Pyruvate - Iclusig (Ponatinib) Interaction

Herbal: Pyruvate
Also Known As: 2-Oxopropanoate

Drug: Ponatinib
Brand names: Iclusig

Medical Content Editor
Last updated Apr 13, 2024

Interaction Details

There were no interactions found between Ponatinib and Pyruvate. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.

Still looking for more information about combining Ponatinib and Pyruvate? Ask Dr. Brian Staiger about it by contacting him directly.

Pyruvate Overview

Pyruvate, also known as alpha-ketocarboxylic acid, is an organic acid containing three carbon atoms. Within the body, it is produced through glycolysis, a metabolic pathway that converts glucose into pyruvate. Pyruvate plays a crucial role in the cellular energy production process. It can either be further broken down in the presence of oxygen to produce more energy through aerobic respiration or be converted into lactate in the absence of oxygen during anaerobic respiration, making it an essential molecule for sustaining cellular metabolism.
See More Information Regarding Pyruvate

Ponatinib Overview

  • Ponatinib is used to treat certain types of chronic myeloid leukemia (CML; a type of cancer of the white blood cells), including treatment in people who can no longer benefit from other medications for CML or who cannot take these medications because of side effects. Ponatinib is also used to treat certain types of acute lymphoblastic leukemia (ALL; a type of cancer of the white blood cells) in people who can no longer benefit from other medications for leukemia or who cannot take these medications because of side effects. Ponatinib is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps stop the spread of cancer cells.

See More Information Regarding Ponatinib

Pyruvate - More Interactions

Pyruvate interacts with 0 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown No interactions have been reported or no interaction data is currently available.

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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Drug descriptions are provided by MedlinePlus.

Dr. Brian Staiger, PharmD

Ask A Pharmacist About Your Herbal Questions!

Dr. Brian Staiger, PharmD

In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!

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