Drug & supplement interaction

Moneywort + Phendimetrazine

Phendimetrazine brand names: Plegine, Metra, Weightrol.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Moneywort and Phendimetrazine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Moneywort and Phendimetrazine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Phendimetrazine and Moneywort in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Moneywort at all — not against Phendimetrazine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Moneywort safety at a glance

Moneywort overall Not established There is little reliable human safety data, so use cautiously and consult a professional.
Pregnancy Avoid Safety has not been studied; avoid use during pregnancy.
Breastfeeding Avoid No reliable data on safety while breastfeeding; best to avoid.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Phendimetrazine and Moneywort? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Phendimetrazine’s Own FDA Label Lists

This is not an interaction — none of it involves Moneywort. These are the most notable effects listed in the ADVERSE REACTIONS section of Phendimetrazine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 2 of them are worth acting on rather than waiting out — marked below.

  • Pain or burning when passing urine Worth acting on
  • Raised blood pressure Worth acting on
  • Tremor or shakiness
  • Flushing
  • Sweating
  • A fast or pounding heartbeat
  • Anxiety or restlessness
  • Trouble sleeping
  • Constipation
  • Stomach pain

Showing the 10 most notable of 14 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Phendimetrazine. Read the label on DailyMed › Moneywort’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Moneywort side to compare — that is a limit of the record, not a statement that Moneywort has no side effects.

Everything else you take

See Every Supplement That Interacts With Phendimetrazine

This page covers Moneywort only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Phendimetrazine page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Phendimetrazine page

“Of the 17 supplements on file for phendimetrazine, an appetite-suppressant stimulant prescribed short term for weight loss, activated charcoal is the one that demands real caution. Charcoal binds medications in the gut and can sharply cut how much of a drug your body absorbs, leaving you with less appetite control than your prescriptio…”

Reviewed by 2 · Jul 18, 2026

Open the Phendimetrazine interaction page

How much people look this up

Where Moneywort and Phendimetrazine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Moneywort
Steady interest

#1,259 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Phendimetrazine
Steady interest

#2,089 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Moneywort is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Moneywort reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Moneywort and Phendimetrazine records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Moneywort

What is Moneywort?

Moneywort
  • Wound healing
  • Mild diarrhea
  • Cough and respiratory complaints
  • Minor skin irritation
  • Mild bleeding (traditional)

Moneywort (Creeping Jenny) is a low-growing garden plant used in some folk traditions for wounds, coughs, and digestive upset, but there is very little scientific research to confirm any of these uses. Because solid safety and effectiveness data are lacking, it is best to talk with a pharmacist or doctor before using it, and to avoid it during pregnancy and breastfeeding.

Lysimachia nummularia · Primulaceae · Aerial parts (leaves, stems, and flowers) · Tea, dried herb, tincture, topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Moneywort is a good idea for someone in your situation. Here is what our Moneywort record says about it on its own.

Moneywort: dosing

There is no established or standardized dose for Moneywort. Because it has not been studied in well-designed human trials, experts cannot recommend a specific amount that is both safe and effective.If you choose to use a commercial product, follow the directions on the label and do not exceed them. A pharmacist can help you review the product and decide whether it is appropriate for you. When in doubt, less is safer, and always start with the smallest amount.

From our Moneywort monograph — the full record covers uses, side effects and every documented interaction.

Read the full Moneywort monograph & all interactions
Medication

About Phendimetrazine

What Is Phendimetrazine Used For?

Brand names: Plegine, Metra, Weightrol

Phendimetrazine is used short-term — typically a few weeks — to help manage obesity in adults who have a body mass index (BMI) of 30 or higher, or 27 or higher when other risk factors like high blood pressure, diabetes, or high cholesterol are present, and who have not lost enough weight through diet and exercise alone.

Phendimetrazine Tartrate extended-release capsules are specifically indicated for adults meeting those BMI criteria, including those with certain risk factors. Phendimetrazine Tartrate tablets are indicated for adults with a BMI of 30 or higher. Both forms are approved for use as a single medication only — not in combination with other weight-loss drugs or stimulants.

See full Phendimetrazine drug information
Keep checking

Other Drugs & Moneywort

Browse every other medication we’ve checked against Moneywort — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Moneywort References

The 1 sources that drive our Moneywort monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Moneywort is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Using Dietary Supplements Wisely — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Moneywort and Phendimetrazine Together: Common Questions

Is it safe to take Moneywort with Phendimetrazine?
We do not list a known interaction between Moneywort and Phendimetrazine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Phendimetrazine interact with any supplements?
Yes. Phendimetrazine has documented interactions with 17 supplements in our database — Moneywort is not one of them. The Phendimetrazine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Phendimetrazine and Moneywort?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.