Drug & supplement interaction

Cocillana + Tinidazole

Tinidazole brand name: Tindamax.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Cocillana and Tinidazole in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Tinidazole states a food rule worth keeping to.

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Interaction report

Cocillana and Tinidazole

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Tinidazole and Cocillana in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Cocillana at all — not against Tinidazole, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Cocillana safety at a glance

Cocillana overall Use caution It is used in some cough products but lacks strong safety and effectiveness data, and large doses can cause vomiting.
Pregnancy Possibly Unsafe When used orally due to its purported ability to induce menstruation. Read the full pregnancy detail
Breastfeeding Avoid Safety while breastfeeding is unknown, so avoid it unless your doctor advises otherwise.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Tinidazole and Cocillana? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Tinidazole’s Own FDA Label Lists

This is not an interaction — none of it involves Cocillana. These are the most notable effects listed in the ADVERSE REACTIONS section of Tinidazole’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Pain or burning when passing urine Worth acting on
  • Unsteadiness Worth acting on
  • Wheezing Worth acting on
  • Confusion Worth acting on
  • A severe skin reaction Worth acting on
  • Seizures Worth acting on
  • Low mood Worth acting on
  • A low platelet count Worth acting on
  • Shortness of breath Worth acting on
  • A severe allergic reaction Worth acting on

Showing the 10 most notable of 40 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Tinidazole. Read the label on DailyMed › Cocillana’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Cocillana side to compare — that is a limit of the record, not a statement that Cocillana has no side effects.

Special populations

Cocillana in Pregnancy & Breastfeeding

Pregnancy Possibly Unsafe

When used orally due to its purported ability to induce menstruation.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

How to take them

Some Tinidazole Products Have a Food Rule — Cocillana Should Not Break It

At least one FDA label for a product containing Tinidazole says to take it with food. If you take Cocillana on an empty stomach out of habit, keep them separate — and take Tinidazole with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Tinidazole products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

2 DOSAGE AND ADMINISTRATION 2 DOSAGE AND ADMINISTRATION Trichomoniasis: a single 2 g oral dose taken with food.

From the Dosage and Administration section of the FDA label we read for Tinidazole — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Tinidazole

This page covers Cocillana only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tinidazole page lists 140 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 96 moderate · 41 minor.

From our pharmacist’s overview on the Tinidazole page

“Tinidazole (Tindamax) is a short antibiotic course, often for parasitic or vaginal infections, and its supplement list is one I would genuinely slow down for. Each of the three major-rated pairings can wreck treatment in its own way: St.”

Reviewed by 2 · Jul 18, 2026

Open the Tinidazole interaction page

How much people look this up

Where Cocillana and Tinidazole Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Cocillana
Steady interest

#1,194 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Tinidazole
Steady interest

#1,600 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Cocillana reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Cocillana and Tinidazole records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Cocillana

What is Cocillana?

  • Cough relief
  • Chest congestion
  • Loosening mucus (expectorant)
  • Bronchitis symptoms

Cocillana is a tree bark traditionally used as an expectorant in cough and cold remedies, often blended with other ingredients. There is very little modern scientific evidence to confirm how well it works, and it can cause nausea or vomiting in higher amounts, so use it cautiously and check with a pharmacist first.

Guarea rusbyi · Meliaceae · Dried bark · Liquid extract, tincture, syrup (often combined with other cough ingredients), tablets

An interaction check asks whether these two react with each other — it does not ask whether Cocillana is a good idea for someone in your situation. Here is what our Cocillana record says about it on its own.

Cocillana: dosing

There is no well-established standardized dose for cocillana, and it is usually found as one ingredient among several in cough products. Because higher doses can cause vomiting, the amounts used are typically small.If you choose to use a product containing cocillana, follow the directions on the label exactly and do not take more than recommended.

From our Cocillana monograph — the full record covers uses, side effects and every documented interaction.

Read the full Cocillana monograph & all interactions
Medication

About Tinidazole

What Is Tinidazole Used For?

Brand name: Tindamax

Tinidazole tablets treat four types of infections: trichomoniasis (a sexually transmitted infection), giardiasis (a parasitic gut infection), amebiasis (including intestinal infection and amebic liver abscess), and bacterial vaginosis (a vaginal bacterial imbalance). Treatment of giardiasis and amebiasis is approved for adults and children older than three years of age. Bacterial vaginosis is an approved use in adult women.

Because trichomoniasis is sexually transmitted, sexual partners must be treated at the same time to prevent re-infection. Tinidazole should only be used for confirmed or strongly suspected bacterial or parasitic infections — using it unnecessarily can contribute to antibiotic resistance.

See full Tinidazole drug information
Keep checking

Other Drugs & Cocillana

Browse every other medication we’ve checked against Cocillana — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Cocillana against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Cocillana list.

See the full Cocillana interactions page
See every supplement checked against Tinidazole, ranked by severity
Evidence & sources

Cocillana References

The 1 references that drive our Cocillana monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Cocillana and Tinidazole Together: Common Questions

Is it safe to take Cocillana with Tinidazole?
We do not list a known interaction between Cocillana and Tinidazole. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Cocillana and Tinidazole at the same time of day?
At least one FDA label for a product containing Tinidazole says to take it with food. If you take Cocillana on an empty stomach out of habit, keep them separate and take Tinidazole with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Tinidazole products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Tinidazole interact with any supplements?
Yes. Tinidazole has documented interactions with 140 supplements in our database — Cocillana is not one of them. The Tinidazole interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Cocillana monograph Uses, safety profile, and every drug interaction in one place Tinidazole drug information The full plain-English guide to this medication Tinidazole supplement interactions Every supplement checked against Tinidazole, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Tinidazole and Cocillana?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.