Methocarbamol
Methocarbamol is a muscle relaxant used alongside rest and physical therapy to ease discomfort from acute, painful musculoskeletal conditions, and it comes as tablets, an oral suspension and an injection.
🧬 Where this information comes from Click to expand
The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 181 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →
Methocarbamol is a muscle relaxant used alongside rest and physical therapy for sudden, short-term muscle and bone pain such as a back strain. It likely works through a general calming effect on the brain and nerves rather than on the muscle itself, and it is a familiar older standby, on the U.S. market since the 1950s and available as a generic. Most people tolerate it reasonably well, and the effect they notice most is drowsiness or slowed thinking. The real danger is stacking that sedation with alcohol, opioids, benzodiazepines or tricyclic antidepressants, so skip alcohol and hold off on driving until you know how it affects you.
Clinical pearls
- Shake Atmeksi oral suspension for at least 30 seconds before every dose so each dose has the right amount of medicine.
- Tell your prescriber about liver disease or dialysis, since both slow how quickly your body clears methocarbamol.
- It does not loosen the muscle directly, so keep up the rest, stretching and physical therapy it is meant to support.
- The NSAID boxed warning on this page belongs to a diclofenac combination product, not to methocarbamol on its own.
⚠️ FDA Boxed Warning — the FDA’s strongest safety alert ▾
WARNING: RISK OF SERIOUS CARDIOVASCULAR AND GASTROINTESTINAL EVENTS Cardiovascular Thrombotic Events Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may occur early in treatment and may increase with duration of use (see WARNINGS ). Diclofenac sodium delayed-release tablets are contraindicated in the setting of coronary artery bypass graft (CABG) surgery (s...
Read the full warning on DailyMed →Patient information guide A plain-language walkthrough of Methocarbamol, written from its FDA label.
What Methocarbamol is used for
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Methocarbamol is used for one main purpose across its products.
- Methocarbamol tablets, including Tanlor: an add-on to rest, physical therapy and other measures for discomfort from acute, painful musculoskeletal conditions.
- Methocarbamol injection, including Robaxin (intramuscular or intravenous): the same use.
- Atmeksi oral suspension: the same use, in patients 16 and older.
How Methocarbamol works
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How methocarbamol works in humans has not been established. It may be due to general central nervous system (CNS) depression, and it may be related to its sedative properties.
It does not act directly on the contracting machinery of muscle, the motor end plate or the nerve fiber, and it does not directly relax tense skeletal muscles.
Methocarbamol dosage
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Methocarbamol is taken by mouth as tablets or Atmeksi suspension, or given by injection into a muscle or vein. Oral products are taken several times a day. A higher daily amount is used for the first 48 to 72 hours, then usually lowered.
- Atmeksi: shake for at least 30 seconds before use. Food lowered and delayed absorption in the label's study.
- Injection (including Robaxin): given by a healthcare professional for no more than 3 consecutive days, except in tetanus. A course can be repeated after 48 drug-free hours.
Follow your prescriber's directions and your product's label.
Dosing details from the FDA-approved label
From the Methocarbamol prescribing information (“Dosage and Administration”). Doses are set by your prescriber for your product, condition, kidney function and age — never change a dose on your own.
