FDA-filed SPL labeling · retrieved through openFDA

Lisinopril

Lisinopril is an ACE inhibitor used to treat high blood pressure, heart failure, and to reduce the risk of death after a heart attack.

Brand names PrinivilQbrelisZestril
Drug class ⓘ Angiotensin Converting Enzyme Inhibitor
Rx Forms 2 Route Oral
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 177 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

At a glance
Linked label effectiveJan 2, 2025
Clinical labels in scope ⓘ177
AvailabilityRx
Earliest approval/marketing year ⓘ1987
FDA-listed product records ⓘ750
Boxed warningYes
How we combine label and product data →
✓No current FDA shortage listed · checked Sep 22, 2026
⭐ Lisinopril at a glance The quick version — the full detail is in the Patient Information Guide below.
💊
HelloPharmacist Editorial Team Bottom Line
Lisinopril is a well-established ACE inhibitor that treats high blood pressure, heart failure, and helps reduce the risk of death after a heart attack. It's generally taken once daily by mouth and works best when taken consistently as prescribed. The most important safety points are to never take it during pregnancy and to call for help immediately if you notice swelling of the face or throat.
How we write & review this content — our editorial policy →
⚠️ FDA Boxed Warning — the FDA’s strongest safety alert ▾

Lisinopril can cause serious harm or death to an unborn baby. If you become pregnant while taking lisinopril, stop taking it as soon as possible and call your doctor right away. Medicines that work on the renin-angiotensin system — the same system lisinopril targets — can damage a baby's kidneys and other developing organs, especially during the second and third trimesters of pregnancy. This can lead to low amniotic fluid, underdeveloped lungs, skeletal problems, kidney failure, low blood pressure in the newborn, and death. If you are of childbearing age, talk to your doctor about effective contraception while using this medicine.

Read the full warning on DailyMed →

📖 Lisinopril: Patient Information Guide

A plain-language walkthrough of Lisinopril — what it treats, how it works, how it’s taken, side effects, warnings and interactions. Tap any section to expand it.

🎯What it's used for▾

Lisinopril is an ACE inhibitor available in several products, each with FDA-approved uses.

  • High blood pressure (hypertension): Zestril tablets, Lisinopril tablets, Lisinoril tablets, and Qbrelis oral solution are all approved to treat high blood pressure in adults and in children 6 years and older. The combination tablet (lisinopril/hydrochlorothiazide, sold as HCTZ) is also approved for high blood pressure.
  • Heart failure (systolic): Zestril, Lisinopril tablets, Lisinoril, and Qbrelis are approved to reduce the signs and symptoms of systolic heart failure, used alongside diuretics and usually digitalis.
  • Reducing risk of death after a heart attack (acute myocardial infarction): Zestril, Lisinopril tablets, Lisinoril, and Qbrelis are approved to reduce mortality in people who are hemodynamically stable within 24 hours of a heart attack.
⚙️How it works▾

Lisinopril blocks ACE — an enzyme that converts a chemical called angiotensin I into angiotensin II, a potent blood vessel constrictor. By stopping this conversion, lisinopril keeps blood vessels relaxed and lowers blood pressure. It also reduces levels of aldosterone, a hormone that causes the body to hold on to sodium and water, which further helps lower blood pressure and reduce strain on the heart.

Lisinopril works in people of all races but tends to produce a smaller blood pressure reduction in Black patients when used alone. Adding a thiazide diuretic (like hydrochlorothiazide) reduces this difference significantly.

💊How it's taken▾

Lisinopril is taken by mouth once a day, and food does not affect how well it is absorbed, so you can take it with or without a meal. It comes as a tablet (Zestril, Lisinopril, Lisinoril, and the combination HCTZ tablet) or as an oral solution (Qbrelis). The dose your doctor prescribes will depend on what condition is being treated, your kidney function, and other medicines you take.

  • For high blood pressure, it is typically taken once daily and the dose may be adjusted based on your blood pressure response.
  • For heart failure, it is usually started at a low dose and gradually increased as tolerated.
  • After a heart attack, it is typically started within 24 hours and continued once daily.

