Cariprazine

Generic name: Pronounced as (kar ip ra zeen)
Brand names
  • Vraylar®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 07/15/2019

Important warning for older adults with dementia:

Studies have shown that older adults with dementia (a brain disorder that affects the ability to remember, think clearly, communicate, and perform daily activities and that may cause changes in mood and personality) who take antipsychotics (medications for mental illness) such as cariprazine have an increased chance of death during treatment. Older adults with dementia may also have a greater chance of having a stroke or mini-stroke during treatment.

Cariprazine is not approved by the Food and Drug Administration (FDA) for the treatment of behavior disorders in older adults with dementia. Talk to the doctor who prescribed this medication if you, a family member, or someone you care for has dementia and is being treated with cariprazine. For more information visit the FDA website: http://www.fda.gov/Drugs.

Important warning for people with episodes of depression:

A small number of children, teenagers, and young adults (up to 24 years of age) who took antidepressants ('mood elevators') such as cariprazine during clinical studies became suicidal (thinking about harming or killing oneself or planning or trying to do so). Children, teenagers, and young adults who take antidepressants to treat depression or other mental illnesses may be more likely to become suicidal than children, teenagers, and young adults who do not take antidepressants to treat these conditions. However, there are also risks when depression is not treated in children and teenagers. Talk to your child's doctor about these risks and whether your child should take an antidepressant. Cariprazine has not been studied in children younger than 18 years of age.

You should know that your mental health may change in unexpected ways when you take cariprazine or other antidepressants even if you are an adult over 24 years of age. You may become suicidal, especially at the beginning of your treatment and any time that your dose is increased or decreased. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: new or worsening depression; thinking about harming or killing yourself, or planning or trying to do so; extreme worry; agitation; panic attacks; difficulty falling asleep or staying asleep; aggressive behavior; irritability; acting without thinking; severe restlessness; and frenzied abnormal excitement. Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor if you are unable to seek treatment on your own.

Your healthcare provider will want to see you often while you are taking cariprazine, especially at the beginning of your treatment. Be sure to keep all appointments for office visits with your doctor.

The doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with cariprazine. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also obtain the Medication Guide from the FDA website: http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm.

No matter what your age, before you take an antidepressant, you or your caregiver should talk to your doctor about the risks and benefits of treating your condition with an antidepressant or with other treatments. You should also talk about the risks and benefits of not treating your condition. You should know that having depression or another mental illness greatly increases the risk that you will become suicidal. This risk is higher if you or anyone in your family has or has ever had bipolar disorder (mood that changes from depressed to abnormally excited) or mania (frenzied, abnormally excited mood) or has thought about or attempted suicide. Talk to your doctor about your condition, symptoms, and personal and family medical history. You and your doctor will decide what type of treatment is right for you.

Talk to your doctor about the risks of taking cariprazine.

Cariprazine is used to treat schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). Cariprazine is also used to treat episodes of depression in people with bipolar I disorder (manic depressive disorder; a disease that causes episodes of mania, episodes of depression and other abnormal moods). It is also used as a short term treatment for episodes of mania or mixed episodes (symptoms of mania and depression that happen together) in people with bipolar I disorder. Cariprazine is in a class of medications called atypical antipsychotics. It works by changing the activity of certain natural substances in the brain.

Cariprazine comes as a capsule to take by mouth. It is usually taken once a day with or without food. Take cariprazine at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take cariprazine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor will probably start you on a low dose of cariprazine and gradually increase your dose depending on how well the medication works for you, and the side effects you experience.

Cariprazine may help control your symptoms but will not cure your condition. It may take several weeks or longer before you feel the full benefit of cariprazine. Continue to take cariprazine even if you feel well. Do not stop taking cariprazine without talking to your doctor. Talk to your doctor if you do not feel like you are getting better during your treatment with cariprazine.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking cariprazine,

  • tell your doctor and pharmacist if you are allergic to cariprazine, any other medications, or any of the ingredients in cariprazine capsules. Ask your pharmacist for a list of the ingredients.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: anticholinergics such as atropine (Atropen, Duodote, Enlon-Plus), benztropine (Cogentin), dicyclomine (Bentyl), glycopyrrolate (Robinul), hyoscyamine, propantheline (Pro-Banthine), and scopolamine (Transderm Scop); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); itraconazole (Onmel, Sporanox); ketoconazole; medications for blood pressure; and rifampin (Rifadin, Rimactane, in Rifamate, Rifater). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with cariprazine, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor what herbal products you are taking, especially St. John's wort.

  • tell your doctor if you have a low number of white blood cells, or if you have ever developed a low number of white blood cells as a side effect of a medication that you took. Tell your doctor if you have or have ever had seizures; a stroke; a ministroke; a heart attack; heart failure; irregular heartbeat;; trouble keeping your balance; difficulty swallowing;or heart, liver, or kidney disease. Also tell your doctor if you have severe vomiting, diarrhea or signs of dehydration now, or if you develop these symptoms at any time during your treatment.

  • tell your doctor if you are pregnant, especially if you are in the last few months of your pregnancy, or if you plan to become pregnant or are breastfeeding. If you become pregnant while taking cariprazine, call your doctor. Cariprazine may cause problems in newborns following delivery if it is taken during the last months of pregnancy.

  • you should know that cariprazine may make you drowsy, and may affect your ability to think clearly, make decisions, and react quickly. Do not drive a car or operate machinery during your treatment with cariprazine until you know how this medication affects you.

  • you should know that you may experience hyperglycemia (increases in your blood sugar) while you are receiving this medication, even if you do not already have diabetes. If you have schizophrenia, you are more likely to develop diabetes than people who do not have schizophrenia and receiving cariprazine or similar medications may increase this risk. Tell your doctor immediately if you have any of the following symptoms during your treatment: extreme thirst, frequent urination, extreme hunger, blurred vision, or weakness. It is very important to call your doctor as soon as you have any of these symptoms, because high blood sugar can cause a serious condition called ketoacidosis. Ketoacidosis may become life-threatening if it is not treated at an early stage. Symptoms of ketoacidosis include: dry mouth, nausea and vomiting, shortness of breath, breath that smells fruity, and decreased consciousness.

  • you should know that cariprazine may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common when you first start taking cariprazine. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.