- Adults, oral tablets (Methocarbamol Tablets, USP, 500 mg)
- Initial dosage: 3 tablets four times daily
- Maintenance dosage: 2 tablets four times daily
- Six grams a day are recommended for the first 48 to 72 hours of treatment
- Thereafter the dosage can usually be reduced to approximately 4 grams a day
- Maximum: For severe conditions 8 grams a day may be administered
- Adults, oral tablets (Methocarbamol Tablets, USP, 750 mg)
- Initial dosage: 2 tablets four times daily
- Maintenance dosage: 1 tablet every 4 hours or 2 tablets three times daily
- Six grams a day are recommended for the first 48 to 72 hours of treatment
- Thereafter approximately 4 grams a day
- Maximum: For severe conditions 8 grams a day may be administered
- Adults, oral suspension (Atmeksi)
- Initial dosage: 1,500 mg (10 mL) 4 times daily
- Maintenance dosage: 750 mg (5 mL) every 4 hours or 1,500 mg (10 mL) 3 times daily
- Six grams a day are recommended for the first 48 to 72 hours
- Thereafter approximately 4 grams a day
- Maximum: For severe conditions 8 grams a day may be administered
- Shake the drug product for at least 30 seconds before administration
- Adults, oral tablets (Tanlor)
- Initial dosage: 1½ tablets 4 times daily
- Maintenance dosage: 1 tablet 4 times daily
- Six grams a day are recommended for the first 48 to 72 hours
- Thereafter approximately 4 grams a day
- Maximum: For severe conditions 8 grams a day may be administered
- Adults, injection: moderate symptoms
- One dose of 1 gram (one 10 mL vial) may be adequate
- Ordinarily need not be repeated, as the oral form will usually sustain the relief
- Maximum: Total adult dosage should not exceed 30 mL (3 vials) a day for more than 3 consecutive days except in tetanus
- If condition persists, a like course may be repeated after a drug-free interval of 48 hours
- Adults, injection: severest cases or postoperative conditions when oral administration is not feasible
- Additional doses of 1 gram may be repeated every 8 hours
- Maximum: 3 g/day for no more than 3 consecutive days
- IV: maximum rate of three mL per minute undiluted; one vial as a single dose not diluted to more than 250 mL; IM: not more than five mL into each gluteal region
- Adults, tetanus (injection)
- Inject one or two vials into the tubing of the indwelling needle
- An additional 10 mL or 20 mL may be added to the infusion bottle for a total of up to 30 mL (three vials) as the initial dose
- Repeat every six hours until a nasogastric tube can be inserted, then crushed tablets in water or saline via the tube
- Maximum: Total daily oral doses up to 24 grams may be required
- Pediatric patients, tetanus (injection)
- Minimum initial dose of 15 mg/kg or 500 mg/m2
- May be repeated every six hours, if required
- Maximum: Total dose should not exceed 1.8 g/m2 for 3 consecutive days
Read the label’s full dosing text
2 DOSAGE AND ADMINISTRATION Adults Initial dosage: 1,500 mg (10 mL) 4 times daily Maintenance dosage: 750 mg (5 mL) every 4 hours or 1,500 mg (10 mL) 3 times daily Six grams a day are recommended for the first 48 to 72 hours of treatment. (For severe conditions 8 grams a day may be administered). Thereafter, the dosage can usually be reduced to approximately 4 grams a day. 2.1 Important Dosage and Administration Instructions Initial dosage: 1,500 mg (10 mL) 4 times daily Maintenance dosage: 750 mg (5 mL) every 4 hours or 1,500 mg (10 mL) 3 times daily Six grams a day are recommended for the first 48 to 72 hours of treatment. (For severe conditions 8 grams a day may be administered). Thereafter, the dosage can usually be reduced to approximately 4 grams a day. Inform the patient to shake the drug product for at least 30 seconds to ensure it is uniform before administration.
2.1 Important Dosage and Administration Instructions Initial dosage: 1,500 mg (10 mL) 4 times daily Maintenance dosage: 750 mg (5 mL) every 4 hours or 1,500 mg (10 mL) 3 times daily Six grams a day are recommended for the first 48 to 72 hours of treatment. (For severe conditions 8 grams a day may be administered). Thereafter, the dosage can usually be reduced to approximately 4 grams a day. Inform the patient to shake the drug product for at least 30 seconds to ensure it is uniform before administration.
Read the full Dosage and Administration section on DailyMed →
Methocarbamol side effects
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Drowsiness, nausea and blurred vision are listed among the symptoms of methocarbamol overdose, so they are worth watching for.
Seek urgent help for breathing problems, seizures, very low blood pressure signs, or being unable to stay awake.
Methocarbamol warnings and precautions
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- Drowsiness and impaired alertness: Atmeksi may affect your ability to drive or use machinery. Wait until you know how it affects you.
- Alcohol and other CNS depressants: Methocarbamol can add to their effects.
- Overdose: Deaths have been reported with methocarbamol alone and with other CNS depressants, including alcohol.
Methocarbamol interactions
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Be careful with anything that slows the brain or nervous system.
- Alcohol: effects can be added together.
- Benzodiazepines: additive sedating effect.
- Opioids: additive sedating effect.
- Tricyclic antidepressants: additive sedating effect, even at recommended doses.
Interactions listed in the FDA-approved label
From the Methocarbamol prescribing information (“Drug Interactions”): what the manufacturer studied or reported to the FDA.