Never adjust your dose or stop taking lisinopril without talking to your doctor first — even if you feel fine.

🤒Side effects — in detail▾

Like all medicines, lisinopril can cause side effects, though many people tolerate it well. The most commonly reported ones include:

  • Dry, persistent cough (one of the most common reasons people switch medicines)
  • Dizziness or lightheadedness, especially when standing up
  • Headache
  • Low blood pressure (hypotension), particularly at the start of treatment
  • Fatigue or weakness
  • Elevated potassium levels (hyperkalemia)
  • Nausea, diarrhea, or upset stomach
  • Minor increases in blood creatinine levels (a kidney marker)

Seek immediate medical attention for swelling of the face, lips, tongue, or throat (angioedema); severe dizziness or fainting; signs of high potassium (muscle weakness); or yellowing of the skin or eyes (jaundice).

⚠️Warnings & precautions▾
  • Fetal harm (Boxed Warning): Lisinopril must not be used during pregnancy — it can cause serious injury or death to an unborn baby. Stop the medicine immediately if you become pregnant and contact your doctor.
  • Angioedema (dangerous swelling): Swelling of the face, tongue, throat, or intestines can occur at any time. This is a medical emergency. Black patients and those taking mTOR inhibitors or neprilysin inhibitors face a higher risk.
  • Low blood pressure (hypotension): Most likely when starting treatment, increasing the dose, or if you are dehydrated or on diuretics. People with heart failure, low sodium, or on dialysis are especially at risk.
  • Kidney function changes: Lisinopril can worsen kidney function, particularly in people with pre-existing kidney disease, renal artery narrowing, or severe heart failure. Kidney labs should be monitored.
  • High potassium (hyperkalemia): Risk increases with kidney disease, diabetes, or when taking potassium-sparing diuretics or potassium supplements. Potassium levels should be checked periodically.
  • Liver problems: Rarely, ACE inhibitors have caused a serious liver reaction progressing from jaundice to liver failure. Stop the medicine and get medical help if jaundice develops.
🔀What it interacts with▾

Lisinopril can interact with several common medicines and supplements — here are the most important ones to know about:

  • Diuretics (water pills): Can cause a steep drop in blood pressure when lisinopril is first started; your doctor may adjust your doses.
  • Potassium-sparing diuretics or potassium supplements: Can raise blood potassium to dangerous levels; close monitoring is needed.
  • NSAIDs (ibuprofen, naproxen, etc.): Can blunt lisinopril's blood pressure effect and increase the risk of kidney problems, especially in older adults or those with kidney disease.
  • Diabetes medicines (insulin or oral agents): Lisinopril may enhance their blood-sugar-lowering effect, increasing the risk of low blood sugar.
  • Lithium: Lisinopril can raise lithium levels in the blood, increasing the risk of lithium toxicity.
  • Gold injections (for rheumatoid arthritis): Nitritoid reactions (flushing, low blood pressure, nausea) have been reported.
  • mTOR inhibitors (sirolimus, everolimus, temsirolimus) or neprilysin inhibitors: Increase the risk of angioedema (dangerous swelling).
  • Other RAS-blocking medicines (ARBs like losartan, or aliskiren): Combining these with lisinopril raises the risk of low blood pressure, high potassium, and kidney failure. Aliskiren must not be used with lisinopril in people with diabetes.

This is not a complete list of interactions. Always talk with your doctor or pharmacist before starting, stopping, or changing any medication.

📋Before taking it▾
  • Do not take lisinopril if you have ever had angioedema (severe swelling) from an ACE inhibitor, or if you have hereditary or idiopathic angioedema.
  • Do not take lisinopril if you are pregnant — it can seriously harm or kill an unborn baby. Use effective contraception and tell your doctor immediately if you become pregnant.
  • Do not breastfeed while taking lisinopril; the potential risk to an infant is not fully known.
  • Tell your doctor if you have kidney disease or are on dialysis — the dose may need to be lowered and kidney function must be monitored closely.
  • Tell your doctor if you have liver disease.
  • Tell your doctor if you have diabetes — interactions with diabetes medicines and potassium levels require monitoring.
  • Lisinopril is not recommended for children under 6 years old or for children with significantly reduced kidney function (GFR below 30 mL/min/1.73 m²).
  • Older adults may be more sensitive to blood pressure drops and kidney effects; careful monitoring is important.
  • If you are scheduled for major surgery or will be under general anesthesia, make sure your surgical team knows you take lisinopril.
  • The combination product lisinopril/hydrochlorothiazide (HCTZ) must not be taken with a neprilysin inhibitor (such as sacubitril) or within 36 hours of switching to or from sacubitril/valsartan.
🚑If you take too much▾

