Chive Drug Interactions, Uses, Safety & More
What is this page for?
First and foremost: how Chive interacts with medications. The heart of this page is the interaction list — every drug Chive is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Chive is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Chive against your medication
Add one medicationDrugs that interact with Chive
0 medications have a known interaction with Chive, graded by severity. Select any drug for the full evidence-based detail.
We don’t currently list any known drug interactions for Chive. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.
What Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Chive combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Chive: Uses, Safety & Side Effects
Chive is a common kitchen herb in the onion and garlic family that is safe and nutritious when eaten as food. There is little human research supporting it as a medicine, so any health benefits beyond basic nutrition are not well proven. Enjoy it in cooking, and talk to your pharmacist or doctor before using concentrated chive supplements.
- Scientific name
- Allium schoenoprasum
- Family
- Amaryllidaceae
- Part used
- Leaves (and sometimes flowers and bulbs)
- Common forms
- Fresh or dried herb, culinary seasoning, powder, occasional supplement extracts
- Culinary flavoring
- Digestive support
- General immune support
- Antimicrobial
- Source of vitamins and antioxidants
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
Chive is generally safe when eaten in normal food amounts.
There is insufficient reliable information available about the safety of medicinal amounts of chives during pregnancy and breast-feeding; avoid using.
Read the full pregnancy detailThere is insufficient reliable information available about the safety of medicinal amounts of chives during pregnancy and breast-feeding; avoid using.
Read the full breastfeeding detailPregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Chive is a small, grass-like herb in the same plant family as onions and garlic. Its thin, hollow green leaves are widely used to add a mild onion flavor to foods like soups, eggs, potatoes, and salads. The plant also produces pretty purple flowers that are edible too.
Chive grows in many parts of the world, including Europe, Asia, and North America, and is easy to grow in home gardens. Most people use chive simply as a culinary herb rather than as a medicine, though it is sometimes promoted for general health because it contains vitamins, minerals, and plant antioxidants.
Uses & effectiveness
People most commonly use chive as a flavorful, low-calorie food. Traditionally, herbs in the onion and garlic family have been used to support digestion, freshen breath, and provide nutrients. Some people also believe chive may help the immune system or act against germs.
The scientific evidence for chive as a treatment is very limited. Most research on the Allium family has focused on garlic and onion, not chive specifically. Any antimicrobial or antioxidant effects of chive come mainly from laboratory studies, not well-designed human trials. At this time, there is not enough reliable evidence to say chive treats or prevents any disease. Its clearest benefit is as a nutritious part of a healthy diet.
How it works
Like other plants in the onion and garlic family, chive contains sulfur-based compounds that give it its smell and flavor. It also provides vitamin C, vitamin K, folate, and plant pigments called flavonoids and carotenoids, which act as antioxidants.
In laboratory and animal studies, Allium compounds have shown antioxidant and germ-fighting activity. However, these effects are mostly seen in test tubes or animals and may not happen the same way in people eating normal amounts of chive. The proposed mechanisms should be considered preliminary.
Safety & precautions
Chive is widely eaten and is considered safe for most people in the amounts used in cooking. People who are allergic to onion, garlic, leeks, or other plants in the onion family may also react to chive and should be careful.
Pregnancy and breastfeeding: Eating chive as a normal part of food is likely fine. However, the safety of concentrated chive supplements or extracts has not been studied in pregnant or breastfeeding women, so it is best to avoid those higher-dose products unless your doctor approves.
If you have a bleeding disorder, are scheduled for surgery, or take medicines that affect blood, talk to your pharmacist before using large amounts, since onion-family plants may have mild blood-thinning effects.
Side effects
In normal food amounts, chive rarely causes problems. Some people may experience mild digestive upset, gas, or heartburn, especially if they eat a lot. Bad breath or body odor can also occur, similar to garlic and onion.
Allergic reactions are possible but uncommon. Stop using chive and seek medical care if you notice a rash, swelling, itching, or trouble breathing.
Chive: Reported Adverse Effects
Documented safety reports on Chive from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.
Orally, chive is generally well tolerated. Consuming large quantities of chive can lead to dyspepsia.
Topically, chive has been rarely reported to cause contact dermatitis .
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Roller, E., Meller, S., Homey, B., Ruzicka, T., and Neumann, N. J. [Contact dermatitis caused by spinach, hedge mustard and chives]. Hautarzt 2003;54(4):374-375.
Dermatitis Immunologic
Topically, immune-related contact dermatitis associated with chive and other vegetable exposure has been reported in a 54-year-old female vegetable farmer.
Dermatitis Dermatologic
Topically, contact dermatitis related to chive and other vegetable exposure has been reported in a 54-year-old female vegetable farmer.
Dyspepsia Gastrointestinal
Orally, large, unspecified quantities of chive can cause dyspepsia.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
Adverse-effects data: Natural Medicines, Therapeutic Research Center
Dosing
There is no established medicinal dose for chive. It is normally used in whatever amount tastes good in food. Concentrated chive supplements are not common, and standardized dosing has not been determined by research.
If you choose to use a chive supplement, follow the directions on the product label and check with your pharmacist or doctor first, especially if you take other medicines or have a health condition.
Chive & Pregnancy
Chive & Breastfeeding
© 2026 Therapeutic Research Center
Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center
References & further reading
The 3 references that drive our Chive monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Roller, E., Meller, S., Homey, B., Ruzicka, T., and Neumann, N. J. [Contact dermatitis caused by spinach, hedge mustard and chives]. Hautarzt 2003;54(4):374-375.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Brands that make products with Chive
5 brands in our database make a supplement containing Chive.
Supplement products with Chive
23 products in our database contain Chive. Open any to see its full ingredient list and every drug interaction we check.
Chive: Common Questions
Does Chive interact with prescription medications?
How are Chive interactions rated?
Is it safe to take Chive with my medications?
Where does this Chive interaction information come from?
What is Chive used for?
Is Chive safe to eat?
Can I eat Chive while pregnant or breastfeeding?
Does Chive have any nutritional value?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Products that contain Chive
A rotating sample of real supplements in our database that list Chive — open any to see its full ingredients and every drug interaction we check.
- Chive by Hawaii Pharm
- Day 1 and Day 2 NeoLife Detox by NeoLife Nutritionals
- Chive Powder by TerraVita Premium Collection
- Chive by Herbal Terra
- Chive by Herbal Terra
- Chive Non-Alcohol by Hawaii Pharm
- Chive Alcohol Free by Hawaii Pharm
- Chive by Herbal Terra
- Chive 450 mg by TerraVita Premium Collection
- Chive Alcohol Free by Herbal Terra
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