olanzapine is combined with Irbesartan.
Tamsulosin	Tamsulosin Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Tamsulosin.
Ropinirole	Ropinirole The therapeutic efficacy of Ropinirole can be decreased when used in combination with Olanzapine.
Quetiapine	Quetiapine Olanzapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Quetiapine.
Cefpodoxime	Cefpodoxime Olanzapine can cause a decrease in the absorption of Cefpodoxime resulting in a reduced serum concentration and potentially a decrease in efficacy.
Cetirizine	Cetirizine The risk or severity of adverse effects can be increased when Olanzapine is combined with Cetirizine.
Paroxetine	Paroxetine The metabolism of Paroxetine can be decreased when combined with Olanzapine.
Tolcapone	Tolcapone The therapeutic efficacy of Tolcapone can be decreased when used in combination with Olanzapine.
Citalopram	Citalopram The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Citalopram.
Capecitabine	Capecitabine The metabolism of Capecitabine can be decreased when combined with Olanzapine.
Efavirenz	Efavirenz The risk or severity of QTc prolongation can be increased when Olanzapine is combined with Efavirenz.
Sildenafil	Sildenafil The risk or severity of hypotension, dyspepsia, and headache can be increased when Olanzapine is combined with Sildenafil.
Pioglitazone	Pioglitazone The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Olanzapine.
Celecoxib	Celecoxib The metabolism of Olanzapine can be decreased when combined with Celecoxib.
Rosiglitazone	Rosiglitazone The therapeutic efficacy of Rosiglitazone can be decreased when used in combination with Olanzapine.
Tolterodine	Tolterodine Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine.
Thalidomide	Thalidomide Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Nateglinide	Nateglinide The therapeutic efficacy of Nateglinide can be decreased when used in combination with Olanzapine.
Galantamine	Galantamine The risk or severity of QTc prolongation can be increased when Galantamine is combined with Olanzapine.
Levetiracetam	Levetiracetam The risk or severity of adverse effects can be increased when Olanzapine is combined with Levetiracetam.
Rabeprazole	Rabeprazole The metabolism of Rabeprazole can be decreased when combined with Olanzapine.
Terbinafine	Terbinafine The metabolism of Terbinafine can be decreased when combined with Olanzapine.