Phenethylamine (pea) - Efudex (Fluorouracil) Interaction
Herbal: Phenethylamine (pea)
Also Known As: 2-Phenylethanamine, Methylphenylethylamine, PEA
Drug: Fluorouracil
Brand names:
Efudex, Tolak
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Apr 13, 2024
Interaction Details
There were no interactions found between Fluorouracil and Phenethylamine (pea). This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Phenethylamine (pea) Overview
Phenethylamine (PEA) is a monoamine alkaloid present in various sources, including plants, bacteria, fungi, and animals, including humans. It is also found in certain foods like chocolate and eggs. This compound is synthesized in the body through the decarboxylation of the amino acid L-phenylalanine. Within the central nervous system, PEA serves as both a neuromodulator and neurotransmitter, playing a crucial role in neuronal signaling. Phenethylamine is available as a dietary supplement and is used for potential cognitive and mood-enhancing effects, although further research is needed to fully understand its effects in these regards.
Fluorouracil Overview
-
Fluorouracil is generally used in combination with other medications to treat colon cancer or rectal cancer (cancer that begins in the large intestine) that has gotten worse or spread to other parts of the body. Fluorouracil is used in combination with other medications to treat certain types of breast cancer after surgery to remove the tumor or radiation therapy. Fluorouracil is also used to treat cancer of the pancreas and stomach cancer. Fluorouracil is in a class of medications called antimetabolites. It works by slowing or stopping the growth of cancer cells in your body.
Phenethylamine (pea) - More Interactions
Phenethylamine (pea) interacts with 184 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
Return to the main herbal interaction checker page
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
Ask A Pharmacist About Your Herbal Questions!
Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
Ask A Pharmacist