  • you should know that cariprazine may make it harder for your body to cool down when it gets very hot. Tell your doctor if you plan to do vigorous exercise or be exposed to extreme heat. Be sure to drink plenty of water and call your doctor if you experience any of the following symptoms: feeling very hot, sweating heavily, not sweating even though it is hot, dry mouth, excessive thirst, or decreased urination.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Cariprazine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • extreme tiredness

    • restlessness

    • anxiety

    • agitation

    • difficulty falling asleep or staying asleep

    • dizziness, feeling unsteady, or having trouble keeping your balance

    • increased appetite

    • weight gain

    • constipation

    • indigestion

    • nausea

    • increased saliva or drooling

    • blurred vision

  • Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING or SPECIAL PRECAUTIONS section, call your doctor immediately or get emergency medical treatment:

    • seizures

    • unusual movements of your body or face that you cannot control

    • slow movements or shuffling walk

    • loss of ability to move

    • falling

    • fever, sweating, confusion, fast breathing, fast or irregular heartbeat, and severe muscle stiffness

    • muscle weakness or aching

    • blank facial expression

    • difficulty swallowing or breathing

    • tightness in the throat

    • tongue that sticks out of the mouth

    • rash

    • itching

    • hives

    • swelling of the face, throat, tongue, lips, or eyes

    • dark or cola-colored urine

    • swelling in legs and feet

    • decreased urination

  • Cariprazine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include the following:

  • sedation

  • feeling lightheaded, dizzy or faint when standing up from a sitting or lying down position