- Anticoagulants (e.g., warfarin), antiplatelet agents, SSRIs, SNRIs: Diclofenac and anticoagulants have a synergistic effect on bleeding, with increased risk of serious bleeding compared with either drug alone. Monitor patients for signs of bleeding.
- Aspirin: Concomitant use does not produce greater therapeutic effect than NSAID alone and significantly increases GI adverse reactions. Not generally recommended because of increased risk of bleeding; diclofenac is not a substitute for low dose aspirin for cardiovascular protection.
- ACE inhibitors, angiotensin receptor blockers, beta-blockers: NSAIDs may diminish the antihypertensive effect; with ACE inhibitors or ARBs in elderly, volume-depleted or renally impaired patients, renal function may deteriorate, including possible acute renal failure. Monitor blood pressure; monitor for worsening renal function in at-risk patients; keep patients adequately hydrated; assess renal function at start and periodically.
- Diuretics (loop and thiazide): NSAIDs reduced the natriuretic effect of loop diuretics (e.g., furosemide) and thiazide diuretics in some patients. Observe for signs of worsening renal function and assure diuretic efficacy including antihypertensive effects.
- Digoxin: Diclofenac has been reported to increase serum digoxin concentration and prolong its half-life. Monitor serum digoxin levels.
- Lithium: NSAIDs have produced elevations in plasma lithium levels and reductions in renal lithium clearance; mean minimum lithium concentration increased 15% and renal clearance decreased by approximately 20%. Monitor patients for signs of lithium toxicity.
- Methotrexate: Concomitant use may increase the risk for methotrexate toxicity (e.g., neutropenia, thrombocytopenia, renal dysfunction). Monitor patients for methotrexate toxicity.
- Cyclosporine: Concomitant use may increase cyclosporine's nephrotoxicity. Monitor patients for signs of worsening renal function.
- Other NSAIDs or salicylates (e.g., diflunisal, salsalate): Concomitant use increases the risk of GI toxicity, with little or no increase in efficacy. Concomitant use is not recommended.
- Pemetrexed: Concomitant use may increase the risk of pemetrexed-associated myelosuppression, renal, and GI toxicity. In patients with creatinine clearance 45 to 79 mL/min, monitor for myelosuppression, renal and GI toxicity; avoid short half-life NSAIDs (e.g., diclofenac) for two days before, the day of, and two days following pemetrexed; for longer half-life NSAIDs interrupt dosing for at least five days before, the day of, and two days following.
Read the label’s full interactions text
Drug Interactions See Table 2 for clinically significant drug interactions with diclofenac. Table 2. Clinically Significant Drug Interactions with Diclofenac Drugs That Interfere with Hemostasis Clinical Impact: Diclofenac and anticoagulants such as warfarin have a synergistic effect on bleeding. The concomitant use of diclofenac and anticoagulants have an increased risk of serious bleeding compared to the use of either drug alone. Serotonin release by platelets plays an important role in hemostasis. Case-control and cohort epidemiological studies showed that concomitant use of drugs that interfere with serotonin reuptake and an NSAID may potentiate the risk of bleeding more than an NSAID alone. Intervention: Monitor patients with concomitant use of diclofenac sodium delayed-release tablets with anticoagulants (e.g., warfarin), antiplatelet agents (e.g., aspirin), selective serotonin reuptake inhibitors (SSRIs), and serotonin norepinephrine reuptake inhibitors (SNRIs) for signs of bleeding (see WARNINGS: Hematologic Toxicity ). Aspirin Clinical Impact: Controlled clinical studies showed that the concomitant use of NSAIDs and analgesic doses of aspirin does not produce any greater therapeutic effect than the use of NSAIDs alone. In a clinical study, the concomitant use of an NSAID and aspirin was associated with a significantly increased incidence of GI adverse reactions as compared to use of the NSAID alone (see WARNINGS: Gastrointestinal Bleeding, Ulceration, and Perforation ). Intervention: Concomitant use of diclofenac sodium delayed-release tablets and analgesic doses of aspirin is not generally recommended because of the increased risk of bleeding (see WARNINGS: Hematologic Toxicity ). Diclofenac sodium delayed-release tablets are not a substitute for low dose aspirin for cardiovascular protection.
Excerpted — the section continues on the label. Read the full Drug Interactions section on DailyMed →
Not a complete list. The label covers the interactions the manufacturer studied or reported, and our own interaction database does not cover every medicine either. Bring your full medication list, including vitamins and herbal products, to your pharmacist.
