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Methocarbamol

Methocarbamol is a muscle relaxant used alongside rest and physical therapy to ease discomfort from acute, painful musculoskeletal conditions, and it comes as tablets, an oral suspension and an injection.

Brand names RobaxinTanlorAtmeksiMethocarb 500-EZS
Drug class Muscle Relaxant
Rx Forms 3
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026 Content updated Oct 2, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 181 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

✓No current FDA shortage listed · checked Oct 6, 2026 🚨Class I recall on record · 2
Methocarbamol at a glance The quick version — the full detail is in the Patient Information Guide below.
Dr. Brian Staiger, PharmD, BCPS
The Pharmacist’s Take By · Clinical pharmacist · Written

Methocarbamol is a muscle relaxant used alongside rest and physical therapy for sudden, short-term muscle and bone pain such as a back strain. It likely works through a general calming effect on the brain and nerves rather than on the muscle itself, and it is a familiar older standby, on the U.S. market since the 1950s and available as a generic. Most people tolerate it reasonably well, and the effect they notice most is drowsiness or slowed thinking. The real danger is stacking that sedation with alcohol, opioids, benzodiazepines or tricyclic antidepressants, so skip alcohol and hold off on driving until you know how it affects you.

Clinical pearls

  • Shake Atmeksi oral suspension for at least 30 seconds before every dose so each dose has the right amount of medicine.
  • Tell your prescriber about liver disease or dialysis, since both slow how quickly your body clears methocarbamol.
  • It does not loosen the muscle directly, so keep up the rest, stretching and physical therapy it is meant to support.
  • The NSAID boxed warning on this page belongs to a diclofenac combination product, not to methocarbamol on its own.
⚠️ FDA Boxed Warning — the FDA’s strongest safety alert ▾

WARNING: RISK OF SERIOUS CARDIOVASCULAR AND GASTROINTESTINAL EVENTS Cardiovascular Thrombotic Events Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may occur early in treatment and may increase with duration of use (see WARNINGS ). Diclofenac sodium delayed-release tablets are contraindicated in the setting of coronary artery bypass graft (CABG) surgery (s...

Read the full warning on DailyMed →
How you get itPrescription only
Comes asTablet, Injection, Oral suspension
Earliest FDA record1957
Companies listing it with the FDA63
FDA label last updatedMar 13, 2026
FDA’s strongest warning (boxed)Yes, read the warning

Patient information guide A plain-language walkthrough of Methocarbamol, written from its FDA label.

What Methocarbamol is used for

▾

Methocarbamol is used for one main purpose across its products.

  • Methocarbamol tablets, including Tanlor: an add-on to rest, physical therapy and other measures for discomfort from acute, painful musculoskeletal conditions.
  • Methocarbamol injection, including Robaxin (intramuscular or intravenous): the same use.
  • Atmeksi oral suspension: the same use, in patients 16 and older.

How Methocarbamol works

▾

How methocarbamol works in humans has not been established. It may be due to general central nervous system (CNS) depression, and it may be related to its sedative properties.

It does not act directly on the contracting machinery of muscle, the motor end plate or the nerve fiber, and it does not directly relax tense skeletal muscles.

Methocarbamol dosage

▾

Methocarbamol is taken by mouth as tablets or Atmeksi suspension, or given by injection into a muscle or vein. Oral products are taken several times a day. A higher daily amount is used for the first 48 to 72 hours, then usually lowered.

  • Atmeksi: shake for at least 30 seconds before use. Food lowered and delayed absorption in the label's study.
  • Injection (including Robaxin): given by a healthcare professional for no more than 3 consecutive days, except in tetanus. A course can be repeated after 48 drug-free hours.

Follow your prescriber's directions and your product's label.

Dosing details from the FDA-approved label

From the Methocarbamol prescribing information (“Dosage and Administration”). Doses are set by your prescriber for your product, condition, kidney function and age — never change a dose on your own.

