Mommy's Bliss Gripe Water - Kombiglyze (Saxagliptin, metformin XR) Interaction
Herbal: Mommy's Bliss Gripe Water
Drug: Saxagliptin, metformin XR
Brand names:
Kombiglyze
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Mar 22, 2023
Interaction Details
Saxagliptin, metformin XR is classified as belonging to the following category: Antidiabetes Drugs
Mommy's Bliss Gripe Water contains ginger. Theoretically, taking ginger with antidiabetes drugs might increase the risk of hypoglycemia (i.e., low blood sugar) as some studies suggest that ginger might increase insulin levels and/or decrease blood glucose levels. Based on the low amount of ginger contained in Mommy's Bliss Gripe Water, it is quite unlikely that it would cause significant changes to blood sugar, but it important to be aware of if your infant is diabetic.
Interaction Rating
Likelihood of Occurrence
UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Pharmacist Analysis
Studies are mixed regarding whether or not ginger has significant hypoglycemic effects and the concern with this interaction is combining multiple blood-sugar-lowering compounds.
However, in studies that have shown ginger lowering blood sugar, the risk of hypoglycemia (i.e., low blood sugar) was practically non-existent.
It's very unlikely that ginger would cause blood sugar to drop too low if combined with other blood sugar-lowering compounds, especially when you consider the very low amounts of ginger contained in Mommy's Bliss, but the interaction is nevertheless important to be aware of if your infant is diabetic.
References
- Anti-diabetic activity of Zingiber officinale in streptozotocin-induced type I diabetic rats. PubMed
- Analgesic, antiinflammatory and hypoglycaemic effects of ethanol extract of Zingiber officinale (Roscoe) rhizomes (Zingiberaceae) in mice and rats. PubMed
- Effects of ginger (Zingiber officinale) on plasma glucose level, HbA1c and insulin sensitivity in type 2 diabetic patients. PubMed
Mommy's Bliss Gripe Water Overview
Mommy's Bliss Gripe Water is an over-the-counter product used to soothe colicky babies and infants. It is important to note that 'Gripe water' has been used traditionally since at least the 1800s to help treat colic and gastrointestinal discomfort in infants but 'gripe water' is not a standardized formula. Generally, it is a liquid made from a combination of water and various herbs, such as ginger, fennel, chamomile, licorice, and cinnamon, among others. Some varieties may also contain alcohol or sugar. Mommy's Bliss Gripe water contains fennel seed and ginger. It does not contain sugar or alcohol.
Mommy's Bliss Gripe Water - More Interactions
Mommy's Bliss Gripe Water interacts with 788 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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