Drug & supplement interaction

Pitcher Plant + Darunavir, Cobicistat

Darunavir, Cobicistat brand name: Prezcobix.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Pitcher Plant and Darunavir, Cobicistat in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Darunavir, Cobicistat states a food rule worth keeping to.

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Interaction report

Pitcher Plant and Darunavir, Cobicistat

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Darunavir, Cobicistat and Pitcher Plant in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Pitcher Plant at all — not against Darunavir, Cobicistat, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Pitcher Plant safety at a glance

Pitcher Plant overall Use caution Human safety data is very limited, so use cautiously and only under professional guidance.
Pregnancy Avoid Not enough safety information exists, so it is best avoided during pregnancy.
Breastfeeding Avoid No reliable safety data exists, so avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Darunavir, Cobicistat and Pitcher Plant? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Darunavir, Cobicistat’s Own FDA Label Lists

This is not an interaction — none of it involves Pitcher Plant. These are the most notable effects listed in the ADVERSE REACTIONS section of Darunavir, Cobicistat’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 2 of them are worth acting on rather than waiting out — marked below.

  • Kidney problems Worth acting on
  • Liver problems Worth acting on
  • Stomach pain
  • Diarrhea
  • A skin rash
  • Vomiting
  • Headache
  • Nausea

From the ADVERSE REACTIONS section of the FDA label for Darunavir, Cobicistat. Read the label on DailyMed › Pitcher Plant’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Pitcher Plant side to compare — that is a limit of the record, not a statement that Pitcher Plant has no side effects.

How to take them

Some Darunavir, Cobicistat Products Have a Food Rule — Pitcher Plant Should Not Break It

At least one FDA label for a product containing Darunavir, Cobicistat says to take it with food. If you take Pitcher Plant on an empty stomach out of habit, keep them separate — and take Darunavir, Cobicistat with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Darunavir, Cobicistat products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

2 DOSAGE AND ADMINISTRATION Recommended dosage: Adults and pediatric patients weighing at least 40 kg: One 800 mg/150 mg tablet taken once daily with food.

From the Dosage and Administration section of the FDA label we read for Darunavir, Cobicistat — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Darunavir, Cobicistat

This page covers Pitcher Plant only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Darunavir, Cobicistat page lists 145 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 102 moderate · 40 minor.

From our pharmacist’s overview on the Darunavir, Cobicistat page

“Prezcobix (darunavir with cobicistat) treats HIV, and it only works if it holds a steady blood level, so this list of 145 supplements deserves real care. Three carry a major rating and matter most: St.”

Reviewed by 2 · Jul 18, 2026

Open the Darunavir, Cobicistat interaction page

How much people look this up

Where Pitcher Plant and Darunavir, Cobicistat Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Pitcher Plant
Steady interest

#1,294 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Darunavir, Cobicistat
Top half

#1,339 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Pitcher Plant is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Pitcher Plant reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Pitcher Plant and Darunavir, Cobicistat records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Pitcher Plant

What is Pitcher Plant?

Pitcher Plant
  • Digestive complaints
  • Urinary tract issues
  • Smallpox (historical/traditional)
  • Pain relief
  • Skin conditions

Pitcher Plant (Sarracenia purpurea) is a carnivorous North American plant with a long history of use in traditional and folk medicine, but there is very little reliable human research to support any of its modern uses. Safety information is limited, so it should be used cautiously and avoided in pregnancy and breastfeeding. Talk to your pharmacist or doctor before trying it.

Sarracenia purpurea · Sarraceniaceae · Roots, leaves (pitchers), and whole plant · Tincture, dried herb, homeopathic preparations, capsules

An interaction check asks whether these two react with each other — it does not ask whether Pitcher Plant is a good idea for someone in your situation. Here is what our Pitcher Plant record says about it on its own.

Pitcher Plant: dosing

There is no established standard dose for Pitcher Plant. Because it has not been studied well in people, safe and effective amounts are not known.If you choose to use a product, follow the directions on the label and do not exceed the suggested amount.

From our Pitcher Plant monograph — the full record covers uses, side effects and every documented interaction.

Read the full Pitcher Plant monograph & all interactions
Medication

About Darunavir and Cobicistat

What Is Darunavir and Cobicistat Used For?

Brand name: Prezcobix

Prezcobix and Prezcobix Ped are used to treat HIV-1 (human immunodeficiency virus type 1) infection. They are always used together with other antiretroviral (anti-HIV) medicines — never alone. Both products are approved for people who are new to HIV treatment (treatment-naïve) and for those who have taken HIV medicines before (treatment-experienced), as long as certain darunavir resistance mutations are not present.

Prezcobix tablets are approved for adults and pediatric patients weighing at least 40 kg. Prezcobix Ped tablets for oral suspension extend coverage to pediatric patients 3 years of age and older weighing at least 15 kg.

See full Darunavir and Cobicistat drug information
Keep checking

Other Drugs & Pitcher Plant

Browse every other medication we’ve checked against Pitcher Plant — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Pitcher Plant against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Pitcher Plant list.

See the full Pitcher Plant interactions page
See every supplement checked against Darunavir, Cobicistat, ranked by severity
Evidence & sources

Pitcher Plant References

The 2 sources that drive our Pitcher Plant monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Pitcher Plant is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Herbs at a Glance — NIH NCCIH Source
  2. Herbal and Dietary Supplements — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Pitcher Plant and Darunavir, Cobicistat Together: Common Questions

Is it safe to take Pitcher Plant with Darunavir, Cobicistat?
We do not list a known interaction between Pitcher Plant and Darunavir, Cobicistat. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Pitcher Plant and Darunavir, Cobicistat at the same time of day?
At least one FDA label for a product containing Darunavir, Cobicistat says to take it with food. If you take Pitcher Plant on an empty stomach out of habit, keep them separate and take Darunavir, Cobicistat with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Darunavir, Cobicistat products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Darunavir, Cobicistat interact with any supplements?
Yes. Darunavir, Cobicistat has documented interactions with 145 supplements in our database — Pitcher Plant is not one of them. The Darunavir, Cobicistat interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Pitcher Plant monograph Uses, safety profile, and every drug interaction in one place Darunavir and Cobicistat drug information The full plain-English guide to this medication Darunavir, Cobicistat supplement interactions Every supplement checked against Darunavir, Cobicistat, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Darunavir, Cobicistat and Pitcher Plant?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.