Drug & supplement interaction

5-deca Zol + Pimecrolimus

Pimecrolimus brand name: Elidel.

No Known Interaction
The bottom line No known interaction

We found no known interaction between 5-deca Zol and Pimecrolimus in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

5-deca Zol and Pimecrolimus

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Pimecrolimus and 5-deca Zol in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for 5-deca Zol at all — not against Pimecrolimus, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

5-deca Zol safety at a glance

5-deca Zol overall Avoid It is an illegal anabolic steroid linked to serious health risks.
Pregnancy Possibly Unsafe When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced ferti... Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced ferti... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Pimecrolimus and 5-deca Zol? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Pimecrolimus’s Own FDA Label Lists

This is not an interaction — none of it involves 5-deca Zol. These are the most notable effects listed in the ADVERSE REACTIONS section of Pimecrolimus’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 2 of them are worth acting on rather than waiting out — marked below.

  • Hives Worth acting on
  • A higher chance of infection Worth acting on
  • A skin rash mentioned in 22.9% of FDA reports for Pimecrolimus
  • A stuffy or runny nose
  • Sore throat
  • Cough
  • Fever
  • Headache

From the ADVERSE REACTIONS section of the FDA label for Pimecrolimus. Read the label on DailyMed › Where a percentage is shown, it is the share of 1,600 voluntary FDA FAERS reports for Pimecrolimus that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. 5-deca Zol’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no 5-deca Zol side to compare — that is a limit of the record, not a statement that 5-deca Zol has no side effects.

Special populations

5-deca Zol in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced fertility, hair loss, acne, and behavioral changes. Anabolic androgenic steroid use has also been associated with hepatotoxicity and increased risk for heart disease. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing anabolic steroids are dangerous. Avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Pimecrolimus

This page covers 5-deca Zol only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Pimecrolimus page lists 3 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Dimethylsulfoxide (dmso) (moderate), Turpentine Oil (moderate) and Alchemilla (minor).

By severity: 2 moderate · 1 minor.

From our pharmacist’s overview on the Pimecrolimus page

“Pimecrolimus (Elidel) is an eczema cream, applied to the skin rather than swallowed, so its supplement interactions are few and they follow one pattern. All three ingredients on file are also used topically, and the two rated moderate, DMSO and turpentine oil, may pull more of the drug through the skin, amplifying both its benefit and…”

Reviewed by 2 · Jul 18, 2026

Open the Pimecrolimus interaction page

How much people look this up

Where 5-deca Zol and Pimecrolimus Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement 5-deca Zol
Steady interest

#1,202 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Pimecrolimus
Top half

#1,263 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every 5-deca Zol reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The 5-deca Zol and Pimecrolimus records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About 5-deca Zol

What is 5-deca Zol?

  • Muscle building and bodybuilding
  • Athletic performance
  • Boosting testosterone
  • Exercise recovery
  • Weight and fat loss
  • Sexual function

5-deca Zol is a synthetic anabolic-androgenic steroid, not a true dietary supplement or herb, and it is illegal to add to supplements in the United States under the Designer Anabolic Steroid Control Act. It is banned by anti-doping authorities and can cause serious hormonal, liver, and heart problems. We strongly recommend avoiding it and talking to your doctor or pharmacist about safe, legal options.

Not applicable (synthetic compound) · Oral capsules or tablets, injectable solutions (often sold illegally)

An interaction check asks whether these two react with each other — it does not ask whether 5-deca Zol is a good idea for someone in your situation. Here is what our 5-deca Zol record says about it on its own.

5-deca Zol: dosing

There is no established, safe, or approved dose for 5-deca Zol. It is not a recognized medicine or legal supplement ingredient, so no health authority provides recommended amounts.Because products containing it are illegal and unregulated, the actual contents and strength are unknown and unreliable. We do not provide dosing guidance for it.

From our 5-deca Zol monograph — the full record covers uses, side effects and every documented interaction.

Read the full 5-deca Zol monograph & all interactions
Medication

About Pimecrolimus Topical

What Is Pimecrolimus Topical Used For?

Brand name: Elidel

Pimecrolimus cream 1% is used to treat mild to moderate atopic dermatitis (eczema) in adults and children aged 2 and older. It is a second-line option — meaning it's tried when other topical prescription treatments haven't worked well enough, or when those treatments aren't a good fit.

It is intended for short-term and non-continuous use only, applied only to the affected areas. It is not approved for use in children under 2 years of age, and it should only be used in people with healthy immune systems.

Most-Reported Side Effects for Pimecrolimus

From FAERS, the FDA’s public side-effect reporting system (1,704 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Dermatitis atopic 200 reports
Pruritus 193 reports
Rash 183 reports
Dry skin 101 reports
Eczema 97 reports
See full Pimecrolimus Topical drug information
Keep checking

Other Drugs & 5-deca Zol

Browse every other medication we’ve checked against 5-deca Zol — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

5-deca Zol References

The 1 references that drive our 5-deca Zol monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking 5-deca Zol and Pimecrolimus Together: Common Questions

Is it safe to take 5-deca Zol with Pimecrolimus?
We do not list a known interaction between 5-deca Zol and Pimecrolimus. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Pimecrolimus interact with any supplements?
Yes. Pimecrolimus has documented interactions with 3 supplements in our database — 5-deca Zol is not one of them. The Pimecrolimus interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Pimecrolimus and 5-deca Zol?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.