Metoprolol

Major

Metoprolol Sertraline Explained Increased CYP2D6 substrate exposure Details Metoprolol Albuterol Oral Inhalation Accuneb® Explained Reduced efficacy of albuterol Details Metoprolol Abiraterone Abirtega Increased CYP2D6 substrate exposure and an increased risk of CYP2D6 substrate-related adverse effects Details Metoprolol Clonidine Transdermal Patch Catapres An increased risk of worsen sinus node dysfunction and atrioventricular node conduction, an increased risk of bradycardia and AV b... Details Metoprolol Indacaterol Oral Inhalation Arcapta® Decreased efficacy of indacaterol Details Metoprolol Lacosamide Injection Motpoly An increased risk of AV block, bradycardia, and ventricular tachyarrhythmia Details Metoprolol Methylergonovine Methergine An increased risk of enhanced vasoconstrictive Details Metoprolol Olodaterol Oral Inhalation Striverdi Reduced olodaterol exposure and reduced beta-adrenergic blockers exposure Details

Moderate

Metoprolol Acarbose Prandase® Explained Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Metoprolol Asenapine Transdermal Patch Secuado An increased risk of hypotension Details Metoprolol Aspirin Acuprin® Reduced antihypertensive effect Details Metoprolol Aspirin Rectal Aspirin Reduced antihypertensive effect Details Metoprolol Alfuzosin UroXatral An exaggerated hypotensive response to the first dose of the alpha blocker Details Metoprolol Alogliptin Nesina Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Metoprolol Bromfenac Ophthalmic Bromday® Reduced antihypertensive effect Details Metoprolol Canagliflozin Invokana Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Metoprolol Dapagliflozin Farxiga Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Metoprolol Diclofenac Ophthalmic Voltaren® Eye Drops Reduced antihypertensive effect Details Metoprolol Diclofenac Topical (Actinic Keratosis) Pennsaid Reduced antihypertensive effect Details Metoprolol Diclofenac Topical (Arthritis Pain) Pennsaid® Reduced antihypertensive effect Details Metoprolol Diclofenac Transdermal Patch Flector Reduced antihypertensive effect Details Metoprolol Digoxin Cardoxin® Increased risk of bradycardia and possible digitalis glycoside toxicity Details Metoprolol Doxazosin Cardura An exaggerated hypotensive response to the first dose of the alpha blocker Details Metoprolol Dulaglutide Injection Trulicity Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Metoprolol Empagliflozin Glyxambi® (as a combination product containing Empagliflozin and Linagliptin) Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Metoprolol Ertugliflozin Steglatro Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Metoprolol Etodolac Lodine Reduced antihypertensive effect Details Metoprolol Exenatide Injection Bydureon Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Metoprolol Fenoprofen Fenopron Reduced antihypertensive effect Details Metoprolol Flurbiprofen Ansaid Reduced antihypertensive effect Details Metoprolol Flurbiprofen Ophthalmic Ocufen Reduced antihypertensive effect Details Metoprolol Glimepiride Amaryl Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Metoprolol Glipizide Glucotrol Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Metoprolol Glucagon Injection Baqsimi A transient increase in pulse and blood pressure Details Metoprolol Glucagon Injection / Solution Baqsimi A transient increase in pulse and blood pressure Details Metoprolol Glucagon Nasal Powder Baqsimi A transient increase in pulse and blood pressure Details Metoprolol Hydralazine Apresoline® Increased metoprolol concentrations Details Metoprolol Ibuprofen Addaprin Reduced antihypertensive effect Details Metoprolol Insulin Degludec (Rdna Origin) Injection Ryzodeg® (as a combination product containing Insulin Degludec and Insulin Aspart) Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Metoprolol Insulin Detemir (Rdna Origin) Injection Levemir Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details