Artemisia Herba-alba - Starlix (Nateglinide) Interaction
Herbal: Artemisia Herba-alba
Also Known As: AHAE, AHE, Artemisia, Chih, Common Wormwood, Common Worm Wood, Desert Wormwood, Herba Alba, Shih, Thym des Steppes
Drug: Nateglinide
Brand names:
Starlix
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 18, 2025
Interaction Details
Nateglinide is classified as belonging to the following category: Antidiabetes Drugs
Theoretically, concomitant use with antidiabetes drugs might increase the risk of hypoglycemia.
Low quality research shows that Artemisia herba-alba lowers blood glucose.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Marrif HI, Ali BH, Hassan KM. Some pharmacological studies on Artemisia herba-alba (Asso.) in rabbits and mice. J Ethnopharmacol 1995;49:51-5.
- al-Shamaony L, al-Khazraji SM, Twaij HA. Hypoglycaemic effect of Artemisia herba alba. II. Effect of a valuable extract on some blood parameters in diabetic animals. J Ethnopharmacol 1994;43:167-71.
- al-Khazraji SM, al-Shamaony LA, Twaij HA. Hypoglycaemic effect of Artemisia herba alba. I. Effect of different parts and influence of the solvent on hypoglycaemic activity. J Ethnopharmacol 1993;40:163-6.
- Twaij HA, Al-Badr AA. Hypoglycemic activity of Artemisia herba alba. J Ethnopharmacol 1988;24:123-6.
Artemisia Herba-alba Overview
Artemisia herba-alba is a small shrub native to Northern Africa and the Middle East. Its aerial parts, bark, and roots are most often used in traditional medicine. The plant contains compounds like santonin, herbolides, and phenolic compounds, including hydroquinone and quercetin. Santonin is believed to have anthelmintic properties, while the essential oil from its aerial parts shows antibacterial effects against certain bacteria. Some extracts may affect blood glucose levels, with conflicting reports on whether they increase or decrease levels. Additionally, extracts demonstrate antioxidant activity and are used orally for various conditions, including cough, gastrointestinal issues, diabetes, and parasitic infections.
Nateglinide Overview
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Nateglinide is used alone or in combination with other medications to treat type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood) in people whose diabetes cannot be controlled by diet and exercise alone. Nateglinide belongs to a class of drugs called meglitinides. Nateglinide helps your body regulate the amount of glucose (sugar) in your blood. It decreases the amount of glucose by stimulating the pancreas to release insulin.
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Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Taking medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numb, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes.
Artemisia Herba-alba - More Interactions
Artemisia Herba-alba interacts with 84 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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