Cyclamen + Vericiguat
Vericiguat brand name: Verquvo.
We found no known interaction between Cyclamen and Vericiguat in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Vericiguat states a food rule worth keeping to.
Cyclamen and Vericiguat
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Vericiguat and Cyclamen in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Cyclamen at all — not against Vericiguat, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Cyclamen safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Cyclamen in Pregnancy & Breastfeeding
When used orally; avoid using.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
Some Vericiguat Products Have a Food Rule — Cyclamen Should Not Break It
At least one FDA label for a product containing Vericiguat says to take it with food. If you take Cyclamen on an empty stomach out of habit, keep them separate — and take Vericiguat with a meal where the label says to.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Vericiguat products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
2 DOSAGE AND ADMINISTRATION The recommended starting dose of VERQUVO is 5 mg orally once daily with food.
From the Dosage and Administration section of the FDA label we read for Vericiguat — where that label names a specific product, the instruction is that product's. See the Vericiguat drug page ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
See Every Supplement That Interacts With Vericiguat
This page covers Cyclamen only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Vericiguat page lists 54 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), St. John's Wort (major), Bitter Melon (moderate), Black Pepper (moderate) and Bulbine Natalensis (moderate).
By severity: 2 major · 35 moderate · 17 minor.
From our pharmacist’s overview on the Vericiguat page
“No supplement on this page worries me more for vericiguat (Verquvo) users than St. John's wort.”
Reviewed by 2 · Jul 18, 2026
Where Cyclamen and Vericiguat Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#944 of 1,452 supplements looked up here in the last 7 days
#2,275 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Cyclamen reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Cyclamen and Vericiguat records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Cyclamen
What is Cyclamen?
- Sinus congestion (sinusitis)
- Headache and migraine (traditional/homeopathic)
- Menstrual complaints (traditional use)
- Digestive complaints (traditional use)
Cyclamen is an ornamental plant whose tuber contains potentially toxic compounds called saponins. It has been studied mostly as a nasal preparation for sinus congestion, but evidence is limited and the raw plant can be poisonous, so it should not be used without professional guidance.
Cyclamen europaeum · Primulaceae · Tuber (root); sometimes leaves and flowers · Homeopathic preparations, nasal sprays/extracts (in some regions), and rarely tinctures
An interaction check asks whether these two react with each other — it does not ask whether Cyclamen is a good idea for someone in your situation. Here is what our Cyclamen record says about it on its own.
Cyclamen: dosing
There is no well-established, standardized dose of cyclamen for general use. Because the plant is toxic, dosing should never be guessed or self-made.If you use a commercial product, such as a nasal preparation or homeopathic remedy, follow the directions on the label exactly and do not exceed the recommended amount.
From our Cyclamen monograph — the full record covers uses, side effects and every documented interaction.
About Vericiguat
What Is Vericiguat Used For?
Brand name: Verquvo
Verquvo (vericiguat) is used to reduce the risk of cardiovascular death and hospitalization due to heart failure. It is specifically for adults with symptomatic chronic heart failure whose heart pumps with reduced function (ejection fraction less than 45%), following a recent hospitalization for heart failure or a need for IV diuretics given outside the hospital.
Verquvo is taken on top of other standard heart failure treatments — it is not a replacement for them.
Most-Reported Side Effects for Vericiguat
From FAERS, the FDA’s public side-effect reporting system (966 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Cyclamen
Browse every other medication we’ve checked against Cyclamen — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Cyclamen against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Losartan Potassium ›
- Testosterone ›
- Ivermectin ›
- Abemaciclib ›
- Aspirin ›
- Metoprolol ›
- Acetaminophen ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Tadalafil ›
- Docusate ›
- Tirzepatide ›
- Ibuprofen ›
- Methamphetamine ›
- Hydroxyurea ›
- Warfarin Sodium ›
- Valacyclovir ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Lisdexamfetamine ›
- Propranolol ›
- Metformin ›
- Amitriptyline ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Methotrexate ›
- Amlodipine Besylate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Fluoxetine ›
- Doxycycline ›
- Acyclovir ›
- Azithromycin ›
- Lamotrigine ›
- Pregabalin ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Quetiapine ›
- Clonazepam ›
- Levothyroxine, Liothyronine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Methylene Blue ›
- Duloxetine ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Cyclamen list.
Cyclamen References
The 4 references that drive our Cyclamen monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Jaspersen-Schib R, Theus L, Guirguis-Oeschger M, et al. [Serious plant poisonings in Switzerland 1966-1994. Case analysis from the Swiss Toxicology Information Center]. Schweiz Med Wochenschr 1996;126:1085-98.
- Pfaar O, Mullol J, Anders C, Hörmann K, Klimek L. Cyclamen europaeum nasal spray, a novel phytotherapeutic product for the management of acute rhinosinusitis: a randomized double-blind, placebo-controlled trial. Rhinology 2012;50(1):37-44. doi: 10.4193/Rh DOI
- Ponikau JU, Hamilos DL, Barreto A, et al. An exploratory trial of Cyclamen europaeum extract for acute rhinosinusitis. Laryngoscope 2012;122(9):1887-92. doi: 10.1002/lary.23366.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Cyclamen and Vericiguat Together: Common Questions
Is it safe to take Cyclamen with Vericiguat?
Should I take Cyclamen and Vericiguat at the same time of day?
Does Vericiguat interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.