Babassu - Pradaxa (dabigatran) Interaction
Herbal: Babassu
Also Known As: Attalea speciosa, Babaçu, Babassou, Babassu Coconut, Babassu Palm Tree, Babussupalme, Cusí, Cusi Palm
Drug: dabigatran
Brand names:
Pradaxa, Pradax
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jun 22, 2025
Interaction Details
dabigatran is classified as belonging to the following category: Anticoagulant/Antiplatelet Drugs
Evidence from animal research suggests that babassu has antithrombotic effects. Theoretically, babassu might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs. Some anticoagulant or antiplatelet drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Azevedo, A. P., Farias, J. C., Costa, G. C., Ferreira, S. C., Aragao-Filho, W. C., Sousa, P. R., Pinheiro, M. T., Maciel, M. C., Silva, L. A., Lopes, A. S., Barroqueiro, E. S., Borges, M. O., Guerra, R. N., and Nascimento, F. R. Anti-thrombotic effect of
Babassu Overview
Babassu palm (Attalea speciosa) is a tall tree native to South America, mainly found in the Amazon Rainforest of Brazil. Its fruit contains seeds rich in babassu oil, with the dried, powdered mesocarp (inner husk layer) and extracted kernel oil being the primary parts used. The mesocarp provides starch, protein, lipid, soluble carbohydrates, fiber, and minerals, along with glucan MP1, tannins, steroid compounds, and triterpenes. Babassu oil is particularly rich in medium-chain triglycerides.
Research indicates that babassu oil possesses anti-inflammatory properties. Studies show it stimulates fibroblast migration, inhibits nitric oxide production in lipopolysaccharide-stimulated peritoneal macrophages, and boosts interferon-gamma and interleukin 6 levels. Topical application of babassu oil in mice models reduced swelling, hyperplasia, and myeloperoxidase activity, indicating its potential in managing inflammation. Additionally, a constituent in babassu mesocarp, glucan MP1, has been found to enhance phagocytosis and reduce acetic acid-induced vascular permeability, early-stage inflammatory reactions. However, some studies suggest that an aqueous extract of babassu mesocarp flour may activate peritoneal macrophages, leading to increased nitric oxide and hydrogen peroxide production, tumor necrosis factor (TNF) release, and MHC class II expression.
dabigatran Overview
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Dabigatran is used to treat deep vein thrombosis (DVT; a blood clot, usually in the leg) and pulmonary embolism (PE; a blood clot in the lung) in adults and children 3 months of age and older who have been treated with an injectable anticoagulant ('blood thinner'). It is also used to reduce the risk of a DVT and PE from happening again after initial treatment is completed in adults and children 3 months of age and older. Dabigatran is used to help prevent DVT and PE in adults who have had hip replacement surgery. Dabigatran is also used to help prevent strokes or serious blood clots in adults who have atrial fibrillation (a condition in which the heart beats irregularly, increasing the chance of clots forming in the body, and possibly causing strokes) without heart valve disease. Dabigatran is in a class of anticoagulant medications called direct thrombin inhibitors. It works by preventing blood clots from forming in the body.
Babassu - More Interactions
Babassu interacts with 126 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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