Docosahexaenoic Acid (dha) - Rinvoq (Upadacitinib Hemihydrate) Interaction
Herbal: Docosahexaenoic Acid (dha)
Also Known As: ADH, DHA, Fish Oil Fatty Acid, N-3 Fatty Acid, Neuromins, Omega 3, Omega 3 Fatty Acids, Omega-3, Omega-3 Fatty Acids, W-3 Fatty Acid
Drug: Upadacitinib Hemihydrate
Brand names:
Rinvoq
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jun 08, 2025
Interaction Details
There were no interactions found between Upadacitinib Hemihydrate and Docosahexaenoic Acid (dha). This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Docosahexaenoic Acid (dha) Overview
DHA (docosahexaenoic acid) is an omega-3 fatty acid that is important for the proper functioning of the nervous system and eyes.
DHA can be found in a variety of foods and in abundance in many different types of fatty fish, such as salmon and mackerel. It is a popular dietary supplement, consistently among the most utilized.
There is some evidence to suggest that DHA may have a number of potential health benefits, including improving cognitive function and reducing the risk of age-related cognitive decline. It has also been shown to be important for fetal and infant brain development and is a common component in prenatal vitamins.
DHA is often combined with EPA (eicosapentaenoic acid) in dietary supplements and both are found together in most fish-sourced ones. One main difference between DHA and EPA is their structure. DHA is a long-chain fatty acid, while EPA is a medium-chain fatty acid. This difference in structure may affect how they are utilized in the body and their potential health benefits. For example, DHA is more highly concentrated in the brain and is believed to be important for brain and eye health, while EPA is more highly concentrated in the heart and may be helpful in reducing inflammation and improving cardiovascular health.
Upadacitinib Hemihydrate Overview
-
Upadacitinib is used alone or with other medications to treat rheumatoid arthritis (condition in which the body attacks its own joints causing pain, swelling, and loss of function) in people who are unable to take or have not responded well to one or more tumor necrosis factor (TNF) inhibitor medication(s). It is also used to treat psoriatic arthritis (a condition that causes joint pain and swelling and scales on the skin) in adults who are unable to take or did not respond to or tolerate one or more TNF inhibitor medication(s). Upadacitinib is also used to treat symptoms of eczema (atopic dermatitis; a skin disease that causes the skin to be dry and itchy and to sometimes develop red, scaly rashes) in adults and children 12 years and older who cannot use other medications for their condition or whose eczema has not responded to other medications. It is also used to treat ulcerative colitis (a condition that causes swelling and sores in the lining of the colon [large intestine] and rectum) in adults who are unable to take or who did not respond to one or more TNF inhibitor medication(s). Upadacitinib is used to treat ankylosing spondylitis (a condition in which the body attacks the joints of the spine and other areas, causing pain, swelling, and joint damage) in adults who are unable to take or who did not respond to one or more TNF inhibitor medication(s). Upadacitinib is in a class of medications called Janus kinase (JAK) inhibitors. It works by decreasing the activity of the immune system.
Docosahexaenoic Acid (dha) - More Interactions
Docosahexaenoic Acid (dha) interacts with 370 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
Return to the main supplement interaction checker page
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
Ask A Pharmacist About Your Herbal Questions!
Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
Ask A Pharmacist