Drug & supplement interaction

Salvia Divinorum + Docetaxel

Docetaxel brand name: Taxotere.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Salvia Divinorum and Docetaxel in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Salvia Divinorum and Docetaxel

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Docetaxel and Salvia Divinorum in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Salvia Divinorum at all — not against Docetaxel, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Salvia Divinorum safety at a glance

Salvia Divinorum overall Avoid It is a potent hallucinogen with no established medical use and limited safety data; it is also restricted or illegal in many areas.
Pregnancy Avoid There is no safety data, and a hallucinogen should not be used during pregnancy.
Breastfeeding Avoid There is no safety data, so it should be avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Docetaxel and Salvia Divinorum? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Salvia Divinorum and Docetaxel May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Tiredness Additional detail

    Salvia Divinorum

    “Orally or by inhalation, Salvia divinorum can cause hallucinogenic effects. These include restlessness, hyperactivity, disorientation, loss of coordination, dizziness, slurred speech, altered perceptions, changes in perception of body temperature, personal detachment or distorted body ownership, fatigue, severe mood changes, and psychosis. Most of these effects resolve within 20 minutes;”

    Salvia Divinorum · Natural Medicines adverse-effect record, reported in fatigue.

    6 sources cited
    1. 7350. Valdes LJ 3rd, Diaz JL, Paul AG. Ethnopharmacology of ska Maria Pastora (Salvia divinorum, Epling and Jativa-M.). J Ethnopharmacol 1983;7:287-312.
    2. 7351. Valdes LJ 3rd. Salvia divinorum and the unique diterpene hallucinogen, Salvinorin (divinorin) A. J Psychoactive Drugs 1994;26:277-83.
    3. 15820. Gonzalez D, Riba J, Bouso JC, et al. Pattern of use and subjective effects of Salvia divinorum among recreational users. Drug Alcohol Depend 2006;85:157-62. PubMed
    4. 72901. Bucheler, R., Gleiter, C. H., Schwoerer, P., and Gaertner, I. Use of nonprohibited hallucinogenic plants: increasing relevance for public health? A case report and literature review on the consumption of Salvia divinorum (Diviner's Sage). Pharmacopsychia
    5. 100001. Addy PH, Garcia-Romeu A, Metzger M, Wade J. The subjective experience of acute, experimentally-induced Salvia divinorum inebriation. J Psychopharmacol. 2015;29(4):426-35.
    6. 100002. El-Khoury J, Sahakian N. The association of Salvia divinorum and psychotic disorders: A review of the literature and case series. J Psychoactive Drugs. 2015;47(4):286-92.

    “Neurologic changes caused by Salvia divinorum are rapid, intense, and short-lived. Most evidence suggests a peak effect within 2 minutes following consumption by smoking, with a slower peak when consumed orally. Most symptoms cease within 20 minutes; however, the 'high' can last as long as 2 hours.”

    Salvia Divinorum · Natural Medicines adverse-effect record, reported in cluster headache.

    5 sources cited
    1. 7350. Valdes LJ 3rd, Diaz JL, Paul AG. Ethnopharmacology of ska Maria Pastora (Salvia divinorum, Epling and Jativa-M.). J Ethnopharmacol 1983;7:287-312.
    2. 7351. Valdes LJ 3rd. Salvia divinorum and the unique diterpene hallucinogen, Salvinorin (divinorin) A. J Psychoactive Drugs 1994;26:277-83.
    3. 15820. Gonzalez D, Riba J, Bouso JC, et al. Pattern of use and subjective effects of Salvia divinorum among recreational users. Drug Alcohol Depend 2006;85:157-62. PubMed
    4. 100001. Addy PH, Garcia-Romeu A, Metzger M, Wade J. The subjective experience of acute, experimentally-induced Salvia divinorum inebriation. J Psychopharmacol. 2015;29(4):426-35.
    5. 100002. El-Khoury J, Sahakian N. The association of Salvia divinorum and psychotic disorders: A review of the literature and case series. J Psychoactive Drugs. 2015;47(4):286-92.

    Docetaxel

    Listed in the ADVERSE REACTIONS section of the FDA label for Docetaxel. Read the label on DailyMed ›

  • Nausea Additional detail

    Salvia Divinorum

    “Orally, Salvia divinorum can cause nausea.”

    Salvia Divinorum · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    1 source cited
    1. 7350. Valdes LJ 3rd, Diaz JL, Paul AG. Ethnopharmacology of ska Maria Pastora (Salvia divinorum, Epling and Jativa-M.). J Ethnopharmacol 1983;7:287-312.

    Docetaxel

    Listed in the ADVERSE REACTIONS section of the FDA label for Docetaxel. Read the label on DailyMed ›

Reported for Salvia Divinorum but not commonly for Docetaxel: unsteadiness, confusion, hallucinations and anxiety or restlessness.

Effects for Docetaxel come from the ADVERSE REACTIONS section of its FDA label; effects for Salvia Divinorum come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Everything else you take

See Every Supplement That Interacts With Docetaxel

This page covers Salvia Divinorum only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Docetaxel page lists 121 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate), Adrafinil (moderate) and African Wild Potato (moderate).

By severity: 2 major · 87 moderate · 32 minor.

