Arenaria Rubra - Contrave (Bupropion, Naltrexone) Interaction
Herbal: Arenaria Rubra
Also Known As: Spergularia rubra, Arenaria Roja, Casse-Pierre, Common Sandspurry, Purple Sandwort, Red Sand-spurrey, Sabline Rouge, Sand-spurrey, Sandwort, Spergulaire Rouge, Spergule Rouge
Drug: Bupropion, Naltrexone
Brand names:
Contrave
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jun 22, 2025
Interaction Details
There were no interactions found between Bupropion, Naltrexone and Arenaria Rubra. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Arenaria Rubra Overview
Arenaria rubra, or sandwort, is a low-growing herb found in North America, Europe, Russia, Asia, and Australia. Its above-ground parts are used medicinally and contain triterpene saponins, resins, phenolic compounds (including C-glycosyl flavones), organic acids (oxalic, citric, malic, quinic, fumaric), and fatty acids (azelaic, myristic, palmitic, linoleic, linolenic, stearic). Studies suggest it inhibits alpha-glucosidase, impacting carbohydrate digestion, and has antioxidant effects against superoxide, nitric oxide, and DPPH free radicals. It also inhibits acetylcholinesterase and butyrylcholinesterase, potentially useful in Alzheimer's treatment by increasing acetylcholine availability for brain receptors.
Bupropion, Naltrexone Overview
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The combination of naltrexone and bupropion is used along with a reduced calorie diet and exercise plan to help adults who are obese, or who are overweight and have weight-related medical problems, to lose weight and then to keep from gaining back that weight. Naltrexone is in a class of medications called opiate antagonists. Bupropion is in a class of medications called antidepressants. These medications work together on two areas of the brain, the hunger center and the reward system, to reduce appetite and help control cravings.
Arenaria Rubra - More Interactions
Arenaria Rubra interacts with 16 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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