Herb Robert + Loperamide, Simethicone
Loperamide, Simethicone brand name: Imodium Advanced.
We found no known interaction between Herb Robert and Loperamide, Simethicone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Loperamide, Simethicone states a food rule worth keeping to.
Herb Robert and Loperamide, Simethicone
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Loperamide, Simethicone and Herb Robert in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Herb Robert at all — not against Loperamide, Simethicone, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Herb Robert safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Some Loperamide, Simethicone Products Have a Food Rule — Herb Robert Should Not Break It
At least one FDA label for a product containing Loperamide, Simethicone says to take it on an empty stomach. Most supplements — Herb Robert included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Loperamide, Simethicone on its own and move Herb Robert to a meal later in the day.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Loperamide, Simethicone products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
Directions drink plenty of clear fluids to help prevent dehydration caused by diarrhea take only on an empty stomach (1 hour before or 2 hours after a meal) take with a full (8 oz.) glass of water find right dose on chart below.
From the Dosage and Administration section of the FDA label we read for Loperamide, Simethicone — where that label names a specific product, the instruction is that product's.
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
See Every Supplement That Interacts With Loperamide, Simethicone
This page covers Herb Robert only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Loperamide, Simethicone page lists 82 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Henbane (major), Scopolia (major), St. John's Wort (major) and Angel's Trumpet (moderate).
By severity: 4 major · 59 moderate · 19 minor.
From our pharmacist’s overview on the Loperamide, Simethicone page
“Imodium Advanced combines loperamide, an anti-diarrheal opioid that normally stays out of the brain thanks to a transporter called P-glycoprotein, with simethicone for gas, and I treat its interaction list with more respect than most over-the-counter medicines warrant. Thirty-seven of the 82 interacting ingredients on file affect that…”
Reviewed by 2 · Jul 18, 2026
Where Herb Robert and Loperamide, Simethicone Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#822 of 1,452 supplements looked up here in the last 7 days
#2,548 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Herb Robert reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Herb Robert and Loperamide, Simethicone records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Herb Robert
What is Herb Robert?
- Digestive upset
- Wound and skin care
- Sore throat and mouth irritation
- Respiratory complaints
- General 'detox' tonic
Herb Robert is a traditional European herb used for digestion, wounds, and minor inflammation, but there is very little human research to confirm it works for any condition. It is likely fine in small amounts as a tea for most healthy adults, but its safety has not been well studied. Talk to your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.
Geranium robertianum · Geraniaceae · Above-ground parts (leaves, stems, and flowers) · Tea, tincture, dried herb, capsules, fresh poultice
An interaction check asks whether these two react with each other — it does not ask whether Herb Robert is a good idea for someone in your situation. Here is what our Herb Robert record says about it on its own.
Herb Robert: dosing
There is no established, standardized dose for Herb Robert. Traditional use involved brewing a small amount of the dried herb as a tea or applying crushed fresh leaves to the skin, but these amounts were not measured in a consistent, science-based way.If you choose to use a commercial product, follow the directions on the label and do not exceed the recommended amount.
From our Herb Robert monograph — the full record covers uses, side effects and every documented interaction.
Other Drugs & Herb Robert
Browse every other medication we’ve checked against Herb Robert — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Herb Robert against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Ivermectin ›
- Abemaciclib ›
- Testosterone ›
- Losartan Potassium ›
- Sertraline ›
- Rosuvastatin ›
- Acetaminophen ›
- Aspirin ›
- Metoprolol ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Rivaroxaban ›
- Isotretinoin ›
- Tirzepatide ›
- Levothyroxine, Liothyronine ›
- Ibuprofen ›
- Warfarin Sodium ›
- Amlodipine Besylate ›
- Docusate ›
- Metformin ›
- Prednisone ›
- Amitriptyline ›
- Methamphetamine ›
- Tadalafil ›
- Lisdexamfetamine ›
- Semaglutide ›
- Amphetamine ›
- Hydroxyurea ›
- Valacyclovir ›
- Sumatriptan ›
- Propranolol ›
- Amoxicillin ›
- Lisinopril ›
- Methotrexate ›
- Bupropion ›
- Azithromycin ›
- Fluoxetine ›
- Doxycycline ›
- Acetaminophen, Aspirin, Caffeine ›
- Pregabalin ›
- Gabapentin ›
- Dextroamphetamine ›
- Naproxen ›
- Lamotrigine ›
- Quetiapine ›
- Bendamustine ›
- Clonazepam ›
- Acyclovir ›
- Buspirone ›
- Duloxetine ›
- Omeprazole ›
- Citalopram ›
- Letrozole ›
- Methylene Blue ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Herb Robert list.
Herb Robert References
The 3 references that drive our Herb Robert monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Svendsen MT, Andersen KE, Thormann H, Paulsen E. Contact sensitization to Geranium robertianum L. in an amateur gardener. Contact Dermatitis. 2015;72(6):420-1.
- Panahi Y, Akhavan A, Sahebkar A, et al. Investigation of the effectiveness of Syzygium aromaticum, Lavandula angustifolia and Geranium robertianum essential oils in the treatment of acute external otitis: a comparative trial with ciprofloxacin. J Microbi PubMed
- Badaoui A, Pecquet C, Fargeas C, Mahé E. Contact dermatitis caused by Geranium robertianum with erythema multiforme-like reaction. Contact Dermatitis. 2017;77(6):423-424.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Herb Robert and Loperamide, Simethicone Together: Common Questions
Is it safe to take Herb Robert with Loperamide, Simethicone?
Should I take Herb Robert and Loperamide, Simethicone at the same time of day?
Does Loperamide, Simethicone interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.