Drug & supplement interaction

Elm Bark + Deucravacitinib

Deucravacitinib brand name: Sotyktu.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Elm Bark and Deucravacitinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Elm Bark and Deucravacitinib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Deucravacitinib and Elm Bark in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Elm Bark at all — not against Deucravacitinib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Elm Bark safety at a glance

Elm Bark overall Use caution Likely low-risk for short-term use in healthy adults, but human safety data are limited.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid No reliable safety data while breastfeeding, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Deucravacitinib and Elm Bark? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Deucravacitinib’s Own FDA Label Lists

This is not an interaction — none of it involves Elm Bark. These are the most notable effects listed in the ADVERSE REACTIONS section of Deucravacitinib’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 4 of them are worth acting on rather than waiting out — marked below.

  • Severe muscle breakdown Worth acting on
  • Kidney problems Worth acting on
  • Liver problems Worth acting on
  • A higher chance of infection Worth acting on
  • Acne mentioned in 8.7% of FDA reports for Deucravacitinib
  • Mouth irritation or sores
  • A stuffy or runny nose
  • Sore throat
  • Joint pain
  • A skin rash mentioned in 7.0% of FDA reports for Deucravacitinib

From the ADVERSE REACTIONS section of the FDA label for Deucravacitinib. Read the label on DailyMed › Where a percentage is shown, it is the share of 2,800 voluntary FDA FAERS reports for Deucravacitinib that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Elm Bark’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Elm Bark side to compare — that is a limit of the record, not a statement that Elm Bark has no side effects.

Everything else you take

See Every Supplement That Interacts With Deucravacitinib

This page covers Elm Bark only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Deucravacitinib page lists 106 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Siberian Cocklebur (major), Wine (major) and Active Hexose Correlated Compound (ahcc) (moderate).

By severity: 4 major · 92 moderate · 10 minor.

From our pharmacist’s overview on the Deucravacitinib page

“Deucravacitinib (Sotyktu) calms an overactive immune system to treat plaque psoriasis, which is exactly why its 106 supplement interactions deserve genuine respect. The biggest group, 53 ingredients, may stimulate immune function and could blunt the drug's benefit.”

Reviewed by 2 · Jul 18, 2026

Open the Deucravacitinib interaction page

How much people look this up

Where Elm Bark and Deucravacitinib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Elm Bark
Steady interest

#1,376 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Deucravacitinib
Steady interest

#2,575 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Elm Bark is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Elm Bark reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Elm Bark and Deucravacitinib records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Elm Bark

What is Elm Bark?

Elm Bark
  • Diarrhea
  • Gastritis and stomach upset
  • Mild inflammation
  • Skin irritation
  • Sore throat

Elm bark (from Ulmus minor) has a long history in traditional medicine for digestive complaints and minor inflammation, but high-quality human studies are lacking, so its true effectiveness is unknown. It is generally considered low-risk for short-term use in adults, but it should not be confused with slippery elm (Ulmus rubra). Talk to a pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have a health condition.

Ulmus minor · Ulmaceae · Bark · Dried bark, powder, tea, tincture/liquid extract, capsules

An interaction check asks whether these two react with each other — it does not ask whether Elm Bark is a good idea for someone in your situation. Here is what our Elm Bark record says about it on its own.

Elm Bark: dosing

There is no well-established standard dose for elm bark. Because human studies are lacking, no reliable, evidence-based amount has been set.If you use a commercial product, follow the directions on the label and do not exceed the recommended amount. Use it for short periods only, and stop if you have any unwanted effects.

From our Elm Bark monograph — the full record covers uses, side effects and every documented interaction.

Read the full Elm Bark monograph & all interactions
Medication

About Deucravacitinib

What Is Deucravacitinib Used For?

Brand name: Sotyktu

Sotyktu (deucravacitinib) is approved to treat two conditions in adults. First, it treats moderate-to-severe plaque psoriasis in people who are candidates for systemic (body-wide) therapy or phototherapy (light therapy). It is not recommended to combine Sotyktu with other strong immune-suppressing medications for this use.

Second, Sotyktu is approved to treat active psoriatic arthritis in adults.

Most-Reported Side Effects for Deucravacitinib

From FAERS, the FDA’s public side-effect reporting system (2,800 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Acne 243 reports
Pruritus 226 reports
Rash 195 reports
Psoriasis 174 reports
Erythema 153 reports
See full Deucravacitinib drug information
Keep checking

Other Drugs & Elm Bark

Browse every other medication we’ve checked against Elm Bark — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Elm Bark against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Elm Bark list.

See the full Elm Bark interactions page
See every supplement checked against Deucravacitinib, ranked by severity
Evidence & sources

Elm Bark References

The 2 sources that drive our Elm Bark monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Elm Bark is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Slippery Elm — MedlinePlus (NIH) Source
  2. Herbs at a Glance — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Elm Bark and Deucravacitinib Together: Common Questions

Is it safe to take Elm Bark with Deucravacitinib?
We do not list a known interaction between Elm Bark and Deucravacitinib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Deucravacitinib interact with any supplements?
Yes. Deucravacitinib has documented interactions with 106 supplements in our database — Elm Bark is not one of them. The Deucravacitinib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Elm Bark monograph Uses, safety profile, and every drug interaction in one place Deucravacitinib drug information The full plain-English guide to this medication Deucravacitinib supplement interactions Every supplement checked against Deucravacitinib, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Deucravacitinib and Elm Bark?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.