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to cariprazine.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Delavirdine Delavirdine The metabolism of Cariprazine can be decreased when combined with Delavirdine.
Nevirapine Nevirapine The metabolism of Cariprazine can be decreased when combined with Nevirapine.
Dolasetron Dolasetron The risk or severity of adverse effects can be increased when Dolasetron is combined with Cariprazine.
Candesartan Candesartan Cariprazine may decrease the antihypertensive activities of Candesartan.
Cilostazol Cilostazol The metabolism of Cariprazine can be decreased when combined with Cilostazol.
Diphenoxylate Diphenoxylate The risk or severity of adverse effects can be increased when Diphenoxylate is combined with Cariprazine.
Guanfacine Guanfacine The risk or severity of adverse effects can be increased when Guanfacine is combined with Cariprazine.
Methylergonovine Methylergonovine Methylergometrine may increase the vasoconstricting activities of Cariprazine.
Naratriptan Naratriptan The risk or severity of adverse effects can be increased when Naratriptan is combined with Cariprazine.
Olsalazine Olsalazine The risk or severity of hypertension can be increased when Olsalazine is combined with Cariprazine.
Paregoric Paregoric The risk or severity of adverse effects can be increased when Morphine is combined with Cariprazine.
Penbutolol Penbutolol The metabolism of Cariprazine can be decreased when combined with Acebutolol.
Pentazocine Pentazocine The risk or severity of adverse effects can be increased when Pentazocine is combined with Cariprazine.
Ranitidine Ranitidine The metabolism of Cariprazine can be decreased when combined with Ranitidine.
Reserpine Reserpine The risk or severity of adverse effects can be increased when Reserpine is combined with Cariprazine.
Rizatriptan Rizatriptan The risk or severity of adverse effects can be increased when Rizatriptan is combined with Cariprazine.
Sumatriptan Sumatriptan The risk or severity of adverse effects can be increased when Sumatriptan is combined with Cariprazine.
Tizanidine Tizanidine The risk or severity of adverse effects can be increased when Tizanidine is combined with Cariprazine.
Zolmitriptan Zolmitriptan The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Cariprazine.
Hydromorphone Injection Hydromorphone Injection The risk or severity of adverse effects can be increased when Hydromorphone is combined with Cariprazine.
Meperidine Injection Meperidine Injection The risk or severity of adverse effects can be increased when Meperidine is combined with Cariprazine.
Metoclopramide Injection Metoclopramide Injection The risk or severity of adverse effects can be increased when Metoclopramide is combined with Cariprazine.
Morphine Injection Morphine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Cariprazine.
Altretamine Altretamine Amphetamine may decrease the sedative and stimulatory activities of Cariprazine.
Cyclosporine Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Cariprazine.
Ondansetron Ondansetron The risk or severity of adverse effects can be increased when Ondansetron is combined with Cariprazine.
Granisetron Granisetron The risk or severity of adverse effects can be increased when Granisetron is combined with Cariprazine.
Torsemide Torsemide Cariprazine may decrease the antihypertensive activities of Torasemide.
Olanzapine Olanzapine The risk or severity of adverse effects can be increased when Olanzapine is combined with Cariprazine.
Alosetron Alosetron The risk or severity of adverse effects can be increased when Alosetron is combined with Cariprazine.
Entacapone Entacapone The therapeutic efficacy of Entacapone can be decreased when used in combination with Cariprazine.
Eprosartan Eprosartan Cariprazine may decrease the antihypertensive activities of Eprosartan.
Hydroxychloroquine Hydroxychloroquine The metabolism of Cariprazine can be decreased when combined with Hydroxychloroquine.
Meloxicam Meloxicam The risk or severity of hypertension can be increased when Meloxicam is combined with Cariprazine.
Oxcarbazepine Oxcarbazepine The risk or severity of adverse effects can be increased when Oxcarbazepine is combined with Cariprazine.
Telmisartan Telmisartan Cariprazine may decrease the antihypertensive activities of Telmisartan.
Zaleplon Zaleplon The risk or severity of adverse effects can be increased when Zaleplon is combined with Cariprazine.
Anakinra Anakinra The metabolism of Cariprazine can be increased when combined with Anakinra.
Desloratadine Desloratadine The risk or severity of adverse effects can be increased when Desloratadine is combined with Cariprazine.
Linezolid Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Cariprazine.
Trimipramine Trimipramine The metabolism of Cariprazine can be decreased when combined with Trimipramine.
Etanercept Injection Etanercept Injection The metabolism of Cariprazine can be increased when combined with Etanercept.
Glycopyrrolate Glycopyrrolate Cariprazine may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium.
Perindopril Perindopril Cariprazine may decrease the antihypertensive activities of Perindopril.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Cariprazine.
Dutasteride Dutasteride The risk or severity of hypertension can be increased when Dutasteride is combined with Cariprazine.
Epinephrine Injection Epinephrine Injection The risk or severity of hypertension can be increased when Epinephrine is combined with Cariprazine.
Eplerenone Eplerenone Cariprazine may decrease the antihypertensive activities of Eplerenone.
Escitalopram Escitalopram The risk or severity of serotonin syndrome can be increased when Escitalopram is combined with Cariprazine.
Olmesartan Olmesartan Cariprazine may decrease the antihypertensive activities of Olmesartan.
Zonisamide Zonisamide The risk or severity of adverse effects can be increased when Zonisamide is combined with Cariprazine.
Adalimumab Injection Adalimumab Injection The metabolism of Cariprazine can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The risk or severity of adverse effects can be increased when Aripiprazole is combined with Cariprazine.
Atomoxetine Atomoxetine The risk or severity of adverse effects can be increased when Atomoxetine is combined with Cariprazine.
Dexmethylphenidate Dexmethylphenidate The risk or severity of adverse effects can be increased when Cariprazine is combined with Dexmethylphenidate.
Almotriptan Almotriptan The risk or severity of adverse effects can be increased when Almotriptan is combined with Cariprazine.
Eletriptan Eletriptan The risk or severity of adverse effects can be increased when Eletriptan is combined with Cariprazine.
Mefloquine Mefloquine The metabolism of Cariprazine can be decreased when combined with Mefloquine.
Memantine Memantine The therapeutic efficacy of Memantine can be decreased when used in combination with Cariprazine.
Tegaserod Tegaserod The metabolism of Cariprazine can be decreased when combined with Tegaserod.
Tadalafil Tadalafil Cariprazine may decrease the antihypertensive activities of Tadalafil.
Frovatriptan Frovatriptan The risk or severity of adverse effects can be increased when Frovatriptan is combined with Cariprazine.
Progesterone Progesterone The metabolism of Cariprazine can be decreased when combined with Progesterone.
Apomorphine Injection Apomorphine Injection The therapeutic efficacy of Apomorphine can be decreased when used in combination with Cariprazine.
Infliximab Injection Infliximab Injection The metabolism of Cariprazine can be increased when combined with Infliximab.
Protriptyline Protriptyline The risk or severity of adverse effects can be increased when Protriptyline is combined with Cariprazine.
Duloxetine Duloxetine The metabolism of Cariprazine can be decreased when combined with Duloxetine.
Trospium Trospium Cariprazine may increase the central nervous system depressant (CNS depressant) activities of Trospium.
Bosentan Bosentan Cariprazine may decrease the antihypertensive activities of Bosentan.
Cinacalcet Cinacalcet The metabolism of Cariprazine can be decreased when combined with Cinacalcet.
Erlotinib Erlotinib The metabolism of Cariprazine can be decreased when combined with Erlotinib.
Eszopiclone Eszopiclone The risk or severity of CNS depression can be increased when Cariprazine is combined with Eszopiclone.
Solifenacin Solifenacin Cariprazine may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
