Ambrette - Xigduo XR (Dapagliflozin Propanediol, Metformin) Interaction
Herbal: Ambrette
Also Known As: Abelmoschus moschatus, Abelmosco, Abelmosk, Ambretta, Egyptian Alcee, Gandapura, Hibisco, Kasturidana, Kasturilatika, Kasturi Bhendi, Latakasthuri, Latakasturi, Lata Kasturi, Lathakasthuri, Mushkdana, Muskadana, Muskmallow, Okra
Drug: Dapagliflozin Propanediol, Metformin
Brand names:
Xigduo XR
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 04, 2025
Interaction Details
Dapagliflozin Propanediol, Metformin is classified as belonging to the following category: Antidiabetes Drugs
Theoretically, concomitant use of ambrette with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that myricetin, a constituent of ambrette, can lower blood glucose levels.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Liu, I. M., Liou, S. S., Lan, T. W., Hsu, F. L., and Cheng, J. T. Myricetin as the active principle of Abelmoschus moschatus to lower plasma glucose in streptozotocin-induced diabetic rats. Planta Med. 2005;71(7):617-621.
- Liu, I. M., Liou, S. S., and Cheng, J. T. Mediation of beta-endorphin by myricetin to lower plasma glucose in streptozotocin-induced diabetic rats. J.Ethnopharmacol. 3-8-2006;104(1-2):199-206.
- Liu, I. M., Tzeng, T. F., Liou, S. S., and Lan, T. W. Improvement of insulin sensitivity in obese Zucker rats by myricetin extracted from Abelmoschus moschatus. Planta Med. 2007;73(10):1054-1060.
- Liu IM, Tzeng TF, Liou SS. Abelmoschus moschatus (Malvaceae), an aromatic plant, suitable for medical or food uses to improve insulin sensitivity. Phytother Res 2010;24(2):233-9.
Ambrette Overview
Ambrette is a perennial plant native to India, and is known for its fragrant, musky-scented seeds. The oil from ambrette seeds is used in perfumes and colognes, as well as to flavor food. It has a distinctive scent, described as a floral-musky aroma. Ambrette seeds have also been used to treat a variety of conditions in traditional medicine, including respiratory problems, digestive issues, and skin irritation.
Ambrette - More Interactions
Ambrette interacts with 84 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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