  • Adults, oral tablets (Methocarbamol Tablets, USP, 500 mg)
    • Initial dosage: 3 tablets four times daily
    • Maintenance dosage: 2 tablets four times daily
    • Six grams a day are recommended for the first 48 to 72 hours of treatment
    • Thereafter the dosage can usually be reduced to approximately 4 grams a day
    • Maximum: For severe conditions 8 grams a day may be administered
  • Adults, oral tablets (Methocarbamol Tablets, USP, 750 mg)
    • Initial dosage: 2 tablets four times daily
    • Maintenance dosage: 1 tablet every 4 hours or 2 tablets three times daily
    • Six grams a day are recommended for the first 48 to 72 hours of treatment
    • Thereafter approximately 4 grams a day
    • Maximum: For severe conditions 8 grams a day may be administered
  • Adults, oral suspension (Atmeksi)
    • Initial dosage: 1,500 mg (10 mL) 4 times daily
    • Maintenance dosage: 750 mg (5 mL) every 4 hours or 1,500 mg (10 mL) 3 times daily
    • Six grams a day are recommended for the first 48 to 72 hours
    • Thereafter approximately 4 grams a day
    • Maximum: For severe conditions 8 grams a day may be administered
    • Shake the drug product for at least 30 seconds before administration
  • Adults, oral tablets (Tanlor)
    • Initial dosage: 1½ tablets 4 times daily
    • Maintenance dosage: 1 tablet 4 times daily
    • Six grams a day are recommended for the first 48 to 72 hours
    • Thereafter approximately 4 grams a day
    • Maximum: For severe conditions 8 grams a day may be administered
  • Adults, injection: moderate symptoms
    • One dose of 1 gram (one 10 mL vial) may be adequate
    • Ordinarily need not be repeated, as the oral form will usually sustain the relief
    • Maximum: Total adult dosage should not exceed 30 mL (3 vials) a day for more than 3 consecutive days except in tetanus
    • If condition persists, a like course may be repeated after a drug-free interval of 48 hours
  • Adults, injection: severest cases or postoperative conditions when oral administration is not feasible
    • Additional doses of 1 gram may be repeated every 8 hours
    • Maximum: 3 g/day for no more than 3 consecutive days
    • IV: maximum rate of three mL per minute undiluted; one vial as a single dose not diluted to more than 250 mL; IM: not more than five mL into each gluteal region
  • Adults, tetanus (injection)
    • Inject one or two vials into the tubing of the indwelling needle
    • An additional 10 mL or 20 mL may be added to the infusion bottle for a total of up to 30 mL (three vials) as the initial dose
    • Repeat every six hours until a nasogastric tube can be inserted, then crushed tablets in water or saline via the tube
    • Maximum: Total daily oral doses up to 24 grams may be required
  • Pediatric patients, tetanus (injection)
    • Minimum initial dose of 15 mg/kg or 500 mg/m2
    • May be repeated every six hours, if required
    • Maximum: Total dose should not exceed 1.8 g/m2 for 3 consecutive days
Read the label’s full dosing text

2 DOSAGE AND ADMINISTRATION Adults Initial dosage: 1,500 mg (10 mL) 4 times daily Maintenance dosage: 750 mg (5 mL) every 4 hours or 1,500 mg (10 mL) 3 times daily Six grams a day are recommended for the first 48 to 72 hours of treatment. (For severe conditions 8 grams a day may be administered). Thereafter, the dosage can usually be reduced to approximately 4 grams a day. 2.1 Important Dosage and Administration Instructions Initial dosage: 1,500 mg (10 mL) 4 times daily Maintenance dosage: 750 mg (5 mL) every 4 hours or 1,500 mg (10 mL) 3 times daily Six grams a day are recommended for the first 48 to 72 hours of treatment. (For severe conditions 8 grams a day may be administered). Thereafter, the dosage can usually be reduced to approximately 4 grams a day. Inform the patient to shake the drug product for at least 30 seconds to ensure it is uniform before administration.

