Drug & supplement interaction

Black Alder + Naltrexone Hydrochloride

Naltrexone Hydrochloride brand name: Revia.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Black Alder and Naltrexone Hydrochloride in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Black Alder and Naltrexone Hydrochloride

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Naltrexone Hydrochloride and Black Alder in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Black Alder safety at a glance

Black Alder overall Use caution Limited safety data exist and it may cause nausea or stomach upset, so use cautiously and briefly.
Pregnancy Avoid There is not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid Safety while breastfeeding is unknown, so avoiding it is the safer choice.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Naltrexone Hydrochloride and Black Alder? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Naltrexone Hydrochloride

Interactions in our licensed database are recorded against drug classes, not just single drug names. Naltrexone Hydrochloride is filed under 3 classifications — including hepatotoxic drugs, oral drugs. Black Alder has documented interactions with 2 drug classes — the most serious being cisplatin (platinol-aq) (moderate) and doxorubicin (adriamycin, others) (moderate) — and none of Naltrexone Hydrochloride’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Black Alder Does Interact With Other Medications

Black Alder has 2 moderate known drug interactions in our database — Naltrexone Hydrochloride isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Black Alder

Covers the 2,830 medications we’ve checked against Black Alder. Pick one to open its full report.

What to actually watch for

What Naltrexone Hydrochloride’s Own FDA Label Lists

This is not an interaction — none of it involves Black Alder. These are the most notable effects listed in the ADVERSE REACTIONS section of Naltrexone Hydrochloride’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Dependence or withdrawal symptoms Worth acting on
  • A stroke or mini-stroke Worth acting on
  • A bowel blockage Worth acting on
  • Dehydration Worth acting on
  • A heart attack Worth acting on
  • Blood clots Worth acting on
  • Pancreatitis Worth acting on
  • Heart failure Worth acting on
  • Fainting Worth acting on
  • An irregular heartbeat Worth acting on

Showing the 10 most notable of 62 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Naltrexone Hydrochloride. Read the label on DailyMed › Where a percentage is shown, it is the share of 9,867 voluntary FDA FAERS reports for Naltrexone Hydrochloride that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Black Alder’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Black Alder side to compare — that is a limit of the record, not a statement that Black Alder has no side effects.

Everything else you take

See Every Supplement That Interacts With Naltrexone Hydrochloride

This page covers Black Alder only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Naltrexone Hydrochloride page lists 56 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Siberian Cocklebur (major), Wine (major) and Ashwagandha (moderate).

Open the Naltrexone Hydrochloride interaction page

One more smart check

Taking Black Alder as Part of a Dietary Supplement Product? Check It for Interactions

We hold 21 real supplement products containing Black Alder, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Black Alder. Even though Black Alder itself has no known interaction with Naltrexone Hydrochloride, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Black Alder and Naltrexone Hydrochloride Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Black Alder
Steady interest

#1,168 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Naltrexone Hydrochloride
Steady interest

#1,529 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Black Alder reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Black Alder and Naltrexone Hydrochloride records this page draws on were last updated July 3, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Black Alder

What is Black Alder?

Black Alder
  • Sore throat and mouth inflammation
  • Skin wounds and irritation (topical)
  • Fever and general aches (traditional)
  • Digestive complaints
  • Astringent for minor bleeding

Black Alder is a European tree whose bark and leaves have a long history in folk medicine, mainly as an astringent gargle or wound wash. There is very little modern human research to confirm any of these uses, and it can cause stomach upset, so it should be used cautiously and avoided during pregnancy and breastfeeding.

Alnus glutinosa · Betulaceae · Bark, leaves, and sometimes the catkins · Dried bark or leaf for tea, decoctions, tinctures, and gargles or mouth rinses

An interaction check asks whether these two react with each other — it does not ask whether Black Alder is a good idea for someone in your situation. Here is what our Black Alder record says about it on its own.

Black Alder: dosing

There is no established, standardized dose for Black Alder. Traditional use involved making a tea or decoction from the dried bark or leaves, or using a diluted preparation as a gargle or skin wash.If you choose to use a product, follow the directions on the label and do not exceed the recommended amount.

From our Black Alder monograph — the full record covers uses, side effects and every documented interaction.

Read the full Black Alder monograph & all interactions
Medication

About Naltrexone

What Is Naltrexone Used For?

Brand name: Revia

Naltrexone Hydrochloride tablets are used to treat alcohol dependence and to block the effects of opioids in people being treated for opioid dependence. It works best as part of a full treatment program that includes counseling and support.

The extended-release injectable suspension (brand name Vivitrol) is used to treat alcohol dependence in patients who are already not drinking before starting treatment, and to prevent relapse to opioid dependence after a patient has completed opioid detoxification. Vivitrol must always be part of a comprehensive treatment program that includes psychosocial support.

See full Naltrexone drug information
Keep checking

Other Drugs & Black Alder

Browse every other medication we’ve checked against Black Alder — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
2Moderate
0Minor
2,827No known interaction
Moderate

2 interactions

No interaction 2,827 drugs checked — show the list
Evidence & sources

Black Alder References

The 1 references that drive our Black Alder monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Dinic J, Novakovic M, Podolski-Renic A, et al. Antioxidative activity of diarylheptanoids from the bark of black alder (Alnus glutinosa) and their interaction with anticancer drugs. Planta Med 2014;80(13):1088-96. doi: 10.1055/s-0034-1382993. Epub 2014 Au PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Black Alder and Naltrexone Hydrochloride Together: Common Questions

Is it safe to take Black Alder with Naltrexone Hydrochloride?
We do not list a known interaction between Black Alder and Naltrexone Hydrochloride. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Black Alder and Naltrexone Hydrochloride combination checked?
Interactions in our licensed database are recorded against drug classes. Naltrexone Hydrochloride is filed under 3 classifications, and Black Alder has documented interactions with 2 drug classes — none of Naltrexone Hydrochloride's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Black Alder interact with any other medications?
Yes. Black Alder has 2 documented drug interactions in our database — Naltrexone Hydrochloride is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Naltrexone Hydrochloride interact with any supplements?
Yes. Naltrexone Hydrochloride has documented interactions with 56 supplements in our database — Black Alder is not one of them. The Naltrexone Hydrochloride interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Naltrexone Hydrochloride and Black Alder?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.