Before taking Methocarbamol
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- Atmeksi: not shown safe and effective under age 16.
- Liver disease: clearance was reduced about 70% in people with cirrhosis.
- Kidney problems: clearance was reduced about 40% in people on dialysis.
- Older adults: the half-life was slightly longer.
- Pregnancy: limited case-report data did not identify an increased risk of major birth defects or miscarriage.
- Breastfeeding: there are no human data. Weigh the benefits of breastfeeding against your need for the medicine.
Methocarbamol overdose
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Overdose can cause breathing problems, nausea, drowsiness, blurred vision, low blood pressure, seizures, coma and death. Treatment is supportive care, such as monitoring breathing and giving IV fluids. Call Poison Help at 1-800-222-1222.
How your body processes Methocarbamol
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In the Atmeksi study, oral methocarbamol was absorbed quickly, peaking in under an hour. Food lowered the peak level by 51% and total exposure by 31%, and delayed the peak to about 1.6 hours.
The half-life was about 1.3 to 1.5 hours. The body breaks it down by dealkylation and hydroxylation, and essentially all metabolites leave in the urine. Small amounts leave unchanged.
How to store Methocarbamol
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Store at 20º to 25º C (68º to 77º F) .
Written from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →
Supplements & herbs that interact with Methocarbamol
20 supplements and herbal products have documented interactions with Methocarbamol in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.
- Major · 2
- Moderate · 9
- Minor · 9
Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.
Methocarbamol: pharmacist answers to common questions
Quick, plain-English answers to the questions patients ask most about Methocarbamol — the kind of thing our pharmacy team would talk through with you at the counter.
What is methocarbamol for?
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Can I drink alcohol while taking it?
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Can I drive after taking it?
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How should I take it?
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Is it safe in pregnancy or while breastfeeding?
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What if I take too much?
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Is Methocarbamol available over the counter?
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When was Methocarbamol first available?
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Who makes Methocarbamol?
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Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →
More about Methocarbamol on HelloPharmacist
Methocarbamol forms and strengths (how it comes)
Methocarbamol is available in 3 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.
Need a version that does not list lactose, a gluten source, a dye or gelatin? Inactive ingredients differ by manufacturer: see Methocarbamol inactive ingredients by manufacturer.
Tablet
How this form is used
- Tanlor and methocarbamol tablets are used as an add-on to rest, physical therapy and other measures for discomfort from acute, painful musculoskeletal conditions.
- Tanlor and methocarbamol tablets are taken by mouth several times a day.
- The label describes a higher amount for the first 48 to 72 hours, with the daily amount usually reduced afterward.
- Methocarbamol tablets come in 500 mg and 750 mg strengths, and the number of tablets per dose depends on the strength, so follow your own label.
Injection
How this form is used
- Robaxin and methocarbamol injection are used as an add-on to rest, physical therapy and other measures for discomfort from acute, painful musculoskeletal conditions.
- Robaxin and methocarbamol injection are for intravenous and intramuscular use only.
- Robaxin and methocarbamol injection total adult use should not go beyond 3 consecutive days, except in treating tetanus.
- If the condition persists, the label allows a like course to be repeated after a 48-hour drug-free interval.
- With Robaxin and methocarbamol injection, the oral form will usually keep up the relief started by the injection.
Oral suspension
How this form is used
- Atmeksi is used as an add-on to rest, physical therapy and other measures for discomfort from acute, painful musculoskeletal conditions in patients 16 and older.
- Atmeksi should be shaken for at least 30 seconds before each use.
- Atmeksi is taken by mouth several times a day, with a higher amount for the first 48 to 72 hours and usually less afterward.
- Food slowed and reduced absorption of Atmeksi in the label's study.
Methocarbamol on the U.S. market: products, makers and brands
How Methocarbamol appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.
63 companies list 212 Methocarbamol product records with the FDA, mostly as tablet, injection, oral suspension; the earliest marketing or approval year on record is 1957. Brand names on the directory include Robaxin, Tanlor, Atmeksi and 1 more; the rest are generics.
FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.
Also listed with the FDA, not a patient dose form: Powder (17) · Kit (1) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.
Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.
How widely Methocarbamol is used (Medicaid data)
A general measure of how commonly Methocarbamol is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.
Think of this as a proxy for how widely Methocarbamol is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.
