Miracle Fruit - Codeine Phosphate Interaction
Herbal: Miracle Fruit
Also Known As: Synsepalum dulcificum, Bumelia dulcifica, Richadellla dulcifica, Sideroxylon dulcificum, Agbayun, Fruit Miracle, Magic Berry, Miracle Berry, Miraculin, Miraculous Berry, Sweet Berry
Drug: Codeine Phosphate
Brand names:
Codeine
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 04, 2025
Interaction Details
There were no interactions found between Codeine Phosphate and Miracle Fruit. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Miracle Fruit Overview
Miracle fruit, also known as synsepalum dulcificum, is a small red berry native to West Africa. The active ingredient in the berry, called miraculin, temporarily alters the taste buds on the tongue, making sour and acidic foods taste sweet. Due to the effects of miraculin, it is sometimes used as a sugar substitute for people with diabetes or for those looking to reduce their sugar intake. The effects of miraculin can last for up to an hour after consumption. In addition to its use as a natural medicine, miracle berry is also commonly used as a novelty product (e.g., 'mberry miracle berry tablets'), promoted as a fun addition to parties and gatherings, where it is often used as part of a “flavor tripping” experience, where people consume sour and acidic foods, such as lemons or vinegar, and experience the change in taste sensation.
Codeine Phosphate Overview
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Codeine is used to relieve mild to moderate pain. It is also used, usually in combination with other medications, to reduce coughing. Codeine will help relieve symptoms but will not treat the cause of symptoms or speed recovery. Codeine belongs to a class of medications called opiate (narcotic) analgesics and to a class of medications called antitussives. When codeine is used to treat pain, it works by changing the way the brain and nervous system respond to pain. When codeine is used to reduce coughing, it works by decreasing the activity in the part of the brain that causes coughing.
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Codeine is also available in combination with acetaminophen (Capital and Codeine, Tylenol with Codeine), aspirin, carisoprodol, and promethazine and as an ingredient in many cough and cold medications. This monograph only includes information about the use of codeine. If you are taking a codeine combination product, be sure to read information about all the ingredients in the product you are taking and ask your doctor or pharmacist for more information.
Miracle Fruit - More Interactions
Miracle Fruit interacts with 84 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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