Drug & supplement interaction

Gelatin + Uridine Triacetate

Uridine Triacetate brand names: Xuriden, Vistogard.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Gelatin and Uridine Triacetate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Uridine Triacetate states a food rule worth keeping to.

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Interaction report

Gelatin and Uridine Triacetate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Uridine Triacetate and Gelatin in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Gelatin at all — not against Uridine Triacetate, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Gelatin safety at a glance

Gelatin overall Generally safe Gelatin is widely consumed as a food and is generally considered safe for most people.
Pregnancy Likely Safe When used orally in the amounts commonly found in foods. Read the full pregnancy detail
Breastfeeding Likely Safe When used orally in the amounts commonly found in foods. There is insufficient reliable information available about the safety of using larger amounts of gelati... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Uridine Triacetate and Gelatin? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Gelatin Itself Has Been Linked To

This is not an interaction — nothing below involves Uridine Triacetate. It is the side-effect record for Gelatin on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Gelatin, this list is the first place to look. 2 entries are worth acting on rather than waiting out — marked below.

  • A slow heartbeat / Wheezing / Kidney problems / A severe allergic reaction / Hives Worth acting on Additional detail

    “Gelatin can cause allergic reactions. Gelatin in foods can cause initial sensitization. Gelatin-containing medicines including oral medications, suppositories, vaccines, and injectable products can cause IgE-mediated allergic reactions, including urticaria, angioedema, wheezing, hypotension, and anaphylaxis.”

    Gelatin · Natural Medicines adverse-effect record, reported in hypotension.

    6 sources cited
    1. 7703. Schwick HG, Heide K. Immunochemistry and immunology of collagen and gelatin. Bibl Haematol 1969;33:111-25. PubMed
    2. 7708. Kelso JM. The gelatin story. J Allergy Clin Immunol 1999;103:200-2.
    3. 7709. Nakayama T, Aizawa C, Kuno-Sakai H. A clinical analysis of gelatin allergy and determination of its causal relationship to the previous administration of gelatin-containing acellular pertussis vaccine combined with diphtheria and tetanus toxoids. J Allerg PubMed
    4. 7710. Sakaguchi M, Inouye S. Anaphylaxis to gelatin-containing rectal suppositories. J Allergy Clin Immunol 2001;108:1033-4. PubMed
    5. 97633. Ventura Spagnolo E, Calapai G, Minciullo PL, Mannucci C, Asmundo A, Gangemi S. Lethal anaphylactic reaction to intravenous gelatin in the course of surgery. Am J Ther. 2016;23(6):e1344-e1346. PubMed
    6. 111345. Coury JR, Skaggs KF, Marciano GF, et al. Intraoperative Anaphylaxis to the Bovine Flowable Gelatin Matrix: A Report of 2 Cases. JBJS Case Connect 2022;12(1). PubMed
  • An allergic reaction Worth acting on Additional detail

    “Orally, gelatin seems to be well tolerated.

    Most Common Adverse Effects:

    Oral: Belching, bloating, and dyspepsia.

    Serious Adverse Effects (Rare):

    Injection: IgE-mediated allergic reactions, Kounis syndrome.”

    Gelatin · Natural Medicines adverse-effect record, reported in dyspepsia.

  • Bloating or gas / Stomach upset Additional detail

    “Orally, gelatin can cause unpleasant taste, sensation of heaviness in the stomach, bloating, dyspepsia, and belching.”

    Gelatin · Natural Medicines adverse-effect record, reported in dyspepsia.

    1 source cited
    1. 7704. Moskowitz RW. Role of collagen hydrolysate in bone and joint disease.Semin Arthritis Rheum 2000;30:87-99. PubMed
  • A fast or pounding heartbeat / Low blood pressure Additional detail

    Recorded for Gelatin in the same Natural Medicines adverse-effect record shown under A slow heartbeat / Wheezing / Kidney problems / A severe allergic reaction / Hives above.

Everything above comes from the Natural Medicines adverse-effect record for Gelatin — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Uridine Triacetate’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Uridine Triacetate column appears here.

Special populations

Gelatin in Pregnancy & Breastfeeding

Pregnancy Likely Safe

When used orally in the amounts commonly found in foods.

Pregnancy Possibly Safe

When a specific type of gelatin from donkey hide, called colla corii asini, is used orally in doses of 10 grams daily for 6 weeks. Higher doses of 15 grams daily have been associated with an increased risk of inflammatory adverse effects, including sore throat, swollen gums, local eczema, and ulcers in the oral cavity. There is insufficient reliable information available about the safety of other types of gelatin when used during pregnancy in medicinal amounts.

Lactation Likely Safe

When used orally in the amounts commonly found in foods. There is insufficient reliable information available about the safety of using larger amounts of gelatin during lactation; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

How to take them

Some Uridine Triacetate Products Have a Food Rule — Gelatin Should Not Break It

At least one FDA label for a product containing Uridine Triacetate says to take it with food. If you take Gelatin on an empty stomach out of habit, keep them separate — and take Uridine Triacetate with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Uridine Triacetate products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

Administer the dose with food (applesauce, pudding or yogurt) or in milk or infant formula.

From the Dosage and Administration section of the FDA label we read for Uridine Triacetate — where that label names a specific product, the instruction is that product's. See the Uridine Triacetate drug page ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Uridine Triacetate

This page covers Gelatin only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Uridine Triacetate page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Uridine Triacetate page

“Uridine triacetate is a drug you take when absorption truly cannot fail, whether as Vistogard, the emergency antidote for fluorouracil or capecitabine overdose, or as Xuriden for hereditary orotic aciduria. That is why the 17 supplement interactions on file deserve real care rather than a shrug.”

Reviewed by 2 · Jul 18, 2026

Open the Uridine Triacetate interaction page

One more smart check

Taking Gelatin as Part of a Dietary Supplement Product? Check It for Interactions

We hold 269 real supplement products containing Gelatin, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Gelatin. Even though Gelatin itself has no known interaction with Uridine Triacetate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Gelatin and Uridine Triacetate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Gelatin
Top half

#502 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Uridine Triacetate
Steady interest

#2,402 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Gelatin reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Gelatin and Uridine Triacetate records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Gelatin

What is Gelatin?

  • Joint and bone health
  • Skin, hair, and nail support
  • Source of dietary protein
  • Digestive comfort
  • Capsule shells for medicines and supplements

Gelatin is a protein made from animal collagen, used as a food, a capsule ingredient, and a supplement for joint, skin, and bone health. For most health uses, the evidence is limited or mixed, though it is generally safe as a food. If you have allergies, dietary restrictions, or a health condition, check with your pharmacist or doctor first.

Collagen derived from animal skin, bones, and connective tissue (usually pork or beef) · Powder, capsules, gummies, food products (Jell-O type desserts), and collagen/gelatin drinks

An interaction check asks whether these two react with each other — it does not ask whether Gelatin is a good idea for someone in your situation. Here is what our Gelatin record says about it on its own.

Gelatin: dosing

There is no official, standardized dose of gelatin for any health condition. The amount used in studies varies widely, and it is not clear what dose, if any, provides a health benefit.If you choose to use a gelatin supplement, follow the directions on the product label and do not exceed the recommended amount.

From our Gelatin monograph — the full record covers uses, side effects and every documented interaction.

Read the full Gelatin monograph & all interactions
Medication

About Uridine Triacetate

What Is Uridine Triacetate Used For?

Brand names: Xuriden, Vistogard

Uridine triacetate is available as two different products for two distinct uses. Vistogard is used for emergency treatment after an overdose of the chemotherapy drugs fluorouracil or capecitabine — or when someone develops severe, early, or life-threatening side effects from those drugs (such as heart or nervous system problems, severe digestive reactions, or a dangerous drop in white blood cells) within 96 hours of their last dose.

Xuriden is used to treat hereditary orotic aciduria, a rare inherited condition in which the body cannot make enough of a building block called uridine, causing a buildup of orotic acid and problems with blood cell production and other body functions. Both products are approved for adults and children.

See full Uridine Triacetate drug information
Keep checking

Other Drugs & Gelatin

Browse every other medication we’ve checked against Gelatin — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Gelatin References

The 11 references that drive our Gelatin monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Schwick HG, Heide K. Immunochemistry and immunology of collagen and gelatin. Bibl Haematol 1969;33:111-25. PubMed
  3. Moskowitz RW. Role of collagen hydrolysate in bone and joint disease.Semin Arthritis Rheum 2000;30:87-99. PubMed
  4. Kelso JM. The gelatin story. J Allergy Clin Immunol 1999;103:200-2.
  5. Nakayama T, Aizawa C, Kuno-Sakai H. A clinical analysis of gelatin allergy and determination of its causal relationship to the previous administration of gelatin-containing acellular pertussis vaccine combined with diphtheria and tetanus toxoids. J Allerg PubMed
  6. Sakaguchi M, Inouye S. Anaphylaxis to gelatin-containing rectal suppositories. J Allergy Clin Immunol 2001;108:1033-4. PubMed
  7. PDR Electronic Library. Montvale, NJ: Medical Economics Company, Inc., 2001.
  8. de la Fuente Tornero E, Vega Castro A, de Sierra Hernández PÁ, et al. Kounis syndrome during anesthesia: Presentation of indolent systemic mastocytosis: A case report. A Case Rep. 2017;8(9):226-228. PubMed
  9. Ventura Spagnolo E, Calapai G, Minciullo PL, Mannucci C, Asmundo A, Gangemi S. Lethal anaphylactic reaction to intravenous gelatin in the course of surgery. Am J Ther. 2016;23(6):e1344-e1346. PubMed
  10. Li Y, He H, Yang L, Li X, Li D, Luo S. Therapeutic effect of Colla corii asini on improving anemia and hemoglobin compositions in pregnant women with thalassemia. Int J Hematol. 2016;104(5):559-565. PubMed
  11. Coury JR, Skaggs KF, Marciano GF, et al. Intraoperative Anaphylaxis to the Bovine Flowable Gelatin Matrix: A Report of 2 Cases. JBJS Case Connect 2022;12(1). PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Gelatin and Uridine Triacetate Together: Common Questions

Is it safe to take Gelatin with Uridine Triacetate?
We do not list a known interaction between Gelatin and Uridine Triacetate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Gelatin and Uridine Triacetate at the same time of day?
At least one FDA label for a product containing Uridine Triacetate says to take it with food. If you take Gelatin on an empty stomach out of habit, keep them separate and take Uridine Triacetate with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Uridine Triacetate products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Uridine Triacetate interact with any supplements?
Yes. Uridine Triacetate has documented interactions with 17 supplements in our database — Gelatin is not one of them. The Uridine Triacetate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Uridine Triacetate and Gelatin?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.