The most likely effect of taking too much lisinopril is a dangerous drop in blood pressure (hypotension), which can cause dizziness, fainting, or worse. If you think you or someone else has taken too much, seek emergency medical help right away. Lisinopril can be removed from the body by hemodialysis.

📡Pharmacodynamics — effects in the body▾

When lisinopril is taken for high blood pressure, it lowers blood pressure in both lying-down and standing positions without causing the heart rate to speed up (compensatory tachycardia). Blood pressure starts to fall within about an hour of taking a dose, with the peak effect occurring around 6 hours after the dose. The blood pressure-lowering effect is maintained with long-term use, and stopping the medicine abruptly does not cause a sharp rebound rise in blood pressure.

🔬Pharmacokinetics — how your body processes it▾

After a dose taken by mouth, lisinopril reaches peak levels in the blood within about 7 hours. Food does not affect how much is absorbed. Lisinopril is not broken down (metabolized) by the body — it passes through unchanged and is eliminated entirely by the kidneys. It has an effective half-life (the time it takes the body to clear half the drug) of about 12 hours, which is why once-daily dosing works. In people with significantly reduced kidney function (GFR below 30 mL/min), the drug clears more slowly and levels build up, so dose adjustments are needed.

📦How to store it▾

Store at 20-25ºC (68-77ºF) . Protect from light, moisture and freezing. Dispense in a tight, light-resistant container as defined in the USP with a child-resistant closure

📄 Written from Lisinopril’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Every point is grounded in that labeling — nothing is invented. How we use AI →

167

Supplements & herbs that interact with Lisinopril

167 supplements and herbal products have documented interactions with Lisinopril in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.

Severity mix
  • Major · 6
  • Moderate · 137
  • Minor · 24
ACTIVATED CHARCOAL Major AMERICAN HELLEBORE Major AMERICAN MISTLETOE Major ASARABACCA Major SIBERIAN COCKLEBUR Major TYRAMINE Major ADRAFINIL Moderate AGMATINE Moderate +159 more
Every supplement checked against Lisinopril — ranked by severity The full interaction hub: 6 major · 137 moderate · 24 minor · every one linked to its full report. Check Lisinopril against your exact supplements

Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.

1

Nutrient depletion considerations

Lisinopril has been associated with lower levels of 1 nutrient in the clinical literature. This does not mean a deficiency will occur — it means these may be worth discussing with your pharmacist or healthcare provider, especially with long-term use.

COENZYME Q10 Insufficient Evidence
See the full Lisinopril nutrient depletion report

Educational information from a licensed clinical database (Natural Medicines) — not medical advice. Do not start or stop medications or supplements without professional guidance.

🩺 Pharmacist Counseling Corner

Quick, plain-English answers to the questions patients ask most about Lisinopril — the kind of thing our pharmacy team would talk through with you at the counter.

