Pumpkin - Cotellic (Cobimetinib Fumarate) Interaction
Herbal: Pumpkin
Also Known As: Cucurbita pepo, Calabaza, Citrouille, Cucurbitea Peponis Semen, Field Pumpkin, Graine de Citrouille, Great Pumpkin, Huile de Graines de Citrouille, Pepo, Pumpkin Seed Oil, Styrian Pumpkin
Drug: Cobimetinib Fumarate
Brand names:
Cotellic
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Apr 13, 2024
Interaction Details
There were no interactions found between Cobimetinib Fumarate and Pumpkin. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Pumpkin Overview
Pumpkin is a type of squash native to North America. Pumpkin is a good source of nutrients, including vitamin A, vitamin C, potassium, and fiber. It is also a rich source of antioxidants, particularly beta-carotene, which is converted to vitamin A in the body.
Pumpkin has been used historically as a dietary supplement for supporting eye health, boosting the immune system, reducing the symptoms of benign prostatic hyperplasia, and helping to reduce the risk of certain types of cancer. Pumpkin is also a good source of fiber, which can help improve digestion and lower cholesterol levels.
Both pumpkin and pumpkin seed extracts have been utilized for dietary supplement purposes.
Cobimetinib Fumarate Overview
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Cobimetinib is used along with vemurafenib (Zelboraf) to treat certain types of melanoma (a type of skin cancer) that cannot be treated with surgery or that has spread to other parts of the body. Cobimetinib is also used to treat histiocytic neoplasms (conditions that cause an overproduction and accumulation of a type of white blood cell in parts of the body). Cobimetinib is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps slow or stop the spread of cancer cells.
Pumpkin - More Interactions
Pumpkin interacts with 1 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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