Scopolia - Kuvan (Sapropterin Dihydrochloride) Interaction
Herbal: Scopolia
Also Known As: Scopolia carniolica, Belladonna Scopola, Escopolia, Glockenbilsenkraut, Japanese Belladonna, Russian Krainer Tollkraut, Scopola, Scopoliae Rhizoma, Scopolie
Drug: Sapropterin Dihydrochloride
Brand names:
Kuvan
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 18, 2025
Interaction Details
There were no interactions found between Sapropterin Dihydrochloride and Scopolia. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Scopolia Overview
Scopolia is a plant genus that belongs to the Solanaceae family, which also includes tomato, potato, and tobacco. There are several species of Scopolia plants, including Scopolia carniolica, Scopolia japonica, and Scopolia tangutica. These plants are native to Asia and Europe and are known for their poisonous properties as they contain several dangerous alkaloids, such as L-hyoscyamine, atropine, and scopolamine, all of which are strong anticholinergics. These alkaloids have well known medicinally properties and are even available as prescription drugs to treat a variety of conditions, including motion sickness and spasms of the gastrointestinal (GI) tract. However, scopolia is generally considered unsafe when used for self-medication and should only be used under the supervision of a healthcare professional.
Sapropterin Dihydrochloride Overview
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Sapropterin is used along with a restricted diet to control blood phenylalanine levels in adults and children 1 month of age and older who have phenylketonuria (PKU; an inborn condition in which phenylalanine may build up in the blood and causes decreased intelligence and a decreased ability to focus, remember, and organize information). Sapropterin will only work for some people who have PKU, and the only way to tell if sapropterin will help a particular patient is to give the medication for a period of time and see whether his or her phenylalanine level decreases. Sapropterin is in a class of medications called cofactors. It works by helping the body to break down phenylalanine so it will not build up in the blood.
Scopolia - More Interactions
Scopolia interacts with 198 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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