What is lisinopril actually used for? ▾
Lisinopril is mainly prescribed to treat high blood pressure — it relaxes your blood vessels so your heart doesn't have to work as hard. It's also used to help manage heart failure and, for some people, to improve survival odds after a heart attack. Your doctor chose it based on what you specifically need.
Can I take lisinopril with food, or does it have to be on an empty stomach? ▾
Good news — food doesn't affect how lisinopril works, so you can take it with or without a meal. What matters most is taking it at roughly the same time each day. Once a day is the typical schedule, but always follow what's on your label.
I've developed a nagging dry cough since starting lisinopril. Is that from the medicine? ▾
Yes, that cough is one of the most well-known side effects of ACE inhibitors like lisinopril. It happens because the medicine also affects a chemical in the lungs called bradykinin. It's not dangerous, but it can be annoying enough that some people switch to a different type of blood pressure medicine. Talk to your doctor — they can help you weigh the options.
What side effects should make me call my doctor right away? ▾
The most urgent one is any swelling of your face, lips, tongue, or throat — this is called angioedema and it can be a medical emergency, so call 911 or go to the ER immediately. Also call your doctor promptly if you feel severely dizzy or faint, notice you're urinating much less than usual, develop yellowing of your skin or eyes, or have severe stomach pain. These could be signs of a serious reaction that needs quick attention.
Is it safe to take lisinopril if I'm pregnant or trying to get pregnant? ▾
No — this is one of the most critical warnings with lisinopril. It can seriously harm or even be fatal to a developing baby, especially during the second and third trimesters. If you find out you're pregnant, stop the medicine as soon as possible and contact your doctor right away. If you're planning a pregnancy, talk to your doctor before you try — they'll work with you to find a safer alternative.
Are there any common medicines or supplements I should avoid while taking lisinopril? ▾
Yes, a few important ones. Over-the-counter pain relievers like ibuprofen or naproxen (NSAIDs) can weaken lisinopril's effect and put extra stress on your kidneys — use acetaminophen for pain if possible. Potassium supplements or salt substitutes containing potassium can raise your potassium to a dangerous level when combined with lisinopril. And if you take water pills (diuretics), diabetes medicines, or lithium, your doctor will want to monitor you more closely because lisinopril can interact with all of these. Always tell every doctor and pharmacist what you're taking.
Is Lisinopril available over the counter? ▾
Lisinopril is dispensed by prescription according to its FDA labeling, so it isn't sold over the counter. Your prescriber and pharmacist will determine if it's appropriate for you.
When was Lisinopril first available? ▾
Lisinopril has been available in the United States since at least 1987, based on FDA approval history (Drugs@FDA) and product marketing records.
Who makes Lisinopril? ▾
Lisinopril is supplied by 70 manufacturers listed in the FDA NDC Directory, including A-S Medication Solutions, Remedyrepack Inc., PD-Rx Pharmaceuticals, Inc..

💬 Answers drafted from Lisinopril’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Grounded in that labeling — nothing is made up. How we use AI →

🧰 Keep exploring

📊Lisinopril supplement interactions167 checked — ranked by severity 🌿Drug & Supplement CheckerLisinopril vs. vitamins & herbs 💬Ask a PharmacistFree answer, usually < 24h 🔎NDC & pricing lookupFind Lisinopril NDCs & costs 🅰️Browse Drugs A–ZLook up any medication

💊 How Lisinopril comes

Lisinopril is available in 2 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Tablet

By mouth
Brands Zestril
How this form is used
What it may be used for
  • Zestril tablets are indicated for high blood pressure in adults and children 6 years and older, heart failure, and to reduce mortality after a heart attack
  • Lisinopril tablets are indicated for high blood pressure in adults and children 6 years and older, heart failure, and to reduce mortality after a heart attack
  • Lisinoril tablets are indicated for high blood pressure in adults and children 6 years and older, heart failure, and to reduce mortality after a heart attack
  • HCTZ (lisinopril and hydrochlorothiazide) tablets are indicated for the treatment of high blood pressure
Important instructions
  • Zestril tablets are taken by mouth once daily; food does not affect absorption
  • Lisinopril tablets are taken by mouth once daily; food does not affect absorption
  • Lisinoril tablets are taken by mouth once daily; food does not affect absorption
  • HCTZ (lisinopril and hydrochlorothiazide) tablets are taken by mouth; follow your prescriber's instructions for timing
Available strengths 6 strengths
2.5 mg 5 mg 10 mg 20 mg 30 mg 40 mg
738 FDA-listed product records ⓘ

Oral solution

By mouth
Brands Qbrelis
How this form is used
What it may be used for
  • Qbrelis oral solution is indicated for high blood pressure in adults and children 6 years and older
  • Qbrelis oral solution is indicated as adjunct therapy for heart failure
  • Qbrelis oral solution is indicated to reduce mortality in hemodynamically stable patients within 24 hours of a heart attack
Important instructions
  • Qbrelis oral solution is taken by mouth once daily
  • Qbrelis can be taken with or without food
  • Qbrelis may be used alone or with other blood pressure medicines as directed by your prescriber
Available strengths 1 strength
1 mg/mL
3 FDA-listed product records ⓘ

📊 Lisinopril across the U.S. market

How Lisinopril appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

2
Dose forms ⓘ
70
Manufacturers
4
Brand names
750
FDA-listed product records ⓘ
1987
First marketed ⓘ

FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

Also listed with the FDA, not a patient dose form: Powder (9) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

A-S Medication Solutions7%
Remedyrepack Inc.7%
PD-Rx Pharmaceuticals, Inc.6%
Bryant Ranch Prepack6%
NuCare Pharmaceuticals,Inc.5%
Legacy Pharmaceutical Packaging, LLC5%
Other makers64%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

📈 How widely Lisinopril is used

A general measure of how commonly Lisinopril is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Lisinopril is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

6,788,371
Medicaid prescriptions filled (Q1–Q4 2025)
$71M gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Lisinopril prescribed? Of the 1,596 medications we measure, Lisinopril ranks #22 by Medicaid prescriptions — more than 99% of them.

Where Lisinopril ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5
Total prescriptions — #22 of 1,596
#17 Ergocalciferol 7,906,448 Rx #18 Trazodone 7,898,849 Rx #19 Levothyroxine 7,786,593 Rx #20 Acetaminophen 7,225,940 Rx #21 Buprenorphine / Naloxo... 6,982,290 Rx #22 Lisinopril 6,788,371 Rx #23 Famotidine 6,721,162 Rx #24 Bupropion 6,669,702 Rx #25 Fluoxetine 6,471,546 Rx #26 Escitalopram 6,377,287 Rx #27 Aspirin 6,339,210 Rx

Utilization by Lisinopril product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

The 10 mg oral tablet is the most-dispensed Lisinopril product — about 28% of these Medicaid prescriptions.

lisinopril 10 MG Oral Tablet Most dispensed

1,912,806 Medicaid prescriptions (Q1–Q4 2025) 28% of Lisinopril prescriptions shown $17.5M gross reimbursement (before rebates) ≈ $9.16 per prescription (gross)

Summed across the 23 of 291 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 314076

lisinopril 20 MG Oral Tablet

1,837,222 Medicaid prescriptions (Q1–Q4 2025) 27% of Lisinopril prescriptions shown $17.7M gross reimbursement (before rebates) ≈ $9.64 per prescription (gross)

Summed across the 24 of 298 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 314077

lisinopril 40 MG Oral Tablet

1,328,497 Medicaid prescriptions (Q1–Q4 2025) 20% of Lisinopril prescriptions shown $14.4M gross reimbursement (before rebates) ≈ $11 per prescription (gross)

Summed across the 24 of 239 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 197884

lisinopril 5 MG Oral Tablet

1,013,378 Medicaid prescriptions (Q1–Q4 2025) 15% of Lisinopril prescriptions shown $9.2M gross reimbursement (before rebates) ≈ $9.03 per prescription (gross)

Summed across the 23 of 234 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 311354

lisinopril 2.5 MG Oral Tablet

479,281 Medicaid prescriptions (Q1–Q4 2025) 7% of Lisinopril prescriptions shown $4M gross reimbursement (before rebates) ≈ $8.30 per prescription (gross)

Summed across the 17 of 164 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 311353

lisinopril 30 MG Oral Tablet

208,883 Medicaid prescriptions (Q1–Q4 2025) 3% of Lisinopril prescriptions shown $2.1M gross reimbursement (before rebates) ≈ $9.93 per prescription (gross)

Summed across the 14 of 107 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 205326

lisinopril 1 MG/ML Oral Solution

8,304 Medicaid prescriptions (Q1–Q4 2025) <1% of Lisinopril prescriptions shown $6.2M gross reimbursement (before rebates) ≈ $746 per prescription (gross)

Summed across the 1 of 1 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1806884

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Lisinopril, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 126 of 1,334 listed Lisinopril NDCs with Medicaid activity.

🔍 Compare Lisinopril products

A representative set of FDA-listed product records for Lisinopril — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Showing 200 of 750 products — FDA National Drug Code Directory. See every product, package size and price: browse all 750 Lisinopril NDCs →

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Lisinopril RxCUI 29046 2 dose forms · 7 strengths
  1. Dose form (SCDF) Oral Solution RxCUI 1806883 In current FDA listings
    Clinical drug / strength (SCD) 1 MG/ML RxCUI 1806884
  2. Dose form (SCDF) Oral Tablet RxCUI 372614 In current FDA listings
    Clinical drug / strength (SCD) 2.5 MG RxCUI 311353 5 MG RxCUI 311354 10 MG RxCUI 314076 20 MG RxCUI 314077 30 MG RxCUI 205326 40 MG RxCUI 197884

Look up RxCUI 29046 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

🏷️ Sold under these brand names

Prinivil Qbrelis Zestril

🏭 Manufacturers & labelers

A-S Medication Solutions 48 Remedyrepack Inc. 47 PD-Rx Pharmaceuticals, Inc. 41 Bryant Ranch Prepack 37 NuCare Pharmaceuticals,Inc. 36 Legacy Pharmaceutical Packaging, LLC 30 Aurobindo Pharma Limited 30 Aphena Pharma Solutions - Tennessee, LLC 27 Lupin Pharmaceuticals, Inc. 24 Proficient Rx LP 21 QPharma Inc 19 Solco healthcare U.S., LLC 18 Actavis Pharma, Inc. 18 American Health Packaging 16 NCS HealthCare of KY, LLC dba Vangard Labs 16 St. Mary's Medical Park Pharmacy 15 Preferred Pharmaceuticals Inc. 14 Northwind Pharmaceuticals 14 Chartwell RX, LLC 12 Almatica Pharma LLC 12 Yiling Pharmaceutical, Inc. 12 Northwind Health Company, LLC 12 Camber Pharmaceuticals, Inc. 12 Exelan Pharmaceuticals, Inc 12

…and 16 more on the FDA NDC directory.

RxNorm drug class

Lisinopril belongs to the Angiotensin Converting Enzyme Inhibitor class.

Pharmacologic class Angiotensin Converting Enzyme Inhibitor
Drug family (ATC) ACE inhibitors, plain
How it works Angiotensin-converting Enzyme Inhibitors

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

🔬 Where this comes from

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Jan 2, 2025
🏭
Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Lisinopril.
📈
Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
🚨
Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Lisinopril after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
177
NDC products indexed
750
Distinct labelers/manufacturers represented
70
Linked representative label ⓘ
Upsher-Smith Laboratories, LLC
Linked label effective
Jan 2, 2025
Composite sections available
25
Linked SPL Set ID
838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8
Linked SPL Document ID
7875efff-59e3-4f68-84c5-e3c9c16d6a3c
Open the linked representative label on DailyMed ↗

How we combine label and product data

HelloPharmacist combines public FDA and NLM records; we don’t author the underlying clinical facts. We identified 177 FDA-filed SPL label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. The representative label is the starting point for the displayed reference monograph; the 12 largest stored in-scope SPL records, which may include that representative, are compared section by section, and the longest available version of each section is retained. Forms, routes, brands, labelers, product-listed strengths, and product-record counts are aggregated separately from ingredient-matched FDA NDC Directory records; package records listed above are associated with the linked SPL; and the normalized concept hierarchy comes from NLM RxNorm.

For canonical ingredient pages, bounded product-attributed indication and administration excerpts may be added to the AI evidence, and the generator is instructed to preserve available product, brand, route, and form qualifiers instead of treating one label as universal. Where a section is identified as AI-written, its plain-language text is generated from bounded label evidence. New draft drug pages remain in the admin review queue before first publication. Upsher-Smith Laboratories, LLC is the representative DailyMed label linked for verification and dates; it is not the sole source used for the page.

This is general education, not medical advice — always consult your doctor or pharmacist about your medications and any medical condition. For the exact wording of the linked representative label, view that label on DailyMed; some displayed composite sections may come from other in-scope SPL labels. Learn how we use AI and our data sources & update cadence.