Onion - Zegalogue (Dasiglucagon Hydrochloride) Interaction
Herbal: Onion
Also Known As: Allium cepa, Allii Cepae Bulbus, Cebolla, Échalote, Green Onion, Jeju Steamed Onion, Oignon, Oignon Vert, Onions, Palandu, Piyaj, Shallot
Drug: Dasiglucagon Hydrochloride
Brand names:
Zegalogue
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 25, 2025
Interaction Details
Dasiglucagon Hydrochloride is classified as belonging to the following category: Antidiabetes Drugs
Concomitant use of antidiabetes drugs with onion may increase the risk of hypoglycemia.
Animal research and clinical research shows that taking onion can lower blood glucose levels. Monitor blood glucose levels closely.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Mathew, P. T. and Augusti, K. T. Hypoglycaemic effects of onion, Allium cepa Linn. on diabetes mellitus - a preliminary report. Indian J.Physiol Pharmacol. 1975;19(4):213-217.
- Campos, K. E., Diniz, Y. S., Cataneo, A. C., Faine, L. A., Alves, M. J., and Novelli, E. L. Hypoglycaemic and antioxidant effects of onion, Allium cepa: dietary onion addition, antioxidant activity and hypoglycaemic effects on diabetic rats. Int J Food S
- El Demerdash, F. M., Yousef, M. I., and El Naga, N. I. Biochemical study on the hypoglycemic effects of onion and garlic in alloxan-induced diabetic rats. Food Chem.Toxicol. 2005;43(1):57-63.
- Kook, S., Kim, G. H., and Choi, K. The antidiabetic effect of onion and garlic in experimental diabetic rats: meta-analysis. J Med Food 2009;12(3):552-560.
- Sharma, K. K., Gupta, R. K., Gupta, S., and Samuel, K. C. Antihyperglycemic effect of onion: effect on fasting blood sugar and induced hyperglycemia in man. Indian J.Med.Res. 1977;65(3):422-429.
- Jain, R. C., Vyas, C. R., and Mahatma, O. P. Letter: Hypoglycaemic action of onion and garlic. Lancet 12-29-1973;2(7844):1491.
- Jain, R. C. and Vyas, C. R. Letter: Hypoglycaemia action of onion on rabbits. Br.Med.J. 6-29-1974;2(5921):730.
- Tjokroprawiro, A., Pikir, B. S., Budhiarta, A. A., Pranawa, Soewondo, H., Donosepoetro, M., Budhianto, F. X., Wibowo, J. A., Tanuwidjaja, S. J., Pangemanan, M., and . Metabolic effects of onion and green beans on diabetic patients. Tohoku J Exp Med 1983;
- Akash MS, Rehman K, Chen S. Spice plant Allium cepa: dietary supplement for treatment of type 2 diabetes mellitus. Nutrition 2014;30(10):1128-37.
- Eldin IM, Ahmed EM, HM AE. Preliminary study of the clinical hypoglycemic effects of Allium cepa (red onion) in type 1 and type 2 diabetic patients. Environmental health insights 2010;4:71.
Onion Overview
Onion, a common vegetable, has a long history of use in traditional medicine. It is believed to have a number of health benefits due to its high content of antioxidants, such as quercetin, as well as its anti-inflammatory properties.
It is often used to treat respiratory conditions, such as colds and flu, due to its expectorant and decongestant effects. It is also believed to be helpful in relieving symptoms of asthma and bronchitis and is thought to have antimicrobial properties, making it useful for treating infections and wounds. Additionally, onion is believed to help lower cholesterol levels, reduce the risk of heart disease, and improve blood sugar control. Most dietary supplements containing onion are an extract that contains allicin.
Dasiglucagon Hydrochloride Overview
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Dasiglucagon injection is used along with emergency medical treatment to treat severe hypoglycemia (very low blood sugar) in adults and children 6 years of age and older with diabetes. Dasiglucagon injection is in a class of medications called glucagon receptor agonists. It works by causing the liver to release stored sugar to the blood.
Onion - More Interactions
Onion interacts with 272 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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