2.1 Important Dosage and Administration Instructions Initial dosage: 1,500 mg (10 mL) 4 times daily Maintenance dosage: 750 mg (5 mL) every 4 hours or 1,500 mg (10 mL) 3 times daily Six grams a day are recommended for the first 48 to 72 hours of treatment. (For severe conditions 8 grams a day may be administered). Thereafter, the dosage can usually be reduced to approximately 4 grams a day. Inform the patient to shake the drug product for at least 30 seconds to ensure it is uniform before administration.

Read the full Dosage and Administration section on DailyMed →

Methocarbamol side effects

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Drowsiness, nausea and blurred vision are listed among the symptoms of methocarbamol overdose, so they are worth watching for.

Seek urgent help for breathing problems, seizures, very low blood pressure signs, or being unable to stay awake.

Methocarbamol warnings and precautions

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  • Drowsiness and impaired alertness: Atmeksi may affect your ability to drive or use machinery. Wait until you know how it affects you.
  • Alcohol and other CNS depressants: Methocarbamol can add to their effects.
  • Overdose: Deaths have been reported with methocarbamol alone and with other CNS depressants, including alcohol.

Methocarbamol interactions

▾

Be careful with anything that slows the brain or nervous system.

  • Alcohol: effects can be added together.
  • Benzodiazepines: additive sedating effect.
  • Opioids: additive sedating effect.
  • Tricyclic antidepressants: additive sedating effect, even at recommended doses.

Interactions listed in the FDA-approved label

From the Methocarbamol prescribing information (“Drug Interactions”): what the manufacturer studied or reported to the FDA.

  • Anticoagulants (e.g., warfarin), antiplatelet agents, SSRIs, SNRIs: Diclofenac and anticoagulants have a synergistic effect on bleeding, with increased risk of serious bleeding compared with either drug alone. Monitor patients for signs of bleeding.
  • Aspirin: Concomitant use does not produce greater therapeutic effect than NSAID alone and significantly increases GI adverse reactions. Not generally recommended because of increased risk of bleeding; diclofenac is not a substitute for low dose aspirin for cardiovascular protection.
  • ACE inhibitors, angiotensin receptor blockers, beta-blockers: NSAIDs may diminish the antihypertensive effect; with ACE inhibitors or ARBs in elderly, volume-depleted or renally impaired patients, renal function may deteriorate, including possible acute renal failure. Monitor blood pressure; monitor for worsening renal function in at-risk patients; keep patients adequately hydrated; assess renal function at start and periodically.
  • Diuretics (loop and thiazide): NSAIDs reduced the natriuretic effect of loop diuretics (e.g., furosemide) and thiazide diuretics in some patients. Observe for signs of worsening renal function and assure diuretic efficacy including antihypertensive effects.
  • Digoxin: Diclofenac has been reported to increase serum digoxin concentration and prolong its half-life. Monitor serum digoxin levels.
  • Lithium: NSAIDs have produced elevations in plasma lithium levels and reductions in renal lithium clearance; mean minimum lithium concentration increased 15% and renal clearance decreased by approximately 20%. Monitor patients for signs of lithium toxicity.
  • Methotrexate: Concomitant use may increase the risk for methotrexate toxicity (e.g., neutropenia, thrombocytopenia, renal dysfunction). Monitor patients for methotrexate toxicity.
  • Cyclosporine: Concomitant use may increase cyclosporine's nephrotoxicity. Monitor patients for signs of worsening renal function.
  • Other NSAIDs or salicylates (e.g., diflunisal, salsalate): Concomitant use increases the risk of GI toxicity, with little or no increase in efficacy. Concomitant use is not recommended.
  • Pemetrexed: Concomitant use may increase the risk of pemetrexed-associated myelosuppression, renal, and GI toxicity. In patients with creatinine clearance 45 to 79 mL/min, monitor for myelosuppression, renal and GI toxicity; avoid short half-life NSAIDs (e.g., diclofenac) for two days before, the day of, and two days following pemetrexed; for longer half-life NSAIDs interrupt dosing for at least five days before, the day of, and two days following.
Read the label’s full interactions text