Dextroamphetamine Dextroamphetamine Amphetamine may decrease the sedative and stimulatory activities of Cariprazine.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The metabolism of Cariprazine can be decreased when combined with Peginterferon alfa-2b.
Sodium Oxybate Sodium Oxybate Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Cariprazine.
Isocarboxazid Isocarboxazid The metabolism of Cariprazine can be decreased when combined with Isocarboxazid.
Ramelteon Ramelteon The risk or severity of adverse effects can be increased when Ramelteon is combined with Cariprazine.
Darifenacin Darifenacin The metabolism of Darifenacin can be decreased when combined with Cariprazine.
Fentanyl Fentanyl The risk or severity of adverse effects can be increased when Fentanyl is combined with Cariprazine.
Pregabalin Pregabalin The therapeutic efficacy of Cariprazine can be increased when used in combination with Pregabalin.
Phenylephrine Phenylephrine The risk or severity of hypertension can be increased when Phenylephrine is combined with Cariprazine.
Tipranavir Tipranavir The metabolism of Tipranavir can be decreased when combined with Cariprazine.
Felbamate Felbamate The risk or severity of adverse effects can be increased when Felbamate is combined with Cariprazine.
Ranolazine Ranolazine The serum concentration of Cariprazine can be increased when it is combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Cariprazine can be increased when combined with Abatacept.
Rasagiline Rasagiline The metabolism of Cariprazine can be decreased when combined with Rasagiline.
Imatinib Imatinib The metabolism of Cariprazine can be decreased when combined with Imatinib.
Gefitinib Gefitinib The metabolism of Cariprazine can be decreased when combined with Gefitinib.
Albuterol Albuterol The risk or severity of hypertension can be increased when Salbutamol is combined with Cariprazine.
Paliperidone Paliperidone The risk or severity of adverse effects can be increased when Paliperidone is combined with Cariprazine.
Bortezomib Bortezomib The metabolism of Cariprazine can be decreased when combined with Bortezomib.
Primaquine Primaquine The metabolism of Cariprazine can be decreased when combined with Primaquine.
Aliskiren Aliskiren Cariprazine may decrease the antihypertensive activities of Aliskiren.
Bismuth Subsalicylate Bismuth Subsalicylate Bismuth subsalicylate may increase the neurotoxic activities of Cariprazine.
Dimenhydrinate Dimenhydrinate The risk or severity of adverse effects can be increased when Dimenhydrinate is combined with Cariprazine.
Lisdexamfetamine Lisdexamfetamine Lisdexamfetamine may decrease the sedative and stimulatory activities of Cariprazine.
Nabilone Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Cariprazine.
Sorafenib Sorafenib The metabolism of Cariprazine can be decreased when combined with Sorafenib.
Dronabinol Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Cariprazine.
Levocetirizine Levocetirizine The risk or severity of adverse effects can be increased when Cariprazine is combined with Levocetirizine.
Mexiletine Mexiletine The metabolism of Cariprazine can be decreased when combined with Mexiletine.
Temsirolimus Temsirolimus The metabolism of Cariprazine can be decreased when combined with Temsirolimus.
Nilotinib Nilotinib The metabolism of Cariprazine can be decreased when combined with Nilotinib.
Desmopressin Desmopressin The risk or severity of hypertension can be increased when Desmopressin is combined with Cariprazine.
OnabotulinumtoxinA Injection OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Cariprazine.
RimabotulinumtoxinB Injection RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Botulinum Toxin Type B is combined with Cariprazine.
Desvenlafaxine Desvenlafaxine The risk or severity of adverse effects can be increased when Cariprazine is combined with Desvenlafaxine.
Cevimeline Cevimeline The metabolism of Cariprazine can be decreased when combined with Cevimeline.
Nebivolol Nebivolol Cariprazine may decrease the antihypertensive activities of Nebivolol.
Flecainide Flecainide The metabolism of Flecainide can be decreased when combined with Cariprazine.
Certolizumab Injection Certolizumab Injection The metabolism of Cariprazine can be increased when combined with Certolizumab pegol.
Rufinamide Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Cariprazine.
Midazolam Midazolam The risk or severity of adverse effects can be increased when Midazolam is combined with Cariprazine.
Naltrexone Injection Naltrexone Injection The risk or severity of serotonin syndrome can be increased when Naltrexone is combined with Cariprazine.
Milnacipran Milnacipran The risk or severity of adverse effects can be increased when Milnacipran is combined with Cariprazine.
Fesoterodine Fesoterodine Cariprazine may increase the central nervous system depressant (CNS depressant) activities of Fesoterodine.
Betaxolol Betaxolol The metabolism of Cariprazine can be decreased when combined with Betaxolol.
Iloperidone Iloperidone The risk or severity of adverse effects can be increased when Iloperidone is combined with Cariprazine.
Lacosamide Lacosamide The risk or severity of adverse effects can be increased when Cariprazine is combined with Lacosamide.
Everolimus Everolimus The metabolism of Cariprazine can be decreased when combined with Everolimus.
Dronedarone Dronedarone The metabolism of Dronedarone can be decreased when combined with Cariprazine.
AbobotulinumtoxinA Injection AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Cariprazine.
Palonosetron Injection Palonosetron Injection The risk or severity of adverse effects can be increased when Palonosetron is combined with Cariprazine.
Tapentadol Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Cariprazine.
Golimumab Injection Golimumab Injection The metabolism of Cariprazine can be increased when combined with Golimumab.
Pazopanib Pazopanib The metabolism of Cariprazine can be decreased when combined with Pazopanib.
Asenapine Asenapine The risk or severity of adverse effects can be increased when Cariprazine is combined with Asenapine.
Vigabatrin Vigabatrin The risk or severity of adverse effects can be increased when Vigabatrin is combined with Cariprazine.
Oxymorphone Oxymorphone The risk or severity of adverse effects can be increased when Oxymorphone is combined with Cariprazine.
Tocilizumab Injection Tocilizumab Injection The metabolism of Cariprazine can be increased when combined with Tocilizumab.
IncobotulinumtoxinA Injection IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Cariprazine.
Lurasidone Lurasidone The risk or severity of adverse effects can be increased when Cariprazine is combined with Lurasidone.
Acetaminophen Injection Acetaminophen Injection The metabolism of Cariprazine can be decreased when combined with Acetaminophen.
Vilazodone Vilazodone The metabolism of Vilazodone can be decreased when combined with Cariprazine.
Terbutaline Injection Terbutaline Injection The risk or severity of hypertension can be increased when Terbutaline is combined with Cariprazine.
Rilpivirine Rilpivirine The metabolism of Cariprazine can be decreased when combined with Rilpivirine.
Cyclophosphamide Injection Cyclophosphamide Injection Cyclophosphamide may increase the neurotoxic activities of Cariprazine.
Abiraterone Abiraterone The metabolism of Cariprazine can be decreased when combined with Abiraterone.
Clobazam Clobazam The metabolism of Cariprazine can be decreased when combined with Clobazam.
Vemurafenib Vemurafenib The metabolism of Cariprazine can be decreased when combined with Vemurafenib.
Cabergoline Cabergoline Cabergoline may increase the vasoconstricting activities of Cariprazine.
Ambrisentan Ambrisentan Cariprazine may decrease the antihypertensive activities of Ambrisentan.
Ezogabine Ezogabine The risk or severity of adverse effects can be increased when Tiagabine is combined with Cariprazine.
Mirabegron Mirabegron The metabolism of Mirabegron can be decreased when combined with Cariprazine.
Alogliptin Alogliptin The metabolism of Alogliptin can be decreased when combined with Cariprazine.
Ponatinib Ponatinib The metabolism of Ponatinib can be decreased when combined with Cariprazine.
Pomalidomide Pomalidomide The risk or severity of adverse effects can be increased when Cariprazine is combined with Pomalidomide.
Ospemifene Ospemifene The metabolism of Cariprazine can be decreased when combined with Ospemifene.
