Drug & supplement interaction

Olive Oil + Salmeterol

Salmeterol brand name: Serevent.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Olive Oil and Salmeterol in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Salmeterol states a food rule worth keeping to.

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Interaction report

Olive Oil and Salmeterol

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Salmeterol and Olive Oil in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Olive Oil safety at a glance

Olive Oil overall Generally safe Olive oil is widely consumed as food and is generally safe in normal dietary amounts.
Pregnancy Likely Safe When olive oil is consumed in amounts commonly found in foods. There is insufficient reliable information available about the safety of olive oil when used in l... Read the full pregnancy detail
Breastfeeding Likely Safe When olive oil is consumed in amounts commonly found in foods. There is insufficient reliable information available about the safety of olive oil when used in l... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Salmeterol and Olive Oil? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Salmeterol

Interactions in our licensed database are recorded against drug classes, not just single drug names. Salmeterol is filed under 3 classifications — beta-adrenergic agonists, qt interval-prolonging drugs, cytochrome p450 3a4 (cyp3a4) substrates. Olive Oil has documented interactions with 1 drug class — the most serious being antihypertensive drugs (moderate) — and none of Salmeterol’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Olive Oil Does Interact With Other Medications

Olive Oil has 172 moderate known drug interactions in our database — Salmeterol isn’t one of them. If you take anything else, check it against the full list below.

Moderate 172 No known interaction 2,658 (incl. Salmeterol)
Taking anything else?

Check Another of Your Medications Against Olive Oil

Covers the 2,830 medications we’ve checked against Olive Oil. Pick one to open its full report.

What to actually watch for

What Olive Oil Itself Has Been Linked To

This is not an interaction — nothing below involves Salmeterol. It is the side-effect record for Olive Oil on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Olive Oil, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • An allergic reaction Worth acting on Additional detail

    “Topically, delayed hypersensitivity and contact dermatitis have been reported after using olive oil.”

    Olive Oil · Natural Medicines adverse-effect record, reported in dermatitis.

    2 sources cited
    1. 289. van Joost T, Smitt JH, van Ketel WG. Sensitization to olive oil (olea europeae). Contact Dermatitis 1981;7:309-10. PubMed
    2. 3275. Isaksson M, Bruze M. Occupational allergic contact dermatitis from olive oil in a masseur. J Am Acad Dermatol 1999;41:312-5. PubMed
  • A skin rash Additional detail

    “Orally and topically, olive oil is well tolerated.

    Most Common Adverse Effects:

    Orally: Nausea.

    Topically: Contact dermatitis.”

    Olive Oil · Natural Medicines adverse-effect record, reported in dermatitis.

  • Nausea Additional detail

    Recorded for Olive Oil in the same Natural Medicines adverse-effect record shown under A skin rash above.

Everything above comes from the Natural Medicines adverse-effect record for Olive Oil — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Salmeterol’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Salmeterol column appears here.

Special populations

Olive Oil in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Safe

When olive oil is consumed in amounts commonly found in foods. There is insufficient reliable information available about the safety of olive oil when used in larger amounts.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

How to take them

Some Salmeterol Products Have a Food Rule — Olive Oil Should Not Break It

At least one FDA label for a product containing Salmeterol says to take it on an empty stomach. Most supplements — Olive Oil included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Salmeterol on its own and move Olive Oil to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Salmeterol products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

One inhalation of SEREVENT DISKUS at least 30 minutes before exercise has been shown to protect patients against EIB.

From the Dosage and Administration section of the FDA label we read for Salmeterol — where that label names a specific product, the instruction is that product's. See the Salmeterol drug page ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

From our Q&A

Questions About Olive Oil or Salmeterol

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Olive Oil or Salmeterol, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Salmeterol

This page covers Olive Oil only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Salmeterol page lists 141 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: American Hellebore (major), Arsenic (major), Cesium (major), Ephedra (major) and Grapefruit (major).

By severity: 7 major · 105 moderate · 29 minor.

From our pharmacist’s overview on the Salmeterol page

“Salmeterol (Serevent) is the long-acting inhaler taken twice daily for asthma or COPD, and its supplement list is one I would approach with real caution. Seven of the 141 ingredients on file rate major: grapefruit can raise salmeterol levels by blocking the enzyme that clears it, St.”

Reviewed by 2 · Jul 18, 2026

Open the Salmeterol interaction page

One more smart check

Taking Olive Oil as Part of a Dietary Supplement Product? Check It for Interactions

We hold 316 real supplement products containing Olive Oil, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Olive Oil. Even though Olive Oil itself has no known interaction with Salmeterol, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Olive Oil and Salmeterol Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Olive Oil
Steady interest

#1,130 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Salmeterol
Top 10%

#261 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Olive Oil reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Olive Oil and Salmeterol records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Olive Oil

What is Olive Oil?