How commonly is Methocarbamol prescribed? Of the 1,601 medications we measure, Methocarbamol ranks #97 by Medicaid prescriptions — more than 94% of them.
Utilization by Methocarbamol product
Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.
methocarbamol 500 MG Oral Tablet Most dispensed
Summed across the 15 of 547 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 197943
methocarbamol 750 MG Oral Tablet
Summed across the 14 of 476 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 197944
10 ML methocarbamol 100 MG/ML Injection
Summed across the 11 of 34 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 238175
methocarbamol 1000 MG Oral Tablet
Summed across the 2 of 7 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2611794
Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.
Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Methocarbamol, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 42 of 1,064 listed Methocarbamol NDCs with Medicaid activity.
Compare Methocarbamol products
A representative set of FDA-listed product records for Methocarbamol — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)
| Strength | Route | Manufacturer / Labeler | Category ⓘ | Details |
|---|---|---|---|---|
| 💊Injection | ||||
| 100 mg/mL | Intramuscular, Intravenous | Baxter Healthcare Corporation | ANDA | View NDC → |
| 100 mg/mL | Intramuscular, Intravenous | Dr.Reddys Laboratories Inc., | ANDA | View NDC → |
| 1000 mg/10 mL | Intramuscular, Intravenous | Eugia US LLC | ANDA | View NDC → |
| 100 mg/mL | Intramuscular, Intravenous | Fresenius Kabi USA, LLC | ANDA | View NDC → |
| 100 mg/mL | Intramuscular, Intravenous | Gland Pharma Limited | ANDA | View NDC → |
| 1000 mg/10 mL | Intramuscular, Intravenous | Henry Schein, Inc | ANDA | View NDC → |
| 100 mg/mL | Intramuscular, Intravenous | Hikma Pharmaceuticals USA Inc. × 2 listings | NDA | View NDC → |
| 100 mg/mL | Intramuscular, Intravenous, Intravenous | Jvet Pharmaceuticals Llc | ANDA | View NDC → |
| 100 mg/mL | Intramuscular, Intravenous | Meitheal Pharmaceuticals Inc. | ANDA | View NDC → |
| 100 mg/mL | Intramuscular, Intravenous | Sagent Pharmaceuticals × 2 listings | ANDA | View NDC → |
| 100 mg/mL | Intravenous | Slate Run Pharmaceuticals, LLC | ANDA | View NDC → |
| 100 mg/mL | Intramuscular, Intravenous | Somerset Therapeutics, LLC | ANDA | View NDC → |
| 💊Oral suspension | ||||
| 750 mg/5 mL | Oral | Rosemont Pharmaceuticals LLC | NDA | View NDC → |
| 💊Tablet | ||||
| 500 mg | Oral | A-S Medication Solutions × 11 listings | ANDA | View NDC → |
| 750 mg | Oral | A-S Medication Solutions × 4 listings | ANDA | View NDC → |
| 500 mg | Oral | Advanced Rx of Tennessee, LLC × 3 listings | ANDA | View NDC → |
| 750 mg | Oral | Advanced Rx of Tennessee, LLC × 3 listings | ANDA | View NDC → |
| 500 mg | Oral | Advanced Rx Pharmacy of Tennessee, LLC × 3 listings | ANDA | View NDC → |
| 750 mg | Oral | Advanced Rx Pharmacy of Tennessee, LLC | ANDA | View NDC → |
| 500 mg | Oral | American Health Packaging | ANDA | View NDC → |
| 750 mg | Oral | American Health Packaging | ANDA | View NDC → |
| 500 mg | Oral | Aphena Pharma Solutions - Tennessee, LLC × 2 listings | ANDA | View NDC → |
| 750 mg | Oral | Aphena Pharma Solutions - Tennessee, LLC × 5 listings | ANDA | View NDC → |
| 500 mg | Oral | Asclemed USA, Inc. × 4 listings | ANDA | View NDC → |
| 750 mg | Oral | Asclemed USA, Inc. × 5 listings | ANDA | View NDC → |
| 500 mg | Oral | Asclemed Usa Inc. | ANDA | View NDC → |
| 750 mg | Oral | Asclemed Usa Inc. | ANDA | View NDC → |
| 500 mg | Oral | Aurobindo Pharma Limited | ANDA | View NDC → |
| 750 mg | Oral | Aurobindo Pharma Limited | ANDA | View NDC → |
| 500 mg | Oral | AvPAK | ANDA | View NDC → |
| 750 mg | Oral | AvPAK | ANDA | View NDC → |
| 500 mg | Oral | Bostal LLC | ANDA | View NDC → |
| 750 mg | Oral | Bostal LLC | ANDA | View NDC → |
| 1000 mg | Oral | Bostal LLC | ANDA | View NDC → |
| 500 mg | Oral | Bryant Ranch Prepack × 13 listings | ANDA | View NDC → |
| 750 mg | Oral | Bryant Ranch Prepack | ANDA | View NDC → |
| 500 mg | Oral | Camber Pharmaceuticals, Inc. | ANDA | View NDC → |
| 750 mg | Oral | Camber Pharmaceuticals, Inc. | ANDA | View NDC → |
| 500 mg | Oral | Cardinal Health 107, LLC × 2 listings | ANDA | View NDC → |
| 750 mg | Oral | Cardinal Health 107, LLC × 2 listings | ANDA | View NDC → |
| 500 mg | Oral | Coupler LLC × 2 listings | ANDA | View NDC → |
| 750 mg | Oral | Coupler LLC × 2 listings | ANDA | View NDC → |
| 500 mg | Oral | Direct Rx | ANDA | View NDC → |
| 500 mg | Oral | DirectRx | ANDA | View NDC → |
| 750 mg | Oral | Direct Rx | ANDA | View NDC → |
| 500 mg | Oral | Direct_rx | ANDA | View NDC → |
| 500 mg | Oral | Doc Rx × 2 listings | ANDA | View NDC → |
| 1000 mg | Oral | Fh2 Pharma Llc | ANDA | View NDC → |
| 1000 mg | Oral | Forte Bio-Pharma | ANDA | View NDC → |
| 500 mg | Oral | Gentex Pharma, Llc | ANDA | View NDC → |
| 500 mg | Oral | Golden State Medical Supply, Inc. | ANDA | View NDC → |
| 750 mg | Oral | Golden State Medical Supply, Inc. | ANDA | View NDC → |
| 500 mg | Oral | Granulation Technology, Inc. | ANDA | View NDC → |
| 750 mg | Oral | Granulation Technology, Inc. | ANDA | View NDC → |
| 500 mg | Oral | Granules India Ltd | ANDA | View NDC → |
| 750 mg | Oral | Granules India Ltd | ANDA | View NDC → |
| 500 mg | Oral | Granules Pharmaceuticals Inc. | ANDA | View NDC → |
| 750 mg | Oral | Granules Pharmaceuticals Inc. | ANDA | View NDC → |
| 500 mg | Oral | Hawaii Repack, Inc. × 2 listings | ANDA | View NDC → |
| 750 mg | Oral | Hawaii Repack, Inc. | ANDA | View NDC → |
| 500 mg | Oral | Key Therapeutics | ANDA | View NDC → |
| 750 mg | Oral | Key Therapeutics | ANDA | View NDC → |
| 500 mg | Oral | Major Pharmaceuticals | ANDA | View NDC → |
| 750 mg | Oral | Major Pharmaceuticals | ANDA | View NDC → |
| 500 mg | Oral | Marlex Pharmaceuticals, Inc. | ANDA | View NDC → |
| 750 mg | Oral | Marlex Pharmaceuticals, Inc. | ANDA | View NDC → |
| 500 mg | Oral | Medcore LLC | ANDA | View NDC → |
| 750 mg | Oral | Medcore LLC | ANDA | View NDC → |
| 500 mg | Oral | Medsource Pharmaceuticals | ANDA | View NDC → |
| 1000 mg | Oral | Misemer Pharmaceutical | ANDA | View NDC → |
| 500 mg | Oral | NCS HealthCare of KY, LLC dba Vangard Labs | ANDA | View NDC → |
| 750 mg | Oral | NCS HealthCare of KY, LLC dba Vangard Labs | ANDA | View NDC → |
| 500 mg | Oral | Northwind Health Company, LLC × 2 listings | ANDA | View NDC → |
| 750 mg | Oral | Northwind Health Company, LLC × 2 listings | ANDA | View NDC → |
| 500 mg | Oral | NuCare Pharmaceuticals, Inc. | ANDA | View NDC → |
| 500 mg | Oral | NuCare Pharmaceuticals,Inc. | ANDA | View NDC → |
| 750 mg | Oral | NuCare Pharmaceuticals, Inc. | ANDA | View NDC → |
| 750 mg | Oral | NuCare Pharmaceuticals,Inc. × 3 listings | ANDA | View NDC → |
| 1000 mg | Oral | Oncora Pharma, LLC | ANDA | View NDC → |
| 500 mg | Oral | Oxford Pharmaceuticals, LLC | ANDA | View NDC → |
| 750 mg | Oral | Oxford Pharmaceuticals, LLC | ANDA | View NDC → |
| 500 mg | Oral | PD-Rx Pharmaceuticals, Inc. × 8 listings | ANDA | View NDC → |
| 750 mg | Oral | PD-Rx Pharmaceuticals, Inc. × 6 listings | ANDA | View NDC → |
| 750 mg | Oral | Pharmasource Meds, LLC | ANDA | View NDC → |
| 500 mg | Oral | Phoenix Rx Llc × 2 listings | ANDA | View NDC → |
| 750 mg | Oral | Phoenix Rx Llc × 2 listings | ANDA | View NDC → |
| 500 mg | Oral | Preferred Pharmaceuticals, Inc | ANDA | View NDC → |
| 500 mg | Oral | Preferred Pharmaceuticals Inc. × 4 listings | ANDA | View NDC → |
| 750 mg | Oral | Preferred Pharmaceuticals Inc. × 3 listings | ANDA | View NDC → |
| 500 mg | Oral | Proficient Rx LP × 7 listings | ANDA | View NDC → |
| 750 mg | Oral | Proficient Rx LP × 5 listings | ANDA | View NDC → |
| 500 mg | Oral | Redpharm Drug × 2 listings | ANDA | View NDC → |
| 750 mg | Oral | Redpharm Drug | ANDA | View NDC → |
| 500 mg | Oral | Redpharm Drug, Inc. | ANDA | View NDC → |
| 500 mg | Oral | Remedyrepack Inc. × 2 listings | ANDA | View NDC → |
| 750 mg | Oral | Remedyrepack Inc. × 3 listings | ANDA | View NDC → |
| 500 mg | Oral | Solco Healthcare LLC | ANDA | View NDC → |
| 750 mg | Oral | Solco Healthcare LLC | ANDA | View NDC → |
| 750 mg | Oral | Sportpharm LLC | ANDA | View NDC → |
| 500 mg | Oral | St. Mary's Medical Park Pharmacy × 2 listings | ANDA | View NDC → |
| 750 mg | Oral | St. Mary's Medical Park Pharmacy × 3 listings | ANDA | View NDC → |
| 1000 mg | Oral | Trifluent Pharma LLC | ANDA | View NDC → |
| 500 mg | Oral | Unichem Pharmaceuticals (usa), Inc. | ANDA | View NDC → |
| 750 mg | Oral | Unichem Pharmaceuticals (usa), Inc. | ANDA | View NDC → |
| 500 mg | Oral | Unit Dose Solutions, Inc. × 2 listings | ANDA | View NDC → |
| 500 mg | Oral | XLCare Pharmaceuticals Inc. | ANDA | View NDC → |
| 750 mg | Oral | XLCare Pharmaceuticals Inc. | ANDA | View NDC → |
| 💊Kits | ||||
| — | — | PureTek Corporation | UNAPPROVED DRUG OTHER | View NDC → |
Showing 200 of 212 products — FDA National Drug Code Directory. See every product, package size and price: browse all 212 Methocarbamol NDCs →
Methocarbamol side effects reported to the FDA (FAERS)
After a medicine reaches the market, patients, doctors and drugmakers can send the FDA reports of problems they think may be linked to it. Here’s what’s been reported for Methocarbamol — a signal of what to watch for, not proof the drug caused it.
The effects most often named in FDA reports that mention Methocarbamol are pain, nausea, fatigue; about 62% of the reports were classed as serious. These are voluntary reports, so they show what people report, not how often it happens.
Source: openFDA, from the FDA Adverse Event Reporting System (FAERS). These are voluntary reports — they don’t prove the drug caused the effect, and counts reflect how often something was reported, not how often it actually happens. Reports also often name the very problem the medicine is taken for — a common reason to file one is that the drug didn’t help — so for a pain reliever you may see “pain” high on the list; that points to why the report was filed, not to the drug causing the symptom. This counts every report that lists Methocarbamol in any role, so the total runs higher than the FDA’s official dashboard, which counts only cases where the drug is the suspect. For the authoritative figures, see the FDA FAERS Public Dashboard. Always talk to your pharmacist or doctor.
Methocarbamol FDA approval history
How Methocarbamol went from FDA review to the pharmacy shelf — the key milestones in its regulatory journey.
Methocarbamol was first approved by the FDA in 1957 (Brand: ROBAXIN-750 · Endo Operations); the first generic version was approved in 1974. It remains available in U.S. pharmacies today.
Source: Drugs@FDA.
Methocarbamol recall history
A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.
The FDA’s enforcement reports list 2 Methocarbamol recalls since July 2021. Both are still ongoing or began in the last six months. A recall names specific lots from one company, so check the lot number on your own bottle rather than assuming every product is affected; your pharmacist can check whether your supply came from an affected lot.
- Methocarbamol Injection USP 1,000 mg/10 mL (100 mg/mL), 10 mL Single Dose Vial, Rx Only, Manufactured for: Somerset Therapeutics, LLC, Somerset, NJ 08873, NDC 70069-101-25 (immediate carton) and 7006… Lots: NDC 70069-101-25; A240304, A240305, A240320, A240322, A240334, A240335, A240340, exp. date 05/2026; A240342, A240347, A240385, A240391, exp. date 06/2026; NDC 70069-101-05; A240326, exp. date 05/2026 FDA record D-0354-2025 →
- Methocarbamol Injection, USP 1000mg/10mL, (100mg/mL), 10 mL Single-Dose Vial packed 25 vials per carton, Rx Only, Mfd. in India for: Eugia US LLC. E. Windsor, NJ 08520, NDC 55150-223-10 Lots: Lot #: 3MC23011, Exp 11/30/2026 FDA record D-0440-2024 →
Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Sep 24, 2026.
RxNorm Concept Web — From Ingredient to Every Form and Strength
This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.
RxCUI 6845 3 dose forms · 5 strengths
-
Dose form (SCDF) Injection RxCUI 1740942In current FDA listingsClinical drug / strength (SCD) 10 ML methocarbamol 100 MG/MLRxCUI 238175 -
Dose form (SCDF) Oral Suspension RxCUI 2729334In current FDA listingsClinical drug / strength (SCD) 150 MG/MLRxCUI 2729335 -
Dose form (SCDF) Oral Tablet RxCUI 372831In current FDA listings
Look up RxCUI 6845 in the RxCUI Atlas →
RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.
Methocarbamol supply and shortage status
Whether Methocarbamol is in short supply in the U.S. right now, plus any shortage history the FDA has on record. A shortage usually reflects a manufacturing or demand issue — not a safety problem with the drug.
Source: openFDA, from the FDA Drug Shortages database.
💵 What Methocarbamol costs pharmacies (NADAC benchmark)
The national average invoice price pharmacies pay for the drug itself, from CMS's NADAC survey (data as of Sep 30, 2026). This is a supply-cost benchmark — not a retail price and not what you'd pay at the counter.
| Form | Strength | Pharmacy acquisition benchmark | |
|---|---|---|---|
| Tablet · Oral | 500 mg | $0.039 per tablet | NDC details & price history |
| Tablet · Oral | 750 mg | $0.043 per tablet | NDC details & price history |
| Tablet, Film Coated · Oral | 1000 mg | $8.35 per tablet | NDC details & price history |
Source: CMS National Average Drug Acquisition Cost (NADAC), a survey of retail pharmacy invoice prices. Benchmarks shown are the range across package sizes of a representative product for each form and strength — other manufacturers' products may differ.
Methocarbamol brand names
Methocarbamol is sold under 4 brand names in the FDA directory — Robaxin, Tanlor, Atmeksi, Methocarb 500-EZS. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.
Who makes Methocarbamol: manufacturers and labelers
63 companies list Methocarbamol products with the FDA. By number of product records, the largest are Bryant Ranch Prepack, A-S Medication Solutions, PD-Rx Pharmaceuticals, Inc.. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.
…and 39 more on the FDA NDC directory.
Methocarbamol drug class (RxNorm)
Methocarbamol belongs to the Muscle Relaxant class.
Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.
Sources for this Methocarbamol page
Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.
How this page is built
HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. Rosemont Pharmaceuticals LLC is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →