Drug & supplement interaction

Moneywort + Cyproheptadine

Cyproheptadine brand name: Periactin.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Moneywort and Cyproheptadine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Moneywort and Cyproheptadine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Cyproheptadine and Moneywort in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Moneywort at all — not against Cyproheptadine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Moneywort safety at a glance

Moneywort overall Not established There is little reliable human safety data, so use cautiously and consult a professional.
Pregnancy Avoid Safety has not been studied; avoid use during pregnancy.
Breastfeeding Avoid No reliable data on safety while breastfeeding; best to avoid.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Cyproheptadine and Moneywort? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Cyproheptadine’s Own FDA Label Lists

This is not an interaction — none of it involves Moneywort. These are the most notable effects listed in the ADVERSE REACTIONS section of Cyproheptadine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Trouble passing urine Worth acting on
  • Hallucinations Worth acting on
  • Yellowing of the skin or eyes Worth acting on
  • Wheezing Worth acting on
  • An irregular heartbeat Worth acting on
  • Confusion Worth acting on
  • Seizures Worth acting on
  • A low platelet count Worth acting on
  • Anemia Worth acting on
  • A severe allergic reaction Worth acting on

Showing the 10 most notable of 38 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Cyproheptadine. Read the label on DailyMed › Moneywort’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Moneywort side to compare — that is a limit of the record, not a statement that Moneywort has no side effects.

Everything else you take

See Every Supplement That Interacts With Cyproheptadine

This page covers Moneywort only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Cyproheptadine page lists 72 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Henbane (major), Scopolia (major), Alfalfa (moderate) and Angel's Trumpet (moderate).

By severity: 3 major · 57 moderate · 12 minor.

From our pharmacist’s overview on the Cyproheptadine page

“Cyproheptadine (Periactin) is an older antihistamine that dries you out and slows you down on its own, which is exactly why its supplement list warrants genuine care rather than a quick skim. Of the 72 ingredients on file, three carry a major rating.”

Reviewed by 2 · Jul 18, 2026

Open the Cyproheptadine interaction page

How much people look this up

Where Moneywort and Cyproheptadine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Moneywort
Steady interest

#794 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Cyproheptadine
Top half

#829 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Moneywort is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Moneywort reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Moneywort and Cyproheptadine records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Moneywort

What is Moneywort?

Moneywort
  • Wound healing
  • Mild diarrhea
  • Cough and respiratory complaints
  • Minor skin irritation
  • Mild bleeding (traditional)

Moneywort (Creeping Jenny) is a low-growing garden plant used in some folk traditions for wounds, coughs, and digestive upset, but there is very little scientific research to confirm any of these uses. Because solid safety and effectiveness data are lacking, it is best to talk with a pharmacist or doctor before using it, and to avoid it during pregnancy and breastfeeding.

Lysimachia nummularia · Primulaceae · Aerial parts (leaves, stems, and flowers) · Tea, dried herb, tincture, topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Moneywort is a good idea for someone in your situation. Here is what our Moneywort record says about it on its own.

Moneywort: dosing

There is no established or standardized dose for Moneywort. Because it has not been studied in well-designed human trials, experts cannot recommend a specific amount that is both safe and effective.If you choose to use a commercial product, follow the directions on the label and do not exceed them. A pharmacist can help you review the product and decide whether it is appropriate for you. When in doubt, less is safer, and always start with the smallest amount.

From our Moneywort monograph — the full record covers uses, side effects and every documented interaction.

Read the full Moneywort monograph & all interactions
Medication

About Cyproheptadine

What Is Cyproheptadine Used For?

Brand name: Periactin

Cyproheptadine treats a range of allergic conditions, including perennial and seasonal allergic rhinitis (year-round or seasonal nasal allergies), vasomotor rhinitis (non-allergic nasal symptoms), and allergic conjunctivitis (itchy, watery eyes caused by allergens or foods). It also helps with allergic skin reactions such as urticaria (hives) and angioedema (skin swelling).

Additional uses include cold urticaria (hives triggered by cold), dermatographism (skin that hives when scratched), and helping to calm allergic reactions to blood or plasma transfusions. It is also used as a supportive therapy alongside epinephrine after a severe allergic reaction (anaphylaxis) has been initially controlled.

See full Cyproheptadine drug information
Keep checking

Other Drugs & Moneywort

Browse every other medication we’ve checked against Moneywort — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Moneywort against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Moneywort list.

See the full Moneywort interactions page
See every supplement checked against Cyproheptadine, ranked by severity
Evidence & sources

Moneywort References

The 1 sources that drive our Moneywort monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Moneywort is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Using Dietary Supplements Wisely — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Moneywort and Cyproheptadine Together: Common Questions

Is it safe to take Moneywort with Cyproheptadine?
We do not list a known interaction between Moneywort and Cyproheptadine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Cyproheptadine interact with any supplements?
Yes. Cyproheptadine has documented interactions with 72 supplements in our database — Moneywort is not one of them. The Cyproheptadine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Moneywort monograph Uses, safety profile, and every drug interaction in one place Cyproheptadine drug information The full plain-English guide to this medication Cyproheptadine supplement interactions Every supplement checked against Cyproheptadine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Cyproheptadine and Moneywort?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.