Ciprofloxacin Interactions
Ciprofloxacin is used to treat or prevent certain infections caused by bacteria such as pneumonia; gonorrhea (a sexually transmitted disease); typhoid fever (a serious infection that is common in developing countries); infectious diarrhea (infections that cause severe diarrhea); and infections of the skin, bone, joint, abdomen (stomach area), and prostate (male reproductive gland), Ciprofloxacin is also used to treat or prevent plague (a serious infection that may be spread on purpose as part of a bioterror attack) and inhalation anthrax (a serious infection that may be spread by anthrax germs in the air on purpose as part of a bioterror attack). Ciprofloxacin may also be used to treat bronchitis, sinus infections, or urinary tract infections but should not be used for bronchitis and sinus infections, or certain types of urinary tract infections if there are other treatment options. Ciprofloxacin extended-release (long-acting) tablets are used to treat kidney and urinary tract infections; however, some types of urinary tract infections should only be treated with ciprofloxacin extended release tablets if no other treatment options are available. Ciprofloxacin is in a class of antibiotics called fluoroquinolones. It works by killing bacteria that cause infections.
Antibiotics such as ciprofloxacin will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.
Brand Names Associated with Ciprofloxacin
- Cipro® Oral Suspension
- Cipro® Tablets
- Cipro® XR Extended-release Tablets
- Ciprofloxacin
- Proquin® XR Extended-release Tablets
Have a question about an interaction not listed below?
Ask our clinical pharmacists directly!
Reach out to usClick the drug name (listed by the generic name) to view specific drug-drug interaction details.
- Contraindicated
- Major
- Prednisone
- Metformin
- Warfarin
- Empagliflozin
- Azithromycin
- Sertraline
- Quetiapine
- Clarithromycin
- Ubrogepant
- Dulaglutide
- Simvastatin
- Escitalopram
- Hydrocodone
- Bupropion
- Trazodone
- Fluoxetine
- Duloxetine
- Citalopram
- Tramadol
- Alprazolam
- Cyclobenzaprine
- Venlafaxine
- Zolpidem
- Glipizide
- Oxycodone
- Hydroxyzine
- Insulin Lispro, Recombinant
- Sitagliptin
- Insulin Aspart, Recombinant
- Amitriptyline
- Paroxetine
- Ondansetron
- Glimepiride
- Mirtazapine
- Donepezil
- Methotrexate
- Hydroxychloroquine
- Acalabrutinib
- Acarbose
- Acecainide
- Adagrasib
- Albiglutide
- Alfentanil
- Alfuzosin
- Alogliptin
- Alosetron
- Amiodarone
- Amisulpride
- Amoxapine
- Anagrelide
- Apomorphine
- Aprepitant
- Aripiprazole
- Aripiprazole Lauroxil
- Arsenic Trioxide
- Artemether
- Asenapine
- Astemizole
- Atazanavir
- Avapritinib
- Azimilide
- Bendamustine
- Benzhydrocodone
- Betamethasone
- Bosutinib
- Bretylium
- Brigatinib
- Budesonide
- Buserelin
- Canagliflozin
- Ceritinib
- Chlorpromazine
- Chlorpropamide
- Cholera Vaccine, Live
- Cilostazol
- Clofazimine
- Clomipramine
- Clothiapine
- Clozapine
- Codeine
- Colchicine
- Corticotropin
- Cortisone
- Cosyntropin
- Crizotinib
- Dabrafenib
- Dapagliflozin
- Daridorexant
- Dasatinib
- Deflazacort
- Degarelix
- Delamanid
- Desipramine
- Deslorelin
- Deutetrabenazine
- Dexamethasone
- Dexmedetomidine
- Dihydrocodeine
- Disopyramide
- Dofetilide
- Dolasetron
- Domperidone
- Doxorubicin
- Doxorubicin Hydrochloride Liposome
- Droperidol
- Efavirenz
- Elacestrant
- Elexacaftor
- Encorafenib
- Entrectinib
- Erlotinib
- Ertugliflozin
- Erythromycin
- Etrasimod
- Exenatide
- Fenfluramine
- Fentanyl
- Fexinidazole
- Finerenone
- Fingolimod
- Flecainide
- Fluconazole
- Fludrocortisone
- Fluocortolone
- Formoterol
- Fosaprepitant
- Foscarnet
- Fostemsavir
- Gatifloxacin
- Gemifloxacin
- Gepirone
- Glasdegib
- Glyburide
- Gonadorelin
- Goserelin
- Granisetron
- Halofantrine
- Haloperidol
- Histrelin
- Hydrocortisone
- Ibrutinib
- Ibutilide
- Ifosfamide
- Iloperidone
- Imipramine
- Indomethacin
- Infigratinib
- Inotuzumab Ozogamicin
- Insulin
- Insulin Bovine
- Insulin Degludec
- Insulin Detemir
- Insulin Glulisine
- Ivacaftor
- Ivosidenib
- Ketoconazole
- Lapatinib
- Larotrectinib
- Lefamulin
- Leflunomide
- Lemborexant
- Lenvatinib
- Leuprolide
- Levofloxacin
- Linagliptin
- Liraglutide
- Lixisenatide
- Lofexidine
- Lopinavir
- Lumateperone
- Lumefantrine
- Lurasidone
- Lurbinectedin
- Macimorelin
- Magnesium Sulfate
- Mavacamten
- Mefloquine
- Meperidine
- Methadone
- Methylprednisolone
- Metronidazole
- Midazolam
- Mifepristone
- Miglitol
- Mitapivat
- Mobocertinib
- Moricizine
- Moxifloxacin
- Mycophenolate Mofetil
- Nafarelin
- Naloxegol
- Nateglinide
- Nilotinib
- Nitisinone
- Norfloxacin
- Nortriptyline
- Octreotide
- Ofloxacin
- Olanzapine
- Olaparib
- Omaveloxolone
- Osilodrostat
- Osimertinib
- Oxaliplatin
- Ozanimod
- Pacritinib
- Paliperidone
- Palovarotene
- Panobinostat
- Pasireotide
- Pazopanib
- Pemigatinib
- Pentazocine
- Pexidartinib
- Phenobarbital
- Pimavanserin
- Pioglitazone
- Pirfenidone
- Pitolisant
- Pomalidomide
- Ponesimod
- Porfimer
- Posaconazole
- Pralsetinib
- Pramlintide
- Prednisolone
- Primidone
- Procainamide
- Prochlorperazine
- Promethazine
- Propafenone
- Protriptyline
- Quinidine
- Quinine
- Quizartinib
- Ranolazine
- Rasagiline
- Relugolix
- Repaglinide
- Ribociclib
- Rimegepant
- Rosiglitazone
- Saxagliptin
- Selpercatinib
- Selumetinib
- Semaglutide
- Sematilide
- Sevoflurane
- Simeprevir
- Siponimod
- Sirolimus Protein-Bound
- Sodium Phosphate
- Sodium Phosphate, Dibasic
- Sodium Phosphate, Monobasic
- Solifenacin
- Sonidegib
- Sorafenib
- Sotalol
- Sparsentan
- Sufentanil
- Sulpiride
- Sunitinib
- Tacrolimus
- Tasimelteon
- Tazemetostat
- Tedisamil
- Telavancin
- Telithromycin
- Teriflunomide
- Tetrabenazine
- Tezacaftor
- Theophylline
- Tolazamide
- Tolbutamide
- Tolvaptan
- Toremifene
- Triamcinolone
- Triclabendazole
- Trifluoperazine
- Trimipramine
- Triptorelin
- Vandetanib
- Vardenafil
- Vemurafenib
- Venetoclax
- Vilanterol
- Vinflunine
- Voclosporin
- Voglibose
- Voriconazole
- Zanubrutinib
- Zuclopenthixol
- Moderate
- Levothyroxine
- Amlodipine
- Suvorexant
- Sildenafil
- Diclofenac
- Propranolol
- Abemaciclib
- Aceclofenac
- Aluminum Carbonate, Basic
- Aluminum Hydroxide
- Aluminum Phosphate
- Aminolevulinic Acid
- Avanafil
- Azlocillin
- Calcium
- Minor
Return To Drug Interaction Homepage
What Do The Severity Ratings Mean?
Contraindicated
These drugs, generally, should not be used together simultaneously due to the high risk of severe adverse effects. Combining these medications can lead to dangerous health outcomes and should be strictly avoided unless otherwise instructed by your provider.
Major
This interaction could result in very serious and potentially life-threatening consequences. If you are taking this drug combination, it is very important to be under close medical supervision to minimize severe side effects and ensure your safety. It may be necessary to change a medication or dosage to prevent harm.
Moderate
This interaction has the potential to worsen your medical condition or alter the effectiveness of your treatment. It's important that you are monitored closely and you potentially may need to make adjustments in your treatment plan or drug dosage to maintain optimal health.
Minor
While this interaction is unlikely to cause significant problems, it could intensify side effects or reduce the effectiveness of one or both medications. Monitoring for changes in symptoms and your condition is recommended, and adjustments may be made if needed to manage any increased or more pronounced side effects.
Disclaimer: The information provided on this page is for informational purposes only and should not be considered medical advice. Always consult with a qualified healthcare professional regarding your specific circumstances and medical conditions.
Drug interaction information is compilated from several drug compendia, including:
- Gold Standard Drug Database
- Micromedix
- Lexicomp
- PubMed
The information posted is fact-checked by HelloPharmacist clinicians and reviewed quarterly.