Drug Interactions See Table 2 for clinically significant drug interactions with diclofenac. Table 2. Clinically Significant Drug Interactions with Diclofenac Drugs That Interfere with Hemostasis Clinical Impact: Diclofenac and anticoagulants such as warfarin have a synergistic effect on bleeding. The concomitant use of diclofenac and anticoagulants have an increased risk of serious bleeding compared to the use of either drug alone. Serotonin release by platelets plays an important role in hemostasis. Case-control and cohort epidemiological studies showed that concomitant use of drugs that interfere with serotonin reuptake and an NSAID may potentiate the risk of bleeding more than an NSAID alone. Intervention: Monitor patients with concomitant use of diclofenac sodium delayed-release tablets with anticoagulants (e.g., warfarin), antiplatelet agents (e.g., aspirin), selective serotonin reuptake inhibitors (SSRIs), and serotonin norepinephrine reuptake inhibitors (SNRIs) for signs of bleeding (see WARNINGS: Hematologic Toxicity ). Aspirin Clinical Impact: Controlled clinical studies showed that the concomitant use of NSAIDs and analgesic doses of aspirin does not produce any greater therapeutic effect than the use of NSAIDs alone. In a clinical study, the concomitant use of an NSAID and aspirin was associated with a significantly increased incidence of GI adverse reactions as compared to use of the NSAID alone (see WARNINGS: Gastrointestinal Bleeding, Ulceration, and Perforation ). Intervention: Concomitant use of diclofenac sodium delayed-release tablets and analgesic doses of aspirin is not generally recommended because of the increased risk of bleeding (see WARNINGS: Hematologic Toxicity ). Diclofenac sodium delayed-release tablets are not a substitute for low dose aspirin for cardiovascular protection.

Excerpted — the section continues on the label. Read the full Drug Interactions section on DailyMed →

Not a complete list. The label covers the interactions the manufacturer studied or reported, and our own interaction database does not cover every medicine either. Bring your full medication list, including vitamins and herbal products, to your pharmacist.

Before taking Methocarbamol

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  • Atmeksi: not shown safe and effective under age 16.
  • Liver disease: clearance was reduced about 70% in people with cirrhosis.
  • Kidney problems: clearance was reduced about 40% in people on dialysis.
  • Older adults: the half-life was slightly longer.
  • Pregnancy: limited case-report data did not identify an increased risk of major birth defects or miscarriage.
  • Breastfeeding: there are no human data. Weigh the benefits of breastfeeding against your need for the medicine.

Methocarbamol overdose

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Overdose can cause breathing problems, nausea, drowsiness, blurred vision, low blood pressure, seizures, coma and death. Treatment is supportive care, such as monitoring breathing and giving IV fluids. Call Poison Help at 1-800-222-1222.

How your body processes Methocarbamol

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In the Atmeksi study, oral methocarbamol was absorbed quickly, peaking in under an hour. Food lowered the peak level by 51% and total exposure by 31%, and delayed the peak to about 1.6 hours.

The half-life was about 1.3 to 1.5 hours. The body breaks it down by dealkylation and hydroxylation, and essentially all metabolites leave in the urine. Small amounts leave unchanged.

How to store Methocarbamol

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Store at 20º to 25º C (68º to 77º F) .

Written from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

20

Supplements & herbs that interact with Methocarbamol

20 supplements and herbal products have documented interactions with Methocarbamol in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.

Severity mix
  • Major · 2
  • Moderate · 9
  • Minor · 9
Every supplement checked against Methocarbamol — ranked by severity The full interaction hub: 2 major · 9 moderate · 9 minor · every one linked to its full report. Check Methocarbamol against your exact supplements

Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.

