Isopropylnorsynephrine - Aspirin, Caffeine, Codeine Phosphate Interaction

Interaction Details

Aspirin, Caffeine, Codeine Phosphate is classified as belonging to the following category: Stimulant Drugs

Theoretically, taking isopropylnorsynephrine with stimulant drugs might have additive effects and increase the risk of adverse cardiovascular effects.
Isopropylnorsynephrine is an investigational beta-agonist and a derivative of synephrine and octopamine, which are stimulant constituents of bitter orange. In vitro research shows that isopropylnorsynephrine is a highly selective, direct-acting beta-adrenergic receptor agonist with positive chronotropic effects. Theoretically, isopropylnorsynephrine may also have stimulant effects.

Interaction Rating

Likelihood of Occurrence

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists

References

• Cohen PA, Travis JC, Vanhee C, Ohana D, Venhuis BJ. Nine prohibited stimulants found in sports and weight loss supplements: deterenol, phenpromethamine (Vonedrine), oxilofrine, octodrine, beta-methylphenylethylamine (BMPEA), 1,3-dimethylamylamine (1,3-DMA
• Anderson WG. The sympathomimetic activity of N-isopropyloctopamine in vitro. J Pharmacol Exp Ther 1983;225(3):553-8.

Isopropylnorsynephrine - More Interactions

Isopropylnorsynephrine interacts with 340 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.