Olive Oil
  • Heart health
  • Cholesterol support
  • General nutrition (Mediterranean diet)
  • Skin and hair care
  • Mild constipation
  • Anti-inflammatory support

Olive oil, especially extra virgin olive oil, is a healthy fat that forms a cornerstone of the Mediterranean diet and is linked with better heart health. Used as part of a balanced diet it is generally safe for most people, but it is calorie-dense, so portion size matters. Talk with your pharmacist or doctor before using concentrated supplements.

Olea europaea · Oleaceae · Oil pressed from the fruit (olives) · Culinary oil (extra virgin, virgin, refined), softgels, capsules, topical oil

An interaction check asks whether these two react with each other — it does not ask whether Olive Oil is a good idea for someone in your situation. Here is what our Olive Oil record says about it on its own.

Olive Oil: dosing

There is no official "dose" of olive oil. In diet studies, people often use a few tablespoons per day as part of their cooking and meals. As a food, the right amount depends on your overall calorie needs.For supplement capsules, there is no proven standardized dose, so follow the product label and do not exceed it. Choosing extra virgin olive oil gives you the most natural plant compounds.

From our Olive Oil monograph — the full record covers uses, side effects and every documented interaction.

Read the full Olive Oil monograph & all interactions
Medication

About Salmeterol Oral Inhalation

What Is Salmeterol Oral Inhalation Used For?

Brand name: Serevent

Serevent Diskus (salmeterol inhalation powder) is used for three main purposes: treating asthma in patients aged 4 and older alongside an inhaled corticosteroid (ICS), preventing exercise-induced bronchospasm (EIB) in patients aged 4 and older, and providing long-term maintenance treatment of bronchospasm associated with COPD — including chronic bronchitis and emphysema — in adults.

Important: Serevent Diskus is not a rescue inhaler. It will not relieve a sudden asthma or COPD attack. For asthma, it must always be used together with an inhaled corticosteroid — using it alone for asthma is contraindicated due to a serious risk of asthma-related death.

See full Salmeterol Oral Inhalation drug information
Keep checking

Other Drugs & Olive Oil

Browse every other medication we’ve checked against Olive Oil — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
172Moderate
0Minor
2,657No known interaction
172 Moderate 2,657 No interaction
Moderate

172 interactions

Showing 60 of 172 moderate interactions — see all 172 on the Olive Oil page.

No interaction 2,657 drugs checked — show the list

We also checked Olive Oil against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,657 medications checked with no known interaction — see the full Olive Oil list.

See the full Olive Oil interactions page
See every supplement checked against Salmeterol, ranked by severity
Evidence & sources

Olive Oil References

The 5 references that drive our Olive Oil monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. van Joost T, Smitt JH, van Ketel WG. Sensitization to olive oil (olea europeae). Contact Dermatitis 1981;7:309-10. PubMed
  2. Trevisan M, Krogh V, Freudenheim J, et al. Consumption of olive oil, butter, and vegetable oils and coronary heart disease risk factors. The Research Group ATS-RF2 of the Italian National Research Council. JAMA 1990;263:688-92. DOI
  3. Keys A, Menotti A, Karvonen MJ , et al. The diet and 15-year death rate in the seven countries study. Am J Epidemiol 1986;124:903-15. PubMed
  4. Isaksson M, Bruze M. Occupational allergic contact dermatitis from olive oil in a masseur. J Am Acad Dermatol 1999;41:312-5. PubMed
  5. Ferrara LA, Raimondi AS, d'Episcopo L, et al. Olive oil and reduced need for antihypertensive medications. Arch Intern Med 2000;160:837-42. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Olive Oil and Salmeterol Together: Common Questions

Is it safe to take Olive Oil with Salmeterol?
We do not list a known interaction between Olive Oil and Salmeterol. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Olive Oil and Salmeterol at the same time of day?
At least one FDA label for a product containing Salmeterol says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Salmeterol on its own and move Olive Oil to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
How was the Olive Oil and Salmeterol combination checked?
Interactions in our licensed database are recorded against drug classes. Salmeterol is filed under 3 classifications, and Olive Oil has documented interactions with 1 drug class — none of Salmeterol's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Olive Oil interact with any other medications?
Yes. Olive Oil has 172 documented drug interactions in our database — Salmeterol is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Salmeterol interact with any supplements?
Yes. Salmeterol has documented interactions with 141 supplements in our database — Olive Oil is not one of them. The Salmeterol interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Olive Oil monograph Uses, safety profile, and every drug interaction in one place Salmeterol Oral Inhalation drug information The full plain-English guide to this medication Salmeterol supplement interactions Every supplement checked against Salmeterol, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 5 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Salmeterol and Olive Oil?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.