Levomilnacipran Levomilnacipran The risk or severity of adverse effects can be increased when Cariprazine is combined with Levomilnacipran.
Vortioxetine Vortioxetine The risk or severity of adverse effects can be increased when Cariprazine is combined with Vortioxetine.
Perampanel Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Cariprazine.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Cariprazine.
Ketorolac Injection Ketorolac Injection The risk or severity of hypertension can be increased when Ketorolac is combined with Cariprazine.
Dapagliflozin Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Cariprazine.
Apremilast Apremilast The metabolism of Cariprazine can be increased when combined with Apremilast.
Droxidopa Droxidopa Cariprazine may increase the hypertensive activities of Droxidopa.
Siltuximab Injection Siltuximab Injection The metabolism of Cariprazine can be increased when combined with Siltuximab.
Eslicarbazepine Eslicarbazepine The risk or severity of adverse effects can be increased when Cariprazine is combined with Eslicarbazepine.
Oritavancin Injection Oritavancin Injection The metabolism of Cariprazine can be decreased when combined with Oritavancin.
Hydrocodone Hydrocodone Hydrocodone may increase the central nervous system depressant (CNS depressant) activities of Cariprazine.
Suvorexant Suvorexant Cariprazine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Methamphetamine Methamphetamine Metamfetamine may decrease the sedative and stimulatory activities of Cariprazine.
Tasimelteon Tasimelteon The risk or severity of adverse effects can be increased when Cariprazine is combined with Tasimelteon.
Riociguat Riociguat Cariprazine may decrease the antihypertensive activities of Riociguat.
Secukinumab Injection Secukinumab Injection The metabolism of Cariprazine can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The risk or severity of adverse effects can be increased when Risperidone is combined with Cariprazine.
Lenvatinib Lenvatinib The metabolism of Cariprazine can be decreased when combined with Lenvatinib.
Naloxegol Naloxegol The metabolism of Cariprazine can be decreased when combined with Naloxegol.
Panobinostat Panobinostat The metabolism of Cariprazine can be decreased when combined with Panobinostat.
Haloperidol Injection Haloperidol Injection The risk or severity of CNS depression can be increased when Haloperidol is combined with Cariprazine.
Macitentan Macitentan Cariprazine may decrease the antihypertensive activities of Macitentan.
Flibanserin Flibanserin The risk or severity of adverse effects can be increased when Flibanserin is combined with Cariprazine.
Rolapitant Rolapitant The metabolism of Cariprazine can be decreased when combined with Rolapitant.
Brexpiprazole Brexpiprazole The risk or severity of adverse effects can be increased when Cariprazine is combined with Brexpiprazole.
Ziprasidone Injection Ziprasidone Injection The risk or severity of adverse effects can be increased when Ziprasidone is combined with Cariprazine.
Eluxadoline Eluxadoline The risk or severity of serotonin syndrome can be increased when Cariprazine is combined with Eluxadoline.
Trabectedin Injection Trabectedin Injection The metabolism of Cariprazine can be decreased when combined with Trabectedin.
Brivaracetam Injection Brivaracetam Injection The risk or severity of adverse effects can be increased when Brivaracetam is combined with Cariprazine.
Cobicistat Cobicistat The metabolism of Cariprazine can be decreased when combined with Cobicistat.
Midodrine Midodrine The risk or severity of hypertension can be increased when Midodrine is combined with Cariprazine.
Selexipag Selexipag Cariprazine may decrease the antihypertensive activities of Selexipag.
Pimavanserin Pimavanserin The risk or severity of adverse effects can be increased when Pimavanserin is combined with Cariprazine.
Diphenhydramine Injection Diphenhydramine Injection The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Cariprazine.
Furosemide Injection Furosemide Injection Cariprazine may decrease the antihypertensive activities of Furosemide.
Rucaparib Rucaparib The metabolism of Cariprazine can be decreased when combined with Rucaparib.
Doxepin (Insomnia) Doxepin (Insomnia) Cariprazine may increase the central nervous system depressant (CNS depressant) activities of Doxepin.
Deutetrabenazine Deutetrabenazine The risk or severity of adverse effects can be increased when Cariprazine is combined with Deutetrabenazine.
Valbenazine Valbenazine The metabolism of Valbenazine can be decreased when combined with Cariprazine.
Safinamide Safinamide The metabolism of Cariprazine can be decreased when combined with Safinamide.
Midostaurin Midostaurin The metabolism of Cariprazine can be decreased when combined with Midostaurin.
Enasidenib Enasidenib The metabolism of Cariprazine can be decreased when combined with Enasidenib.
Letermovir Letermovir The metabolism of Letermovir can be decreased when combined with Cariprazine.
Tetrabenazine Tetrabenazine The risk or severity of adverse effects can be increased when Cariprazine is combined with Tetrabenazine.
Buprenorphine Injection Buprenorphine Injection Cariprazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Lofexidine Lofexidine The therapeutic efficacy of Cariprazine can be increased when used in combination with Lofexidine.
Eliglustat Eliglustat The metabolism of Cariprazine can be decreased when combined with Eliglustat.
Encorafenib Encorafenib The metabolism of Encorafenib can be decreased when combined with Cariprazine.
Elagolix Elagolix The metabolism of Elagolix can be decreased when combined with Cariprazine.
Tafenoquine Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Cariprazine.
Cannabidiol Cannabidiol The risk or severity of adverse effects can be increased when Cannabidiol is combined with Cariprazine.
Dacomitinib Dacomitinib The metabolism of Cariprazine can be decreased when combined with Dacomitinib.
Stiripentol Stiripentol The metabolism of Cariprazine can be decreased when combined with Stiripentol.
Gilteritinib Gilteritinib The therapeutic efficacy of Cariprazine can be decreased when used in combination with Gilteritinib.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection Paclitaxel may increase the neurotoxic activities of Cariprazine.
Rifamycin Rifamycin The metabolism of Cariprazine can be decreased when combined with Rifamycin.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Cariprazine can be increased when combined with Emapalumab.
Siponimod Siponimod The risk or severity of hypertension can be increased when Cariprazine is combined with Siponimod.
Brexanolone Injection Brexanolone Injection The risk or severity of adverse effects can be increased when Cariprazine is combined with Brexanolone.
Solriamfetol Solriamfetol The risk or severity of hypertension can be increased when Solriamfetol is combined with Cariprazine.
Triclabendazole Triclabendazole The metabolism of Cariprazine can be decreased when combined with Triclabendazole.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Cariprazine.
Pitolisant Pitolisant The therapeutic efficacy of Pitolisant can be decreased when used in combination with Cariprazine.
Fedratinib Fedratinib The metabolism of Cariprazine can be decreased when combined with Fedratinib.
Phenytoin Injection Phenytoin Injection The risk or severity of adverse effects can be increased when Phenytoin is combined with Cariprazine.
Fosphenytoin Injection Fosphenytoin Injection The risk or severity of adverse effects can be increased when Fosphenytoin is combined with Cariprazine.
Lumateperone Lumateperone The risk or severity of adverse effects can be increased when Cariprazine is combined with Lumateperone.
Lasmiditan Lasmiditan The risk or severity of serotonin syndrome can be increased when Cariprazine is combined with Lasmiditan.
Cenobamate Cenobamate The serum concentration of Cariprazine can be decreased when it is combined with Cenobamate.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Cariprazine.
Selpercatinib Selpercatinib The risk or severity of hypertension can be increased when Cariprazine is combined with Selpercatinib.
Lemborexant Lemborexant The risk or severity of adverse effects can be increased when Cariprazine is combined with Lemborexant.
Fenfluramine Fenfluramine The risk or severity of serotonin syndrome can be increased when Fenfluramine is combined with Cariprazine.
Opicapone Opicapone The therapeutic efficacy of Opicapone can be decreased when used in combination with Cariprazine.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Cariprazine can be decreased when it is combined with Satralizumab.
Naxitamab-gqgk Injection Naxitamab-gqgk Injection The risk or severity of hypertension can be increased when Cariprazine is combined with Naxitamab.
Viloxazine Viloxazine The risk or severity of adverse effects can be increased when Cariprazine is combined with Viloxazine.
Theophylline Theophylline The metabolism of Cariprazine can be decreased when combined with Theophylline.
Fenoprofen Fenoprofen The risk or severity of hypertension can be increased when Fenoprofen is combined with Cariprazine.
Indomethacin Indomethacin The risk or severity of hypertension can be increased when Indomethacin is combined with Cariprazine.
Mefenamic Acid Mefenamic Acid The risk or severity of hypertension can be increased when Mefenamic acid is combined with Cariprazine.
Naproxen Naproxen The risk or severity of hypertension can be increased when Naproxen is combined with Cariprazine.
Tolmetin Tolmetin The risk or severity of hypertension can be increased when Tolmetin is combined with Cariprazine.
Sulindac Sulindac The risk or severity of hypertension can be increased when Sulindac is combined with Cariprazine.
Trazodone Trazodone The risk or severity of serotonin syndrome can be increased when Trazodone is combined with Cariprazine.
Hydroxyurea Hydroxyurea The metabolism of Cariprazine can be decreased when combined with Hydroxyurea.
Phenobarbital Phenobarbital The risk or severity of adverse effects can be increased when Phenobarbital is combined with Cariprazine.
Metaxalone Metaxalone The risk or severity of adverse effects can be increased when Metaxalone is combined with Cariprazine.
Levorphanol Levorphanol The risk or severity of adverse effects can be increased when Levorphanol is combined with Cariprazine.
Primidone Primidone The risk or severity of adverse effects can be increased when Primidone is combined with Cariprazine.
Methsuximide Methsuximide The risk or severity of adverse effects can be increased when Methsuximide is combined with Cariprazine.
Diethylpropion Diethylpropion Diethylpropion may decrease the sedative and stimulatory activities of Cariprazine.
Chlorpromazine Chlorpromazine The metabolism of Cariprazine can be decreased when combined with Chlorpromazine.
Diazepam Diazepam The risk or severity of adverse effects can be increased when Diazepam is combined with Cariprazine.
Oxazepam Oxazepam The risk or severity of adverse effects can be increased when Oxazepam is combined with Cariprazine.
Flurazepam Flurazepam The risk or severity of adverse effects can be increased when Flurazepam is combined with Cariprazine.
Clorazepate Clorazepate The risk or severity of adverse effects can be increased when Clorazepic acid is combined with Cariprazine.
Lorazepam Lorazepam The risk or severity of adverse effects can be increased when Lorazepam is combined with Cariprazine.
Phenoxybenzamine Phenoxybenzamine The risk or severity of hypertension can be increased when Phenoxybenzamine is combined with Cariprazine.
Amantadine Amantadine The therapeutic efficacy of Amantadine can be decreased when used in combination with Cariprazine.
Codeine Codeine The risk or severity of adverse effects can be increased when Codeine is combined with Cariprazine.
Meprobamate Meprobamate The risk or severity of adverse effects can be increased when Meprobamate is combined with Cariprazine.
Chlordiazepoxide Chlordiazepoxide The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Cariprazine.
Bromocriptine Bromocriptine Cariprazine may increase the vasoconstricting activities of Bromocriptine.
Metaproterenol Metaproterenol The risk or severity of hypertension can be increased when Orciprenaline is combined with Cariprazine.
Tranylcypromine Tranylcypromine The metabolism of Cariprazine can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Cariprazine can be decreased when combined with Phenelzine.
Procarbazine Procarbazine The metabolism of Cariprazine can be decreased when combined with Procarbazine.
Ergoloid Mesylates Ergoloid Mesylates Ergoloid mesylate may increase the vasoconstricting activities of Cariprazine.
Minocycline Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Cariprazine.
Prochlorperazine Prochlorperazine The risk or severity of adverse effects can be increased when Prochlorperazine is combined with Cariprazine.
Thioridazine Thioridazine The metabolism of Cariprazine can be decreased when combined with Thioridazine.
Trifluoperazine Trifluoperazine The risk or severity of adverse effects can be increased when Trifluoperazine is combined with Cariprazine.
Oxycodone Oxycodone The risk or severity of adverse effects can be increased when Oxycodone is combined with Cariprazine.
Methadone Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Cariprazine.
Oxybutynin Oxybutynin The metabolism of Cariprazine can be decreased when combined with Oxybutynin.
Benztropine Benztropine The therapeutic efficacy of Benzatropine can be decreased when used in combination with Cariprazine.
Maprotiline Maprotiline The risk or severity of adverse effects can be increased when Maprotiline is combined with Cariprazine.
Ibuprofen Ibuprofen The risk or severity of hypertension can be increased when Ibuprofen is combined with Cariprazine.
Trihexyphenidyl Trihexyphenidyl The therapeutic efficacy of Trihexyphenidyl can be decreased when used in combination with Cariprazine.
Orphenadrine Orphenadrine Cariprazine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Perphenazine Perphenazine The risk or severity of adverse effects can be increased when Perphenazine is combined with Cariprazine.
Fluphenazine Fluphenazine The risk or severity of adverse effects can be increased when Fluphenazine is combined with Cariprazine.
Phentermine Phentermine Phentermine may decrease the sedative and stimulatory activities of Cariprazine.
Methylphenidate Methylphenidate The risk or severity of adverse effects can be increased when Cariprazine is combined with Methylphenidate.
Amoxapine Amoxapine The metabolism of Amoxapine can be decreased when combined with Cariprazine.
Sulfasalazine Sulfasalazine The risk or severity of hypertension can be increased when Sulfasalazine is combined with Cariprazine.
Doxorubicin Doxorubicin The metabolism of Cariprazine can be decreased when combined with Doxorubicin.
Carbamazepine Carbamazepine The risk or severity of adverse effects can be increased when Carbamazepine is combined with Cariprazine.
Molindone Molindone The risk or severity of adverse effects can be increased when Molindone is combined with Cariprazine.
Methyldopa Methyldopa Cariprazine may decrease the antihypertensive activities of Methyldopa.
Clonidine Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Cariprazine.
Prazosin Prazosin Cariprazine may decrease the antihypertensive activities of Prazosin.
Hydralazine Hydralazine Cariprazine may decrease the antihypertensive activities of Hydralazine.
Cimetidine Cimetidine The metabolism of Cariprazine can be decreased when combined with Cimetidine.
Warfarin Warfarin The risk or severity of adverse effects can be increased when Cariprazine is combined with Warfarin.
Clonazepam Clonazepam The risk or severity of adverse effects can be increased when Clonazepam is combined with Cariprazine.
Loperamide Loperamide The metabolism of Cariprazine can be decreased when combined with Loperamide.
Promethazine Promethazine The risk or severity of adverse effects can be increased when Promethazine is combined with Cariprazine.
Meclofenamate Meclofenamate The risk or severity of hypertension can be increased when Meclofenamic acid is combined with Cariprazine.
Loxapine Loxapine The risk or severity of adverse effects can be increased when Loxapine is combined with Cariprazine.
Chloroquine Chloroquine The metabolism of Cariprazine can be decreased when combined with Chloroquine.
Quinine Quinine The metabolism of Cariprazine can be decreased when combined with Quinine.
Ethosuximide Ethosuximide The risk or severity of adverse effects can be increased when Ethosuximide is combined with Cariprazine.
Chlorothiazide Chlorothiazide Cariprazine may decrease the antihypertensive activities of Chlorothiazide.
Chlorthalidone Chlorthalidone Cariprazine may decrease the antihypertensive activities of Chlorthalidone.