Methocarbamol: pharmacist answers to common questions

Quick, plain-English answers to the questions patients ask most about Methocarbamol — the kind of thing our pharmacy team would talk through with you at the counter.

What is methocarbamol for?

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It's used along with rest and physical therapy to ease discomfort from sudden, painful muscle and bone conditions. It's an add-on, not a replacement for those other measures.

Can I drink alcohol while taking it?

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It's best to avoid it. Methocarbamol can add to the effects of alcohol and other sedating medicines. Deaths have been reported with overdose, including when alcohol was involved.

Can I drive after taking it?

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Be careful. It can affect your mental and physical abilities. Wait until you know how it affects you before driving or using machinery.

How should I take it?

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Tablets and Atmeksi suspension are taken by mouth several times a day. Usually a higher amount is used for the first couple of days, then less. If you use Atmeksi, shake it well for at least 30 seconds first. Follow your own label.

Is it safe in pregnancy or while breastfeeding?

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Limited reports from decades of use haven't shown an increased risk of major birth defects or miscarriage. There are no human data on breast milk, so talk with your prescriber about the benefits and risks first.

What if I take too much?

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Get help right away. Call Poison Help at 1-800-222-1222 or seek emergency care. Too much can cause slowed breathing, seizures and coma.

Is Methocarbamol available over the counter?

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No. Methocarbamol is a prescription medicine: every Methocarbamol product listed with the FDA is prescription only, so it is not sold over the counter. Your prescriber decides whether it is appropriate for you, and your pharmacist dispenses it.

When was Methocarbamol first available?

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The earliest FDA record we hold for Methocarbamol is from 1957: its first approval in Drugs@FDA or its earliest product listing in the NDC Directory, whichever is older. Many older medicines were in use before their first formal FDA approval, so this is the earliest date on record, not necessarily when Methocarbamol was first used.

Who makes Methocarbamol?

▾
63 companies currently list Methocarbamol products in the FDA's NDC Directory, including Bryant Ranch Prepack, A-S Medication Solutions, PD-Rx Pharmaceuticals, Inc.. That count includes repackagers and distributors as well as manufacturers (companies that sell only the raw ingredient are not counted), so fewer companies actually make it; the label on your bottle names the one that supplied yours.

Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

More about Methocarbamol on HelloPharmacist

Detailed data & references for Methocarbamol Forms & strengths, pricing, billing codes, manufacturers, safety reports and sourcing — the data behind the page. Most people can stop here. Each section below opens on a tap.

Methocarbamol forms and strengths (how it comes)

Methocarbamol is available in 3 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Need a version that does not list lactose, a gluten source, a dye or gelatin? Inactive ingredients differ by manufacturer: see Methocarbamol inactive ingredients by manufacturer.

Tablet

By mouth
Brands Tanlor
How this form is used
What it may be used for
  • Tanlor and methocarbamol tablets are used as an add-on to rest, physical therapy and other measures for discomfort from acute, painful musculoskeletal conditions.
Important instructions
  • Tanlor and methocarbamol tablets are taken by mouth several times a day.
  • The label describes a higher amount for the first 48 to 72 hours, with the daily amount usually reduced afterward.
  • Methocarbamol tablets come in 500 mg and 750 mg strengths, and the number of tablets per dose depends on the strength, so follow your own label.
Available strengths 3 strengths
374 FDA-listed product records ⓘ

Injection

Into a muscle · Into a vein
Brands Robaxin
How this form is used
What it may be used for
  • Robaxin and methocarbamol injection are used as an add-on to rest, physical therapy and other measures for discomfort from acute, painful musculoskeletal conditions.
Important instructions
  • Robaxin and methocarbamol injection are for intravenous and intramuscular use only.
  • Robaxin and methocarbamol injection total adult use should not go beyond 3 consecutive days, except in treating tetanus.
  • If the condition persists, the label allows a like course to be repeated after a 48-hour drug-free interval.
  • With Robaxin and methocarbamol injection, the oral form will usually keep up the relief started by the injection.
Available strengths 2 strengths
26 FDA-listed product records ⓘ