From our pharmacist’s overview on the Docetaxel page

“Grapefruit is the first thing I would take off the menu during docetaxel (Taxotere) chemotherapy. It blocks CYP3A4, the liver enzyme that clears docetaxel, and higher levels of a chemotherapy drug mean harsher side effects, not better results.”

Reviewed by 2 · Jul 18, 2026

Open the Docetaxel interaction page

How much people look this up

Where Salvia Divinorum and Docetaxel Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Salvia Divinorum
Steady interest

#1,189 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Docetaxel
Top half

#863 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Salvia Divinorum reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Salvia Divinorum and Docetaxel records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Salvia Divinorum

What is Salvia Divinorum?

  • Hallucinogenic or psychedelic experiences
  • Spiritual or ritual practices
  • Recreational use
  • Traditional Mazatec healing ceremonies

Salvia divinorum is a powerful hallucinogenic plant traditionally used by the Mazatec people of Mexico and now used recreationally for its short but intense mind-altering effects. There is no proven medical use, the safety is poorly studied, and it is illegal or restricted in many places. Because its effects can be unpredictable and disorienting, we do not recommend using it.

Salvia divinorum · Lamiaceae · Leaves · Dried leaves (smoked), chewed fresh leaves, leaf extracts, tinctures

An interaction check asks whether these two react with each other — it does not ask whether Salvia Divinorum is a good idea for someone in your situation. Here is what our Salvia Divinorum record says about it on its own.

Salvia Divinorum: dosing

There is no established or recommended safe dose for Salvia divinorum. The strength of leaves and extracts varies widely, and concentrated products can be far more potent than plain leaves, making effects hard to predict.Because it is not a proven medicine and is restricted in many areas, we cannot recommend any specific amount.

From our Salvia Divinorum monograph — the full record covers uses, side effects and every documented interaction.

Read the full Salvia Divinorum monograph & all interactions
Medication

About Docetaxel Injection

What Is Docetaxel Injection Used For?

Brand name: Taxotere

Docetaxel Injection is used to treat a number of serious cancers. Beizray (docetaxel injection) is approved as a single agent for locally advanced or metastatic breast cancer after prior chemotherapy has stopped working, and in combination with doxorubicin and cyclophosphamide as adjuvant (after-surgery) treatment for operable node-positive breast cancer. It is also used as a single agent for locally advanced or metastatic non-small cell lung cancer (NSCLC) after platinum-based chemotherapy has failed, and with cisplatin for chemotherapy-naive advanced NSCLC.

Beizray is used with prednisone for metastatic castration-resistant prostate cancer. It is also used with cisplatin and fluorouracil for advanced gastric adenocarcinoma (including gastroesophageal junction cancer) in patients who have not received prior chemotherapy for advanced disease, and for induction treatment of locally advanced squamous cell carcinoma of the head and neck (SCCHN).

Most-Reported Side Effects for Docetaxel

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Alopecia 16,970 reports
Madarosis 6,717 reports
Hair texture abnormal 5,993 reports
Hair colour changes 5,874 reports
Hair disorder 5,625 reports
See full Docetaxel Injection drug information
Keep checking

Other Drugs & Salvia Divinorum

Browse every other medication we’ve checked against Salvia Divinorum — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Salvia Divinorum against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Salvia Divinorum list.

See the full Salvia Divinorum interactions page
See every supplement checked against Docetaxel, ranked by severity
Evidence & sources

Salvia Divinorum References

The 6 references that drive our Salvia Divinorum monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Valdes LJ 3rd, Diaz JL, Paul AG. Ethnopharmacology of ska Maria Pastora (Salvia divinorum, Epling and Jativa-M.). J Ethnopharmacol 1983;7:287-312.
  2. Valdes LJ 3rd. Salvia divinorum and the unique diterpene hallucinogen, Salvinorin (divinorin) A. J Psychoactive Drugs 1994;26:277-83.
  3. Gonzalez D, Riba J, Bouso JC, et al. Pattern of use and subjective effects of Salvia divinorum among recreational users. Drug Alcohol Depend 2006;85:157-62. PubMed
  4. Bucheler, R., Gleiter, C. H., Schwoerer, P., and Gaertner, I. Use of nonprohibited hallucinogenic plants: increasing relevance for public health? A case report and literature review on the consumption of Salvia divinorum (Diviner's Sage). Pharmacopsychia
  5. Addy PH, Garcia-Romeu A, Metzger M, Wade J. The subjective experience of acute, experimentally-induced Salvia divinorum inebriation. J Psychopharmacol. 2015;29(4):426-35.
  6. El-Khoury J, Sahakian N. The association of Salvia divinorum and psychotic disorders: A review of the literature and case series. J Psychoactive Drugs. 2015;47(4):286-92.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Salvia Divinorum and Docetaxel Together: Common Questions

Is it safe to take Salvia Divinorum with Docetaxel?
We do not list a known interaction between Salvia Divinorum and Docetaxel. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Salvia Divinorum and Docetaxel have any of the same side effects?
Yes — our sources link each of them separately to 2 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Docetaxel interact with any supplements?
Yes. Docetaxel has documented interactions with 121 supplements in our database — Salvia Divinorum is not one of them. The Docetaxel interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Salvia Divinorum monograph Uses, safety profile, and every drug interaction in one place Docetaxel Injection drug information The full plain-English guide to this medication Docetaxel supplement interactions Every supplement checked against Docetaxel, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 6 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Docetaxel and Salvia Divinorum?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.