Securinega Suffruticosa - Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine Interaction Details

Interaction Details

Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine is classified as belonging to the following category: Stimulant Drugs

Theoretically, taking Securinega suffruticosa with stimulant drugs might increase the risk of serious adverse effects.
Securinega suffruticosa contains the alkaloid securinine. Animal research shows that securinine has CNS stimulating effects.

Interaction Rating

Moderate

Likelihood of Occurrence

Possible

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists

References

Holmes M, Crater AK, Dhudshia B, Thadani AN, Ananvoranich S. Toxoplasma gondii: inhibitory activity and encystation effect of securinine and pyrrolidine derivatives on Toxoplasma growth. Exp Parasitol. 2011;127(2):370-5.
Raj D, Luczkiewicz M. Securinega suffruticosa. Fitoterapia. 2008;79(6):419-27.

Securinega Suffruticosa - More Interactions

Securinega Suffruticosa interacts with 171 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.

Major	The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur.
Moderate	Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur.
Minor	Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction.
Unknown	No interactions have been reported or no interaction data is currently available.