Oral suspension

By mouth
Brands Atmeksi
How this form is used
What it may be used for
  • Atmeksi is used as an add-on to rest, physical therapy and other measures for discomfort from acute, painful musculoskeletal conditions in patients 16 and older.
Important instructions
  • Atmeksi should be shaken for at least 30 seconds before each use.
  • Atmeksi is taken by mouth several times a day, with a higher amount for the first 48 to 72 hours and usually less afterward.
  • Food slowed and reduced absorption of Atmeksi in the label's study.
Available strengths 1 strength
1 FDA-listed product record ⓘ

Methocarbamol on the U.S. market: products, makers and brands

How Methocarbamol appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

63 companies list 212 Methocarbamol product records with the FDA, mostly as tablet, injection, oral suspension; the earliest marketing or approval year on record is 1957. Brand names on the directory include Robaxin, Tanlor, Atmeksi and 1 more; the rest are generics.

3
Dose forms ⓘ
63
Labelers (makers, repackagers, distributors)
7
Brand names
212
FDA-listed product records ⓘ
1957
Earliest FDA record ⓘ

FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

Also listed with the FDA, not a patient dose form: Powder (17) · Kit (1) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

Bryant Ranch Prepack11%
A-S Medication Solutions8%
PD-Rx Pharmaceuticals, Inc.7%
Proficient Rx LP6%
Asclemed USA, Inc.5%
Preferred Pharmaceuticals Inc.4%
Other makers59%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

How widely Methocarbamol is used (Medicaid data)

A general measure of how commonly Methocarbamol is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Methocarbamol is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

2,261,221
Medicaid prescriptions filled (Q1–Q4 2025)
$28.9M gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Methocarbamol prescribed? Of the 1,601 medications we measure, Methocarbamol ranks #97 by Medicaid prescriptions — more than 94% of them.

Where Methocarbamol ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5

Utilization by Methocarbamol product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

The 500 mg oral tablet is the most-dispensed Methocarbamol product — about 55% of these Medicaid prescriptions.

methocarbamol 500 MG Oral Tablet Most dispensed

1,245,001 Medicaid prescriptions (Q1–Q4 2025) 55% of Methocarbamol prescriptions shown $11M gross reimbursement (before rebates) ≈ $8.83 per prescription (gross)

Summed across the 15 of 547 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 197943

methocarbamol 750 MG Oral Tablet

1,002,793 Medicaid prescriptions (Q1–Q4 2025) 44% of Methocarbamol prescriptions shown $9.8M gross reimbursement (before rebates) ≈ $9.75 per prescription (gross)

Summed across the 14 of 476 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 197944

10 ML methocarbamol 100 MG/ML Injection

7,894 Medicaid prescriptions (Q1–Q4 2025) <1% of Methocarbamol prescriptions shown $257,835 gross reimbursement (before rebates) ≈ $33 per prescription (gross)

Summed across the 11 of 34 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 238175

methocarbamol 1000 MG Oral Tablet

5,533 Medicaid prescriptions (Q1–Q4 2025) <1% of Methocarbamol prescriptions shown $7.8M gross reimbursement (before rebates) ≈ $1,413 per prescription (gross)

Summed across the 2 of 7 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2611794

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Methocarbamol, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 42 of 1,064 listed Methocarbamol NDCs with Medicaid activity.

Compare Methocarbamol products

A representative set of FDA-listed product records for Methocarbamol — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Showing 200 of 212 products — FDA National Drug Code Directory. See every product, package size and price: browse all 212 Methocarbamol NDCs →

Methocarbamol side effects reported to the FDA (FAERS)

After a medicine reaches the market, patients, doctors and drugmakers can send the FDA reports of problems they think may be linked to it. Here’s what’s been reported for Methocarbamol — a signal of what to watch for, not proof the drug caused it.