Metolazone Metolazone Cariprazine may decrease the antihypertensive activities of Metolazone.
Clindamycin Injection Clindamycin Injection Clindamycin may increase the neurotoxic activities of Cariprazine.
Secobarbital Secobarbital The risk or severity of adverse effects can be increased when Secobarbital is combined with Cariprazine.
Desipramine Desipramine The metabolism of Cariprazine can be decreased when combined with Desipramine.
Amitriptyline Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Cariprazine.
Imipramine Imipramine The metabolism of Cariprazine can be decreased when combined with Imipramine.
Quinidine Quinidine The metabolism of Quinidine can be decreased when combined with Cariprazine.
Procainamide Procainamide The metabolism of Procainamide can be decreased when combined with Cariprazine.
Isoniazid Isoniazid The risk or severity of serotonin syndrome can be increased when Isoniazid is combined with Cariprazine.
Disopyramide Disopyramide Cariprazine may increase the central nervous system depressant (CNS depressant) activities of Disopyramide.
Valproic Acid Valproic Acid The risk or severity of adverse effects can be increased when Valproic acid is combined with Cariprazine.
Tamoxifen Tamoxifen The metabolism of Cariprazine can be decreased when combined with Tamoxifen.
Butabarbital Butabarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Cariprazine.
Methimazole Methimazole The metabolism of Cariprazine can be decreased when combined with Methimazole.
Dextromethorphan Dextromethorphan The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Cariprazine.
Cyclobenzaprine Cyclobenzaprine The risk or severity of CNS depression can be increased when Cariprazine is combined with Cyclobenzaprine.
Niacin Niacin The metabolism of Cariprazine can be decreased when combined with Niacin.
Baclofen Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Cariprazine.
Doxylamine Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Cariprazine.
Cyproheptadine Cyproheptadine Cariprazine may increase the central nervous system depressant (CNS depressant) activities of Cyproheptadine.
Clemastine Clemastine The risk or severity of adverse effects can be increased when Clemastine is combined with Cariprazine.
Chlorpheniramine Chlorpheniramine The risk or severity of adverse effects can be increased when Chlorpheniramine is combined with Cariprazine.
Brompheniramine Brompheniramine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Cariprazine.
Meclizine Meclizine The risk or severity of adverse effects can be increased when Meclizine is combined with Cariprazine.
Hydrochlorothiazide Hydrochlorothiazide Cariprazine may decrease the antihypertensive activities of Hydrochlorothiazide.
Dantrolene Dantrolene The risk or severity of adverse effects can be increased when Dantrolene is combined with Cariprazine.
Chlorzoxazone Chlorzoxazone The risk or severity of adverse effects can be increased when Chlorzoxazone is combined with Cariprazine.
Carisoprodol Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Cariprazine.
Methocarbamol Methocarbamol The risk or severity of adverse effects can be increased when Methocarbamol is combined with Cariprazine.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) Cariprazine may decrease the antihypertensive activities of Propranolol.
Minoxidil Minoxidil Cariprazine may decrease the antihypertensive activities of Minoxidil.
Pseudoephedrine Pseudoephedrine Pseudoephedrine may decrease the sedative and stimulatory activities of Cariprazine.
Nortriptyline Nortriptyline The metabolism of Nortriptyline can be decreased when combined with Cariprazine.
Nadolol Nadolol The metabolism of Cariprazine can be decreased when combined with Nadolol.
Butorphanol Injection Butorphanol Injection The risk or severity of adverse effects can be increased when Butorphanol is combined with Cariprazine.
Nalbuphine Injection Nalbuphine Injection The risk or severity of adverse effects can be increased when Nalbuphine is combined with Cariprazine.
Trimethobenzamide Trimethobenzamide The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Cariprazine.
Flavoxate Flavoxate Cariprazine may increase the central nervous system depressant (CNS depressant) activities of Flavoxate.
Acetazolamide Acetazolamide The risk or severity of adverse effects can be increased when Acetazolamide is combined with Cariprazine.
Ketoconazole Ketoconazole The metabolism of Cariprazine can be decreased when combined with Ketoconazole.
Pyrantel Pyrantel The risk or severity of adverse effects can be increased when Cariprazine is combined with Pyrantel.
Vincristine Injection Vincristine Injection Vincristine may increase the neurotoxic activities of Cariprazine.
Captopril Captopril Cariprazine may decrease the antihypertensive activities of Captopril.
Isoxsuprine Isoxsuprine The risk or severity of hypertension can be increased when Cariprazine is combined with Isoxsuprine.
Vinblastine Vinblastine The metabolism of Cariprazine can be decreased when combined with Vinblastine.
Metoprolol Metoprolol The metabolism of Cariprazine can be decreased when combined with Metoprolol.
Hydroxyzine Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Cariprazine.
Thiothixene Thiothixene The risk or severity of adverse effects can be increased when Thiothixene is combined with Cariprazine.
Aspirin Aspirin The risk or severity of hypertension can be increased when Acetylsalicylic acid is combined with Cariprazine.
Salsalate Salsalate The risk or severity of hypertension can be increased when Salsalate is combined with Cariprazine.
Alprazolam Alprazolam The risk or severity of adverse effects can be increased when Alprazolam is combined with Cariprazine.
Temazepam Temazepam The risk or severity of adverse effects can be increased when Temazepam is combined with Cariprazine.
Triazolam Triazolam The risk or severity of adverse effects can be increased when Triazolam is combined with Cariprazine.
Dicyclomine Dicyclomine Cariprazine may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine.
Hyoscyamine Hyoscyamine Cariprazine may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine.
Propantheline Propantheline Cariprazine may increase the central nervous system depressant (CNS depressant) activities of Propantheline.
Diltiazem Diltiazem Cariprazine may decrease the antihypertensive activities of Diltiazem.
Nifedipine Nifedipine The metabolism of Cariprazine can be decreased when combined with Nifedipine.
Timolol Timolol The metabolism of Cariprazine can be decreased when combined with Timolol.
Verapamil Verapamil The metabolism of Cariprazine can be decreased when combined with Verapamil.
Atenolol Atenolol The metabolism of Cariprazine can be decreased when combined with Atenolol.
Pindolol Pindolol The risk or severity of adverse effects can be increased when Pindolol is combined with Cariprazine.
Diflunisal Diflunisal The risk or severity of hypertension can be increased when Diflunisal is combined with Cariprazine.
Piroxicam Piroxicam The risk or severity of hypertension can be increased when Piroxicam is combined with Cariprazine.
Indapamide Indapamide Cariprazine may decrease the antihypertensive activities of Indapamide.
Pentamidine Injection Pentamidine Injection The metabolism of Cariprazine can be decreased when combined with Pentamidine.
Labetalol Labetalol The metabolism of Cariprazine can be decreased when combined with Labetalol.
Guanabenz Guanabenz The risk or severity of hypertension can be increased when Guanabenz is combined with Cariprazine.
Ketoprofen Ketoprofen The risk or severity of hypertension can be increased when Ketoprofen is combined with Cariprazine.
Pimozide Pimozide The metabolism of Cariprazine can be decreased when combined with Pimozide.
Enalapril Enalapril Cariprazine may decrease the antihypertensive activities of Enalapril.
Flurbiprofen Flurbiprofen The risk or severity of hypertension can be increased when Flurbiprofen is combined with Cariprazine.
Amiodarone Amiodarone The metabolism of Cariprazine can be decreased when combined with Amiodarone.
Buspirone Buspirone The risk or severity of serotonin syndrome can be increased when Buspirone is combined with Cariprazine.
Lovastatin Lovastatin The metabolism of Cariprazine can be decreased when combined with Lovastatin.
Mesalamine Mesalamine The risk or severity of hypertension can be increased when Mesalazine is combined with Cariprazine.
Diclofenac Diclofenac The risk or severity of hypertension can be increased when Diclofenac is combined with Cariprazine.
Fluoxetine Fluoxetine The serum concentration of Cariprazine can be increased when it is combined with Fluoxetine.
Nimodipine Nimodipine Cariprazine may decrease the antihypertensive activities of Nimodipine.
Clozapine Clozapine The metabolism of Cariprazine can be decreased when combined with Clozapine.
Estazolam Estazolam The risk or severity of adverse effects can be increased when Estazolam is combined with Cariprazine.
Idarubicin Idarubicin The metabolism of Cariprazine can be decreased when combined with Idarubicin.
Didanosine Didanosine Didanosine may increase the neurotoxic activities of Cariprazine.
Benazepril Benazepril Cariprazine may decrease the antihypertensive activities of Benazepril.
Etodolac Etodolac The risk or severity of hypertension can be increased when Etodolac is combined with Cariprazine.
Felodipine Felodipine The metabolism of Cariprazine can be decreased when combined with Felodipine.
Fosinopril Fosinopril Cariprazine may decrease the antihypertensive activities of Fosinopril.
Nabumetone Nabumetone The risk or severity of hypertension can be increased when Nabumetone is combined with Cariprazine.
Quinapril Quinapril Cariprazine may decrease the antihypertensive activities of Quinapril.
Ramipril Ramipril Cariprazine may decrease the antihypertensive activities of Ramipril.
Simvastatin Simvastatin The metabolism of Cariprazine can be decreased when combined with Simvastatin.
Amlodipine Amlodipine Cariprazine may decrease the antihypertensive activities of Amlodipine.
Teniposide Injection Teniposide Injection Teniposide may increase the neurotoxic activities of Cariprazine.
Lisinopril Lisinopril Cariprazine may decrease the antihypertensive activities of Lisinopril.
Oxaprozin Oxaprozin The risk or severity of hypertension can be increased when Oxaprozin is combined with Cariprazine.
Sotalol Sotalol The metabolism of Sotalol can be decreased when combined with Cariprazine.
Bisoprolol Bisoprolol Cariprazine may decrease the antihypertensive activities of Bisoprolol.
Zolpidem Zolpidem Cariprazine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Doxazosin Doxazosin Cariprazine may decrease the antihypertensive activities of Doxazosin.
Terazosin Terazosin Cariprazine may decrease the antihypertensive activities of Terazosin.
Isradipine Isradipine Cariprazine may decrease the antihypertensive activities of Isradipine.
Omeprazole Omeprazole The metabolism of Cariprazine can be decreased when combined with Omeprazole.
Cisapride Cisapride The metabolism of Cariprazine can be decreased when combined with Cisapride.
Gabapentin Gabapentin The risk or severity of adverse effects can be increased when Gabapentin is combined with Cariprazine.
Fluvastatin Fluvastatin The metabolism of Cariprazine can be decreased when combined with Fluvastatin.
Venlafaxine Venlafaxine The metabolism of Cariprazine can be decreased when combined with Venlafaxine.
Stavudine Stavudine Stavudine may increase the neurotoxic activities of Cariprazine.
Fluvoxamine Fluvoxamine The metabolism of Cariprazine can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone The risk or severity of adverse effects can be increased when Nefazodone is combined with Cariprazine.
Lamotrigine Lamotrigine The risk or severity of adverse effects can be increased when Lamotrigine is combined with Cariprazine.
Losartan Losartan Cariprazine may decrease the antihypertensive activities of Losartan.
Tramadol Tramadol The risk or severity of serotonin syndrome can be increased when Tramadol is combined with Cariprazine.
Vinorelbine Injection Vinorelbine Injection The metabolism of Cariprazine can be decreased when combined with Vinorelbine.
Moexipril Moexipril Cariprazine may decrease the antihypertensive activities of Moexipril.
Lansoprazole Lansoprazole The metabolism of Cariprazine can be decreased when combined with Lansoprazole.
Nicardipine Nicardipine The metabolism of Cariprazine can be decreased when combined with Nicardipine.
Bupropion Bupropion The metabolism of Cariprazine can be decreased when combined with Bupropion.
Ticlopidine Ticlopidine The metabolism of Cariprazine can be decreased when combined with Ticlopidine.
Saquinavir Saquinavir The metabolism of Cariprazine can be decreased when combined with Saquinavir.
Nisoldipine Nisoldipine Cariprazine may decrease the antihypertensive activities of Nisoldipine.
Riluzole Riluzole The risk or severity of adverse effects can be increased when Riluzole is combined with Cariprazine.
Ritonavir Ritonavir The serum concentration of Cariprazine can be increased when it is combined with Ritonavir.
Clomipramine Clomipramine The metabolism of Cariprazine can be decreased when combined with Clomipramine.
Mirtazapine Mirtazapine Cariprazine may increase the serotonergic activities of Mirtazapine.
Trandolapril Trandolapril Cariprazine may decrease the antihypertensive activities of Trandolapril.
Topiramate Topiramate The risk or severity of adverse effects can be increased when Topiramate is combined with Cariprazine.
Valsartan Valsartan Cariprazine may decrease the antihypertensive activities of Valsartan.
Pramipexole Pramipexole Cariprazine may increase the sedative activities of Pramipexole.
Donepezil Donepezil The risk or severity of adverse effects can be increased when Donepezil is combined with Cariprazine.
Nelfinavir Nelfinavir The metabolism of Cariprazine can be decreased when combined with Nelfinavir.
Carvedilol Carvedilol Cariprazine may decrease the antihypertensive activities of Carvedilol.
Selegiline Selegiline The metabolism of Cariprazine can be decreased when combined with Selegiline.
Bicalutamide Bicalutamide The metabolism of Cariprazine can be decreased when combined with Bicalutamide.
Sertraline Sertraline The risk or severity of adverse effects can be increased when Sertraline is combined with Cariprazine.
Propafenone Propafenone The metabolism of Cariprazine can be decreased when combined with Propafenone.
Irbesartan Irbesartan Cariprazine may decrease the antihypertensive activities of Irbesartan.
Tamsulosin Tamsulosin The metabolism of Cariprazine can be decreased when combined with Tamsulosin.
Ropinirole Ropinirole Cariprazine may increase the sedative activities of Ropinirole.
Finasteride Finasteride The risk or severity of hypertension can be increased when Finasteride is combined with Cariprazine.
Quetiapine Quetiapine The risk or severity of adverse effects can be increased when Quetiapine is combined with Cariprazine.
Cetirizine Cetirizine The risk or severity of adverse effects can be increased when Cetirizine is combined with Cariprazine.
Paroxetine Paroxetine The metabolism of Cariprazine can be decreased when combined with Paroxetine.
Tolcapone Tolcapone The therapeutic efficacy of Tolcapone can be decreased when used in combination with Cariprazine.
Citalopram Citalopram The risk or severity of adverse effects can be increased when Citalopram is combined with Cariprazine.
Efavirenz Efavirenz The risk or severity of adverse effects can be increased when Efavirenz is combined with Cariprazine.
Sildenafil Sildenafil The metabolism of Cariprazine can be decreased when combined with Sildenafil.
Celecoxib Celecoxib The metabolism of Cariprazine can be decreased when combined with Celecoxib.
Rosiglitazone Rosiglitazone The metabolism of Cariprazine can be decreased when combined with Rosiglitazone.
Tolterodine Tolterodine Cariprazine may increase the central nervous system depressant (CNS depressant) activities of Tolterodine.
Thalidomide Thalidomide Cariprazine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Balsalazide Balsalazide The risk or severity of hypertension can be increased when Balsalazide is combined with Cariprazine.
Nateglinide Nateglinide The metabolism of Cariprazine can be decreased when combined with Nateglinide.
Galantamine Galantamine The metabolism of Cariprazine can be decreased when combined with Galantamine.
Levetiracetam Levetiracetam The risk or severity of adverse effects can be increased when Levetiracetam is combined with Cariprazine.
Rabeprazole Rabeprazole The metabolism of Cariprazine can be decreased when combined with Rabeprazole.
Terbinafine Terbinafine The metabolism of Cariprazine can be decreased when combined with Terbinafine.

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