Herb & supplement monograph

6-bromo Drug Interactions, Uses, Effectiveness, Safety & More

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS ·Updated June 2026

What is this page for?

First and foremost: how 6-bromo interacts with medications. The heart of this page is the interaction list — every drug 6-bromo is known to interact with, and how serious each one is.

But these pages have grown well beyond that into a full monograph — what 6-bromo is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy

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Reviewed by licensed pharmacists Sourced from Natural Medicines

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Interaction report

Drugs that interact with 6-bromo

0 medications have a known interaction with 6-bromo, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for 6-bromo. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
Each drug listed above links to the full report for that exact 6-bromo combination — clinical detail, likelihood, evidence level, and citations.
Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Monograph

6-bromo: Uses, Safety & Side Effects

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Reviewed June 2026 ·

The bottom line

6-Bromo (often sold as 6-bromoandrostenedione) is a synthetic steroid-derived compound marketed as an aromatase inhibitor to lower estrogen and support testosterone, mostly within the bodybuilding community. There is very little reliable human research to confirm it works or is safe, and as a hormone-altering agent it carries real risks. It is banned in sports and should not be used without medical supervision.

Part used: Not applicable (synthetic steroidal compound)
Common forms: Capsules, tablets, liquid suspensions

People commonly use it for

Lowering estrogen (aromatase inhibition)
Raising or supporting testosterone
Reducing estrogen-related side effects during steroid or prohormone cycles
Bodybuilding 'post-cycle therapy' attempts

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance

OverallUse caution

This is a hormone-altering compound with limited human safety data and real potential for harm.

PregnancyPossibly Unsafe

When used orally or parenterally. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing aromata...

Read the full pregnancy detail

BreastfeedingPossibly Unsafe

When used orally or parenterally. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing aromata...

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

6-Bromo is the common name for a synthetic steroid-related compound, usually a form of 6-bromoandrostenedione. Unlike most products on this site, it is not an herb or a plant — it is a man-made chemical sold as a dietary supplement, mostly to bodybuilders and athletes.

It is marketed as an aromatase inhibitor, meaning it is meant to block the body's process of turning testosterone into estrogen. People often take it during or after cycles of anabolic steroids or prohormones, hoping to keep estrogen low and testosterone higher.

It is important to know that this is a hormone-altering product, not a gentle wellness supplement. The amount of solid human research behind it is very small.

How it works

6-Bromo is described as a steroidal aromatase inhibitor. Aromatase is the enzyme that converts testosterone and similar hormones into estrogen. By blocking this enzyme, the compound is intended to lower estrogen and, indirectly, allow testosterone to stay higher.

This is the same general idea behind prescription aromatase inhibitors used in medicine, but those drugs are studied, dosed, and monitored carefully. For 6-Bromo, much of the proposed mechanism is based on how related compounds behave in laboratory settings rather than on careful human study.

Because hormone systems are tightly balanced, pushing estrogen too low can cause its own problems, which is one reason these products require caution.

Effectiveness

Does 6-bromo work?

Here’s what the research actually shows for each use — graded by Natural Medicines and reviewed by Dr. Brian Staiger, PharmD.

Evidence overview · 6 uses evaluated

6 Insufficient evidence

How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.

2Likely EffectiveGood evidence, though not yet conclusive.

3Possibly EffectiveSome evidence suggests a benefit.

4Possibly IneffectiveSome evidence it may not help.

5Likely IneffectiveFairly strong evidence it doesn’t help.

6IneffectiveStrong evidence it doesn’t work.

7Insufficient Reliable Evidence to RateToo little research to say either way.

For 6-bromo, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.

Also studied for 6 conditions — evidence insufficient to rate

Insufficient Reliable Evidence To Rate Athletic performance