The effects most often named in FDA reports that mention Methocarbamol are pain, nausea, fatigue; about 62% of the reports were classed as serious. These are voluntary reports, so they show what people report, not how often it happens.

22,591
Reports mentioning it
62%
Reported as serious
12
Distinct effects shown
Most reported effects
Pain
1,731
Nausea
1,678
Fatigue
1,650
Headache
1,298
Diarrhoea
1,184
Fall
1,095
Dyspnoea
1,055
Arthralgia
1,036
Dizziness
969
Back Pain
929
Age groups
Adult · 2,749Elderly · 1,386Child · 21Adolescent · 18Neonate · 5Infant · 2

Source: openFDA, from the FDA Adverse Event Reporting System (FAERS). These are voluntary reports — they don’t prove the drug caused the effect, and counts reflect how often something was reported, not how often it actually happens. Reports also often name the very problem the medicine is taken for — a common reason to file one is that the drug didn’t help — so for a pain reliever you may see “pain” high on the list; that points to why the report was filed, not to the drug causing the symptom. This counts every report that lists Methocarbamol in any role, so the total runs higher than the FDA’s official dashboard, which counts only cases where the drug is the suspect. For the authoritative figures, see the FDA FAERS Public Dashboard. Always talk to your pharmacist or doctor.

Methocarbamol FDA approval history

How Methocarbamol went from FDA review to the pharmacy shelf — the key milestones in its regulatory journey.

Methocarbamol was first approved by the FDA in 1957 (Brand: ROBAXIN-750 · Endo Operations); the first generic version was approved in 1974. It remains available in U.S. pharmacies today.

1957
Brand approved
Brand: ROBAXIN-750 · Endo Operations
1974
First generic approved
Lower-cost ANDA competition begins
2026
Available today
Active in U.S. pharmacies

Source: Drugs@FDA.

Methocarbamol recall history

A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.

The FDA’s enforcement reports list 2 Methocarbamol recalls since July 2021. Both are still ongoing or began in the last six months. A recall names specific lots from one company, so check the lot number on your own bottle rather than assuming every product is affected; your pharmacist can check whether your supply came from an affected lot.

Ongoing Class II Mar 21, 2025 · Somerset Therapeutics Private Limited
Lack of Assurance of Sterility: Media fill with bacterial contamination
  • Methocarbamol Injection USP 1,000 mg/10 mL (100 mg/mL), 10 mL Single Dose Vial, Rx Only, Manufactured for: Somerset Therapeutics, LLC, Somerset, NJ 08873, NDC 70069-101-25 (immediate carton) and 7006… Lots: NDC 70069-101-25; A240304, A240305, A240320, A240322, A240334, A240335, A240340, exp. date 05/2026; A240342, A240347, A240385, A240391, exp. date 06/2026; NDC 70069-101-05; A240326, exp. date 05/2026 FDA record D-0354-2025 →
Ongoing Class I Feb 15, 2024 · Eugia US LLC
Presence of Particulate Matter
  • Methocarbamol Injection, USP 1000mg/10mL, (100mg/mL), 10 mL Single-Dose Vial packed 25 vials per carton, Rx Only, Mfd. in India for: Eugia US LLC. E. Windsor, NJ 08520, NDC 55150-223-10 Lots: Lot #: 3MC23011, Exp 11/30/2026 FDA record D-0440-2024 →

Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Sep 24, 2026.

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Methocarbamol RxCUI 6845 3 dose forms · 5 strengths
  1. Dose form (SCDF) Injection RxCUI 1740942 In current FDA listings
    Clinical drug / strength (SCD) 10 ML methocarbamol 100 MG/ML RxCUI 238175
  2. Dose form (SCDF) Oral Suspension RxCUI 2729334 In current FDA listings
    Clinical drug / strength (SCD) 150 MG/ML RxCUI 2729335
  3. Dose form (SCDF) Oral Tablet RxCUI 372831 In current FDA listings
    Clinical drug / strength (SCD) 500 MG RxCUI 197943 750 MG RxCUI 197944 1000 MG RxCUI 2611794

Look up RxCUI 6845 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

💵 What Methocarbamol costs pharmacies (NADAC benchmark)

The national average invoice price pharmacies pay for the drug itself, from CMS's NADAC survey (data as of Sep 30, 2026). This is a supply-cost benchmark — not a retail price and not what you'd pay at the counter.

FormStrengthPharmacy acquisition benchmark
Tablet · Oral 500 mg $0.039 per tablet NDC details & price history
Tablet · Oral 750 mg $0.043 per tablet NDC details & price history
Tablet, Film Coated · Oral 1000 mg $8.35 per tablet NDC details & price history
Why show this? Your out-of-pocket cost depends on insurance, pharmacy markup, and discounts — but the acquisition benchmark tells you whether the medication itself is inexpensive or costly, which strengths cost more per dose, and whether a cash-price quote is in a reasonable range. Each row links to the NDC-level record with its full price history.

Source: CMS National Average Drug Acquisition Cost (NADAC), a survey of retail pharmacy invoice prices. Benchmarks shown are the range across package sizes of a representative product for each form and strength — other manufacturers' products may differ.

Methocarbamol brand names

Methocarbamol is sold under 4 brand names in the FDA directory — Robaxin, Tanlor, Atmeksi, Methocarb 500-EZS. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.

Robaxin Tanlor Atmeksi Methocarb 500-EZS

Who makes Methocarbamol: manufacturers and labelers

63 companies list Methocarbamol products with the FDA. By number of product records, the largest are Bryant Ranch Prepack, A-S Medication Solutions, PD-Rx Pharmaceuticals, Inc.. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.

Bryant Ranch Prepack 24 A-S Medication Solutions 17 PD-Rx Pharmaceuticals, Inc. 14 Proficient Rx LP 12 Asclemed USA, Inc. 11 Preferred Pharmaceuticals Inc. 8 Aphena Pharma Solutions - Tennessee, LLC 7 Advanced Rx of Tennessee, LLC 6 NuCare Pharmaceuticals,Inc. 6 Remedyrepack Inc. 5 St. Mary's Medical Park Pharmacy 5 Advanced Rx Pharmacy of Tennessee, LLC 4 Cardinal Health 107, LLC 4 Coupler LLC 4 Direct Rx 4 Northwind Health Company, LLC 4 Phoenix Rx Llc 4 Bostal LLC 3 Hawaii Repack, Inc. 3 Redpharm Drug 3 American Health Packaging 2 Aurobindo Pharma Limited 2 AvPAK 2 Camber Pharmaceuticals, Inc. 2

…and 39 more on the FDA NDC directory.

Methocarbamol drug class (RxNorm)

Methocarbamol belongs to the Muscle Relaxant class.

Pharmacologic class Muscle Relaxant
Drug family (ATC) Carbamic acid esters

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

Sources for this Methocarbamol page

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Mar 13, 2026
🏭
Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Methocarbamol.
📈
Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
🚨
Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Methocarbamol after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
181
Finished products in the current FDA directory
212
Companies listing them (makers, repackagers, distributors)
63
FDA labeler codes behind them ⓘ
70
Linked representative label ⓘ
Rosemont Pharmaceuticals LLC
Linked label effective
Mar 13, 2026
Composite sections available
23
Linked SPL Set ID
62de7345-613b-4838-96e5-aceca3cea6b2
Linked SPL Document ID
4ce9560d-185c-1e28-e063-6294a90af77f
Open the linked representative label on DailyMed ↗
NDC package records associated with this linked SPL 1

How this page is built

HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. Rosemont Pharmaceuticals LLC is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →