Perindopril
Generic name: Pronounced as (per in' doe pril)
Medical Content Reviewed By HelloPharmacist Staff
Last Revised - 07/15/2017
On this page
- Why is this medication prescribed?
- How should this medicine be used?
- Other uses for this medicine
- What special precautions should I follow?
- What special dietary instructions should I follow?
- What should I do if I forget a dose?
- What side effects can this medication cause?
- What should I know about STORAGE and DISPOSAL of this medication?
- What should I do in case of OVERDOSE?
- What OTHER INFORMATION should I know?
- Drug interactions
IMPORTANT WARNING
Do not take perindopril if you are pregnant. If you become pregnant while taking perindopril, call your doctor immediately. Perindopril may harm the fetus.
Why is this medication prescribed?
Perindopril is used alone or in combination with other medications to treat high blood pressure. Perindopril is in a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It makes blood flow more smoothly by preventing the production of certain natural chemicals that tighten the blood vessels.
High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys, and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.
How should this medicine be used?
Perindopril comes as a tablet to take by mouth. It is usually taken once or twice a day. To help you remember to take perindopril, take it around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take perindopril exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Your doctor may start you on a low dose of perindopril and gradually increase your dose.
Perindopril controls high blood pressure but does not cure it. Continue to take perindopril even if you feel well. Do not stop taking perindopril without talking to your doctor.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking perindopril,
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tell your doctor and pharmacist if you are allergic to perindopril, angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin, in Lotrel), captopril (Capoten), enalapril (Vasotec, in Vaseretic), fosinopril (Monopril), lisinopril (n Prinzide, in Zestoretic), moexipril (Univasc, in Uniretic), quinapril (Accupril, in Accuretic, in Quinaretic), ramipril (Altace), trandolapril (Mavik, in Tarka), any other medications, or any of the ingredients in perindopril tablets. Ask your pharmacist for a list of the ingredients.
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tell your doctor or pharmacist if you are taking valsartan and sacubitril (Entresto) or if you have stopped taking it within the last 36 hours. Your doctor will probably tell you not to take perindopril, if you are also taking valsartan and sacubitril. Also, tell your doctor if you have diabetes and you are taking aliskiren (Tekturna, in Amturnide, Tekamlo, Tekturna HCT). Your doctor will probably tell you not to take perindopril if you have diabetes and you are also taking aliskiren.
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tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: cyclosporine (Gengraf, Neoral, Sandimmune), diuretics ('water pills'), heparin, indomethacin (Indocin, Tivorbex), lithium (Lithobid), and potassium supplements (K-Dur, Klor-Con, others). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
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tell your doctor if you are on dialysis and if have or have ever had heart failure; lupus (SLE); scleroderma; diabetes; angioedema (swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, and/or lower legs); or kidney or liver disease.
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tell your doctor if you are breastfeeding.
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you should know that diarrhea, vomiting, not drinking enough fluids, and sweating a lot can cause a drop in blood pressure, which may cause lightheadedness and fainting.
What special dietary instructions should I follow?
Talk to your doctor before using salt substitutes containing potassium. If your doctor prescribes a low-salt or low-sodium diet, follow these directions carefully.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
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Perindopril may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
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cough
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headache
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weakness
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dizziness
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diarrhea
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stomach pain
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upset stomach
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Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
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swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
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hoarseness
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difficulty swallowing or breathing
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lightheadedness
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fainting
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fever, sore throat, chills, and other signs of infection
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irregular or rapid heartbeats
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Perindopril may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
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If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I know about STORAGE and DISPOSAL of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
What OTHER INFORMATION should I know?
Keep all appointments with your doctor.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Drug interactions
Drug | Interaction |
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Candesartan | Candesartan The risk or severity of renal failure, hypotension, and hyperkalemia can be increased when Perindopril is combined with Candesartan. |
Cilostazol | Cilostazol Perindopril may decrease the excretion rate of Cilostazol which could result in a higher serum level. |
Estrogen and Progestin (Oral Contraceptives) | Estrogen and Progestin (Oral Contraceptives) The risk or severity of angioedema can be increased when Conjugated estrogens is combined with Perindopril. |
Fenofibrate | Fenofibrate Perindopril may decrease the excretion rate of Fenofibrate which could result in a higher serum level. |
Guanfacine | Guanfacine Perindopril may decrease the excretion rate of Guanfacine which could result in a higher serum level. |
Magnesium Hydroxide | Magnesium Hydroxide Perindopril may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level. |
Methylergonovine | Methylergonovine Methylergometrine may decrease the antihypertensive activities of Perindopril. |
Mycophenolate | Mycophenolate Perindopril may decrease the excretion rate of Mycophenolic acid which could result in a higher serum level. |
Naratriptan | Naratriptan Naratriptan may decrease the antihypertensive activities of Perindopril. |
Olsalazine | Olsalazine The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Olsalazine is combined with Perindopril. |
Paregoric | Paregoric The risk or severity of adverse effects can be increased when Morphine is combined with Perindopril. |
Penbutolol | Penbutolol Perindopril may increase the hypotensive activities of Acebutolol. |
Potassium | Potassium The risk or severity of hyperkalemia can be increased when Potassium is combined with Perindopril. |
Prednisone | Prednisone Prednisone may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Ranitidine | Ranitidine Perindopril may decrease the excretion rate of Ranitidine which could result in a higher serum level. |
Reserpine | Reserpine Reserpine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Rizatriptan | Rizatriptan Perindopril may decrease the excretion rate of Rizatriptan which could result in a higher serum level. |
Sumatriptan | Sumatriptan Sumatriptan may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Tacrolimus | Tacrolimus Tacrolimus may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Tizanidine | Tizanidine The risk or severity of hypotension can be increased when Tizanidine is combined with Perindopril. |
Zolmitriptan | Zolmitriptan Zolmitriptan may decrease the antihypertensive activities of Perindopril. |
Ampicillin Injection | Ampicillin Injection Ampicillin may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Doxycycline Injection | Doxycycline Injection Doxycycline may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Fluconazole Injection | Fluconazole Injection The risk or severity of hyperkalemia can be increased when Fluconazole is combined with Perindopril. |
Foscarnet Injection | Foscarnet Injection Foscarnet may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Hydromorphone Injection | Hydromorphone Injection Hydromorphone may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Levofloxacin Injection | Levofloxacin Injection Perindopril may decrease the excretion rate of Levofloxacin which could result in a higher serum level. |
Meperidine Injection | Meperidine Injection Meperidine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Metoclopramide Injection | Metoclopramide Injection Perindopril may decrease the excretion rate of Metoclopramide which could result in a higher serum level. |
Morphine Injection | Morphine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Perindopril. |
Pamidronate Injection | Pamidronate Injection Pamidronic acid may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Vancomycin Injection | Vancomycin Injection Perindopril may decrease the excretion rate of Vancomycin which could result in a higher serum level. |
Altretamine | Altretamine Amphetamine may increase the hypotensive activities of Perindopril. |
Cefuroxime | Cefuroxime Cefuroxime may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Cyclosporine | Cyclosporine Cyclosporine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Enoxaparin Injection | Enoxaparin Injection The risk or severity of hyperkalemia can be increased when Perindopril is combined with Enoxaparin. |
Torsemide | Torsemide Torasemide may increase the excretion rate of Perindopril which could result in a lower serum level and potentially a reduction in efficacy. |
Olanzapine | Olanzapine The risk or severity of adverse effects can be increased when Olanzapine is combined with Perindopril. |
Eprosartan | Eprosartan The risk or severity of renal failure, hypotension, and hyperkalemia can be increased when Perindopril is combined with Eprosartan. |
Meloxicam | Meloxicam The therapeutic efficacy of Perindopril can be decreased when used in combination with Meloxicam. |
Pantoprazole | Pantoprazole Pantoprazole may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Telmisartan | Telmisartan The risk or severity of renal failure, hypotension, and hyperkalemia can be increased when Perindopril is combined with Telmisartan. |
Temozolomide | Temozolomide Perindopril may decrease the excretion rate of Temozolomide which could result in a higher serum level. |
Zaleplon | Zaleplon Perindopril may decrease the excretion rate of Zaleplon which could result in a higher serum level. |
Linezolid | Linezolid Linezolid may increase the hypotensive activities of Perindopril. |
Trimipramine | Trimipramine Trimipramine may decrease the antihypertensive activities of Perindopril. |
Tenofovir | Tenofovir Tenofovir may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Choline Magnesium Trisalicylate | Choline Magnesium Trisalicylate The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Choline magnesium trisalicylate is combined with Perindopril. |
Sirolimus | Sirolimus The risk or severity of adverse effects can be increased when Perindopril is combined with Sirolimus. |
Dutasteride | Dutasteride Dutasteride may decrease the antihypertensive activities of Perindopril. |
Epinephrine Injection | Epinephrine Injection Epinephrine may decrease the antihypertensive activities of Perindopril. |
Eplerenone | Eplerenone Eplerenone may increase the hyperkalemic activities of Perindopril. |
Olmesartan | Olmesartan The risk or severity of renal failure, hypotension, and hyperkalemia can be increased when Perindopril is combined with Olmesartan. |
Zonisamide | Zonisamide Perindopril may increase the excretion rate of Zonisamide which could result in a lower serum level and potentially a reduction in efficacy. |
Aripiprazole | Aripiprazole The risk or severity of hypotension can be increased when Aripiprazole is combined with Perindopril. |
Atomoxetine | Atomoxetine Atomoxetine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Dexmethylphenidate | Dexmethylphenidate Dexmethylphenidate may decrease the antihypertensive activities of Perindopril. |
Atazanavir | Atazanavir Atazanavir may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Almotriptan | Almotriptan Perindopril may decrease the excretion rate of Almotriptan which could result in a higher serum level. |
Eletriptan | Eletriptan Eletriptan may decrease the antihypertensive activities of Perindopril. |
Vardenafil | Vardenafil Vardenafil may increase the antihypertensive activities of Perindopril. |
Alfuzosin | Alfuzosin Alfuzosin may increase the hypotensive activities of Perindopril. |
Emtricitabine | Emtricitabine Perindopril may decrease the excretion rate of Emtricitabine which could result in a higher serum level. |
Memantine | Memantine Perindopril may decrease the excretion rate of Memantine which could result in a higher serum level. |
Tadalafil | Tadalafil Tadalafil may increase the antihypertensive activities of Perindopril. |
Frovatriptan | Frovatriptan Frovatriptan may decrease the antihypertensive activities of Perindopril. |
Apomorphine Injection | Apomorphine Injection The risk or severity of adverse effects can be increased when Apomorphine is combined with Perindopril. |
Protriptyline | Protriptyline Protriptyline may decrease the antihypertensive activities of Perindopril. |
Duloxetine | Duloxetine The risk or severity of orthostatic hypotension and syncope can be increased when Perindopril is combined with Duloxetine. |
Tinidazole | Tinidazole Perindopril may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
Bosentan | Bosentan Perindopril may increase the hypotensive activities of Bosentan. |
Cefditoren | Cefditoren Cefdinir may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Cyanocobalamin Injection | Cyanocobalamin Injection Hydroxocobalamin may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Eszopiclone | Eszopiclone Eszopiclone may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Ganciclovir | Ganciclovir Perindopril may decrease the excretion rate of Ganciclovir which could result in a higher serum level. |
Ribavirin | Ribavirin Perindopril may decrease the excretion rate of Ribavirin which could result in a higher serum level. |
Solifenacin | Solifenacin Solifenacin may decrease the antihypertensive activities of Perindopril. |
Valganciclovir | Valganciclovir Perindopril may decrease the excretion rate of Valganciclovir which could result in a higher serum level. |
Adefovir | Adefovir Adefovir may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Dextroamphetamine | Dextroamphetamine Amphetamine may increase the hypotensive activities of Perindopril. |
Isocarboxazid | Isocarboxazid Isocarboxazid may increase the hypotensive activities of Perindopril. |
Ramelteon | Ramelteon Perindopril may decrease the excretion rate of Ramelteon which could result in a higher serum level. |
Fentanyl | Fentanyl Fentanyl may decrease the antihypertensive activities of Perindopril. |
Pregabalin | Pregabalin The risk or severity of angioedema can be increased when Pregabalin is combined with Perindopril. |
Phenylephrine | Phenylephrine Phenylephrine may decrease the antihypertensive activities of Perindopril. |
Ranolazine | Ranolazine Ranolazine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Rasagiline | Rasagiline Rasagiline may increase the hypotensive activities of Perindopril. |
Sitagliptin | Sitagliptin The risk or severity of angioedema can be increased when Perindopril is combined with Sitagliptin. |
Varenicline | Varenicline Perindopril may decrease the excretion rate of Varenicline which could result in a higher serum level. |
Albuterol | Albuterol Perindopril may decrease the excretion rate of Salbutamol which could result in a higher serum level. |
Paliperidone | Paliperidone Perindopril may decrease the excretion rate of Paliperidone which could result in a higher serum level. |
Clofarabine Injection | Clofarabine Injection Clofarabine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Lubiprostone | Lubiprostone Perindopril may decrease the excretion rate of Lubiprostone which could result in a higher serum level. |
Rituximab Injection | Rituximab Injection Perindopril may increase the hypotensive activities of Rituximab. |
Aliskiren | Aliskiren The risk or severity of hypotension, hyperkalemia, and nephrotoxicity can be increased when Aliskiren is combined with Perindopril. |
Bismuth Subsalicylate | Bismuth Subsalicylate The risk or severity of renal failure can be increased when Bismuth subsalicylate is combined with Perindopril. |
Pemetrexed Injection | Pemetrexed Injection Perindopril may decrease the excretion rate of Pemetrexed which could result in a higher serum level. |
Lisdexamfetamine | Lisdexamfetamine Lisdexamfetamine may decrease the antihypertensive activities of Perindopril. |
Nabilone | Nabilone The risk or severity of adverse effects can be increased when Nabilone is combined with Perindopril. |
Sorafenib | Sorafenib Sorafenib may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Levocetirizine | Levocetirizine Perindopril may decrease the excretion rate of Levocetirizine which could result in a higher serum level. |
Pegaptanib Injection | Pegaptanib Injection Perindopril may decrease the excretion rate of Pegaptanib which could result in a higher serum level. |
Azacitidine Injection | Azacitidine Injection Perindopril may decrease the excretion rate of Azacitidine which could result in a higher serum level. |
Temsirolimus | Temsirolimus The risk or severity of angioedema can be increased when Perindopril is combined with Temsirolimus. |
Lenalidomide | Lenalidomide Lenalidomide may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Budesonide | Budesonide Perindopril may decrease the excretion rate of Budesonide which could result in a higher serum level. |
Desmopressin | Desmopressin Desmopressin may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Doripenem Injection | Doripenem Injection Perindopril may decrease the excretion rate of Doripenem which could result in a higher serum level. |
Arsenic Trioxide Injection | Arsenic Trioxide Injection Perindopril may decrease the excretion rate of Arsenic trioxide which could result in a higher serum level. |
Desvenlafaxine | Desvenlafaxine Perindopril may decrease the excretion rate of Desvenlafaxine which could result in a higher serum level. |
Cevimeline | Cevimeline Cevimeline may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Nebivolol | Nebivolol Perindopril may increase the hypotensive activities of Nebivolol. |
Tretinoin | Tretinoin The risk or severity of adverse effects can be increased when Tretinoin is combined with Perindopril. |
Certolizumab Injection | Certolizumab Injection Perindopril may decrease the excretion rate of Certolizumab pegol which could result in a higher serum level. |
Daptomycin Injection | Daptomycin Injection Daptomycin may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Methylnaltrexone Injection | Methylnaltrexone Injection Perindopril may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level. |
Midazolam | Midazolam Midazolam may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Dexrazoxane Injection | Dexrazoxane Injection Dexrazoxane may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Milnacipran | Milnacipran Perindopril may decrease the excretion rate of Milnacipran which could result in a higher serum level. |
Plerixafor Injection | Plerixafor Injection Perindopril may decrease the excretion rate of Plerixafor which could result in a higher serum level. |
Sodium Phosphate | Sodium Phosphate The risk or severity of nephrotoxicity can be increased when Perindopril is combined with Sodium phosphate, monobasic. |
Fesoterodine | Fesoterodine Perindopril may decrease the excretion rate of Fesoterodine which could result in a higher serum level. |
Betaxolol | Betaxolol Betaxolol may increase the hypotensive activities of Perindopril. |
Iloperidone | Iloperidone Iloperidone may decrease the antihypertensive activities of Perindopril. |
Prasugrel | Prasugrel Perindopril may decrease the excretion rate of Prasugrel which could result in a higher serum level. |
Everolimus | Everolimus The risk or severity of adverse effects can be increased when Everolimus is combined with Perindopril. |
Tolvaptan (low blood sodium) | Tolvaptan (low blood sodium) Tolvaptan may increase the hyperkalemic activities of Perindopril. |
Dronedarone | Dronedarone Dronedarone may decrease the antihypertensive activities of Perindopril. |
Pralatrexate Injection | Pralatrexate Injection Perindopril may decrease the excretion rate of Pralatrexate which could result in a higher serum level. |
Palonosetron Injection | Palonosetron Injection Palonosetron may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Saxagliptin | Saxagliptin The risk or severity of angioedema can be increased when Perindopril is combined with Saxagliptin. |
Telavancin Injection | Telavancin Injection Perindopril may decrease the excretion rate of Telavancin which could result in a higher serum level. |
Topotecan | Topotecan Perindopril may decrease the excretion rate of Topotecan which could result in a higher serum level. |
Asenapine | Asenapine Asenapine may decrease the antihypertensive activities of Perindopril. |
Dalfampridine | Dalfampridine Perindopril may decrease the excretion rate of Dalfampridine which could result in a higher serum level. |
Ceftaroline Injection | Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Lurasidone | Lurasidone Lurasidone may decrease the antihypertensive activities of Perindopril. |
Acetaminophen Injection | Acetaminophen Injection Acetaminophen may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Vilazodone | Vilazodone Vilazodone may decrease the antihypertensive activities of Perindopril. |
Ipilimumab Injection | Ipilimumab Injection Perindopril may decrease the excretion rate of Ipilimumab which could result in a higher serum level. |
Denileukin Diftitox Injection | Denileukin Diftitox Injection Aldesleukin may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Terbutaline Injection | Terbutaline Injection Perindopril may decrease the excretion rate of Terbutaline which could result in a higher serum level. |
Azilsartan | Azilsartan The risk or severity of renal failure, hypotension, and hyperkalemia can be increased when Perindopril is combined with Azilsartan medoxomil. |
Roflumilast | Roflumilast Perindopril may decrease the excretion rate of Roflumilast which could result in a higher serum level. |
Linagliptin | Linagliptin The risk or severity of angioedema can be increased when Perindopril is combined with Linagliptin. |
Potassium Iodide | Potassium Iodide The risk or severity of hyperkalemia can be increased when Potassium Iodide is combined with Perindopril. |
Rivaroxaban | Rivaroxaban Perindopril may decrease the excretion rate of Rivaroxaban which could result in a higher serum level. |
Ruxolitinib | Ruxolitinib Perindopril may decrease the excretion rate of Ruxolitinib which could result in a higher serum level. |
Clobazam | Clobazam Clobazam may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Deferiprone | Deferiprone Perindopril may decrease the excretion rate of Deferiprone which could result in a higher serum level. |
Cabergoline | Cabergoline Cabergoline may decrease the antihypertensive activities of Perindopril. |
Naloxone Injection | Naloxone Injection Perindopril may decrease the excretion rate of Naloxone which could result in a higher serum level. |
Ambrisentan | Ambrisentan Perindopril may increase the hypotensive activities of Ambrisentan. |
Fondaparinux Injection | Fondaparinux Injection Fondaparinux may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Iloprost | Iloprost Iloprost may increase the hypotensive activities of Perindopril. |
Enzalutamide | Enzalutamide Perindopril may decrease the excretion rate of Enzalutamide which could result in a higher serum level. |
Mirabegron | Mirabegron Mirabegron may decrease the antihypertensive activities of Perindopril. |
Teduglutide Injection | Teduglutide Injection Perindopril may decrease the excretion rate of Teduglutide which could result in a higher serum level. |
Alogliptin | Alogliptin The risk or severity of angioedema can be increased when Perindopril is combined with Alogliptin. |
Pomalidomide | Pomalidomide Perindopril may decrease the excretion rate of Pomalidomide which could result in a higher serum level. |
Canagliflozin | Canagliflozin The risk or severity of renal failure, hypotension, and hyperkalemia can be increased when Perindopril is combined with Canagliflozin. |
Methazolamide | Methazolamide Methazolamide may increase the excretion rate of Perindopril which could result in a lower serum level and potentially a reduction in efficacy. |
Trametinib | Trametinib Perindopril may decrease the excretion rate of Trametinib which could result in a higher serum level. |
Levomilnacipran | Levomilnacipran Perindopril may decrease the excretion rate of Levomilnacipran which could result in a higher serum level. |
Ertapenem Injection | Ertapenem Injection Ertapenem may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Vortioxetine | Vortioxetine Perindopril may decrease the excretion rate of Vortioxetine which could result in a higher serum level. |
Avanafil | Avanafil Avanafil may increase the antihypertensive activities of Perindopril. |
Ketorolac Injection | Ketorolac Injection The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Ketorolac is combined with Perindopril. |
Obinutuzumab Injection | Obinutuzumab Injection Perindopril may increase the hypotensive activities of Obinutuzumab. |
Sofosbuvir | Sofosbuvir Perindopril may decrease the excretion rate of Sofosbuvir which could result in a higher serum level. |
Dapagliflozin | Dapagliflozin The risk or severity of renal failure, hypotension, and hyperkalemia can be increased when Dapagliflozin is combined with Perindopril. |
Apremilast | Apremilast Perindopril may decrease the excretion rate of Apremilast which could result in a higher serum level. |
Droxidopa | Droxidopa Perindopril may decrease the excretion rate of Droxidopa which could result in a higher serum level. |
Iron Dextran Injection | Iron Dextran Injection The risk or severity of adverse effects can be increased when Perindopril is combined with Iron Dextran. |
Testosterone Injection | Testosterone Injection Testosterone may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Empagliflozin | Empagliflozin The risk or severity of renal failure, hypotension, and hyperkalemia can be increased when Empagliflozin is combined with Perindopril. |
Edoxaban | Edoxaban Perindopril may decrease the excretion rate of Edoxaban which could result in a higher serum level. |
Methamphetamine | Methamphetamine Perindopril may decrease the excretion rate of Metamfetamine which could result in a higher serum level. |
Tasimelteon | Tasimelteon Perindopril may decrease the excretion rate of Tasimelteon which could result in a higher serum level. |
Riociguat | Riociguat Perindopril may increase the hypotensive activities of Riociguat. |
Risperidone Injection | Risperidone Injection Perindopril may increase the hypotensive activities of Risperidone. |
Dinutuximab Injection | Dinutuximab Injection The risk or severity of adverse effects can be increased when Dinutuximab is combined with Perindopril. |
Haloperidol Injection | Haloperidol Injection Haloperidol may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Amiloride | Amiloride The risk or severity of hyperkalemia can be increased when Amiloride is combined with Perindopril. |
Macitentan | Macitentan Perindopril may decrease the excretion rate of Macitentan which could result in a higher serum level. |
Flibanserin | Flibanserin Flibanserin may decrease the antihypertensive activities of Perindopril. |
Brexpiprazole | Brexpiprazole Brexpiprazole may decrease the antihypertensive activities of Perindopril. |
Ziprasidone Injection | Ziprasidone Injection Perindopril may increase the antihypertensive activities of Ziprasidone. |
Cariprazine | Cariprazine Cariprazine may decrease the antihypertensive activities of Perindopril. |
Penicillin G Procaine Injection | Penicillin G Procaine Injection Perindopril may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level. |
Ixazomib | Ixazomib Perindopril may decrease the excretion rate of Ixazomib which could result in a higher serum level. |
Lesinurad | Lesinurad Perindopril may decrease the excretion rate of Lesinurad which could result in a higher serum level. |
Amphotericin B Liposomal Injection | Amphotericin B Liposomal Injection Amphotericin B may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Brivaracetam Injection | Brivaracetam Injection Perindopril may decrease the excretion rate of Brivaracetam which could result in a higher serum level. |
Midodrine | Midodrine Midodrine may decrease the antihypertensive activities of Perindopril. |
Selexipag | Selexipag Perindopril may increase the hypotensive activities of Selexipag. |
Furosemide Injection | Furosemide Injection The risk or severity of renal failure and hypotension can be increased when Furosemide is combined with Perindopril. |
Lixisenatide Injection | Lixisenatide Injection Perindopril may decrease the excretion rate of Lixisenatide which could result in a higher serum level. |
Doxepin (Insomnia) | Doxepin (Insomnia) Doxepin may decrease the antihypertensive activities of Perindopril. |
Deutetrabenazine | Deutetrabenazine Perindopril may decrease the excretion rate of Deutetrabenazine which could result in a higher serum level. |
Valbenazine | Valbenazine Perindopril may decrease the excretion rate of Valbenazine which could result in a higher serum level. |
Safinamide | Safinamide Safinamide may increase the hypotensive activities of Perindopril. |
Naldemedine | Naldemedine Perindopril may decrease the excretion rate of Naldemedine which could result in a higher serum level. |
Benznidazole | Benznidazole Perindopril may decrease the excretion rate of Benznidazole which could result in a higher serum level. |
Delafloxacin | Delafloxacin Perindopril may decrease the excretion rate of Delafloxacin which could result in a higher serum level. |
Ertugliflozin | Ertugliflozin The risk or severity of renal failure, hypotension, and hyperkalemia can be increased when Ertugliflozin is combined with Perindopril. |
Apalutamide | Apalutamide Perindopril may decrease the excretion rate of Apalutamide which could result in a higher serum level. |
Fostamatinib | Fostamatinib Fostamatinib may increase the antihypertensive activities of Perindopril. |
Baricitinib | Baricitinib Perindopril may decrease the excretion rate of Baricitinib which could result in a higher serum level. |
Lofexidine | Lofexidine Perindopril may decrease the excretion rate of Lofexidine which could result in a higher serum level. |
Plazomicin Injection | Plazomicin Injection Perindopril may decrease the excretion rate of Plazomicin which could result in a higher serum level. |
Cannabidiol | Cannabidiol Cannabidiol may decrease the antihypertensive activities of Perindopril. |
Stiripentol | Stiripentol Perindopril may decrease the excretion rate of Stiripentol which could result in a higher serum level. |
Paclitaxel (with albumin) Injection | Paclitaxel (with albumin) Injection The risk or severity of adverse effects can be increased when Paclitaxel is combined with Perindopril. |
Prucalopride | Prucalopride Perindopril may decrease the excretion rate of Prucalopride which could result in a higher serum level. |
Siponimod | Siponimod Siponimod may decrease the antihypertensive activities of Perindopril. |
Acyclovir Ophthalmic | Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Solriamfetol | Solriamfetol Perindopril may decrease the excretion rate of Solriamfetol which could result in a higher serum level. |
Pitolisant | Pitolisant Perindopril may decrease the excretion rate of Pitolisant which could result in a higher serum level. |
Selpercatinib | Selpercatinib Selpercatinib may decrease the antihypertensive activities of Perindopril. |
Naxitamab-gqgk Injection | Naxitamab-gqgk Injection Naxitamab may decrease the antihypertensive activities of Perindopril. |
Progestin-Only (drospirenone) Oral Contraceptives | Progestin-Only (drospirenone) Oral Contraceptives Perindopril may increase the hyperkalemic activities of Drospirenone. |
Viloxazine | Viloxazine Perindopril may decrease the excretion rate of Viloxazine which could result in a higher serum level. |
Tobramycin Injection | Tobramycin Injection Tobramycin may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Fenoprofen | Fenoprofen The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Fenoprofen is combined with Perindopril. |
Indomethacin | Indomethacin The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Indomethacin is combined with Perindopril. |
Mefenamic Acid | Mefenamic Acid The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Mefenamic acid is combined with Perindopril. |
Naproxen | Naproxen The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Naproxen is combined with Perindopril. |
Tolmetin | Tolmetin The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Tolmetin is combined with Perindopril. |
Sulindac | Sulindac The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Sulindac is combined with Perindopril. |
Trazodone | Trazodone Trazodone may decrease the antihypertensive activities of Perindopril. |
Isotretinoin | Isotretinoin Perindopril may decrease the excretion rate of Isotretinoin which could result in a higher serum level. |
Sucralfate | Sucralfate Sucralfate may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Floxuridine | Floxuridine Floxuridine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Phenobarbital | Phenobarbital Perindopril may increase the hypotensive activities of Phenobarbital. |
Metaxalone | Metaxalone Metaxalone may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Methotrexate Injection | Methotrexate Injection Methotrexate may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Primidone | Primidone Perindopril may increase the hypotensive activities of Primidone. |
Methsuximide | Methsuximide The risk or severity of hyperkalemia can be increased when Perindopril is combined with Methsuximide. |
Diethylpropion | Diethylpropion Diethylpropion may decrease the antihypertensive activities of Perindopril. |
Chlorpromazine | Chlorpromazine Chlorpromazine may decrease the antihypertensive activities of Perindopril. |
Diazepam | Diazepam Perindopril may decrease the excretion rate of Diazepam which could result in a higher serum level. |
Oxazepam | Oxazepam Perindopril may decrease the excretion rate of Oxazepam which could result in a higher serum level. |
Flurazepam | Flurazepam Flurazepam may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Clorazepate | Clorazepate Clorazepic acid may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Lorazepam | Lorazepam Lorazepam may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Phenoxybenzamine | Phenoxybenzamine Perindopril may decrease the antihypertensive activities of Phenoxybenzamine. |
Carmustine | Carmustine Carmustine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Amantadine | Amantadine Perindopril may decrease the excretion rate of Amantadine which could result in a higher serum level. |
Codeine | Codeine Codeine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Bromocriptine | Bromocriptine Bromocriptine may decrease the antihypertensive activities of Perindopril. |
Metaproterenol | Metaproterenol Orciprenaline may decrease the antihypertensive activities of Perindopril. |
Tranylcypromine | Tranylcypromine Tranylcypromine may increase the hypotensive activities of Perindopril. |
Phenelzine | Phenelzine Phenelzine may increase the hypotensive activities of Perindopril. |
Procarbazine | Procarbazine Procarbazine may increase the hypotensive activities of Perindopril. |
Ergoloid Mesylates | Ergoloid Mesylates Ergoloid mesylate may decrease the antihypertensive activities of Perindopril. |
Tetracycline | Tetracycline Tetracycline may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Thioridazine | Thioridazine Thioridazine may decrease the antihypertensive activities of Perindopril. |
Trifluoperazine | Trifluoperazine Trifluoperazine may decrease the antihypertensive activities of Perindopril. |
Bleomycin | Bleomycin Bleomycin may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Sulfadiazine | Sulfadiazine Sulfadiazine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Methadone | Methadone Methadone may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Benztropine | Benztropine Benzatropine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Maprotiline | Maprotiline Perindopril may decrease the excretion rate of Maprotiline which could result in a higher serum level. |
Ibuprofen | Ibuprofen The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Ibuprofen is combined with Perindopril. |
Azathioprine | Azathioprine The risk or severity of myelosuppression, anemia, and severe leukopenia can be increased when Perindopril is combined with Azathioprine. |
Phentermine | Phentermine Phentermine may decrease the antihypertensive activities of Perindopril. |
Methylphenidate | Methylphenidate Methylphenidate may decrease the antihypertensive activities of Perindopril. |
Amoxapine | Amoxapine Amoxapine may decrease the antihypertensive activities of Perindopril. |
Sulfasalazine | Sulfasalazine The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Sulfasalazine is combined with Perindopril. |
Phenazopyridine | Phenazopyridine Phenazopyridine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Carbamazepine | Carbamazepine Perindopril may decrease the excretion rate of Carbamazepine which could result in a higher serum level. |
Methyldopa | Methyldopa Perindopril may decrease the excretion rate of Methyldopa which could result in a higher serum level. |
Clonidine | Clonidine The risk or severity of hypotension can be increased when Clonidine is combined with Perindopril. |
Prazosin | Prazosin The risk or severity of hypotension can be increased when Prazosin is combined with Perindopril. |
Hydralazine | Hydralazine Perindopril may decrease the excretion rate of Hydralazine which could result in a higher serum level. |
Cimetidine | Cimetidine Cimetidine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Gentamicin Injection | Gentamicin Injection Gentamicin may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Warfarin | Warfarin Perindopril may decrease the excretion rate of Warfarin which could result in a higher serum level. |
Clonazepam | Clonazepam Perindopril may decrease the excretion rate of Clonazepam which could result in a higher serum level. |
Loperamide | Loperamide The risk or severity of hyperkalemia can be increased when Perindopril is combined with Loperamide. |
Promethazine | Promethazine Perindopril may decrease the excretion rate of Promethazine which could result in a higher serum level. |
Meclofenamate | Meclofenamate The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Meclofenamic acid is combined with Perindopril. |
Nitrofurantoin | Nitrofurantoin The risk or severity of hyperkalemia can be increased when Nitrofurantoin is combined with Perindopril. |
Digoxin | Digoxin Perindopril may decrease the excretion rate of Digoxin which could result in a higher serum level. |
Chloroquine | Chloroquine Chloroquine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Quinine | Quinine Quinine may increase the hypotensive activities of Perindopril. |
Ethosuximide | Ethosuximide The risk or severity of hyperkalemia can be increased when Ethosuximide is combined with Perindopril. |
Triamterene | Triamterene The risk or severity of hyperkalemia can be increased when Triamterene is combined with Perindopril. |
Chlorothiazide | Chlorothiazide The therapeutic efficacy of Perindopril can be increased when used in combination with Chlorothiazide. |
Chlorthalidone | Chlorthalidone The risk or severity of hypotension can be increased when Chlorthalidone is combined with Perindopril. |
Metolazone | Metolazone The risk or severity of hypotension can be increased when Metolazone is combined with Perindopril. |
Isosorbide | Isosorbide Isosorbide may increase the excretion rate of Perindopril which could result in a lower serum level and potentially a reduction in efficacy. |
Secobarbital | Secobarbital Perindopril may increase the hypotensive activities of Secobarbital. |
Desipramine | Desipramine Desipramine may decrease the antihypertensive activities of Perindopril. |
Amitriptyline | Amitriptyline Amitriptyline may decrease the antihypertensive activities of Perindopril. |
Imipramine | Imipramine Imipramine may decrease the antihypertensive activities of Perindopril. |
Probenecid | Probenecid Perindopril may decrease the excretion rate of Probenecid which could result in a higher serum level. |
Quinidine | Quinidine Perindopril may decrease the excretion rate of Quinidine which could result in a higher serum level. |
Procainamide | Procainamide Perindopril may decrease the excretion rate of Procainamide which could result in a higher serum level. |
Isoniazid | Isoniazid Perindopril may decrease the excretion rate of Isoniazid which could result in a higher serum level. |
Pyrazinamide | Pyrazinamide Pyrazinamide may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Disopyramide | Disopyramide Disopyramide may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Butabarbital | Butabarbital Perindopril may increase the hypotensive activities of Butabarbital. |
Liothyronine | Liothyronine Liothyronine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Methimazole | Methimazole Methimazole may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Chlorpropamide | Chlorpropamide Chlorpropamide may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Tolbutamide | Tolbutamide Perindopril may decrease the excretion rate of Tolbutamide which could result in a higher serum level. |
Tolazamide | Tolazamide Perindopril may decrease the excretion rate of Tolazamide which could result in a higher serum level. |
Baclofen | Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Perindopril. |
Ethambutol | Ethambutol Ethambutol may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Methyclothiazide | Methyclothiazide The therapeutic efficacy of Perindopril can be increased when used in combination with Methyclothiazide. |
Hydrochlorothiazide | Hydrochlorothiazide The therapeutic efficacy of Perindopril can be increased when used in combination with Hydrochlorothiazide. |
Dantrolene | Dantrolene The risk or severity of hyperkalemia can be increased when Perindopril is combined with Dantrolene. |
Chlorzoxazone | Chlorzoxazone Chlorzoxazone may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Pyridoxine | Pyridoxine Pyridoxine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Folic Acid | Folic Acid Folic acid may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Propranolol (Cardiovascular) | Propranolol (Cardiovascular) Propranolol may increase the hypotensive activities of Perindopril. |
Minoxidil | Minoxidil Minoxidil may increase the hypotensive activities of Perindopril. |
Pseudoephedrine | Pseudoephedrine Pseudoephedrine may decrease the antihypertensive activities of Perindopril. |
Nortriptyline | Nortriptyline Nortriptyline may decrease the antihypertensive activities of Perindopril. |
Spironolactone | Spironolactone The risk or severity of hyperkalemia can be increased when Spironolactone is combined with Perindopril. |
Amphotericin B Injection | Amphotericin B Injection Amphotericin B may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Phytonadione | Phytonadione Perindopril may decrease the excretion rate of Phylloquinone which could result in a higher serum level. |
Amikacin Injection | Amikacin Injection Amikacin may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Nadolol | Nadolol Perindopril may increase the hypotensive activities of Nadolol. |
Allopurinol | Allopurinol The risk of a hypersensitivity reaction to Allopurinol is increased when it is combined with Perindopril. |
Flavoxate | Flavoxate Perindopril may decrease the excretion rate of Flavoxate which could result in a higher serum level. |
Papaverine | Papaverine The risk or severity of adverse effects can be increased when Papaverine is combined with Perindopril. |
Colchicine | Colchicine Perindopril may decrease the excretion rate of Colchicine which could result in a higher serum level. |
Cefaclor | Cefaclor Cefaclor may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Cefadroxil | Cefadroxil Cefadroxil may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Cefazolin Injection | Cefazolin Injection Cefazolin may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Cephalexin | Cephalexin Cephalexin may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Cefoxitin Injection | Cefoxitin Injection Cefoxitin may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Dacarbazine | Dacarbazine Perindopril may decrease the excretion rate of Dacarbazine which could result in a higher serum level. |
Acetazolamide | Acetazolamide Acetazolamide may increase the excretion rate of Perindopril which could result in a lower serum level and potentially a reduction in efficacy. |
Cefotaxime Injection | Cefotaxime Injection Cefotaxime may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Iron Supplements | Iron Supplements The risk or severity of adverse effects can be decreased when Iron is combined with Perindopril. |
Calcitonin Salmon Injection | Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Ketoconazole | Ketoconazole The risk or severity of hyperkalemia can be increased when Perindopril is combined with Ketoconazole. |
Pyrantel | Pyrantel Perindopril may decrease the excretion rate of Pyrantel which could result in a higher serum level. |
Captopril | Captopril The risk or severity of angioedema can be increased when Perindopril is combined with Captopril. |
Dipyridamole | Dipyridamole Dipyridamole may increase the antihypertensive activities of Perindopril. |
Isoxsuprine | Isoxsuprine Isoxsuprine may decrease the antihypertensive activities of Perindopril. |
Ethacrynic Acid | Ethacrynic Acid Etacrynic acid may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Colistimethate Injection | Colistimethate Injection Colistimethate may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Metoprolol | Metoprolol Metoprolol may increase the hypotensive activities of Perindopril. |
Aspirin | Aspirin The therapeutic efficacy of Perindopril can be decreased when used in combination with Acetylsalicylic acid. |
Salsalate | Salsalate The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Salsalate is combined with Perindopril. |
Alprazolam | Alprazolam Alprazolam may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Temazepam | Temazepam Temazepam may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Triazolam | Triazolam Perindopril may decrease the excretion rate of Triazolam which could result in a higher serum level. |
Dicyclomine | Dicyclomine Perindopril may decrease the excretion rate of Dicyclomine which could result in a higher serum level. |
Propantheline | Propantheline Propantheline may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Trimethoprim | Trimethoprim Trimethoprim may increase the hyperkalemic activities of Perindopril. |
Diltiazem | Diltiazem The risk or severity of hyperkalemia can be increased when Diltiazem is combined with Perindopril. |
Nifedipine | Nifedipine The risk or severity of hyperkalemia can be increased when Perindopril is combined with Nifedipine. |
Timolol | Timolol Timolol may increase the hypotensive activities of Perindopril. |
Verapamil | Verapamil Verapamil may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Atenolol | Atenolol Atenolol may increase the hypotensive activities of Perindopril. |
Pindolol | Pindolol Perindopril may increase the hypotensive activities of Pindolol. |
Cisplatin Injection | Cisplatin Injection Perindopril may decrease the excretion rate of Cisplatin which could result in a higher serum level. |
Diflunisal | Diflunisal The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Diflunisal is combined with Perindopril. |
Piroxicam | Piroxicam The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Piroxicam is combined with Perindopril. |
Bumetanide | Bumetanide Bumetanide may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Glipizide | Glipizide Perindopril may decrease the excretion rate of Glipizide which could result in a higher serum level. |
Amoxicillin | Amoxicillin Perindopril may decrease the excretion rate of Amoxicillin which could result in a higher serum level. |
Oxacillin Injection | Oxacillin Injection Oxacillin may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Pentoxifylline | Pentoxifylline Pentoxifylline may increase the hypotensive activities of Perindopril. |
Pentamidine Injection | Pentamidine Injection Pentamidine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Ceftriaxone Injection | Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Labetalol | Labetalol Labetalol may increase the hypotensive activities of Perindopril. |
Auranofin | Auranofin Perindopril may decrease the excretion rate of Auranofin which could result in a higher serum level. |
Leuprolide Injection | Leuprolide Injection Leuprolide may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Gemfibrozil | Gemfibrozil Perindopril may decrease the excretion rate of Gemfibrozil which could result in a higher serum level. |
Guanabenz | Guanabenz Perindopril may decrease the antihypertensive activities of Guanabenz. |
Dipivefrin Ophthalmic | Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Ceftazidime Injection | Ceftazidime Injection Ceftazidime may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Ketoprofen | Ketoprofen The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Ketoprofen is combined with Perindopril. |
Cefotetan Injection | Cefotetan Injection Cefotetan may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Enalapril | Enalapril The risk or severity of angioedema can be increased when Enalapril is combined with Perindopril. |
Flurbiprofen | Flurbiprofen The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Flurbiprofen is combined with Perindopril. |
Amiodarone | Amiodarone The risk or severity of hyperkalemia can be increased when Perindopril is combined with Amiodarone. |
Aztreonam Injection | Aztreonam Injection Aztreonam may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Buspirone | Buspirone Buspirone may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Ciprofloxacin | Ciprofloxacin The risk or severity of hyperkalemia can be increased when Perindopril is combined with Ciprofloxacin. |
Mesalamine | Mesalamine The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Mesalazine is combined with Perindopril. |
Diclofenac | Diclofenac The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Diclofenac is combined with Perindopril. |
Nimodipine | Nimodipine The risk or severity of hyperkalemia can be increased when Nimodipine is combined with Perindopril. |
Clozapine | Clozapine Clozapine may decrease the antihypertensive activities of Perindopril. |
Estazolam | Estazolam Perindopril may decrease the excretion rate of Estazolam which could result in a higher serum level. |
Didanosine | Didanosine Perindopril may decrease the excretion rate of Didanosine which could result in a higher serum level. |
Pentostatin Injection | Pentostatin Injection Pentostatin may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Benazepril | Benazepril The risk or severity of angioedema can be increased when Benazepril is combined with Perindopril. |
Etodolac | Etodolac The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Etodolac is combined with Perindopril. |
Felodipine | Felodipine The risk or severity of hyperkalemia can be increased when Perindopril is combined with Felodipine. |
Fosinopril | Fosinopril The risk or severity of angioedema can be increased when Fosinopril is combined with Perindopril. |
Nabumetone | Nabumetone The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Nabumetone is combined with Perindopril. |
Quinapril | Quinapril The risk or severity of angioedema can be increased when Perindopril is combined with Quinapril. |
Ramipril | Ramipril The risk or severity of angioedema can be increased when Ramipril is combined with Perindopril. |
Epoetin Alfa, Injection | Epoetin Alfa, Injection The serum concentration of Erythropoietin can be decreased when it is combined with Perindopril. |
Itraconazole | Itraconazole The risk or severity of hyperkalemia can be increased when Perindopril is combined with Itraconazole. |
Lisinopril | Lisinopril The risk or severity of angioedema can be increased when Lisinopril is combined with Perindopril. |
Oxaprozin | Oxaprozin The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Oxaprozin is combined with Perindopril. |
Sotalol | Sotalol The risk or severity of adverse effects can be increased when Sotalol is combined with Perindopril. |
Bisoprolol | Bisoprolol Bisoprolol may increase the hypotensive activities of Perindopril. |
Doxazosin | Doxazosin Doxazosin may increase the hypotensive activities of Perindopril. |
Terazosin | Terazosin Perindopril may increase the hypotensive activities of Terazosin. |
Isradipine | Isradipine The risk or severity of hyperkalemia can be increased when Isradipine is combined with Perindopril. |
Venlafaxine | Venlafaxine Venlafaxine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Fluvoxamine | Fluvoxamine Fluvoxamine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Nefazodone | Nefazodone Perindopril may decrease the excretion rate of Nefazodone which could result in a higher serum level. |
Lamotrigine | Lamotrigine The risk or severity of hyperkalemia can be increased when Lamotrigine is combined with Perindopril. |
Losartan | Losartan The risk or severity of renal failure, hypotension, and hyperkalemia can be increased when Perindopril is combined with Losartan. |
Valacyclovir | Valacyclovir Valaciclovir may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Tramadol | Tramadol Tramadol may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Carboplatin Injection | Carboplatin Injection Carboplatin may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Moexipril | Moexipril The risk or severity of angioedema can be increased when Moexipril is combined with Perindopril. |
Ifosfamide Injection | Ifosfamide Injection Perindopril may decrease the excretion rate of Ifosfamide which could result in a higher serum level. |
Nicardipine | Nicardipine Nicardipine may increase the hypotensive activities of Perindopril. |
Bupropion | Bupropion Perindopril may decrease the excretion rate of Bupropion which could result in a higher serum level. |
Ticlopidine | Ticlopidine Ticlopidine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Metformin | Metformin The risk or severity of lactic acidosis can be increased when Perindopril is combined with Metformin. |
Dalteparin Injection | Dalteparin Injection The risk or severity of hyperkalemia can be increased when Perindopril is combined with Dalteparin. |
Nisoldipine | Nisoldipine The risk or severity of hyperkalemia can be increased when Nisoldipine is combined with Perindopril. |
Lamivudine | Lamivudine Lamivudine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Amifostine Injection | Amifostine Injection Perindopril may increase the hypotensive activities of Amifostine. |
Acarbose | Acarbose Acarbose may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Gemcitabine Injection | Gemcitabine Injection Gemcitabine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Cidofovir Injection | Cidofovir Injection Cidofovir may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Meropenem Injection | Meropenem Injection Meropenem may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Clomipramine | Clomipramine Clomipramine may decrease the antihypertensive activities of Perindopril. |
Fosfomycin | Fosfomycin Perindopril may decrease the excretion rate of Fosfomycin which could result in a higher serum level. |
Mirtazapine | Mirtazapine Mirtazapine may decrease the antihypertensive activities of Perindopril. |
Trandolapril | Trandolapril The risk or severity of angioedema can be increased when Trandolapril is combined with Perindopril. |
Topiramate | Topiramate Topiramate may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Valsartan | Valsartan The risk or severity of renal failure, hypotension, and hyperkalemia can be increased when Perindopril is combined with Valsartan. |
Pramipexole | Pramipexole Pramipexole may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Carvedilol | Carvedilol Perindopril may increase the hypotensive activities of Carvedilol. |
Nilutamide | Nilutamide Nilutamide may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Flutamide | Flutamide Flutamide may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Selegiline | Selegiline Selegiline may increase the hypotensive activities of Perindopril. |
Propafenone | Propafenone Propafenone may decrease the antihypertensive activities of Perindopril. |
Irbesartan | Irbesartan The risk or severity of renal failure, hypotension, and hyperkalemia can be increased when Perindopril is combined with Irbesartan. |
Tamsulosin | Tamsulosin Tamsulosin may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Ropinirole | Ropinirole The risk or severity of adverse effects can be increased when Ropinirole is combined with Perindopril. |
Finasteride | Finasteride Finasteride may decrease the antihypertensive activities of Perindopril. |
Quetiapine | Quetiapine Perindopril may increase the hypotensive activities of Quetiapine. |
Cefepime Injection | Cefepime Injection Cefepime may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Cefprozil | Cefprozil Cefprozil may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Cefpodoxime | Cefpodoxime Cefpodoxime may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Cetirizine | Cetirizine Cetirizine may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Tolcapone | Tolcapone Tolcapone may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Capecitabine | Capecitabine Perindopril may decrease the excretion rate of Capecitabine which could result in a higher serum level. |
Abacavir | Abacavir Perindopril may decrease the excretion rate of Abacavir which could result in a higher serum level. |
Sildenafil | Sildenafil Sildenafil may increase the antihypertensive activities of Perindopril. |
Celecoxib | Celecoxib The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Celecoxib is combined with Perindopril. |
Rosiglitazone | Rosiglitazone Rosiglitazone may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Tolterodine | Tolterodine Perindopril may decrease the excretion rate of Tolterodine which could result in a higher serum level. |
Thalidomide | Thalidomide The risk or severity of adverse effects can be increased when Thalidomide is combined with Perindopril. |
Oseltamivir | Oseltamivir Oseltamivir may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Balsalazide | Balsalazide The risk or severity of renal failure, hyperkalemia, and hypertension can be increased when Balsalazide is combined with Perindopril. |
Nateglinide | Nateglinide Nateglinide may decrease the excretion rate of Perindopril which could result in a higher serum level. |
Rabeprazole | Rabeprazole Perindopril may decrease the excretion rate of Rabeprazole which could result in a higher serum level. |
Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists